Receptor
PDB id Resolution Class Description Source Keywords
5MQG 1.35 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH CBP01 HOMO SAPIENS CREBBP BROMODOMAIN INHIBITOR TRANSCRIPTION
Ref.: VIRTUAL SCREEN TO NMR (VS2NMR): DISCOVERY OF FRAGME FOR THE CBP BROMODOMAIN. BIOORG. MED. CHEM. LETT. V. 27 2472 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
F31 A:1201;
B:1201;
Valid;
Valid;
none;
none;
submit data
165.189 C9 H11 N O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6AY3 1.39 Å EC: 2.3.1.48 CREBBP BROMODOMAIN IN COMPLEX WITH CPD16 (5-(7-(DIFLUOROMETH METHYL-1H-PYRAZOL-4-YL)-3,4-DIHYDROQUINOLIN-1(2H)-YL)-N-METI NDOLE-3-CARBOXAMIDE) HOMO SAPIENS CREBBP BROMODOMAIN TRANSFERASE-TRANSFERASE INHIBITOR COMPL
Ref.: A UNIQUE APPROACH TO DESIGN POTENT AND SELECTIVE CY ADENOSINE MONOPHOSPHATE RESPONSE ELEMENT BINDING PR BINDING PROTEIN (CBP) INHIBITORS. J. MED. CHEM. V. 60 10151 2017
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
70% Homology Family (42)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
37 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
38 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
39 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
40 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
41 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
42 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
50% Homology Family (389)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JJ3 ic50 = 100 nM BS6 C23 H25 N5 O4 S CN1CCN(CC1....
2 6P05 ic50 = 5.9 nM YF2 C30 H28 N6 O3 S CCS(=O)(=O....
3 4IOO - BAE C6 H13 N O CC(C)(C)C(....
4 5I88 Kd = 250 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
5 5DX4 Kd = 0.137 uM E0C C20 H17 Br N2 O4 S CCN1c2ccc(....
6 6JJB ic50 = 49.5 nM BT0 C19 H16 N2 O4 S CN1c2ccc(c....
7 3JVK Kd = 118 uM GLY GLY ALY ALA PRO ARG LYS GLN n/a n/a
8 4HBX ic50 = 1.9 uM 14X C13 H17 N3 O3 S CN1Cc2cc(c....
9 4NUE Ki = 0.15 uM NUE C19 H19 N5 O3 S Cc1cc(c(c(....
10 6SB8 Kd = 0.07 uM L45 C21 H27 N3 O5 S CCN(CC)S(=....
11 5Y94 Kd = 164 nM 8QC C16 H16 Br N3 O4 S Cc1c2cc(c(....
12 6DMJ - 53W C27 H32 N4 O3 Cc1c(c(on1....
13 4HXR ic50 = 4.1 uM 1A4 C13 H10 N2 O3 S3 c1cc(cc(c1....
14 6DML - 9BM C25 H26 N4 O4 Cc1c(c(on1....
15 5TI5 ic50 = 41 uM 7CN C16 H13 Br N2 O3 S c1cc(cc(c1....
16 6VUJ ic50 = 35.2 uM RLY C23 H30 N2 O5 S CCN(CC)S(=....
17 6X7B ic50 = 27 nM ZVP C26 H24 N4 O5 S c1cc(cnc1)....
18 4O7C ic50 = 10 uM 2RK C22 H23 N5 O C1CNCCC1C2....
19 4IOQ - BAQ C4 H7 N O C1CC(=O)NC....
20 4HXK - 1AJ C11 H11 N3 O S c1csc2c1CN....
21 6S6K Kd = 0.18 uM KXK C24 H31 N3 O5 S Cc1c2c(c([....
22 2YEL ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
23 6RWJ Kd = 6.41 uM KLK C12 H16 N2 O2 Cc1c2c(c([....
24 6SA2 Kd = 0.08 uM L25 C22 H27 N3 O6 S Cc1c2c(c([....
25 6XV7 - O2Q C14 H13 F2 N5 Cc1nnc2n1n....
26 4BW4 ic50 = 631 nM 9B6 C22 H16 F3 N5 O4 Cc1c(c(on1....
27 4O72 ic50 = 1 uM 2R4 C25 H19 N O3 S c1ccc2c(c1....
28 5F63 Kd = 12 nM 5W2 C28 H35 Cl F N7 O3 S Cc1cnc(nc1....
29 5HLS ic50 = 0.039 uM 62G C20 H16 Cl N3 O2 Cc1c-2c(on....
30 4HBW ic50 = 4.8 uM 14Z C11 H15 N3 O3 S CCNS(=O)(=....
31 4OGI Kd = 37 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
32 6WW8 - YR0 C31 H32 N6 O4 S CN(C)C(=O)....
33 5TI7 ic50 = 11 uM 7CQ C17 H19 Br N2 O4 S COc1ccc(cc....
34 4J0S ic50 = 0.382 uM 1H3 C18 H17 N O3 Cc1c(c(on1....
35 6Q3Y Kd = 54 nM HG5 C30 H38 N6 O2 CC[C@@H]1C....
36 6SAJ Kd = 0.05 uM L2Z C23 H27 N3 O6 S Cc1c2c(c([....
37 4F3I Kd = 36.1 nM 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
38 4QZS Kd = 89 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
39 6AFR ic50 = 70 nM 9E3 C13 H10 F N3 O c1cc2c(ccc....
40 4WIV Kd = 550 nM 3P2 C21 H23 N5 O Cc1c(c(on1....
41 6VUF ic50 = 147 uM RLV C14 H20 N2 O3 S CCCNS(=O)(....
42 3P5O Kd = 55.2 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
43 4UIX ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
44 4HXS ic50 = 4.1 uM 1A3 C16 H14 N2 O3 S2 c1ccc(cc1)....
45 5HM0 ic50 = 0.44 uM 62V C18 H13 Cl N2 O Cc1c-2c(on....
46 5DLX Kd = 2 uM 5D2 C25 H33 Cl N8 O Cc1nnc2n1n....
47 5TI2 ic50 = 24 uM 7CJ C16 H15 F N2 O3 S c1cc(cc(c1....
48 5D3H Kd = 7.9 uM 57G C20 H27 N3 O6 S CCc1c(c([n....
49 6E4A Kd = 44 nM HRY C29 H34 Cl N7 O CN1C=C(C=C....
50 4MEP ic50 = 4.7 uM 24Y C19 H14 Cl N5 O Cc1cccnc1n....
51 4YH4 ic50 = 26 uM Y81 C20 H15 N3 O2 c1ccc(cc1)....
52 5D3N Kd = 9.2 uM L40 C18 H23 N3 O4 S CCc1c(c([n....
53 6C7R Kd = 2.2 nM EO4 C24 H25 N7 O2 Cc1c(c(on1....
54 6WGX ic50 = 0.15 uM U0D C31 H36 F3 N7 Cc1cc(cc(c....
55 6HOV - FER C10 H10 O4 COc1cc(ccc....
56 5D26 Kd = 0.81 uM L28 C19 H26 N4 O5 S CCc1c(c([n....
57 3MUK Kd = 380 uM ALA THR PRK ALA ALA ARG LYS SER n/a n/a
58 4J3I Kd = 8.93 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
59 6X7D ic50 = 388 nM UT4 C19 H18 N2 O4 S c1cc2c(cc1....
60 4QB3 Kd = 3.4 uM 30M C17 H21 N3 O2 CC(=O)NCCC....
61 4LZS Kd = 16 uM L46 C11 H16 N2 O2 CCc1c(c([n....
62 6HDQ ic50 = 5.01 uM FZE C30 H37 F2 N5 O Cc1cc(cnc1....
63 4O71 ic50 = 18 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
64 4CFL Kd = 1.33 uM 8DQ C19 H18 N2 O2 c1ccc(cc1)....
65 4C67 - L5S C15 H12 N4 S Cc1nnc2n1-....
66 6V1K - 5SW C20 H23 N3 O3 CN1C=C(c2c....
67 4QR3 ic50 = 1.4 uM BNJ C14 H16 N2 O3 S2 c1cc(cc(c1....
68 4ZC9 - 4MW C38 H37 Cl N8 O7 S Cc1c(sc-2c....
69 4MEO - 25V C18 H16 N2 O2 Cc1cc(c2cc....
70 6UVM Kd = 510 uM QJA C11 H13 N O S2 CC(=O)N1CC....
71 4LRG ic50 = 0.026 uM 1XB C20 H18 Cl N3 O2 S Cc1c(sc-2c....
72 6CKS ic50 = 0.015 uM F5Y C23 H23 N3 O4 S CCS(=O)(=O....
73 6DJC Ki = 232.8 nM CF6 C48 H54 Cl2 N10 O2 S2 Cc1c(sc-2c....
74 5TI3 ic50 = 44 uM 7CG C16 H14 Br2 N2 O3 S c1cc(cc(c1....
75 4HXP - 1A5 C10 H10 N2 O3 c1cc(ccc1C....
76 6PSB ic50 = 24 uM Y18 C17 H19 N3 O2 CN1C[C@H](....
77 6CD4 ic50 = 5.14 uM EX1 C33 H42 N8 O3 CC(C)N1c2c....
78 4O7E ic50 = 5.7 uM 2RN C20 H15 N3 O c1ccc(cc1)....
79 4O74 ic50 = 0.025 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
80 4BW2 ic50 = 6.31 uM UTH C24 H24 N4 O3 Cc1c(c(on1....
81 5CS8 ic50 = 2.29 uM EB8 C21 H18 N2 O5 S CCN1c2ccc(....
82 3U5J Kd = 2.46 uM 08H C17 H13 Cl N4 Cc1nnc2n1-....
83 5EIS Kd = 1.8 uM 5OU C14 H13 Cl N4 O2 CCn1cnc2c1....
84 6FO5 Kd = 0.19 uM DZH C25 H26 N6 O5 S CCn1cnc2c1....
85 6V1L Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
86 3U5L Kd = 0.64 uM 08K C17 H14 Cl N5 Cc1nnc2n1-....
87 4QR4 ic50 = 0.25 uM BNK C14 H15 Cl N2 O3 S2 c1cc(c(cc1....
88 4O7A ic50 = 19 uM 2RF C16 H10 Cl2 N2 O3 c1cc(cc(c1....
89 5F61 Kd = 35 nM 5W0 C26 H34 F N7 O2 S Cc1cnc(nc1....
90 4HXN - 1A7 C9 H6 F N O S c1ccc(c(c1....
91 6DL2 Ki = 33 nM GUJ C17 H17 N3 O S Cc1c(c2c(s....
92 5Z5U - 96U C12 H10 N4 O2 c1cn(cn1)c....
93 5TI4 ic50 = 26 uM 7CM C16 H14 Cl F N2 O3 S c1cc(cc(c1....
94 5Y8C ic50 = 0.16 uM 8P9 C16 H15 Cl N2 O5 S Cc1c2cc(c(....
95 4NUD Ki < 0.0845 uM NUD C18 H17 N5 O3 S Cc1cc(c(cc....
96 4O7B ic50 = 20 uM 2RJ C26 H26 F N5 O Cc1cccc(c1....
97 5CPE ic50 = 0.45 uM EB2 C20 H24 N2 O3 S CCN1c2ccc(....
98 5MLI ic50 = 130 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
99 5DW2 Kd = 1.44 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
100 5D3P Kd = 7.4 uM 57E C19 H21 N3 O4 S CCc1c(c([n....
101 4PCE ic50 = 7 uM 2N0 C17 H19 N O CCc1cc2c(n....
102 5D25 Kd = 0.46 uM 56M C19 H25 N3 O5 S CCN(CC)S(=....
103 5DLZ Kd = 1.8 uM 5D1 C28 H35 N3 O3 Cc1cccc(c1....
104 5Y8W ic50 = 0.23 uM 8PU C15 H13 Br N2 O5 S Cc1c2cc(c(....
105 4J0R ic50 = 0.386 uM 1H2 C18 H17 N O3 Cc1c(c(on1....
106 6MH7 ic50 = 1.3 uM JQY C26 H27 F N6 Cc1ccc(cc1....
107 5F60 Kd = 43 nM 5VZ C26 H34 Cl N7 O2 S Cc1cnc(nc1....
108 5Z5V ic50 = 287 nM 96X C15 H14 N4 O2 CC(=O)Nc1c....
109 4HXO - 1A6 C11 H10 N4 O S Cc1cc(on1)....
110 5CRM ic50 = 1.09 uM EB5 C15 H16 N2 O3 S CCNS(=O)(=....
111 6YQN ic50 = 0.72 uM P8T C32 H28 Cl N7 O2 S Cc1c(sc-2c....
112 5CQT Kd = 0.124 uM EB3 C19 H22 N2 O3 S CCN1c2ccc(....
113 5KHM Ki = 5.012 nM XNH C25 H33 N7 O3 C[C@@H]1C(....
114 6XV3 - O2B C28 H33 N9 O Cc1nnc2n1c....
115 4Z1S ic50 = 0.79 uM 559 C23 H21 Cl N6 Cc1nnc2n1-....
116 4MR3 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
117 5MKZ ic50 = 20 uM RNK C11 H12 Cl N3 O S Cc1ccsc1CN....
118 5ULA Ki = 77 nM 5MJ C20 H19 Cl N2 O3 CC1=C(CCC1....
119 4O78 ic50 = 4.6 uM SAV C21 H22 N6 O3 Cc1c2ccc(c....
120 6XVC - O32 C22 H21 N5 O2 Cc1nnc2n1c....
121 4OGJ Kd = 164 nM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
122 5A85 ic50 = 5.01 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
123 5TI6 ic50 = 21 uM 7CO C16 H14 F2 N2 O3 S c1cc(cc(c1....
124 6MAU - JBS C30 H32 N6 O3 Cc1c(c(on1....
125 6S4B Kd = 0.14 uM KUH C22 H29 N3 O5 S CCN(CC)S(=....
126 6Q3Z Kd = 44 nM HG8 C29 H38 N6 O2 S CC[C@@H]1C....
127 6V0U Kd = 392 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
128 6VUC ic50 = 144 uM RLS C16 H22 N2 O3 S CN1C[C@H](....
129 4MR4 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
130 4QR5 ic50 = 0.06 uM BNM C18 H21 N3 O4 S2 c1c(cc(cc1....
131 4MEQ - 25O C12 H11 N5 Cc1cc(n2c(....
132 4O77 ic50 = 2.5 uM 2RE C20 H14 F N3 O c1cc(ccc1c....
133 6XUZ - O1W C24 H33 N9 O2 Cc1nnc2n1c....
134 5EI4 ic50 = 26.4 uM 5NV C17 H17 Cl N8 O2 S CCn1c(nc2c....
135 5CY9 Kd = 0.218 uM E0A C17 H20 N2 O3 S CCCCS(=O)(....
136 6MH1 ic50 = 1.7 uM JQP C26 H27 F N6 Cc1cc(cc(c....
137 5CRZ ic50 = 0.45 uM EB7 C19 H14 Cl F N2 O3 S CCN1c2ccc(....
138 5Y93 ic50 = 2.27 uM 8Q9 C23 H27 Br N4 O7 S Cc1c2cc(c(....
139 5AD2 Kd = 63 nM ETU C24 H30 Cl N7 O2 C[C@@H]1C(....
140 4E96 ic50 = 0.22 uM 0NS C16 H17 N3 O4 S CN1Cc2cc(c....
141 5D0C Kd = 2.34 uM E0B C21 H25 N3 O4 S CCN1c2ccc(....
142 4O7F ic50 = 13 uM 2RQ C25 H24 F N5 O2 COc1ccccc1....
143 5CP5 Kd = 1.234 uM EB0 C19 H15 F N2 O3 S CCN1c2ccc(....
144 4CFK Kd = 1.83 uM LY2 C19 H17 N O3 c1ccc(cc1)....
145 5D3R - 57C C23 H31 N3 O4 S CCCc1c(c([....
146 4NUC Ki = 0.91 uM 435 C19 H18 N4 O3 S Cc1cc(cc(c....
147 4HXL ic50 = 2.2 uM 1A9 C22 H25 N3 O4 S3 c1cc(sc1)S....
148 6CIY ic50 = 0.41 uM F3J C34 H42 N8 O3 CN1CCN(CC1....
149 5D3L Kd = 0.88 uM 57F C21 H29 N3 O5 S CCc1c(c([n....
150 4A9L - P9L C14 H19 N3 O4 S CN1Cc2cc(c....
151 4XYA Kd = 1370 nM 43S C13 H8 Br N5 O c1coc2c1cc....
152 4C66 - H4C C17 H16 Cl N4 S CCc1cc2c(s....
153 6UWU ic50 ~ 70 nM QKP C27 H34 N2 O6 Cc1cc(cc(c....
154 4O76 ic50 = 0.13 uM 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
155 5LJ2 ic50 = 10 uM 6XW C25 H32 N6 O4 S CC1=Cc2c(c....
156 6CD5 - R4L C35 H44 N8 O3 CN1CCN(CC1....
157 5I80 Kd = 62 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
158 4O75 ic50 = 21 uM 2RC C23 H26 F N6 O9 P CC1(C(=O)N....
159 5NNF - PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU n/a n/a
160 3ZYU ic50 = 0.1 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
161 4Z1Q ic50 = 0.015 uM 558 C23 H21 Cl N6 Cc1nnc2n1-....
162 6SA3 Kd = 0.42 uM L2N C23 H30 N4 O5 S Cc1c2c(c([....
163 5IGK Kd = 41.8 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
164 5Y1Y ic50 = 0.98 uM HNQ C9 H6 N2 O3 c1cc2c(ccc....
165 5Z5T - 96R C12 H10 N4 O c1cc2c(cc(....
166 6V1U - QMG C20 H19 N3 O2 Cc1ccc(cc1....
167 5KDH Ki = 0.37 uM 6RX C18 H17 N3 O4 CCN1C2=C([....
168 4PS5 ic50 = 0.29 uM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
169 5D24 Kd = 5.8 uM L26 C18 H21 N3 O4 CCc1c(c([n....
170 5ACY Kd = 6.4 nM 9S3 C30 H35 N3 O C[C@H]1C[C....
171 5HCL ic50 = 6 mM 5Y9 C4 H9 N O CC(=O)N(C)....
172 5COI ic50 = 2.58 uM 55K C20 H22 N2 O5 S CCN1c2ccc(....
173 6UWX Kd = 290 uM QKD C12 H17 N O2 S2 CCOC(=O)N1....
174 5Y8Y Kd = 82 nM 8PX C16 H15 Br N2 O5 S Cc1c2cc(c(....
175 4HXM ic50 = 0.79 uM 1A8 C17 H17 N3 O4 S3 CCCC(=O)Nc....
176 5F62 Kd = 6.8 nM 5W1 C26 H33 Cl F N7 O2 S Cc1cnc(nc1....
177 5D3S Kd = 1.3 uM 579 C20 H24 F N3 O5 S CCc1c(c([n....
178 6YQP ic50 = 1.35 uM P8N C29 H27 Cl N6 O3 S Cc1c(sc-2c....
179 6AJX Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
180 4LYW Kd = 237 nM 21Q C20 H27 N3 O5 S CCc1c(c([n....
181 4HBV ic50 = 23 uM 15E C9 H9 Br N2 O CN1Cc2cc(c....
182 5LUU Kd = 8.63 uM 77X C15 H17 N3 O CCC(=O)N1C....
183 4YH3 ic50 = 26 uM Y80 C24 H20 N2 O3 COc1ccc(cc....
184 6AJV Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
185 6CZV ic50 = 0.23 uM FOY C17 H16 N2 O2 Cc1c(c(on1....
186 4X2I ic50 = 0.35 uM 3X0 C18 H17 Cl N4 Cc1nnc2n1-....
187 6CJ1 ic50 = 6.31 uM FND C34 H44 N8 O3 CC[C@H](C)....
188 5F5Z Kd = 86 nM 5VY C26 H35 N7 O2 S Cc1cnc(nc1....
189 6UVJ Kd = 20 uM QJ1 C11 H15 N O2 S2 COC(=O)N1C....
190 6FNX ic50 = 12.6 uM DYZ C14 H14 N4 O2 CCn1cnc2c1....
191 4HBY ic50 = 4.4 uM 13F C15 H15 N3 O3 S CN1Cc2cc(c....
192 5D3J Kd = 5.7 uM L33 C20 H27 N3 O4 S CCc1c(c([n....
193 6AJY Kd = 5.3 uM A0R C16 H14 O4 COc1ccccc1....
194 3MUL - GLY GLY BTK ALA PRO ARG LYS GLN n/a n/a
195 4LR6 ic50 = 33 uM 1XA C10 H10 N2 O Cc1c(c(on1....
196 5AD3 Kd = 7.9 nM K6K C26 H30 N10 O3 CN(CCOc1cc....
197 4PCI ic50 = 7.5 uM 2NJ C16 H16 N2 O CN1c2ccccc....
198 5D3T Kd = 12 uM 56Y C19 H23 N3 O3 CCc1c(c([n....
199 6SAH Kd = 0.26 uM L2W C23 H29 N3 O5 S Cc1c2c(c([....
200 5LJ1 ic50 > 0.0000316 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
201 4O70 ic50 = 19 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
202 4XY9 Kd = 4651 nM 43U C12 H10 Br N5 O COc1ccc(cc....
203 3MXF - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
204 5CFW Kd = 0.78 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
205 5A5S ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
206 4UIY ic50 = 0.00000001 M 5V2 C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
207 6PS9 ic50 = 79 uM Y17 C18 H21 N3 O2 CN1C[C@@H]....
208 4LZR Kd = 20 uM LOC C22 H25 N O6 CC(=O)N[C@....
209 6PRT ic50 = 2120 uM OWA C8 H13 N O3 CN1C[C@H](....
210 4BW1 ic50 = 1.26 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
211 6YQO ic50 = 4.53 uM P8Q C33 H36 Cl N7 O4 S Cc1c(sc-2c....
212 4MEN - 25K C15 H17 N5 Cc1ccc(cc1....
213 6CIS ic50 = 0.3 uM X26 C37 H48 N8 O3 CC(C)Oc1cc....
214 6CKR ic50 = 0.05 uM F5V C21 H20 N4 O3 S Cn1cc(cn1)....
215 4UIZ ic50 = 0.00001995 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
216 5KJ0 ic50 = 130 nM 6TB C29 H41 N7 O3 CC[C@@H]1C....
217 4KV1 - THR PHE ALY SER ILE MET LYS n/a n/a
218 5EGU Kd = 1.4 uM 5NQ C23 H32 N8 O2 S CCCCc1c(nc....
219 5Y8Z ic50 = 0.62 uM 8Q3 C16 H15 Br N2 O4 S Cc1cc2c(cc....
220 6VUB ic50 = 629 uM RLG C11 H13 N O CN1C[C@H](....
221 4BW3 ic50 = 501 nM 9BM C25 H26 N4 O4 Cc1c(c(on1....
222 3U5K - 08J C18 H13 Cl F N3 Cc1ncc2n1-....
223 6FGH - 6RZ C10 H16 N2 O2 S Cc1c(cccn1....
224 6FG6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
225 6FGG Kd = 17 uM D9B C18 H20 N4 O4 CN1C=C(C=C....
226 5MGJ Kd = 51 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
227 6FGV - D9T C14 H21 N3 O2 CN1C=C(C=C....
228 6FGL ic50 = 24 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
229 5OR8 - JR4 C17 H18 F N3 O3 S Cc1cc2c(cc....
230 5FE0 - ALY C8 H16 N2 O3 CC(=O)NCCC....
231 5LVR Kd = 250 uM 78Y C10 H10 N4 O Cc1c(nn(n1....
232 5FDZ Kd = 6.8 uM 5X0 C21 H24 N2 O5 CNC(=O)c1c....
233 5FE1 - 12Q C10 H9 N O CN1c2ccccc....
234 5FE6 Kd = 6910 uM 5WZ C9 H16 N2 O C1CC1C(=O)....
235 5FE2 - 5WV C9 H9 N O CN1Cc2cccc....
236 5FE7 Kd = 488 uM 5WU C10 H14 N2 O2 Cc1c2c(n(n....
237 5FE8 - 5WT C13 H14 N2 O2 CC1=CC(=O)....
238 5FE4 - 5WY C9 H9 N O3 c1cc(c2c(c....
239 5FE9 Kd = 20.98 uM 5WS C12 H14 N2 O3 S CC1=CC(=O)....
240 5FE5 - 2QC C9 H9 N3 S c1cc(ccc1C....
241 5MKX ic50 = 20 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
242 5LVQ Kd = 73 uM 2LX C13 H17 N O3 CNC(=O)c1c....
243 5FE3 - 5WX C8 H8 N2 O2 COc1cccc2c....
244 6C7Q - EO1 C25 H23 N7 O2 Cc1c(c(on1....
245 2YEM ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
246 5JWM ic50 = 3.09 nM 6ON C54 H66 Cl2 N10 O9 S2 Cc1c(sc-2c....
247 5UOO Ki = 1.4 nM 8FV C26 H21 N5 O2 Cc1c(c(on1....
248 3QZS Kd = 99 uM LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
249 3QZT - LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
250 5U6V ic50 = 21 nM 7WY C22 H19 Cl N6 Cc1c-2n(nn....
251 5O3A - 31P C23 H23 Cl N4 O3 CC[C@H]([C....
252 5DFD - 59E C23 H21 N5 O3 Cc1nnc2n1-....
253 5XHK - LDR C13 H9 N O c1ccc2c(c1....
254 5O3D - 9J5 C23 H23 Cl N4 O3 CC[C@H]([C....
255 6YTM Kd = 65 nM PMW C22 H25 Cl N4 O2 S CC[C@H]([C....
256 6VIY Ki = 1.1 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
257 5IG6 Kd = 213.7 uM 6B3 C27 H18 N2 O4 c1ccc2c(c1....
258 5O3G - 9J8 C25 H26 Cl N5 O2 CCNC(=O)[C....
259 4J1P Kd = 0.206 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
260 5O3I - 9HN C27 H29 Cl N4 O3 Cc1nnc2n1-....
261 5UEW - 87D C20 H20 N2 O5 S CN1C=C(C(=....
262 5O3B - 9HZ C24 H23 Cl N4 O3 Cc1nnc2n1-....
263 5O3E - 9HW C23 H24 Cl N5 O2 CCNC(=O)[C....
264 3ONI - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
265 6K04 Ki = 3.1 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
266 5O39 - 31O C22 H21 Cl N4 O3 Cc1nnc2n1-....
267 5O3H - 9HQ C23 H24 Cl N5 O2 CCNC(=O)[C....
268 5O3C - 9J2 C22 H21 Cl N4 O3 Cc1nnc2n1-....
269 4MR6 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
270 6MOA Kd = 2.5 nM JW4 C25 H22 N4 O Cc1ccc2c(c....
271 5DW1 ic50 = 0.08 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
272 5DFC - EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
273 4MR5 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
274 5O3F - 9HT C24 H26 Cl N5 O2 CC[C@H]([C....
275 2WP1 - LYS ALA PRO ARG ALY GLN LEU ALA THR LYS n/a n/a
276 4FLP Kd = 190.1 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
277 4KCX Kd = 37 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
278 4A9I - P9I C15 H13 N2 O C/C(=C/1C=....
279 4UYH ic50 = 0.00000001 M 9S3 C30 H35 N3 O C[C@H]1C[C....
280 4A9H - TVP C12 H15 N O C[C@H]1CCc....
281 4A9F - MB3 C5 H9 N O CN1CCCC1=O
282 4ALG ic50 = 0.5 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
283 2YEK ic50 = 32.5 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
284 2YDW Kd = 46 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
285 4A9J - TYL C8 H9 N O2 CC(=O)Nc1c....
286 4A9M ic50 = 0.5 uM P9M C17 H22 N2 O3 S Cc1ccc(cc1....
287 4ALH - A9P C11 H11 N O Cc1c(c(on1....
288 4A9E - 3PF C9 H10 N2 O CN1Cc2cccc....
289 4A9O - A9O C12 H13 N O CCc1c(c(no....
290 4AKN ic50 = 0.79 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
291 4A9N ic50 = 1.5 uM A9N C15 H16 N2 O3 S Cc1ccc(cc1....
292 4KV4 - THR PHE ALY SER ILE MET LYS n/a n/a
293 5UEZ Ki = 970 nM 89G C18 H16 N2 O3 CN1C(=O)C=....
294 6VIX Ki = 1.3 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
295 5UF0 Ki = 160 uM 89J C12 H13 N3 O CNC1=CC(=O....
296 5UEU - 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
297 4Z93 Kd = 44.6 nM 4LD C24 H23 N5 O2 Cc1c(c(n[n....
298 5UEY Ki = 5.1 nM 88M C22 H24 F2 N2 O5 S CCOC1=CC(=....
299 5UEX Ki = 1.5 nM 89D C24 H26 F2 N2 O5 S CCS(Nc1ccc....
300 5I8B ic50 = 0.11 uM 69F C23 H22 N2 O2 C[C@@H]1CC....
301 5I8G Kd = 0.03 uM 69E C22 H22 N6 O C[C@@H]1CC....
302 5N18 Kd = 2.1 uM 8HZ C21 H19 N3 O Cc1ccc(cc1....
303 5MLJ Ki = 1.4 nM 9ST C17 H21 Br N4 O CN1C[C@H](....
304 6J3P Kd = 105 nM B8O C21 H25 N5 O3 CN1C[C@H](....
305 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
306 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
307 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
308 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
309 3P1D - MB3 C5 H9 N O CN1CCCC1=O
310 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
311 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
312 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
313 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
314 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
315 5MQK - QPR C11 H11 N O CC(=O)c1cn....
316 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
317 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
318 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
319 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
320 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
321 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
322 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
323 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
324 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
325 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
326 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
327 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
328 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
329 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
330 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
331 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
332 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
333 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
334 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
335 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
336 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
337 4BJX ic50 = 22 nM 73B C25 H23 Cl N2 O3 C[C@H]1C[C....
338 4UYD ic50 = 79.4 uM V1T C10 H11 N3 O2 CN1c2ccc(c....
339 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
340 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
341 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
342 5E9I - F60 C8 H7 N O c1cc(cc2c1....
343 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
344 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
345 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
346 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
347 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
348 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
349 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
350 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
351 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
352 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
353 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
354 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
355 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
356 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
357 5E9M - BAE C6 H13 N O CC(C)(C)C(....
358 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
359 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
360 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
361 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
362 7K6R - 9ST C17 H21 Br N4 O CN1C[C@H](....
363 7KDW - WCV C20 H21 N5 O C#CCNc1ncc....
364 7KDZ - WCS C22 H30 N6 O3 S CN(C)CCCOc....
365 7K6S - VYM C13 H16 N2 O c1cc2c(cc1....
366 5A7C ic50 = 0.00018 M 5D4 C10 H20 N2 O2 CC(=O)NCCC....
367 5TPX Kd = 280 nM 7H7 C21 H24 N6 Cc1nnc2n1n....
368 6MO8 - JWD C19 H17 N3 O2 Cc1c(c(on1....
369 6ONY - HWV C28 H30 F N3 O4 CCNC(=O)c1....
370 6JKE - BUX C13 H6 Cl2 N2 O4 c1cc(cc(c1....
371 6MO7 - JWA C19 H25 N3 O4 S Cc1ccc(cc1....
372 6MO9 - JVY C19 H21 N3 O3 S Cc1c(c(on1....
373 3AQA - BYH C17 H16 N4 S2 CN1c2ccccc....
374 6K05 Ki = 95.5 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
375 5WUU ic50 = 0.81 uM 7UU C18 H18 N2 O3 S CN(CCCNC1=....
376 5N17 Kd = 4.8 uM 8FK C19 H18 N2 O3 S CN1c2ccc(c....
377 5N16 Kd = 5 uM 8FN C22 H15 N5 O2 S c1ccc2c(c1....
378 6VIZ Ki = 120 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
379 6VIW Ki = 21.6 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
380 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
381 5ML0 - P2L C11 H17 Cl N4 O CN1CCC[C@H....
382 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
383 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
384 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
385 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
386 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
387 5VOM ic50 = 0.79 uM 9GY C24 H23 N3 O4 C[C@H]1CN(....
388 2RI7 - ALA ARG THR MLY GLN THR ALA ARG LYS n/a n/a
389 6J3O Kd = 2.4 uM B4L C13 H19 N5 O CN1CCC[C@H....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: F31; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 F31 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: F31; Similar ligands found: 1284
No: Ligand Similarity coefficient
1 VNL 0.9986
2 INO 0.9771
3 IHB 0.9770
4 NNO 0.9768
5 DHB 0.9764
6 QSB 0.9763
7 2HO 0.9756
8 9TW 0.9749
9 4A3 0.9747
10 93K 0.9747
11 EUG 0.9744
12 FHB 0.9743
13 CHB 0.9740
14 MYJ 0.9736
15 4NC 0.9736
16 XX2 0.9734
17 3HM 0.9730
18 P9P 0.9730
19 JLZ 0.9668
20 OW4 0.9665
21 0HO 0.9657
22 DNF 0.9636
23 7WR 0.9629
24 OVM 0.9629
25 0HN 0.9612
26 4HM 0.9612
27 V55 0.9608
28 F0J 0.9581
29 3NY 0.9574
30 VXX 0.9572
31 4AV 0.9568
32 TWO 0.9567
33 3MB 0.9563
34 BDP 0.9563
35 1F1 0.9561
36 SLS 0.9549
37 3A9 0.9541
38 6NT 0.9537
39 J9T 0.9531
40 ABI 0.9530
41 2ZM 0.9526
42 JAW 0.9526
43 2HU 0.9519
44 SKM 0.9519
45 15N 0.9517
46 EOL 0.9516
47 L99 0.9515
48 DHK 0.9515
49 XX3 0.9506
50 ICO 0.9495
51 4M4 0.9494
52 QSH 0.9493
53 0F9 0.9492
54 3ID 0.9488
55 HA5 0.9484
56 8WO 0.9483
57 X0V 0.9483
58 GDE 0.9482
59 5NI 0.9479
60 53C 0.9479
61 0JD 0.9478
62 PDC 0.9475
63 6NI 0.9474
64 NMJ 0.9473
65 4CS 0.9473
66 3NT 0.9471
67 E1T 0.9471
68 GAB 0.9470
69 9ZE 0.9468
70 JDN 0.9467
71 JB8 0.9465
72 OVP 0.9464
73 PD2 0.9464
74 SE2 0.9460
75 3PF 0.9459
76 D48 0.9458
77 5RN 0.9458
78 3OC 0.9456
79 3AB 0.9453
80 DMD 0.9450
81 G3E 0.9449
82 J5I 0.9449
83 5OB 0.9449
84 KOJ 0.9446
85 3HB 0.9445
86 WCE 0.9444
87 RD4 0.9444
88 OVV 0.9443
89 3BZ 0.9443
90 OW7 0.9443
91 GYE 0.9442
92 E7Z 0.9438
93 0W8 0.9436
94 BRT 0.9432
95 5RO 0.9428
96 HX3 0.9427
97 HQD 0.9422
98 4FH 0.9418
99 FGZ 0.9410
100 2AL 0.9409
101 5QY 0.9409
102 BGC 0.9408
103 8G0 0.9407
104 4SX 0.9406
105 M0W 0.9405
106 54G 0.9402
107 5HN 0.9401
108 7MU 0.9398
109 GTQ 0.9398
110 HQJ 0.9394
111 4Z4 0.9393
112 EKZ 0.9391
113 AZ9 0.9389
114 4AA 0.9388
115 0N7 0.9384
116 IFP 0.9384
117 LT2 0.9381
118 8ZE 0.9380
119 97T 0.9378
120 BZ3 0.9378
121 9FE 0.9373
122 GZL 0.9371
123 4A5 0.9371
124 L5V 0.9367
125 C2Y 0.9361
126 KUF 0.9360
127 92P 0.9359
128 VOH 0.9356
129 42J 0.9352
130 9FL 0.9348
131 7VS 0.9348
132 BZ2 0.9347
133 8WT 0.9346
134 4ZA 0.9346
135 6R8 0.9345
136 6RQ 0.9342
137 M0Q 0.9340
138 5XC 0.9336
139 LNR 0.9336
140 463 0.9335
141 SRO 0.9332
142 MWP 0.9329
143 HLZ 0.9329
144 AEH 0.9327
145 LDP 0.9323
146 CN0 0.9322
147 ONR 0.9322
148 ORO 0.9322
149 ZXD 0.9321
150 MB1 0.9318
151 1IT 0.9314
152 KKN 0.9312
153 AJY 0.9310
154 4WL 0.9310
155 AHR 0.9309
156 EA1 0.9304
157 ASC 0.9302
158 M1H 0.9302
159 H7Y 0.9301
160 069 0.9300
161 N2I 0.9299
162 ESP 0.9298
163 3IT 0.9298
164 2BG 0.9297
165 9CA 0.9295
166 GLC 0.9291
167 SYA 0.9290
168 5RG 0.9289
169 4P5 0.9289
170 1P7 0.9288
171 M1E 0.9288
172 DIN 0.9286
173 OXC 0.9286
174 FE DB1 0.9281
175 KJU 0.9278
176 Q88 0.9277
177 3M0 0.9274
178 DBH 0.9272
179 I3A 0.9271
180 5B1 0.9270
181 J9Q 0.9269
182 PQK 0.9268
183 4XS 0.9268
184 ADA 0.9265
185 5M0 0.9263
186 GTR 0.9263
187 KTW 0.9262
188 ES7 0.9261
189 A7W 0.9261
190 F12 0.9260
191 0W1 0.9260
192 2LY 0.9259
193 Q6T 0.9259
194 IJZ 0.9258
195 DNC 0.9256
196 HIS 0.9256
197 3F0 0.9255
198 COU 0.9254
199 ESI 0.9254
200 XXG 0.9253
201 UFV 0.9253
202 4XV 0.9253
203 92K 0.9252
204 GAL 0.9251
205 3R6 0.9249
206 8GC 0.9249
207 OCH 0.9246
208 7NI 0.9245
209 CWS 0.9245
210 PEY 0.9245
211 3HA 0.9244
212 34D 0.9243
213 FOT 0.9242
214 0FK 0.9240
215 BCU 0.9239
216 BZJ 0.9238
217 URC 0.9237
218 ICB 0.9236
219 K97 0.9236
220 GCU 0.9236
221 AW5 0.9235
222 6TZ 0.9235
223 MRW 0.9235
224 1P8 0.9233
225 XCZ 0.9233
226 2AQ 0.9233
227 03V 0.9232
228 DA4 0.9232
229 MPV 0.9232
230 5MK 0.9231
231 2HQ 0.9229
232 8HC 0.9229
233 3DM 0.9229
234 ESX 0.9228
235 AY4 0.9228
236 86J 0.9227
237 R20 0.9226
238 4XR 0.9226
239 ES2 0.9225
240 ES0 0.9223
241 X0W 0.9222
242 42C 0.9220
243 PRZ 0.9219
244 R8S 0.9219
245 XQ0 0.9216
246 2HC 0.9215
247 NOJ 0.9215
248 GV9 0.9214
249 G4D 0.9214
250 KT7 0.9213
251 4FS 0.9213
252 EN1 0.9213
253 DHS 0.9213
254 SVD 0.9211
255 A29 0.9210
256 UNC 0.9209
257 RM1 0.9209
258 4ME 0.9209
259 ASO 0.9208
260 6CS 0.9208
261 DGJ 0.9204
262 SX1 0.9204
263 ES5 0.9203
264 D1X 0.9203
265 2A9 0.9202
266 XIY 0.9202
267 MAJ 0.9201
268 JG8 0.9199
269 5WV 0.9198
270 CWM 0.9197
271 DBJ 0.9197
272 1LQ 0.9194
273 KYA 0.9194
274 HQT 0.9193
275 2O6 0.9191
276 H42 0.9190
277 AKH 0.9190
278 GJP 0.9188
279 1HN 0.9187
280 6VD 0.9185
281 4HC 0.9182
282 0P6 0.9182
283 FA1 0.9182
284 9TZ 0.9180
285 5GU 0.9180
286 2FQ 0.9176
287 1SQ 0.9174
288 N8Y 0.9172
289 ET2 0.9171
290 CLW 0.9170
291 SHA 0.9169
292 GF4 0.9169
293 DOR 0.9169
294 KTA 0.9169
295 8CM 0.9168
296 15L 0.9168
297 2FY 0.9168
298 BK9 0.9167
299 1M2 0.9167
300 MUA 0.9166
301 AH8 0.9165
302 M4T 0.9165
303 PHU 0.9164
304 8XL 0.9163
305 3XX 0.9163
306 DBX 0.9162
307 M6N 0.9162
308 4RU 0.9162
309 ISN 0.9161
310 4YS 0.9161
311 6FZ 0.9161
312 JBH 0.9160
313 CWJ 0.9160
314 BEA 0.9159
315 36R 0.9158
316 2F6 0.9158
317 FBB 0.9156
318 MR1 0.9156
319 1NP 0.9155
320 N5J 0.9155
321 51R 0.9155
322 FA0 0.9155
323 4TU 0.9154
324 12Q 0.9154
325 94W 0.9154
326 K2T 0.9153
327 5NU 0.9152
328 KBB 0.9150
329 PZI 0.9148
330 PHE 0.9147
331 5SG 0.9146
332 7HQ 0.9146
333 RAT 0.9145
334 JPZ 0.9145
335 PHB 0.9145
336 3Z7 0.9145
337 AJ2 0.9143
338 P72 0.9143
339 091 0.9141
340 82I 0.9140
341 HHA 0.9140
342 G2F 0.9139
343 30G 0.9138
344 AQO 0.9137
345 5JQ 0.9137
346 Q24 0.9136
347 5IQ 0.9136
348 4ZC 0.9136
349 4MU 0.9135
350 FBW 0.9134
351 R8V 0.9134
352 JFJ 0.9133
353 7W4 0.9132
354 O72 0.9132
355 MS9 0.9132
356 PAB 0.9132
357 M2K 0.9131
358 LCN 0.9131
359 15E 0.9131
360 8TX 0.9129
361 1LM 0.9128
362 AZ8 0.9126
363 5QX 0.9126
364 PJW 0.9126
365 MEW 0.9125
366 EVA 0.9125
367 42A 0.9123
368 NOY 0.9123
369 ES1 0.9122
370 6LW 0.9122
371 DIE 0.9122
372 173 0.9120
373 4V2 0.9120
374 9R5 0.9120
375 VGD 0.9120
376 0LH 0.9119
377 NPO 0.9119
378 NGT 0.9118
379 6M9 0.9117
380 M5K 0.9115
381 39O 0.9115
382 5Q0 0.9114
383 4M0 0.9114
384 DEW 0.9113
385 2FG 0.9113
386 2EC 0.9113
387 BHA 0.9112
388 M1Z 0.9112
389 IF7 0.9111
390 IFL 0.9111
391 5CU 0.9108
392 GLA 0.9107
393 ZYR 0.9107
394 5VM 0.9107
395 AJV 0.9104
396 3C4 0.9104
397 3DO 0.9103
398 75K 0.9101
399 N1E 0.9101
400 24W 0.9100
401 1A7 0.9100
402 4JT 0.9100
403 7W1 0.9099
404 X05 0.9099
405 XAZ 0.9098
406 DOB 0.9097
407 DQU 0.9097
408 ISD 0.9095
409 UAN 0.9095
410 3Z8 0.9095
411 6KT 0.9095
412 OMD 0.9095
413 3MG 0.9094
414 EXD 0.9092
415 QPR 0.9092
416 CTL 0.9091
417 6M4 0.9091
418 R1P 0.9090
419 OTD 0.9090
420 CH9 0.9089
421 BTY 0.9088
422 AC6 0.9088
423 F9Y 0.9087
424 XQG 0.9087
425 1P3 0.9087
426 5WY 0.9085
427 C2U 0.9085
428 MQN 0.9083
429 CTS 0.9082
430 Z5P 0.9080
431 TT4 0.9080
432 PE0 0.9079
433 0RW 0.9079
434 UNJ 0.9079
435 GHM 0.9078
436 G3F 0.9076
437 BPY 0.9076
438 GCB 0.9076
439 TTY 0.9075
440 QIC 0.9074
441 KDV 0.9073
442 JP2 0.9071
443 BQ2 0.9071
444 TSS 0.9071
445 MBG 0.9070
446 DE5 0.9069
447 B55 0.9068
448 HQY 0.9068
449 5H1 0.9067
450 EYK 0.9067
451 PXL 0.9067
452 IAC 0.9066
453 3AL 0.9066
454 M5H 0.9065
455 1U6 0.9064
456 A13 0.9064
457 AX3 0.9063
458 TTL 0.9062
459 14O 0.9059
460 PBZ 0.9059
461 1AL 0.9058
462 5MI 0.9056
463 12T 0.9056
464 NID 0.9056
465 IPB 0.9056
466 GLU 0.9056
467 52C 0.9055
468 4JQ 0.9054
469 JTH 0.9052
470 INE 0.9051
471 F60 0.9051
472 GOX 0.9050
473 1Y6 0.9050
474 HJP 0.9049
475 XDK 0.9049
476 TYL 0.9049
477 2ZQ 0.9049
478 X09 0.9049
479 F2W 0.9048
480 259 0.9048
481 2D0 0.9047
482 826 0.9047
483 GUN 0.9046
484 M1A 0.9046
485 AL0 0.9045
486 149 0.9045
487 4BL 0.9044
488 JBK 0.9044
489 ABV 0.9043
490 8S0 0.9043
491 H4E 0.9042
492 2K4 0.9041
493 IWT 0.9041
494 XHP 0.9040
495 7MX 0.9039
496 G5V 0.9038
497 YTX 0.9037
498 4P0 0.9036
499 I6G 0.9036
500 SKF 0.9036
501 JND 0.9036
502 8NX 0.9035
503 GVG 0.9035
504 6AI 0.9034
505 F05 0.9033
506 HBD 0.9031
507 1DW 0.9030
508 5XB 0.9030
509 67N 0.9029
510 5JL 0.9029
511 KW8 0.9029
512 PFL 0.9029
513 TOF 0.9028
514 DRL 0.9028
515 8NB 0.9028
516 2MI 0.9027
517 7B4 0.9027
518 44W 0.9026
519 DIU 0.9026
520 2AK 0.9025
521 5MB 0.9025
522 3QV 0.9025
523 23A 0.9024
524 LGC 0.9024
525 NGO 0.9024
526 FRU 0.9024
527 7ZE 0.9023
528 5WU 0.9023
529 7I2 0.9023
530 ISZ 0.9023
531 H62 0.9022
532 HH8 0.9021
533 X6X 0.9021
534 GCS 0.9021
535 BZX 0.9020
536 0GZ 0.9020
537 APZ 0.9018
538 ZB1 0.9018
539 717 0.9018
540 4XH 0.9017
541 HLD 0.9017
542 FUD 0.9016
543 270 0.9014
544 AX7 0.9014
545 O2A 0.9014
546 F4E 0.9011
547 NDG 0.9010
548 P3K 0.9009
549 WOO 0.9009
550 N3W 0.9008
551 SJ5 0.9008
552 4BY 0.9007
553 4MA 0.9006
554 2H5 0.9006
555 27B 0.9005
556 FH2 0.9004
557 TAG 0.9004
558 N2Z 0.9004
559 2MN 0.9003
560 11S 0.9003
561 KJY 0.9003
562 3ZB 0.9003
563 RIB 0.9003
564 GAF 0.9002
565 SOE 0.9002
566 6QF 0.9001
567 MO8 0.9000
568 5JC 0.9000
569 3FH 0.9000
570 5VL 0.9000
571 0FO 0.9000
572 LZM 0.8999
573 428 0.8995
574 OTW 0.8995
575 4NM 0.8994
576 CFI 0.8994
577 9MG 0.8994
578 HXX 0.8994
579 XDE 0.8993
580 KJH 0.8993
581 RNS 0.8992
582 1KP 0.8991
583 RNT 0.8990
584 FBU 0.8990
585 AN3 0.8990
586 ODO 0.8990
587 6XI 0.8990
588 XXP 0.8989
589 EDR 0.8989
590 TIU 0.8989
591 B62 0.8989
592 MLT 0.8989
593 R9Y 0.8988
594 ADZ 0.8988
595 DHY 0.8987
596 9KT 0.8986
597 OIA 0.8986
598 GXL 0.8986
599 PBA 0.8984
600 9EW 0.8983
601 MNM 0.8983
602 2YU 0.8982
603 K5W 0.8982
604 DFB 0.8982
605 0TU 0.8981
606 SYV 0.8981
607 L22 0.8981
608 M4E 0.8981
609 JB5 0.8980
610 NDH 0.8980
611 LI6 0.8980
612 3HP 0.8980
613 1X7 0.8980
614 1QP 0.8979
615 SWD 0.8977
616 44V 0.8976
617 MCT 0.8976
618 DIG 0.8974
619 6ME 0.8974
620 NCA 0.8973
621 SKA 0.8973
622 J6W 0.8973
623 PAC 0.8971
624 N7I 0.8971
625 FA3 0.8970
626 ES9 0.8968
627 E5X 0.8968
628 C2A 0.8965
629 BSX 0.8964
630 ALL 0.8964
631 ANN 0.8963
632 GZ2 0.8962
633 II6 0.8962
634 4YO 0.8960
635 FAN 0.8960
636 5LA 0.8959
637 IV2 0.8958
638 MJ2 0.8958
639 36E 0.8957
640 4KL 0.8956
641 8XQ 0.8956
642 1L5 0.8956
643 GIV 0.8956
644 TSR 0.8955
645 H4N 0.8955
646 CKA 0.8955
647 CSN 0.8952
648 23J 0.8951
649 LFR 0.8950
650 KBG 0.8950
651 174 0.8949
652 HDH 0.8949
653 BE2 0.8949
654 AS3 0.8949
655 OGA 0.8949
656 XQK 0.8948
657 2CQ 0.8948
658 PBC 0.8948
659 PIM 0.8947
660 ES6 0.8946
661 FDK 0.8946
662 6OT 0.8945
663 PIY 0.8945
664 AOS 0.8944
665 LEL 0.8944
666 FK1 0.8943
667 GNM 0.8943
668 DRG 0.8943
669 QBK 0.8942
670 EGR 0.8942
671 FP1 0.8942
672 DMJ 0.8942
673 HA7 0.8942
674 SRT 0.8941
675 3U4 0.8941
676 HPA 0.8941
677 NCD 0.8941
678 SAL 0.8940
679 FDB 0.8940
680 7VJ 0.8940
681 LYL 0.8940
682 SHG 0.8940
683 TGX 0.8939
684 7ME 0.8939
685 8IG 0.8938
686 9AP 0.8938
687 MWM 0.8937
688 ANF 0.8937
689 VM1 0.8937
690 MVN 0.8936
691 261 0.8936
692 141 0.8935
693 8OZ 0.8935
694 OTR 0.8935
695 OAA 0.8935
696 D07 0.8934
697 XUL 0.8934
698 TH7 0.8933
699 QWN 0.8932
700 FBM 0.8932
701 YIO 0.8932
702 NVU 0.8931
703 MZG 0.8931
704 4CL 0.8931
705 IGA 0.8930
706 E7S 0.8930
707 IFM 0.8930
708 GO2 0.8930
709 MNP 0.8928
710 3BU 0.8928
711 DNA 0.8928
712 1GN 0.8927
713 BEN 0.8927
714 5GT 0.8926
715 293 0.8925
716 ANC 0.8923
717 7MK 0.8923
718 OXZ 0.8921
719 4I8 0.8921
720 P92 0.8921
721 GCO 0.8921
722 XAN 0.8921
723 BEZ 0.8921
724 ADE 0.8920
725 CFF 0.8920
726 5NE 0.8919
727 AA 0.8918
728 2D3 0.8918
729 NAG 0.8918
730 37T 0.8916
731 BPU 0.8916
732 XEN 0.8916
733 HMH 0.8916
734 SXS 0.8915
735 HT4 0.8915
736 PRF 0.8915
737 SAF 0.8915
738 6PC 0.8915
739 LDR 0.8913
740 NIZ 0.8913
741 QY9 0.8913
742 I1E 0.8912
743 XYL 0.8912
744 2CK 0.8912
745 RB5 0.8912
746 263 0.8912
747 AZA 0.8911
748 IOS 0.8911
749 GXY 0.8911
750 Z82 0.8909
751 209 0.8908
752 27Y 0.8907
753 A2F 0.8906
754 XBZ 0.8906
755 TC7 0.8906
756 GLT 0.8906
757 9DG 0.8905
758 4JJ 0.8905
759 GIF 0.8905
760 2AC 0.8905
761 329 0.8905
762 DQA 0.8905
763 4SV 0.8904
764 NPY 0.8903
765 GJS 0.8903
766 61M 0.8903
767 TEP 0.8902
768 REL 0.8902
769 FIX 0.8901
770 GT0 0.8901
771 BHO 0.8901
772 M6Z 0.8901
773 PPY 0.8900
774 XYP 0.8900
775 NBG 0.8900
776 GTL 0.8899
777 JZ2 0.8898
778 4HO 0.8897
779 J9W 0.8897
780 8NY 0.8897
781 PO6 0.8897
782 2HG 0.8897
783 URF 0.8896
784 GLO 0.8895
785 QXW 0.8894
786 0BP 0.8894
787 D3G 0.8894
788 28N 0.8894
789 CXH 0.8893
790 QOS 0.8892
791 8GK 0.8892
792 EV3 0.8892
793 0XT 0.8892
794 QX4 0.8892
795 MWJ 0.8891
796 2XX 0.8890
797 6AP 0.8890
798 QUZ 0.8890
799 948 0.8890
800 YH7 0.8890
801 4ZE 0.8889
802 FHC 0.8889
803 GNL 0.8889
804 7VP 0.8889
805 SG2 0.8889
806 Y8I 0.8888
807 EWG 0.8888
808 MSR 0.8888
809 AMG 0.8888
810 6GU 0.8887
811 AZG 0.8887
812 GM7 0.8887
813 AC0 0.8886
814 NIO 0.8885
815 10L 0.8884
816 BR9 0.8884
817 EV0 0.8883
818 HQ9 0.8883
819 BDF 0.8882
820 PKU 0.8881
821 150 0.8880
822 AKG 0.8880
823 UEG 0.8879
824 XYD 0.8878
825 DYA 0.8878
826 DHR 0.8878
827 F9P 0.8877
828 THA 0.8877
829 JAE 0.8876
830 344 0.8876
831 BNL 0.8876
832 5MH 0.8875
833 HBO 0.8875
834 HDL 0.8874
835 LMR 0.8873
836 PHH 0.8872
837 2A7 0.8872
838 B57 0.8871
839 AHN 0.8871
840 S2G 0.8871
841 XM0 0.8871
842 HSO 0.8870
843 CFP 0.8870
844 TH0 0.8870
845 RJY 0.8870
846 DHQ 0.8870
847 H33 0.8869
848 UFO 0.8869
849 CXF 0.8869
850 H5B 0.8867
851 CIT 0.8866
852 TM7 0.8865
853 X11 0.8865
854 SF9 0.8865
855 3VX 0.8865
856 MXN 0.8865
857 BTE 0.8864
858 A1U 0.8864
859 EMZ 0.8863
860 DYT 0.8862
861 MNN 0.8862
862 SOR 0.8862
863 HHI 0.8862
864 1DJ 0.8861
865 5F5 0.8861
866 RSO 0.8861
867 45C 0.8860
868 S2P 0.8860
869 MAQ 0.8860
870 AGK 0.8859
871 4VY 0.8859
872 DEE 0.8859
873 PA1 0.8859
874 PNZ 0.8859
875 F4Z 0.8858
876 692 0.8858
877 8W9 0.8857
878 SDD 0.8856
879 1XM 0.8855
880 VGL 0.8855
881 VK3 0.8854
882 9DA 0.8852
883 LSA 0.8852
884 34A 0.8851
885 3J8 0.8851
886 2MP 0.8850
887 BIK 0.8850
888 LKA 0.8849
889 32X 0.8847
890 NCT 0.8846
891 I3E 0.8845
892 M3H 0.8845
893 PXM 0.8844
894 FDR 0.8844
895 4VS 0.8844
896 HNQ 0.8844
897 2JK 0.8844
898 3SK 0.8843
899 7HP 0.8842
900 PQ0 0.8842
901 GJZ 0.8842
902 RXA 0.8841
903 FYU 0.8840
904 Q02 0.8839
905 1WG 0.8838
906 R2P 0.8838
907 1WC 0.8838
908 EVF 0.8837
909 6DP 0.8837
910 R8Y 0.8837
911 ZME 0.8836
912 X0U 0.8836
913 BAM 0.8836
914 RMN