Receptor
PDB id Resolution Class Description Source Keywords
5MQK 1.53 Å EC: 2.3.1.48 CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH CBP01 HOMO SAPIENS CREBBP BROMODOMAIN INHIBITOR TRANSCRIPTION
Ref.: VIRTUAL SCREEN TO NMR (VS2NMR): DISCOVERY OF FRAGME FOR THE CBP BROMODOMAIN. BIOORG. MED. CHEM. LETT. V. 27 2472 2017
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
QPR B:1201;
A:1201;
Valid;
Valid;
none;
none;
submit data
173.211 C11 H11 N O CC(=O...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6AY3 1.39 Å EC: 2.3.1.48 CREBBP BROMODOMAIN IN COMPLEX WITH CPD16 (5-(7-(DIFLUOROMETH METHYL-1H-PYRAZOL-4-YL)-3,4-DIHYDROQUINOLIN-1(2H)-YL)-N-METI NDOLE-3-CARBOXAMIDE) HOMO SAPIENS CREBBP BROMODOMAIN TRANSFERASE-TRANSFERASE INHIBITOR COMPL
Ref.: A UNIQUE APPROACH TO DESIGN POTENT AND SELECTIVE CY ADENOSINE MONOPHOSPHATE RESPONSE ELEMENT BINDING PR BINDING PROTEIN (CBP) INHIBITORS. J. MED. CHEM. V. 60 10151 2017
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 64 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
70% Homology Family (42)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 5NLK Kd = 0.035 uM 92E C24 H23 N3 O6 CCOc1ccc(c....
2 5MQE Kd = 4 uM PKU C6 H7 Br N2 O CNC(=O)c1c....
3 4YK0 Kd = 181 uM 098 C24 H29 N3 O5 c1ccc2c(c1....
4 5MPZ Kd = 85 uM 4I8 C9 H7 N O4 COC(=O)c1c....
5 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
6 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
7 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
8 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
9 3P1D - MB3 C5 H9 N O CN1CCCC1=O
10 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
11 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
12 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
13 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
14 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
15 5MQK - QPR C11 H11 N O CC(=O)c1cn....
16 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
17 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
18 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
19 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
20 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
21 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
22 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
23 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
24 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
25 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
26 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
27 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
28 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
29 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
30 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
31 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
32 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
33 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
34 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
35 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
36 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
37 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
38 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
39 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
40 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
41 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
42 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
50% Homology Family (389)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6JJ3 ic50 = 100 nM BS6 C23 H25 N5 O4 S CN1CCN(CC1....
2 6P05 ic50 = 5.9 nM YF2 C30 H28 N6 O3 S CCS(=O)(=O....
3 4IOO - BAE C6 H13 N O CC(C)(C)C(....
4 5I88 Kd = 250 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
5 5DX4 Kd = 0.137 uM E0C C20 H17 Br N2 O4 S CCN1c2ccc(....
6 6JJB ic50 = 49.5 nM BT0 C19 H16 N2 O4 S CN1c2ccc(c....
7 3JVK Kd = 118 uM GLY GLY ALY ALA PRO ARG LYS GLN n/a n/a
8 4HBX ic50 = 1.9 uM 14X C13 H17 N3 O3 S CN1Cc2cc(c....
9 4NUE Ki = 0.15 uM NUE C19 H19 N5 O3 S Cc1cc(c(c(....
10 6SB8 Kd = 0.07 uM L45 C21 H27 N3 O5 S CCN(CC)S(=....
11 5Y94 Kd = 164 nM 8QC C16 H16 Br N3 O4 S Cc1c2cc(c(....
12 6DMJ - 53W C27 H32 N4 O3 Cc1c(c(on1....
13 4HXR ic50 = 4.1 uM 1A4 C13 H10 N2 O3 S3 c1cc(cc(c1....
14 6DML - 9BM C25 H26 N4 O4 Cc1c(c(on1....
15 5TI5 ic50 = 41 uM 7CN C16 H13 Br N2 O3 S c1cc(cc(c1....
16 6VUJ ic50 = 35.2 uM RLY C23 H30 N2 O5 S CCN(CC)S(=....
17 6X7B ic50 = 27 nM ZVP C26 H24 N4 O5 S c1cc(cnc1)....
18 4O7C ic50 = 10 uM 2RK C22 H23 N5 O C1CNCCC1C2....
19 4IOQ - BAQ C4 H7 N O C1CC(=O)NC....
20 4HXK - 1AJ C11 H11 N3 O S c1csc2c1CN....
21 6S6K Kd = 0.18 uM KXK C24 H31 N3 O5 S Cc1c2c(c([....
22 2YEL ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
23 6RWJ Kd = 6.41 uM KLK C12 H16 N2 O2 Cc1c2c(c([....
24 6SA2 Kd = 0.08 uM L25 C22 H27 N3 O6 S Cc1c2c(c([....
25 6XV7 - O2Q C14 H13 F2 N5 Cc1nnc2n1n....
26 4BW4 ic50 = 631 nM 9B6 C22 H16 F3 N5 O4 Cc1c(c(on1....
27 4O72 ic50 = 1 uM 2R4 C25 H19 N O3 S c1ccc2c(c1....
28 5F63 Kd = 12 nM 5W2 C28 H35 Cl F N7 O3 S Cc1cnc(nc1....
29 5HLS ic50 = 0.039 uM 62G C20 H16 Cl N3 O2 Cc1c-2c(on....
30 4HBW ic50 = 4.8 uM 14Z C11 H15 N3 O3 S CCNS(=O)(=....
31 4OGI Kd = 37 nM R78 C28 H39 N7 O3 CC[C@@H]1C....
32 6WW8 - YR0 C31 H32 N6 O4 S CN(C)C(=O)....
33 5TI7 ic50 = 11 uM 7CQ C17 H19 Br N2 O4 S COc1ccc(cc....
34 4J0S ic50 = 0.382 uM 1H3 C18 H17 N O3 Cc1c(c(on1....
35 6Q3Y Kd = 54 nM HG5 C30 H38 N6 O2 CC[C@@H]1C....
36 6SAJ Kd = 0.05 uM L2Z C23 H27 N3 O6 S Cc1c2c(c([....
37 4F3I Kd = 36.1 nM 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
38 4QZS Kd = 89 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
39 6AFR ic50 = 70 nM 9E3 C13 H10 F N3 O c1cc2c(ccc....
40 4WIV Kd = 550 nM 3P2 C21 H23 N5 O Cc1c(c(on1....
41 6VUF ic50 = 147 uM RLV C14 H20 N2 O3 S CCCNS(=O)(....
42 3P5O Kd = 55.2 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
43 4UIX ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
44 4HXS ic50 = 4.1 uM 1A3 C16 H14 N2 O3 S2 c1ccc(cc1)....
45 5HM0 ic50 = 0.44 uM 62V C18 H13 Cl N2 O Cc1c-2c(on....
46 5DLX Kd = 2 uM 5D2 C25 H33 Cl N8 O Cc1nnc2n1n....
47 5TI2 ic50 = 24 uM 7CJ C16 H15 F N2 O3 S c1cc(cc(c1....
48 5D3H Kd = 7.9 uM 57G C20 H27 N3 O6 S CCc1c(c([n....
49 6E4A Kd = 44 nM HRY C29 H34 Cl N7 O CN1C=C(C=C....
50 4MEP ic50 = 4.7 uM 24Y C19 H14 Cl N5 O Cc1cccnc1n....
51 4YH4 ic50 = 26 uM Y81 C20 H15 N3 O2 c1ccc(cc1)....
52 5D3N Kd = 9.2 uM L40 C18 H23 N3 O4 S CCc1c(c([n....
53 6C7R Kd = 2.2 nM EO4 C24 H25 N7 O2 Cc1c(c(on1....
54 6WGX ic50 = 0.15 uM U0D C31 H36 F3 N7 Cc1cc(cc(c....
55 6HOV - FER C10 H10 O4 COc1cc(ccc....
56 5D26 Kd = 0.81 uM L28 C19 H26 N4 O5 S CCc1c(c([n....
57 3MUK Kd = 380 uM ALA THR PRK ALA ALA ARG LYS SER n/a n/a
58 4J3I Kd = 8.93 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
59 6X7D ic50 = 388 nM UT4 C19 H18 N2 O4 S c1cc2c(cc1....
60 4QB3 Kd = 3.4 uM 30M C17 H21 N3 O2 CC(=O)NCCC....
61 4LZS Kd = 16 uM L46 C11 H16 N2 O2 CCc1c(c([n....
62 6HDQ ic50 = 5.01 uM FZE C30 H37 F2 N5 O Cc1cc(cnc1....
63 4O71 ic50 = 18 uM CPB C21 H20 Cl N O5 C[N@]1CC[C....
64 4CFL Kd = 1.33 uM 8DQ C19 H18 N2 O2 c1ccc(cc1)....
65 4C67 - L5S C15 H12 N4 S Cc1nnc2n1-....
66 6V1K - 5SW C20 H23 N3 O3 CN1C=C(c2c....
67 4QR3 ic50 = 1.4 uM BNJ C14 H16 N2 O3 S2 c1cc(cc(c1....
68 4ZC9 - 4MW C38 H37 Cl N8 O7 S Cc1c(sc-2c....
69 4MEO - 25V C18 H16 N2 O2 Cc1cc(c2cc....
70 6UVM Kd = 510 uM QJA C11 H13 N O S2 CC(=O)N1CC....
71 4LRG ic50 = 0.026 uM 1XB C20 H18 Cl N3 O2 S Cc1c(sc-2c....
72 6CKS ic50 = 0.015 uM F5Y C23 H23 N3 O4 S CCS(=O)(=O....
73 6DJC Ki = 232.8 nM CF6 C48 H54 Cl2 N10 O2 S2 Cc1c(sc-2c....
74 5TI3 ic50 = 44 uM 7CG C16 H14 Br2 N2 O3 S c1cc(cc(c1....
75 4HXP - 1A5 C10 H10 N2 O3 c1cc(ccc1C....
76 6PSB ic50 = 24 uM Y18 C17 H19 N3 O2 CN1C[C@H](....
77 6CD4 ic50 = 5.14 uM EX1 C33 H42 N8 O3 CC(C)N1c2c....
78 4O7E ic50 = 5.7 uM 2RN C20 H15 N3 O c1ccc(cc1)....
79 4O74 ic50 = 0.025 uM R78 C28 H39 N7 O3 CC[C@@H]1C....
80 4BW2 ic50 = 6.31 uM UTH C24 H24 N4 O3 Cc1c(c(on1....
81 5CS8 ic50 = 2.29 uM EB8 C21 H18 N2 O5 S CCN1c2ccc(....
82 3U5J Kd = 2.46 uM 08H C17 H13 Cl N4 Cc1nnc2n1-....
83 5EIS Kd = 1.8 uM 5OU C14 H13 Cl N4 O2 CCn1cnc2c1....
84 6FO5 Kd = 0.19 uM DZH C25 H26 N6 O5 S CCn1cnc2c1....
85 6V1L Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
86 3U5L Kd = 0.64 uM 08K C17 H14 Cl N5 Cc1nnc2n1-....
87 4QR4 ic50 = 0.25 uM BNK C14 H15 Cl N2 O3 S2 c1cc(c(cc1....
88 4O7A ic50 = 19 uM 2RF C16 H10 Cl2 N2 O3 c1cc(cc(c1....
89 5F61 Kd = 35 nM 5W0 C26 H34 F N7 O2 S Cc1cnc(nc1....
90 4HXN - 1A7 C9 H6 F N O S c1ccc(c(c1....
91 6DL2 Ki = 33 nM GUJ C17 H17 N3 O S Cc1c(c2c(s....
92 5Z5U - 96U C12 H10 N4 O2 c1cn(cn1)c....
93 5TI4 ic50 = 26 uM 7CM C16 H14 Cl F N2 O3 S c1cc(cc(c1....
94 5Y8C ic50 = 0.16 uM 8P9 C16 H15 Cl N2 O5 S Cc1c2cc(c(....
95 4NUD Ki < 0.0845 uM NUD C18 H17 N5 O3 S Cc1cc(c(cc....
96 4O7B ic50 = 20 uM 2RJ C26 H26 F N5 O Cc1cccc(c1....
97 5CPE ic50 = 0.45 uM EB2 C20 H24 N2 O3 S CCN1c2ccc(....
98 5MLI ic50 = 130 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
99 5DW2 Kd = 1.44 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
100 5D3P Kd = 7.4 uM 57E C19 H21 N3 O4 S CCc1c(c([n....
101 4PCE ic50 = 7 uM 2N0 C17 H19 N O CCc1cc2c(n....
102 5D25 Kd = 0.46 uM 56M C19 H25 N3 O5 S CCN(CC)S(=....
103 5DLZ Kd = 1.8 uM 5D1 C28 H35 N3 O3 Cc1cccc(c1....
104 5Y8W ic50 = 0.23 uM 8PU C15 H13 Br N2 O5 S Cc1c2cc(c(....
105 4J0R ic50 = 0.386 uM 1H2 C18 H17 N O3 Cc1c(c(on1....
106 6MH7 ic50 = 1.3 uM JQY C26 H27 F N6 Cc1ccc(cc1....
107 5F60 Kd = 43 nM 5VZ C26 H34 Cl N7 O2 S Cc1cnc(nc1....
108 5Z5V ic50 = 287 nM 96X C15 H14 N4 O2 CC(=O)Nc1c....
109 4HXO - 1A6 C11 H10 N4 O S Cc1cc(on1)....
110 5CRM ic50 = 1.09 uM EB5 C15 H16 N2 O3 S CCNS(=O)(=....
111 6YQN ic50 = 0.72 uM P8T C32 H28 Cl N7 O2 S Cc1c(sc-2c....
112 5CQT Kd = 0.124 uM EB3 C19 H22 N2 O3 S CCN1c2ccc(....
113 5KHM Ki = 5.012 nM XNH C25 H33 N7 O3 C[C@@H]1C(....
114 6XV3 - O2B C28 H33 N9 O Cc1nnc2n1c....
115 4Z1S ic50 = 0.79 uM 559 C23 H21 Cl N6 Cc1nnc2n1-....
116 4MR3 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
117 5MKZ ic50 = 20 uM RNK C11 H12 Cl N3 O S Cc1ccsc1CN....
118 5ULA Ki = 77 nM 5MJ C20 H19 Cl N2 O3 CC1=C(CCC1....
119 4O78 ic50 = 4.6 uM SAV C21 H22 N6 O3 Cc1c2ccc(c....
120 6XVC - O32 C22 H21 N5 O2 Cc1nnc2n1c....
121 4OGJ Kd = 164 nM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
122 5A85 ic50 = 5.01 uM 78J C21 H30 N4 O2 CC1=Cc2ccn....
123 5TI6 ic50 = 21 uM 7CO C16 H14 F2 N2 O3 S c1cc(cc(c1....
124 6MAU - JBS C30 H32 N6 O3 Cc1c(c(on1....
125 6S4B Kd = 0.14 uM KUH C22 H29 N3 O5 S CCN(CC)S(=....
126 6Q3Z Kd = 44 nM HG8 C29 H38 N6 O2 S CC[C@@H]1C....
127 6V0U Kd = 392 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
128 6VUC ic50 = 144 uM RLS C16 H22 N2 O3 S CN1C[C@H](....
129 4MR4 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
130 4QR5 ic50 = 0.06 uM BNM C18 H21 N3 O4 S2 c1c(cc(cc1....
131 4MEQ - 25O C12 H11 N5 Cc1cc(n2c(....
132 4O77 ic50 = 2.5 uM 2RE C20 H14 F N3 O c1cc(ccc1c....
133 6XUZ - O1W C24 H33 N9 O2 Cc1nnc2n1c....
134 5EI4 ic50 = 26.4 uM 5NV C17 H17 Cl N8 O2 S CCn1c(nc2c....
135 5CY9 Kd = 0.218 uM E0A C17 H20 N2 O3 S CCCCS(=O)(....
136 6MH1 ic50 = 1.7 uM JQP C26 H27 F N6 Cc1cc(cc(c....
137 5CRZ ic50 = 0.45 uM EB7 C19 H14 Cl F N2 O3 S CCN1c2ccc(....
138 5Y93 ic50 = 2.27 uM 8Q9 C23 H27 Br N4 O7 S Cc1c2cc(c(....
139 5AD2 Kd = 63 nM ETU C24 H30 Cl N7 O2 C[C@@H]1C(....
140 4E96 ic50 = 0.22 uM 0NS C16 H17 N3 O4 S CN1Cc2cc(c....
141 5D0C Kd = 2.34 uM E0B C21 H25 N3 O4 S CCN1c2ccc(....
142 4O7F ic50 = 13 uM 2RQ C25 H24 F N5 O2 COc1ccccc1....
143 5CP5 Kd = 1.234 uM EB0 C19 H15 F N2 O3 S CCN1c2ccc(....
144 4CFK Kd = 1.83 uM LY2 C19 H17 N O3 c1ccc(cc1)....
145 5D3R - 57C C23 H31 N3 O4 S CCCc1c(c([....
146 4NUC Ki = 0.91 uM 435 C19 H18 N4 O3 S Cc1cc(cc(c....
147 4HXL ic50 = 2.2 uM 1A9 C22 H25 N3 O4 S3 c1cc(sc1)S....
148 6CIY ic50 = 0.41 uM F3J C34 H42 N8 O3 CN1CCN(CC1....
149 5D3L Kd = 0.88 uM 57F C21 H29 N3 O5 S CCc1c(c([n....
150 4A9L - P9L C14 H19 N3 O4 S CN1Cc2cc(c....
151 4XYA Kd = 1370 nM 43S C13 H8 Br N5 O c1coc2c1cc....
152 4C66 - H4C C17 H16 Cl N4 S CCc1cc2c(s....
153 6UWU ic50 ~ 70 nM QKP C27 H34 N2 O6 Cc1cc(cc(c....
154 4O76 ic50 = 0.13 uM 1M3 C26 H35 N7 O2 S Cc1cnc(nc1....
155 5LJ2 ic50 = 10 uM 6XW C25 H32 N6 O4 S CC1=Cc2c(c....
156 6CD5 - R4L C35 H44 N8 O3 CN1CCN(CC1....
157 5I80 Kd = 62 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
158 4O75 ic50 = 21 uM 2RC C23 H26 F N6 O9 P CC1(C(=O)N....
159 5NNF - PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU n/a n/a
160 3ZYU ic50 = 0.1 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
161 4Z1Q ic50 = 0.015 uM 558 C23 H21 Cl N6 Cc1nnc2n1-....
162 6SA3 Kd = 0.42 uM L2N C23 H30 N4 O5 S Cc1c2c(c([....
163 5IGK Kd = 41.8 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
164 5Y1Y ic50 = 0.98 uM HNQ C9 H6 N2 O3 c1cc2c(ccc....
165 5Z5T - 96R C12 H10 N4 O c1cc2c(cc(....
166 6V1U - QMG C20 H19 N3 O2 Cc1ccc(cc1....
167 5KDH Ki = 0.37 uM 6RX C18 H17 N3 O4 CCN1C2=C([....
168 4PS5 ic50 = 0.29 uM 2TA C27 H36 N6 O3 S Cc1cnc(nc1....
169 5D24 Kd = 5.8 uM L26 C18 H21 N3 O4 CCc1c(c([n....
170 5ACY Kd = 6.4 nM 9S3 C30 H35 N3 O C[C@H]1C[C....
171 5HCL ic50 = 6 mM 5Y9 C4 H9 N O CC(=O)N(C)....
172 5COI ic50 = 2.58 uM 55K C20 H22 N2 O5 S CCN1c2ccc(....
173 6UWX Kd = 290 uM QKD C12 H17 N O2 S2 CCOC(=O)N1....
174 5Y8Y Kd = 82 nM 8PX C16 H15 Br N2 O5 S Cc1c2cc(c(....
175 4HXM ic50 = 0.79 uM 1A8 C17 H17 N3 O4 S3 CCCC(=O)Nc....
176 5F62 Kd = 6.8 nM 5W1 C26 H33 Cl F N7 O2 S Cc1cnc(nc1....
177 5D3S Kd = 1.3 uM 579 C20 H24 F N3 O5 S CCc1c(c([n....
178 6YQP ic50 = 1.35 uM P8N C29 H27 Cl N6 O3 S Cc1c(sc-2c....
179 6AJX Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
180 4LYW Kd = 237 nM 21Q C20 H27 N3 O5 S CCc1c(c([n....
181 4HBV ic50 = 23 uM 15E C9 H9 Br N2 O CN1Cc2cc(c....
182 5LUU Kd = 8.63 uM 77X C15 H17 N3 O CCC(=O)N1C....
183 4YH3 ic50 = 26 uM Y80 C24 H20 N2 O3 COc1ccc(cc....
184 6AJV Kd = 9.1 uM HCC C15 H12 O4 c1cc(ccc1C....
185 6CZV ic50 = 0.23 uM FOY C17 H16 N2 O2 Cc1c(c(on1....
186 4X2I ic50 = 0.35 uM 3X0 C18 H17 Cl N4 Cc1nnc2n1-....
187 6CJ1 ic50 = 6.31 uM FND C34 H44 N8 O3 CC[C@H](C)....
188 5F5Z Kd = 86 nM 5VY C26 H35 N7 O2 S Cc1cnc(nc1....
189 6UVJ Kd = 20 uM QJ1 C11 H15 N O2 S2 COC(=O)N1C....
190 6FNX ic50 = 12.6 uM DYZ C14 H14 N4 O2 CCn1cnc2c1....
191 4HBY ic50 = 4.4 uM 13F C15 H15 N3 O3 S CN1Cc2cc(c....
192 5D3J Kd = 5.7 uM L33 C20 H27 N3 O4 S CCc1c(c([n....
193 6AJY Kd = 5.3 uM A0R C16 H14 O4 COc1ccccc1....
194 3MUL - GLY GLY BTK ALA PRO ARG LYS GLN n/a n/a
195 4LR6 ic50 = 33 uM 1XA C10 H10 N2 O Cc1c(c(on1....
196 5AD3 Kd = 7.9 nM K6K C26 H30 N10 O3 CN(CCOc1cc....
197 4PCI ic50 = 7.5 uM 2NJ C16 H16 N2 O CN1c2ccccc....
198 5D3T Kd = 12 uM 56Y C19 H23 N3 O3 CCc1c(c([n....
199 6SAH Kd = 0.26 uM L2W C23 H29 N3 O5 S Cc1c2c(c([....
200 5LJ1 ic50 > 0.0000316 M 6XX C28 H35 F2 N5 O3 Cc1cc(cnc1....
201 4O70 ic50 = 19 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
202 4XY9 Kd = 4651 nM 43U C12 H10 Br N5 O COc1ccc(cc....
203 3MXF - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
204 5CFW Kd = 0.78 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
205 5A5S ic50 = 1.3 uM NP8 C20 H23 N5 O2 CC1=Cc2c(c....
206 4UIY ic50 = 0.00000001 M 5V2 C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
207 6PS9 ic50 = 79 uM Y17 C18 H21 N3 O2 CN1C[C@@H]....
208 4LZR Kd = 20 uM LOC C22 H25 N O6 CC(=O)N[C@....
209 6PRT ic50 = 2120 uM OWA C8 H13 N O3 CN1C[C@H](....
210 4BW1 ic50 = 1.26 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
211 6YQO ic50 = 4.53 uM P8Q C33 H36 Cl N7 O4 S Cc1c(sc-2c....
212 4MEN - 25K C15 H17 N5 Cc1ccc(cc1....
213 6CIS ic50 = 0.3 uM X26 C37 H48 N8 O3 CC(C)Oc1cc....
214 6CKR ic50 = 0.05 uM F5V C21 H20 N4 O3 S Cn1cc(cn1)....
215 4UIZ ic50 = 0.00001995 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
216 5KJ0 ic50 = 130 nM 6TB C29 H41 N7 O3 CC[C@@H]1C....
217 4KV1 - THR PHE ALY SER ILE MET LYS n/a n/a
218 5EGU Kd = 1.4 uM 5NQ C23 H32 N8 O2 S CCCCc1c(nc....
219 5Y8Z ic50 = 0.62 uM 8Q3 C16 H15 Br N2 O4 S Cc1cc2c(cc....
220 6VUB ic50 = 629 uM RLG C11 H13 N O CN1C[C@H](....
221 4BW3 ic50 = 501 nM 9BM C25 H26 N4 O4 Cc1c(c(on1....
222 3U5K - 08J C18 H13 Cl F N3 Cc1ncc2n1-....
223 6FGH - 6RZ C10 H16 N2 O2 S Cc1c(cccn1....
224 6FG6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
225 6FGG Kd = 17 uM D9B C18 H20 N4 O4 CN1C=C(C=C....
226 5MGJ Kd = 51 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
227 6FGV - D9T C14 H21 N3 O2 CN1C=C(C=C....
228 6FGL ic50 = 24 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
229 5OR8 - JR4 C17 H18 F N3 O3 S Cc1cc2c(cc....
230 5FE0 - ALY C8 H16 N2 O3 CC(=O)NCCC....
231 5LVR Kd = 250 uM 78Y C10 H10 N4 O Cc1c(nn(n1....
232 5FDZ Kd = 6.8 uM 5X0 C21 H24 N2 O5 CNC(=O)c1c....
233 5FE1 - 12Q C10 H9 N O CN1c2ccccc....
234 5FE6 Kd = 6910 uM 5WZ C9 H16 N2 O C1CC1C(=O)....
235 5FE2 - 5WV C9 H9 N O CN1Cc2cccc....
236 5FE7 Kd = 488 uM 5WU C10 H14 N2 O2 Cc1c2c(n(n....
237 5FE8 - 5WT C13 H14 N2 O2 CC1=CC(=O)....
238 5FE4 - 5WY C9 H9 N O3 c1cc(c2c(c....
239 5FE9 Kd = 20.98 uM 5WS C12 H14 N2 O3 S CC1=CC(=O)....
240 5FE5 - 2QC C9 H9 N3 S c1cc(ccc1C....
241 5MKX ic50 = 20 uM 82I C6 H8 Cl N3 O CNC1=C(C(=....
242 5LVQ Kd = 73 uM 2LX C13 H17 N O3 CNC(=O)c1c....
243 5FE3 - 5WX C8 H8 N2 O2 COc1cccc2c....
244 6C7Q - EO1 C25 H23 N7 O2 Cc1c(c(on1....
245 2YEM ic50 = 15.5 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
246 5JWM ic50 = 3.09 nM 6ON C54 H66 Cl2 N10 O9 S2 Cc1c(sc-2c....
247 5UOO Ki = 1.4 nM 8FV C26 H21 N5 O2 Cc1c(c(on1....
248 3QZS Kd = 99 uM LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
249 3QZT - LYS GLY GLY ALA ALY ARG HIS ARG LYS VAL n/a n/a
250 5U6V ic50 = 21 nM 7WY C22 H19 Cl N6 Cc1c-2n(nn....
251 5O3A - 31P C23 H23 Cl N4 O3 CC[C@H]([C....
252 5DFD - 59E C23 H21 N5 O3 Cc1nnc2n1-....
253 5XHK - LDR C13 H9 N O c1ccc2c(c1....
254 5O3D - 9J5 C23 H23 Cl N4 O3 CC[C@H]([C....
255 6YTM Kd = 65 nM PMW C22 H25 Cl N4 O2 S CC[C@H]([C....
256 6VIY Ki = 1.1 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
257 5IG6 Kd = 213.7 uM 6B3 C27 H18 N2 O4 c1ccc2c(c1....
258 5O3G - 9J8 C25 H26 Cl N5 O2 CCNC(=O)[C....
259 4J1P Kd = 0.206 uM 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
260 5O3I - 9HN C27 H29 Cl N4 O3 Cc1nnc2n1-....
261 5UEW - 87D C20 H20 N2 O5 S CN1C=C(C(=....
262 5O3B - 9HZ C24 H23 Cl N4 O3 Cc1nnc2n1-....
263 5O3E - 9HW C23 H24 Cl N5 O2 CCNC(=O)[C....
264 3ONI - JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
265 6K04 Ki = 3.1 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
266 5O39 - 31O C22 H21 Cl N4 O3 Cc1nnc2n1-....
267 5O3H - 9HQ C23 H24 Cl N5 O2 CCNC(=O)[C....
268 5O3C - 9J2 C22 H21 Cl N4 O3 Cc1nnc2n1-....
269 4MR6 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
270 6MOA Kd = 2.5 nM JW4 C25 H22 N4 O Cc1ccc2c(c....
271 5DW1 ic50 = 0.08 uM 5GD C24 H29 N3 O4 Cc1cc(cc(c....
272 5DFC - EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
273 4MR5 - 1K0 C20 H22 N2 O5 Cc1cc(cc(c....
274 5O3F - 9HT C24 H26 Cl N5 O2 CC[C@H]([C....
275 2WP1 - LYS ALA PRO ARG ALY GLN LEU ALA THR LYS n/a n/a
276 4FLP Kd = 190.1 nM JQ1 C23 H26 Cl N4 O2 S Cc1c(sc-2c....
277 4KCX Kd = 37 uM 1QK C21 H29 N6 O2 CCc1cnn2c1....
278 4A9I - P9I C15 H13 N2 O C/C(=C/1C=....
279 4UYH ic50 = 0.00000001 M 9S3 C30 H35 N3 O C[C@H]1C[C....
280 4A9H - TVP C12 H15 N O C[C@H]1CCc....
281 4A9F - MB3 C5 H9 N O CN1CCCC1=O
282 4ALG ic50 = 0.5 uM 1GH C23 H21 N5 O3 Cc1c(c(on1....
283 2YEK ic50 = 32.5 nM EAM C22 H22 Cl N5 O2 CCNC(=O)C[....
284 2YDW Kd = 46 nM WSH C25 H21 N5 O2 Cc1nnc2n1-....
285 4A9J - TYL C8 H9 N O2 CC(=O)Nc1c....
286 4A9M ic50 = 0.5 uM P9M C17 H22 N2 O3 S Cc1ccc(cc1....
287 4ALH - A9P C11 H11 N O Cc1c(c(on1....
288 4A9E - 3PF C9 H10 N2 O CN1Cc2cccc....
289 4A9O - A9O C12 H13 N O CCc1c(c(no....
290 4AKN ic50 = 0.79 uM S5B C25 H25 N3 O3 Cc1c(c(on1....
291 4A9N ic50 = 1.5 uM A9N C15 H16 N2 O3 S Cc1ccc(cc1....
292 4KV4 - THR PHE ALY SER ILE MET LYS n/a n/a
293 5UEZ Ki = 970 nM 89G C18 H16 N2 O3 CN1C(=O)C=....
294 6VIX Ki = 1.3 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
295 5UF0 Ki = 160 uM 89J C12 H13 N3 O CNC1=CC(=O....
296 5UEU - 0S6 C20 H19 Cl N4 O2 S Cc1c(sc-2c....
297 4Z93 Kd = 44.6 nM 4LD C24 H23 N5 O2 Cc1c(c(n[n....
298 5UEY Ki = 5.1 nM 88M C22 H24 F2 N2 O5 S CCOC1=CC(=....
299 5UEX Ki = 1.5 nM 89D C24 H26 F2 N2 O5 S CCS(Nc1ccc....
300 5I8B ic50 = 0.11 uM 69F C23 H22 N2 O2 C[C@@H]1CC....
301 5I8G Kd = 0.03 uM 69E C22 H22 N6 O C[C@@H]1CC....
302 5N18 Kd = 2.1 uM 8HZ C21 H19 N3 O Cc1ccc(cc1....
303 5MLJ Ki = 1.4 nM 9ST C17 H21 Br N4 O CN1C[C@H](....
304 6J3P Kd = 105 nM B8O C21 H25 N5 O3 CN1C[C@H](....
305 6AXQ ic50 = 99000 nM C2Y C10 H9 N O2 COC(=O)c1c....
306 5DBM Kd = 0.35 uM 58N C17 H22 N4 O C[C@@H]1CC....
307 5LPM Kd = 2.77 uM 71Y C20 H23 Cl N2 O3 CCc1c(c([n....
308 5NRW - 96N C21 H22 N2 O2 CCc1c(c([n....
309 3P1D - MB3 C5 H9 N O CN1CCCC1=O
310 5LPJ Kd = 10.1 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
311 6FQO ic50 = 0.14 uM E2T C26 H24 N2 O6 CCOc1ccc(c....
312 4TQN Kd = 0.77 uM UL4 C18 H17 N O5 CCOc1ccc(c....
313 6FRF ic50 = 0.04 uM E3T C26 H24 N2 O5 CCOc1ccc(c....
314 5TB6 Kd = 1.53 uM 77X C15 H17 N3 O CCC(=O)N1C....
315 5MQK - QPR C11 H11 N O CC(=O)c1cn....
316 5MQG - F31 C9 H11 N O2 CC(=O)c1cc....
317 5I83 ic50 = 4.1 uM 68Y C18 H20 N2 O2 C[C@@H]1CC....
318 4A9K - TYL C8 H9 N O2 CC(=O)Nc1c....
319 5I86 ic50 = 0.53 uM 69A C18 H19 N3 O2 C[C@@H]1CC....
320 6FR0 ic50 = 0.146 uM E3H C27 H26 N2 O6 CCN1C(=O)C....
321 5NU5 Kd = 0.47 uM 99E C21 H22 N2 O4 CCc1c(c([n....
322 5LPK Kd = 3.06 uM XDM C17 H19 Cl N2 O2 CCc1c(c([n....
323 5MME Kd = 1.4 uM 8Q6 C20 H21 N O6 CCOc1ccc(c....
324 5I89 ic50 = 0.033 uM 69B C21 H22 N4 O C[C@@H]1CC....
325 5NU3 Kd = 0.23 uM 99E C21 H22 N2 O4 CCc1c(c([n....
326 5OWK - 7MX C9 H10 Cl N O3 CCOC(=O)C1....
327 6AY5 ic50 = 69 nM C3V C22 H20 F2 N4 O S Cn1cc(cn1)....
328 5LPL Kd = 12 uM 71X C20 H23 Cl N2 O3 CCc1c(c([n....
329 6FQU ic50 = 2.2 uM E3B C21 H23 F2 N O2 CCOc1ccc(c....
330 6DMK - 2LL C26 H30 N4 O2 Cc1c(c(on1....
331 5MMG Kd = 0.97 uM UT0 C19 H20 N2 O4 S CCOc1ccc(c....
332 5MPN Kd = 0.085 uM YE5 C17 H16 N4 O2 CCOc1ccc(c....
333 5J0D Kd = 134 nM 6F9 C27 H35 N3 O5 CCC(=O)N1C....
334 6AY3 ic50 = 9.5 nM C3J C24 H23 F2 N5 O CNC(=O)c1c....
335 5MPK Kd = 0.003 uM 0BC C21 H18 N6 O3 S CCOc1ccc(c....
336 5CGP Kd = 0.12 uM 53W C27 H32 N4 O3 Cc1c(c(on1....
337 4BJX ic50 = 22 nM 73B C25 H23 Cl N2 O3 C[C@H]1C[C....
338 4UYD ic50 = 79.4 uM V1T C10 H11 N3 O2 CN1c2ccc(c....
339 4XUB ic50 = 1.07 uM 43D C19 H18 N8 Cc1cn(nn1)....
340 4XUA ic50 = 26 uM 43C C21 H18 N6 Cc1cn(nn1)....
341 5MGF Kd = 54 uM 7MW C9 H11 N O3 CCC(=O)c1c....
342 5E9I - F60 C8 H7 N O c1cc(cc2c1....
343 6FGT - D9T C14 H21 N3 O2 CN1C=C(C=C....
344 4NRB ic50 = 38 uM 2LX C13 H17 N O3 CNC(=O)c1c....
345 6FH6 - D8Q C9 H13 N3 O2 CN1C=C(C=C....
346 5MGG - 7MU C7 H7 Cl N2 O CNC(=O)c1c....
347 5ORB - JR6 C16 H19 N3 O2 S Cn1c(c2c(n....
348 4NRC ic50 = 241 uM 2LY C8 H9 N O3 S CNC(=O)c1c....
349 6FH7 - EN2 C17 H18 F N3 O3 CN1C=C(C=C....
350 5E9K - 5KX C3 H3 Cl N2 c1cnc([nH]....
351 4NRA Kd = 65 uM 2LW C13 H13 Cl N2 O CC(=O)N1CC....
352 5MGE Kd = 87 uM 7MX C9 H10 Cl N O3 CCOC(=O)C1....
353 4NR9 - ALY C8 H16 N2 O3 CC(=O)NCCC....
354 5E9L - 6AI C7 H7 N3 c1cc2cn[nH....
355 5OR9 ic50 = 88 uM JR5 C18 H21 F N4 O3 S Cn1c(c2c(n....
356 5E74 Kd = 39 uM 5KH C25 H19 F3 N2 O3 Cc1ccc(cc1....
357 5E9M - BAE C6 H13 N O CC(C)(C)C(....
358 6FGU - D9Q C13 H19 N3 O2 CN1C=C(C=C....
359 5DYX - ADE C5 H5 N5 c1[nH]c2c(....
360 5DYU - MZ0 C4 H6 N2 O c1c([nH]cn....
361 5E73 Kd = 23 uM UO1 C19 H18 N2 O3 Cc1ccc(cc1....
362 7K6R - 9ST C17 H21 Br N4 O CN1C[C@H](....
363 7KDW - WCV C20 H21 N5 O C#CCNc1ncc....
364 7KDZ - WCS C22 H30 N6 O3 S CN(C)CCCOc....
365 7K6S - VYM C13 H16 N2 O c1cc2c(cc1....
366 5A7C ic50 = 0.00018 M 5D4 C10 H20 N2 O2 CC(=O)NCCC....
367 5TPX Kd = 280 nM 7H7 C21 H24 N6 Cc1nnc2n1n....
368 6MO8 - JWD C19 H17 N3 O2 Cc1c(c(on1....
369 6ONY - HWV C28 H30 F N3 O4 CCNC(=O)c1....
370 6JKE - BUX C13 H6 Cl2 N2 O4 c1cc(cc(c1....
371 6MO7 - JWA C19 H25 N3 O4 S Cc1ccc(cc1....
372 6MO9 - JVY C19 H21 N3 O3 S Cc1c(c(on1....
373 3AQA - BYH C17 H16 N4 S2 CN1c2ccccc....
374 6K05 Ki = 95.5 nM CQF C22 H21 Cl N6 Cc1nnc2n1-....
375 5WUU ic50 = 0.81 uM 7UU C18 H18 N2 O3 S CN(CCCNC1=....
376 5N17 Kd = 4.8 uM 8FK C19 H18 N2 O3 S CN1c2ccc(c....
377 5N16 Kd = 5 uM 8FN C22 H15 N5 O2 S c1ccc2c(c1....
378 6VIZ Ki = 120 nM QYY C27 H29 N3 O5 S CCNC(=O)c1....
379 6VIW Ki = 21.6 nM QYV C24 H21 F2 N3 O5 S CCNC(=O)c1....
380 5XXH ic50 = 6.8 uM E0D C18 H20 N2 O4 CC(=O)c1cn....
381 5ML0 - P2L C11 H17 Cl N4 O CN1CCC[C@H....
382 5W0L ic50 = 1.1 nM 9UD C27 H32 F2 N6 O2 CC(=O)N1CC....
383 5W0F ic50 = 16 nM 9U7 C25 H30 N6 O2 CC(=O)N1CC....
384 5W0E ic50 = 0.94 nM 9U4 C27 H33 F2 N7 O2 CNC(=O)N1C....
385 5W0Q ic50 = 18 uM 9UG C12 H16 N2 O2 Cc1ccc2c(c....
386 5W0I ic50 = 1.4 nM 9UA C26 H30 F2 N6 O2 CC(=O)N1CC....
387 5VOM ic50 = 0.79 uM 9GY C24 H23 N3 O4 C[C@H]1CN(....
388 2RI7 - ALA ARG THR MLY GLN THR ALA ARG LYS n/a n/a
389 6J3O Kd = 2.4 uM B4L C13 H19 N5 O CN1CCC[C@H....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: QPR; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 QPR 1 1
2 8M5 0.528302 0.702703
Similar Ligands (3D)
Ligand no: 1; Ligand: QPR; Similar ligands found: 986
No: Ligand Similarity coefficient
1 5WY 0.9815
2 ICO 0.9757
3 5RN 0.9740
4 Q6T 0.9730
5 2ZQ 0.9725
6 BGC 0.9722
7 7NI 0.9712
8 7ZE 0.9699
9 AKH 0.9673
10 4ME 0.9668
11 KYA 0.9667
12 42C 0.9661
13 NID 0.9642
14 M2K 0.9616
15 HLD 0.9614
16 PDC 0.9608
17 DNC 0.9608
18 HNQ 0.9591
19 GLC 0.9575
20 VK3 0.9568
21 RXA 0.9564
22 NQ 0.9563
23 HJP 0.9551
24 92P 0.9538
25 INE 0.9534
26 FOT 0.9534
27 M0Q 0.9527
28 5NE 0.9527
29 BDP 0.9524
30 C2Y 0.9520
31 6VD 0.9519
32 8XQ 0.9517
33 7VS 0.9513
34 M0W 0.9513
35 0GZ 0.9508
36 I3A 0.9503
37 92K 0.9499
38 2LY 0.9496
39 9DG 0.9496
40 LDR 0.9489
41 X8D 0.9488
42 TTY 0.9488
43 4KL 0.9483
44 M5K 0.9482
45 UAN 0.9481
46 GDE 0.9478
47 15L 0.9471
48 PYQ 0.9470
49 G3F 0.9468
50 M1H 0.9465
51 4HC 0.9464
52 UNC 0.9460
53 7WR 0.9460
54 XAN 0.9459
55 Z5P 0.9457
56 M1E 0.9457
57 FBG 0.9456
58 EA1 0.9455
59 GUN 0.9452
60 F12 0.9452
61 DHK 0.9451
62 DNF 0.9450
63 ZZ8 0.9446
64 9AP 0.9445
65 7HQ 0.9444
66 GCU 0.9442
67 D07 0.9441
68 IJZ 0.9439
69 M1Q 0.9438
70 XQG 0.9430
71 PE0 0.9428
72 BTY 0.9427
73 Q24 0.9427
74 12B 0.9426
75 6BL 0.9425
76 C2U 0.9424
77 8S0 0.9424
78 9MG 0.9419
79 J9W 0.9418
80 8GK 0.9415
81 6AP 0.9413
82 MHK 0.9413
83 EVA 0.9413
84 AJ2 0.9409
85 141 0.9407
86 AQO 0.9407
87 3IT 0.9406
88 HLZ 0.9406
89 OTD 0.9406
90 OXC 0.9405
91 AZ8 0.9405
92 GTR 0.9404
93 5RO 0.9404
94 URC 0.9404
95 6GU 0.9403
96 XAZ 0.9401
97 ORO 0.9401
98 A2F 0.9398
99 AIN 0.9398
100 QSH 0.9394
101 MUA 0.9393
102 M6N 0.9393
103 NVU 0.9391
104 FE DB1 0.9390
105 37T 0.9389
106 AZA 0.9389
107 MEW 0.9387
108 APZ 0.9385
109 DX4 0.9382
110 JKZ 0.9380
111 5WX 0.9380
112 IGA 0.9379
113 JR2 0.9379
114 PEY 0.9374
115 GAL 0.9373
116 495 0.9372
117 GCS 0.9371
118 1XM 0.9370
119 2AL 0.9366
120 AZG 0.9365
121 PD2 0.9364
122 HH5 0.9364
123 290 0.9363
124 MT0 0.9362
125 B55 0.9360
126 4TU 0.9360
127 HZQ 0.9357
128 75K 0.9356
129 YH7 0.9356
130 8TX 0.9353
131 AW5 0.9351
132 42A 0.9349
133 LZM 0.9349
134 2AK 0.9347
135 3HA 0.9347
136 23J 0.9342
137 GV9 0.9341
138 AZ9 0.9339
139 FGZ 0.9338
140 D1X 0.9336
141 KIB 0.9333
142 GCB 0.9332
143 HQD 0.9331
144 DBJ 0.9330
145 BK9 0.9330
146 5NS 0.9330
147 34D 0.9323
148 PQK 0.9321
149 O2A 0.9321
150 TSS 0.9320
151 M4E 0.9319
152 DBH 0.9317
153 0CU 0.9316
154 BOA 0.9316
155 RM1 0.9313
156 3F0 0.9312
157 JBK 0.9307
158 MO8 0.9305
159 FDB 0.9305
160 2D0 0.9300
161 GTQ 0.9300
162 5RG 0.9300
163 CFP 0.9297
164 0N7 0.9297
165 5JQ 0.9295
166 DOR 0.9289
167 1XN 0.9286
168 44W 0.9286
169 4MU 0.9282
170 NTZ 0.9281
171 OTW 0.9281
172 YSO 0.9279
173 0FO 0.9275
174 XHP 0.9274
175 DIU 0.9274
176 DQU 0.9270
177 BCP 0.9267
178 1X7 0.9266
179 8IG 0.9265
180 5OB 0.9261
181 3M0 0.9258
182 3MB 0.9257
183 8G0 0.9255
184 KT7 0.9255
185 DRL 0.9254
186 5JL 0.9252
187 OVM 0.9249
188 5M0 0.9248
189 67X 0.9247
190 97T 0.9246
191 PFB 0.9246
192 IAC 0.9245
193 SYA 0.9244
194 0P6 0.9244
195 ARP 0.9243
196 9KT 0.9240
197 G1O 0.9240
198 LSA 0.9240
199 0HO 0.9236
200 MVN 0.9235
201 28N 0.9234
202 PRZ 0.9234
203 G5V 0.9234
204 3MA 0.9233
205 KFH 0.9232
206 TTL 0.9232
207 M5N 0.9229
208 J9Q 0.9227
209 FA0 0.9227
210 DNA 0.9227
211 TEP 0.9226
212 7W1 0.9226
213 HQT 0.9225
214 B62 0.9221
215 9FL 0.9221
216 LGC 0.9221
217 HHA 0.9220
218 8HC 0.9219
219 E7Z 0.9217
220 JUG 0.9215
221 LZ2 0.9215
222 QX4 0.9214
223 6NT 0.9214
224 QBK 0.9212
225 3NY 0.9211
226 0W8 0.9210
227 CFF 0.9206
228 680 0.9205
229 TWO 0.9202
230 0F9 0.9202
231 2FG 0.9202
232 5CU 0.9201
233 12Q 0.9201
234 44V 0.9200
235 X09 0.9200
236 1F1 0.9199
237 6XI 0.9199
238 8CM 0.9198
239 39A 0.9198
240 5WU 0.9196
241 BPU 0.9195
242 6CS 0.9195
243 HQY 0.9194
244 209 0.9194
245 VNL 0.9194
246 2ZM 0.9194
247 NLA 0.9193
248 6ME 0.9193
249 5QX 0.9192
250 5SG 0.9190
251 LI6 0.9190
252 B57 0.9189
253 2KA 0.9188
254 3MG 0.9188
255 G6D 0.9187
256 TOF 0.9185
257 ES0 0.9184
258 M1A 0.9184
259 54G 0.9181
260 KJY 0.9180
261 SRO 0.9180
262 KJH 0.9179
263 2FQ 0.9179
264 4XS 0.9178
265 CWM 0.9178
266 5IQ 0.9177
267 2HU 0.9177
268 FLV 0.9177
269 2A7 0.9176
270 0JD 0.9176
271 ADK 0.9175
272 IPZ 0.9174
273 N5J 0.9174
274 CWS 0.9173
275 DIE 0.9169
276 5NU 0.9168
277 KIA 0.9166
278 149 0.9165
279 4Z4 0.9165
280 4XV 0.9165
281 H33 0.9165
282 0HN 0.9164
283 KUF 0.9164
284 H5B 0.9164
285 CKA 0.9161
286 15N 0.9160
287 091 0.9159
288 BE2 0.9159
289 DOB 0.9157
290 1SQ 0.9156
291 SKA 0.9155
292 7CT 0.9155
293 ES1 0.9154
294 BZ3 0.9153
295 I6G 0.9153
296 SKM 0.9152
297 JPZ 0.9150
298 OMD 0.9150
299 BEA 0.9148
300 8WO 0.9147
301 5NI 0.9147
302 9TZ 0.9147
303 JTH 0.9146
304 CLZ 0.9144
305 261 0.9144
306 UEG 0.9143
307 II6 0.9143
308 HA5 0.9143
309 226 0.9143
310 JBQ 0.9143
311 1LQ 0.9141
312 4YS 0.9141
313 B60 0.9141
314 ODO 0.9141
315 UFV 0.9139
316 NTM 0.9138
317 TQU 0.9136
318 PHT 0.9136
319 3A9 0.9135
320 S76 0.9135
321 GAB 0.9135
322 ABI 0.9134
323 JAW 0.9134
324 4M0 0.9133
325 PX7 0.9130
326 BHA 0.9130
327 PXL 0.9130
328 5Q0 0.9129
329 4CS 0.9129
330 NOJ 0.9129
331 GLA 0.9128
332 M5H 0.9128
333 25W 0.9126
334 SAL 0.9126
335 B53 0.9126
336 1QP 0.9125
337 QX2 0.9123
338 4XH 0.9122
339 M6Z 0.9121
340 0LH 0.9118
341 MS9 0.9118
342 8WZ 0.9116
343 Q88 0.9114
344 E1T 0.9113
345 SHG 0.9113
346 SHA 0.9112
347 MAQ 0.9111
348 3NT 0.9110
349 1NP 0.9110
350 A7W 0.9107
351 NNO 0.9107
352 6NI 0.9107
353 INO 0.9105
354 24W 0.9100
355 UFO 0.9100
356 64C 0.9099
357 67N 0.9098
358 APS 0.9098
359 582 0.9094
360 30G 0.9094
361 NDM 0.9093
362 F31 0.9092
363 2SX 0.9088
364 ZYR 0.9088
365 4NC 0.9088
366 HH8 0.9087
367 9CA 0.9087
368 DIN 0.9083
369 FP1 0.9083
370 8XL 0.9082
371 PHH 0.9082
372 3AB 0.9080
373 5MK 0.9080
374 EV0 0.9079
375 5HN 0.9078
376 4AA 0.9077
377 K17 0.9077
378 BTE 0.9075
379 3HB 0.9075
380 5XC 0.9075
381 MRW 0.9074
382 IV2 0.9074
383 FHB 0.9074
384 GJS 0.9073
385 DHB 0.9073
386 MBG 0.9073
387 GM7 0.9071
388 GIO 0.9070
389 A13 0.9069
390 IOS 0.9069
391 ADA 0.9069
392 8ZE 0.9068
393 329 0.9067
394 FBU 0.9066
395 KLW 0.9065
396 GOG 0.9064
397 JBE 0.9062
398 61M 0.9062
399 P9P 0.9059
400 2H5 0.9059
401 FYU 0.9059
402 5VJ 0.9058
403 COU 0.9058
404 OW7 0.9058
405 4SV 0.9057
406 MYJ 0.9055
407 ONR 0.9054
408 7B3 0.9053
409 1LM 0.9052
410 AS3 0.9051
411 ES6 0.9050
412 OVV 0.9049
413 3U4 0.9048
414 93K 0.9048
415 1IT 0.9046
416 4FS 0.9046
417 692 0.9045
418 SVN 0.9044
419 K5W 0.9044
420 4A3 0.9043
421 5OF 0.9042
422 QWW 0.9041
423 52C 0.9041
424 AA 0.9040
425 JLZ 0.9040
426 TBS 0.9040
427 QAS 0.9038
428 7I2 0.9036
429 39O 0.9035
430 L7T 0.9035
431 SYR 0.9034
432 CHB 0.9033
433 JBH 0.9033
434 XX2 0.9033
435 R8V 0.9032
436 03V 0.9031
437 3DM 0.9030
438 ZVO 0.9027
439 ADE 0.9026
440 DPZ 0.9025
441 2HO 0.9025
442 3WA 0.9024
443 2FY 0.9023
444 GZ8 0.9022
445 8GC 0.9022
446 H42 0.9021
447 ZZ3 0.9020
448 5WV 0.9020
449 FLC 0.9019
450 OCH 0.9018
451 GYE 0.9017
452 1AL 0.9017
453 GZL 0.9017
454 0FK 0.9016
455 BNT 0.9016
456 V55 0.9014
457 JKE 0.9013
458 SX1 0.9012
459 1GN 0.9012
460 NMJ 0.9011
461 OW4 0.9010
462 NCD 0.9008
463 60Q 0.9007
464 JDN 0.9005
465 2EC 0.9004
466 3AL 0.9004
467 AJV 0.9003
468 O72 0.9002
469 QMS 0.9002
470 F0J 0.9000
471 QAT 0.8999
472 3HM 0.8997
473 JB8 0.8996
474 9ZE 0.8995
475 23A 0.8994
476 54X 0.8993
477 MR1 0.8992
478 PRF 0.8992
479 9TW 0.8992
480 IBM 0.8991
481 SOR 0.8991
482 TSR 0.8990
483 2AQ 0.8989
484 WCE 0.8989
485 QSB 0.8987
486 OA3 0.8987
487 HPA 0.8987
488 KGK 0.8983
489 T6C 0.8983
490 6R8 0.8983
491 JB5 0.8982
492 K22 0.8980
493 MJ2 0.8979
494 PQ0 0.8979
495 CIT 0.8978
496 GIV 0.8977
497 53C 0.8974
498 7WV 0.8974
499 XYP 0.8973
500 C9E 0.8973
501 7B4 0.8973
502 86J 0.8973
503 ES5 0.8972
504 7HP 0.8972
505 BZX 0.8972
506 JIF 0.8970
507 R8S 0.8970
508 FA3 0.8970
509 KBB 0.8969
510 GTL 0.8968
511 J9T 0.8967
512 MVL 0.8967
513 MQB 0.8967
514 7ME 0.8966
515 0RW 0.8966
516 LT8 0.8966
517 N8Y 0.8966
518 K32 0.8965
519 6DP 0.8964
520 KBG 0.8963
521 HMU 0.8963
522 MT8 0.8961
523 3Z8 0.8960
524 PFL 0.8959
525 7MX 0.8959
526 CTS 0.8959
527 9HX 0.8959
528 10L 0.8958
529 3BZ 0.8957
530 3FH 0.8956
531 PH2 0.8955
532 P3K 0.8955
533 HLR 0.8955
534 BRT 0.8954
535 GRE 0.8954
536 3C2 0.8953
537 8WT 0.8952
538 9FE 0.8952
539 173 0.8951
540 DRG 0.8951
541 SWD 0.8951
542 VXX 0.8950
543 4M4 0.8950
544 1WD 0.8949
545 H6B 0.8949
546 XQK 0.8947
547 EXO 0.8946
548 6M9 0.8946
549 DFB 0.8944
550 12M 0.8942
551 NDH 0.8940
552 F05 0.8939
553 ANF 0.8939
554 DHQ 0.8939
555 Q71 0.8938
556 9DA 0.8938
557 TIU 0.8938
558 EJZ 0.8937
559 YQA 0.8937
560 6M4 0.8937
561 GOX 0.8936
562 N2I 0.8935
563 XXR 0.8935
564 KKN 0.8934
565 AY4 0.8933
566 7FF 0.8932
567 3C1 0.8932
568 F9Y 0.8931
569 9EW 0.8930
570 ISE 0.8930
571 KJU 0.8928
572 0FN 0.8927
573 3R6 0.8927
574 EDM 0.8926
575 6MP 0.8926
576 EOL 0.8926
577 PM6 0.8925
578 BMA 0.8925
579 8MO 0.8924
580 6F0 0.8924
581 FA6 0.8922
582 TNF 0.8921
583 CH9 0.8921
584 6M1 0.8920
585 THA 0.8920
586 CTL 0.8918
587 TNL 0.8918
588 ADZ 0.8918
589 AMG 0.8914
590 SR4 0.8914
591 JXW 0.8914
592 7WA 0.8912
593 X6X 0.8912
594 F69 0.8910
595 ASO 0.8910
596 7W4 0.8908
597 7MU 0.8908
598 EYK 0.8907
599 FHN 0.8906
600 F5B 0.8906
601 HKD 0.8906
602 LKA 0.8905
603 IHB 0.8905
604 7MH 0.8905
605 ES7 0.8904
606 OVP 0.8904
607 11S 0.8903
608 N2Z 0.8903
609 YIO 0.8903
610 HHR 0.8902
611 TVP 0.8902
612 1P7 0.8901
613 7VJ 0.8900
614 W8G 0.8900
615 GCW 0.8899
616 DBX 0.8899
617 ES4 0.8897
618 HA7 0.8896
619 RD4 0.8895
620 32X 0.8894
621 3PF 0.8894
622 BP1 0.8893
623 X0V 0.8893
624 2F6 0.8893
625 6AI 0.8892
626 X05 0.8891
627 LT2 0.8891
628 PJW 0.8891
629 GCO 0.8891
630 GTZ 0.8890
631 PXM 0.8890
632 06B 0.8890
633 FDR 0.8890
634 BSP 0.8888
635 F60 0.8888
636 5VL 0.8887
637 V6F 0.8887
638 SWA 0.8886
639 39U 0.8885
640 LDP 0.8885
641 KDV 0.8885
642 6OT 0.8885
643 2HQ 0.8885
644 XQ0 0.8885
645 SLS 0.8884
646 CN0 0.8883
647 HXX 0.8882
648 9UL 0.8882
649 069 0.8882
650 4AN 0.8881
651 GJP 0.8878
652 ESI 0.8878
653 EQT 0.8877
654 3J8 0.8877
655 ET2 0.8876
656 5H1 0.8875
657 AHR 0.8874
658 14O 0.8874
659 2K4 0.8874
660 1HN 0.8873
661 5MB 0.8873
662 FBV 0.8873
663 JG8 0.8872
664 AEZ 0.8871
665 F81 0.8871
666 TT4 0.8870
667 B56 0.8870
668 5MI 0.8869
669 2ZV 0.8869
670 JAE 0.8869
671 KLK 0.8868
672 ISN 0.8867
673 GIM 0.8866
674 AX3 0.8866
675 MWP 0.8865
676 HMH 0.8864
677 JXN 0.8864
678 0GY 0.8863
679 QIC 0.8862
680 4RU 0.8862
681 A29 0.8861
682 2MN 0.8860
683 8W9 0.8860
684 2A9 0.8860
685 J01 0.8860
686 SOE 0.8859
687 VNJ 0.8858
688 ZME 0.8857
689 EGR 0.8855
690 G12 0.8854
691 K8X 0.8853
692 8NX 0.8853
693 3OC 0.8852
694 TRA 0.8851
695 SXS 0.8851
696 IPB 0.8850
697 4HM 0.8850
698 SYV 0.8849
699 0XT 0.8846
700 5B1 0.8845
701 9R5 0.8845
702 2LP 0.8844
703 ES9 0.8843
704 1XA 0.8843
705 RPQ 0.8840
706 FBB 0.8840
707 QM1 0.8839
708 9PY 0.8839
709 H4N 0.8839
710 VOH 0.8839
711 8OZ 0.8838
712 EUG 0.8835
713 36R 0.8835
714 MZB 0.8835
715 8VN 0.8833
716 4SX 0.8833
717 K6X 0.8831
718 2O6 0.8830
719 FUL 0.8830
720 KYD 0.8829
721 61O 0.8828
722 K2P 0.8827
723 L99 0.8827
724 NGO 0.8827
725 Q7A 0.8827
726 EMZ 0.8826
727 LNR 0.8823
728 3SK 0.8821
729 18N 0.8820
730 2DR 0.8819
731 TFU 0.8819
732 FK1 0.8819
733 XXP 0.8816
734 ICT 0.8815
735 ES2 0.8814
736 VGD 0.8814
737 ZZT 0.8814
738 82I 0.8814
739 ALL 0.8814
740 PA1 0.8813
741 5QY 0.8812
742 K2T 0.8810
743 HHT 0.8808
744 WOO 0.8807
745 G2F 0.8807
746 XIY 0.8806
747 8H8 0.8806
748 CLW 0.8806
749 ASC 0.8806
750 SE2 0.8805
751 3ID 0.8805
752 4VS 0.8805
753 293 0.8805
754 MAN 0.8804
755 HFB 0.8804
756 4ZC 0.8803
757 AJY 0.8803
758 M3Q 0.8802
759 6KT 0.8800
760 E35 0.8800
761 2JK 0.8800
762 4JT 0.8800
763 CWJ 0.8800
764 G3E 0.8800
765 BCF 0.8800
766 D48 0.8799
767 IFL 0.8799
768 DX3 0.8797
769 HTP 0.8797
770 FB1 0.8797
771 SJ5 0.8796
772 1P8 0.8796
773 ZWZ 0.8795
774 MB1 0.8795
775 ZON 0.8794
776 4JQ 0.8792
777 PZI 0.8792
778 B2J 0.8790
779 0W1 0.8788
780 49O 0.8787
781 3GQ 0.8786
782 ROI 0.8785
783 BZJ 0.8785
784 GLT 0.8784
785 B5D 0.8784
786 HQJ 0.8784
787 N3W 0.8783
788 INS 0.8783
789 GT0 0.8783
790 AX7 0.8782
791 BBF 0.8782
792 TBP 0.8781
793 EKZ 0.8781
794 5GU 0.8781
795 GXY 0.8780
796 DQA 0.8776
797 J5I 0.8776
798 5VM 0.8775
799 3XX 0.8775
800 MAJ 0.8773
801 3Z7 0.8772
802 JFD 0.8770
803 DMD 0.8769
804 KOJ 0.8768
805 G4D 0.8768
806 LT3 0.8768
807 20J 0.8766
808 XFE 0.8766
809 51R 0.8765
810 1DW 0.8765
811 ZZZ 0.8760
812 MT5 0.8760
813 GAF 0.8759
814 1A7 0.8759
815 NOY 0.8759
816 ENL 0.8758
817 4XR 0.8757
818 6RQ 0.8757
819 BCU 0.8757
820 4FH 0.8755
821 94W 0.8754
822 3TJ 0.8754
823 X0W 0.8753
824 DEE 0.8752
825 1U1 0.8751
826 GXL 0.8750
827 270 0.8750
828 DQN 0.8750
829 Q02 0.8749
830 3DO 0.8748
831 BPY 0.8748
832 1WC 0.8747
833 8VE 0.8746
834 GLY PRO 0.8746
835 JZ3 0.8746
836 DK1 0.8745
837 FDK 0.8745
838 1U6 0.8744
839 RM4 0.8743
840 IFM 0.8743
841 8NY 0.8742
842 DHS 0.8740
843 KDO 0.8740
844 IBF 0.8740
845 1KP 0.8739
846 ABV 0.8736
847 XCZ 0.8736
848 R8A 0.8736
849 2D3 0.8736
850 IFP 0.8735
851 MQN 0.8735
852 GCV 0.8734
853 F3B 0.8733
854 2MI 0.8731
855 QUZ 0.8729
856 FBT 0.8728
857 TXW 0.8726
858 MXX 0.8726
859 FRU 0.8724
860 4P5 0.8723
861 5PX 0.8723
862 OXZ 0.8721
863 SBK 0.8720
864 E3D 0.8718
865 P92 0.8718
866 LAO 0.8715
867 2J9 0.8715
868 5AN 0.8714
869 K97 0.8713
870 R9Y 0.8712
871 QWN 0.8712
872 4YO 0.8712
873 MFB 0.8710
874 NPY 0.8709
875 AX2 0.8709
876 2BG 0.8708
877 JU2 0.8707
878 2HC 0.8705
879 2K8 0.8704
880 5CL 0.8704
881 NIZ 0.8702
882 0TU 0.8701
883 27B 0.8701
884 PBA 0.8700
885 NK 0.8700
886 35C 0.8700
887 LYL 0.8697
888 1M2 0.8697
889 2CK 0.8696
890 KTW 0.8693
891 RNS 0.8693
892 9UG 0.8691
893 PEZ 0.8691
894 FUC 0.8690
895 TH7 0.8690
896 JA8 0.8689
897 PHB 0.8689
898 GNM 0.8688
899 4A5 0.8688
900 NPO 0.8685
901 463 0.8683
902 I59 0.8682
903 47J 0.8682
904 BZ2 0.8681
905 SF9 0.8680
906 P84 0.8679
907 N7P 0.8679
908 L5V 0.8678
909 ZB1 0.8678
910 TYL 0.8677
911 PCI 0.8677
912 QQQ 0.8675