Receptor
PDB id Resolution Class Description Source Keywords
5XWC 1.75 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF ASPERGILLUS NIGER GLUTAMATE DEHYDROGENA COMPLEXED WITH ALPHA-IMINOGLUTARATE, 2-AMINO-2-HYDROXYGLUTAN ADP ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE ASPERGILLUS NIGER ALPHA-IMINOGLUTAAMINO-2-HYDROXYGLUTARATE NADP COENZYME REACTION INTERMEDOXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR THE CATALYTIC MECHANISM AND ALPHA-KETOGLUTARATE COOPERATIVITY OF GLUTAMATE DEHYDROGENASE. J. BIOL. CHEM. V. 293 6241 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PEG A:553;
Invalid;
none;
submit data
106.12 C4 H10 O3 C(COC...
GOL A:549;
A:520;
A:525;
A:531;
A:537;
A:530;
A:513;
A:507;
A:504;
A:524;
A:551;
A:546;
A:518;
A:529;
A:543;
A:512;
A:544;
A:547;
A:509;
A:516;
A:519;
A:510;
A:540;
A:515;
A:535;
A:514;
A:505;
A:523;
A:528;
A:506;
A:532;
A:538;
A:552;
A:542;
A:517;
A:522;
A:527;
A:526;
A:548;
A:550;
A:534;
A:521;
A:541;
A:536;
A:533;
A:539;
A:545;
A:508;
A:511;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NAP A:501;
Valid;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
8GL A:502;
Valid;
none;
submit data
163.129 C5 H9 N O5 C(C[C...
2IT A:503;
Valid;
none;
submit data
145.113 C5 H7 N O4 [H]/N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5XWC 1.75 Å EC: 1.-.-.- CRYSTAL STRUCTURE OF ASPERGILLUS NIGER GLUTAMATE DEHYDROGENA COMPLEXED WITH ALPHA-IMINOGLUTARATE, 2-AMINO-2-HYDROXYGLUTAN ADP ASPERGILLUS NIGER GLUTAMATE DEHYDROGENASE ASPERGILLUS NIGER ALPHA-IMINOGLUTAAMINO-2-HYDROXYGLUTARATE NADP COENZYME REACTION INTERMEDOXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR THE CATALYTIC MECHANISM AND ALPHA-KETOGLUTARATE COOPERATIVITY OF GLUTAMATE DEHYDROGENASE. J. BIOL. CHEM. V. 293 6241 2018
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 383 families.
1 5XW0 - 8G0 C8 H6 O4 c1cc(cc(c1....
2 5XWC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 5XVX - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
4 5XVV - AKG C5 H6 O5 C(CC(=O)O)....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 337 families.
1 5XW0 - 8G0 C8 H6 O4 c1cc(cc(c1....
2 5XWC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 5XVX - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
4 5XVV - AKG C5 H6 O5 C(CC(=O)O)....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1BGV - GLU C5 H9 N O4 C(CC(=O)O)....
2 5XW0 - 8G0 C8 H6 O4 c1cc(cc(c1....
3 5XWC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 5XVX - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
5 5XVV - AKG C5 H6 O5 C(CC(=O)O)....
6 5IJZ - AKG C5 H6 O5 C(CC(=O)O)....
7 5GUD - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NAP; Similar ligands found: 140
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 NAD IBO 0.716667 0.972222
8 NAD TDB 0.716667 0.972222
9 A3D 0.712 0.972603
10 NBP 0.707692 0.935065
11 NHD 0.68254 0.958904
12 NJP 0.661417 0.972973
13 NFD 0.658915 0.934211
14 DND 0.619048 0.959459
15 AMP NAD 0.606061 0.958904
16 ZID 0.605839 0.972603
17 NAQ 0.59854 0.922078
18 ATR 0.59292 0.917808
19 NAE 0.591241 0.946667
20 NDE 0.58042 0.986301
21 A22 0.571429 0.958904
22 NAJ 0.567164 0.986111
23 A2R 0.563025 0.932432
24 NDC 0.561644 0.922078
25 NA7 0.552846 0.907895
26 ODP 0.551471 0.935065
27 A2P 0.539823 0.930556
28 8ID 0.537313 0.910256
29 NAD BBN 0.525974 0.865854
30 NPW 0.525547 0.8875
31 NZQ 0.521739 0.910256
32 CNA 0.521739 0.959459
33 NAD CJ3 0.519231 0.835294
34 NDP 0.514493 0.922078
35 PO4 PO4 A A A A PO4 0.503937 0.930556
36 1DG 0.503401 0.922078
37 DG1 0.503401 0.922078
38 TXP 0.5 0.922078
39 NMN AMP PO4 0.492958 0.921053
40 XNP 0.492958 0.875
41 25L 0.492308 0.958904
42 25A 0.492063 0.972222
43 NAD NDT 0.490909 0.747368
44 NMN 0.486726 0.888889
45 NGD 0.485714 0.935065
46 9JJ 0.481707 0.8875
47 2AM 0.477876 0.891892
48 NDP DTT 0.461538 0.843373
49 ADP 0.458333 0.945205
50 ADP MG 0.454545 0.944444
51 ADP BEF 0.454545 0.944444
52 A7R 0.452555 0.846154
53 PAP 0.451613 0.931507
54 A2D 0.445378 0.945205
55 AN2 0.442623 0.932432
56 7L1 0.441558 0.777778
57 ADP PO3 0.44 0.944444
58 AGS 0.44 0.896104
59 ATP MG 0.44 0.944444
60 M33 0.439024 0.906667
61 AR6 AR6 0.438849 0.945205
62 BA3 0.438017 0.945205
63 VO4 ADP 0.4375 0.945946
64 BEF ADP 0.436508 0.918919
65 OAD 0.43609 0.92
66 ADP BMA 0.43609 0.92
67 DQV 0.435714 0.958904
68 HEJ 0.435484 0.945205
69 ATP 0.435484 0.945205
70 OOB 0.435115 0.958904
71 AP5 0.434426 0.945205
72 B4P 0.434426 0.945205
73 GAP 0.433071 0.92
74 0WD 0.432432 0.922078
75 5FA 0.432 0.945205
76 2A5 0.432 0.87013
77 AQP 0.432 0.945205
78 AT4 0.430894 0.907895
79 HQG 0.430769 0.932432
80 00A 0.428571 0.909091
81 8LQ 0.427481 0.907895
82 DAL AMP 0.427481 0.932432
83 CA0 0.427419 0.92
84 ANP MG 0.426357 0.932432
85 ALF ADP 0.426357 0.871795
86 9X8 0.425373 0.871795
87 KG4 0.424 0.92
88 ACP 0.424 0.92
89 NAJ PZO 0.423841 0.897436
90 9SN 0.423358 0.897436
91 WAQ 0.422222 0.884615
92 ACQ 0.421875 0.92
93 V3L 0.421875 0.945205
94 ADQ 0.421053 0.92
95 AR6 0.420635 0.918919
96 APR 0.420635 0.918919
97 ATP A 0.42029 0.958333
98 ATP A A A 0.42029 0.958333
99 CO7 0.419753 0.786517
100 3OD 0.419118 0.92
101 1ZZ 0.419118 0.841463
102 DLL 0.41791 0.958904
103 AD9 0.417323 0.92
104 OVE 0.416667 0.857143
105 NAX 0.416667 0.875
106 QA7 0.416667 0.896104
107 MYR AMP 0.416058 0.841463
108 AV2 0.415385 0.868421
109 A3P 0.414634 0.944444
110 NNR 0.414414 0.72973
111 ALF ADP 3PG 0.413793 0.8625
112 OMR 0.413793 0.831325
113 6YZ 0.412214 0.92
114 ANP 0.410853 0.92
115 A1R 0.410448 0.860759
116 45A 0.409836 0.893333
117 ABM 0.409836 0.893333
118 AMP 0.408333 0.944444
119 A 0.408333 0.944444
120 SON 0.408 0.933333
121 PPS 0.407692 0.829268
122 8LE 0.407692 0.896104
123 5AL 0.407692 0.932432
124 NAI 0.406897 0.909091
125 7D3 0.406504 0.857143
126 AMP MG 0.404959 0.930556
127 ADX 0.404762 0.829268
128 ATF 0.40458 0.907895
129 3UK 0.404412 0.945946
130 AMP DBH 0.404255 0.894737
131 139 0.402685 0.875
132 50T 0.401575 0.906667
133 8LH 0.401515 0.907895
134 SRP 0.401515 0.907895
135 B5V 0.40146 0.933333
136 3AM 0.4 0.90411
137 B5M 0.4 0.921053
138 A3R 0.4 0.860759
139 KMQ 0.4 0.883117
140 FA5 0.4 0.933333
Ligand no: 2; Ligand: 8GL; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 8GL 1 1
Ligand no: 3; Ligand: 2IT; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 2IT 1 1
2 SIN 0.5 0.625
3 AKG 0.423077 0.615385
Similar Ligands (3D)
Ligand no: 1; Ligand: NAP; Similar ligands found: 4
No: Ligand Similarity coefficient
1 TXD 0.9146
2 6V0 0.9079
3 AP0 0.8967
4 TXE 0.8646
Ligand no: 2; Ligand: 8GL; Similar ligands found: 392
No: Ligand Similarity coefficient
1 AKG 0.9719
2 2HG 0.9716
3 2FT 0.9701
4 GLU 0.9630
5 OGA 0.9627
6 GLN 0.9593
7 S2G 0.9565
8 ZGL 0.9545
9 DGN 0.9471
10 DGL 0.9433
11 ONL 0.9418
12 2IT 0.9410
13 9ON 0.9398
14 URQ 0.9352
15 PEP 0.9331
16 9SE 0.9323
17 41K 0.9309
18 LYS 0.9300
19 5XB 0.9287
20 LY0 0.9283
21 HIS 0.9278
22 3PG 0.9259
23 HG3 0.9259
24 ORN 0.9253
25 APG 0.9253
26 GUA 0.9249
27 7OD 0.9247
28 DHI 0.9245
29 HHI 0.9218
30 GGL 0.9217
31 MET 0.9215
32 ASP 0.9210
33 2D8 0.9203
34 HPV 0.9190
35 TIH 0.9185
36 MLT 0.9185
37 SEP 0.9178
38 HF2 0.9177
39 HGA 0.9177
40 0L1 0.9170
41 SME 0.9169
42 KDG 0.9163
43 LYN 0.9151
44 C5A 0.9147
45 URO 0.9147
46 DYT 0.9146
47 QY9 0.9146
48 LUQ 0.9141
49 7N0 0.9121
50 DAL DAL 0.9117
51 LMR 0.9113
52 MHO 0.9109
53 PHE 0.9107
54 0OC 0.9106
55 PGA 0.9085
56 X1R 0.9073
57 3LR 0.9062
58 SHV 0.9062
59 PAC 0.9049
60 DLY 0.9044
61 SYM 0.9042
62 GLY GLY 0.9041
63 ALA ALA 0.9041
64 J0Z 0.9041
65 FK8 0.9041
66 AL0 0.9038
67 DIR 0.9037
68 ACH 0.9031
69 MED 0.9031
70 O45 0.9028
71 9RH 0.9022
72 NLE 0.9020
73 LEU 0.9019
74 DPN 0.9019
75 9YT 0.9018
76 SMN 0.9013
77 DLT 0.9012
78 NFA 0.9012
79 RUJ 0.9010
80 0VT 0.9010
81 FF3 0.9010
82 OSE 0.9009
83 OOG 0.9001
84 A3M 0.9001
85 PO6 0.9000
86 5HY 0.8998
87 9J3 0.8995
88 13P 0.8995
89 ONH 0.8993
90 B3U 0.8992
91 KMH 0.8991
92 MUC 0.8988
93 E4P 0.8988
94 3YP 0.8983
95 FUD 0.8983
96 MSE 0.8981
97 CAX 0.8981
98 BNF 0.8981
99 HIC 0.8981
100 HL5 0.8978
101 MAH 0.8975
102 HFA 0.8974
103 R2P 0.8973
104 RAT 0.8972
105 49F 0.8971
106 SR1 0.8969
107 S2P 0.8968
108 KTA 0.8968
109 1GP 0.8966
110 2CO 0.8964
111 PIY 0.8963
112 GJZ 0.8962
113 MEV 0.8961
114 FLC 0.8957
115 GRO 0.8956
116 2PG 0.8952
117 9RW 0.8952
118 AVI 0.8950
119 NF3 0.8947
120 UN1 0.8946
121 ISZ 0.8946
122 TEO 0.8945
123 98J 0.8945
124 SKM 0.8944
125 PPY 0.8943
126 G3P 0.8941
127 SC2 0.8941
128 NIZ 0.8937
129 6JN 0.8937
130 XIZ 0.8935
131 ACA 0.8932
132 LFC 0.8930
133 J9N 0.8930
134 CFI 0.8929
135 TRC 0.8927
136 HSO 0.8927
137 QMP 0.8926
138 0V5 0.8925
139 GZ3 0.8924
140 FA1 0.8924
141 G3H 0.8924
142 791 0.8924
143 PIM 0.8921
144 AOS 0.8919
145 4FA 0.8918
146 A09 0.8917
147 IVL 0.8916
148 PJL 0.8916
149 URP 0.8911
150 KMT 0.8908
151 GCO 0.8906
152 TPA 0.8904
153 DMO 0.8902
154 MD0 0.8901
155 6TZ 0.8900
156 PZI 0.8895
157 XYL 0.8895
158 7C3 0.8891
159 HCI 0.8891
160 DAS 0.8889
161 7BC 0.8888
162 NCT 0.8887
163 OKG 0.8886
164 2AL 0.8884
165 3AL 0.8884
166 MZT 0.8881
167 Q9Z 0.8879
168 SHI 0.8879
169 PGH 0.8875
170 LX1 0.8874
171 PSE 0.8872
172 I1E 0.8872
173 8OZ 0.8872
174 7WG 0.8872
175 F9P 0.8871
176 ZZU 0.8869
177 1BN 0.8869
178 173 0.8868
179 152 0.8866
180 FOC 0.8866
181 8EW 0.8865
182 XYH 0.8863
183 RSO 0.8863
184 3CR 0.8862
185 DHB 0.8859
186 AFS 0.8859
187 2HC 0.8857
188 SD4 0.8855
189 OEG 0.8852
190 CCE 0.8851
191 PC 0.8850
192 CIT 0.8847
193 AHN 0.8846
194 MLE 0.8843
195 DHS 0.8843
196 CCD 0.8842
197 069 0.8838
198 R20 0.8836
199 FBM 0.8835
200 SKJ 0.8834
201 BHO 0.8834
202 JF6 0.8833
203 PLU 0.8831
204 DAR 0.8830
205 ZXD 0.8828
206 7A8 0.8828
207 DXP 0.8827
208 N6C 0.8825
209 SIN 0.8825
210 HL4 0.8824
211 CYX 0.8823
212 268 0.8821
213 DEZ 0.8820
214 650 0.8818
215 1L5 0.8813
216 DPF 0.8813
217 K7M 0.8813
218 PSJ 0.8810
219 AG2 0.8810
220 2BX 0.8807
221 DHY 0.8805
222 LNO 0.8804
223 DI6 0.8803
224 NNH 0.8802
225 A29 0.8801
226 RMN 0.8800
227 R9S 0.8799
228 XXG 0.8797
229 KPC 0.8797
230 J9Q 0.8796
231 3S5 0.8795
232 4WK 0.8791
233 CXF 0.8789
234 3HG 0.8788
235 F98 0.8787
236 PRA 0.8786
237 TYR 0.8786
238 7Q1 0.8786
239 DER 0.8785
240 6FZ 0.8785
241 258 0.8784
242 RBL 0.8784
243 CUW 0.8783
244 4PN 0.8782
245 FAN 0.8781
246 PEA 0.8779
247 5NI 0.8777
248 ICT 0.8771
249 PCS 0.8769
250 L5V 0.8769
251 TPO 0.8766
252 S8V 0.8765
253 MPV 0.8764
254 NLP 0.8764
255 NYL 0.8764
256 1AL 0.8764
257 MEQ 0.8763
258 DAB 0.8762
259 B40 0.8761
260 GVG 0.8761
261 HY1 0.8761
262 K6H 0.8761
263 M74 0.8760
264 3HP 0.8760
265 AT3 0.8759
266 HQJ 0.8757
267 CS2 0.8756
268 RNS 0.8756
269 IXW 0.8755
270 2EH 0.8754
271 SOR 0.8753
272 BHU 0.8753
273 YRL 0.8752
274 129 0.8748
275 61M 0.8747
276 D5X 0.8746
277 HDH 0.8744
278 CXP 0.8744
279 LNR 0.8742
280 1X4 0.8741
281 TAG 0.8740
282 B09 0.8738
283 XUL 0.8736
284 8SZ 0.8735
285 N3W 0.8733
286 TZE 0.8733
287 B85 0.8732
288 KPA 0.8731
289 4LR 0.8730
290 LTL 0.8729
291 HHH 0.8729
292 2F6 0.8729
293 SOL 0.8727
294 SYC 0.8726
295 GP9 0.8725
296 GLR 0.8722
297 ILO 0.8722
298 XSP 0.8719
299 AX3 0.8717
300 RNT 0.8717
301 ARG 0.8716
302 ROR 0.8709
303 S24 0.8708
304 P22 0.8707
305 2RH 0.8705
306 AMQ 0.8702
307 JDN 0.8702
308 7MU 0.8701
309 GTK 0.8698
310 4SX 0.8698
311 HDL 0.8694
312 264 0.8692
313 BHH 0.8692
314 P7Y 0.8692
315 RB5 0.8691
316 TZL 0.8688
317 FOM 0.8688
318 M5E 0.8687
319 CH9 0.8685
320 GWM 0.8684
321 PEL 0.8684
322 3QM 0.8681
323 M6H 0.8676
324 92P 0.8676
325 3OC 0.8675
326 DXG 0.8675
327 GVM 0.8674
328 HPS 0.8674
329 AEF 0.8673
330 G4D 0.8669
331 OEM 0.8666
332 MXN 0.8665
333 JZ7 0.8664
334 I38 0.8662
335 REL 0.8661
336 DHK 0.8660
337 N9J 0.8656
338 IP8 0.8655
339 KVP 0.8654
340 BNS 0.8651
341 SLZ 0.8649
342 GLO 0.8647
343 4P0 0.8646
344 MPH 0.8640
345 FP1 0.8638
346 MQB 0.8638
347 Q06 0.8637
348 MES 0.8636
349 4XV 0.8635
350 SAF 0.8635
351 L99 0.8631
352 PH3 0.8627
353 LDP 0.8625
354 LLH 0.8625
355 DHM 0.8623
356 SHO 0.8618
357 NLQ 0.8618
358 6NA 0.8616
359 HJH 0.8616
360 QUS 0.8614
361 23J 0.8612
362 4XS 0.8612
363 3BU 0.8612
364 ENV 0.8608
365 G8M 0.8608
366 Q07 0.8603
367 5RN 0.8601
368 N4B 0.8601
369 DTY 0.8594
370 53C 0.8592
371 GLY PRO 0.8589
372 JFJ 0.8589
373 LPK 0.8589
374 5FX 0.8588
375 261 0.8586
376 5RP 0.8585
377 HSX 0.8583
378 3MV 0.8580
379 256 0.8571
380 2LP 0.8568
381 BPY 0.8566
382 ICO 0.8566
383 SPD 0.8563
384 EDR 0.8561
385 HNK 0.8549
386 YPN 0.8543
387 FEH 0.8541
388 TZM 0.8539
389 TSS 0.8536
390 FA3 0.8535
391 IAC 0.8529
392 DHR 0.8525
Ligand no: 3; Ligand: 2IT; Similar ligands found: 665
No: Ligand Similarity coefficient
1 FLC 1.0000
2 GLU 1.0000
3 S2G 0.9959
4 OGA 0.9938
5 GLN 0.9920
6 DGL 0.9886
7 GGL 0.9830
8 2HG 0.9827
9 ONL 0.9810
10 DGN 0.9760
11 URQ 0.9746
12 9ON 0.9743
13 ZGL 0.9729
14 DAS 0.9650
15 HGA 0.9646
16 ASP 0.9629
17 MLT 0.9588
18 URP 0.9583
19 DIR 0.9581
20 ORN 0.9578
21 PZI 0.9568
22 O45 0.9550
23 MET 0.9546
24 7C3 0.9541
25 ASN 0.9541
26 NLE 0.9530
27 GUA 0.9529
28 0L1 0.9528
29 OKG 0.9522
30 CRN 0.9521
31 2FT 0.9515
32 OEG 0.9515
33 0VT 0.9506
34 SYM 0.9505
35 2AS 0.9505
36 QY9 0.9499
37 HIS 0.9485
38 LMR 0.9479
39 URO 0.9478
40 DZA 0.9477
41 3PG 0.9474
42 HG3 0.9459
43 FK8 0.9455
44 K6H 0.9450
45 OAA 0.9449
46 SEP 0.9448
47 9J3 0.9448
48 TAR 0.9446
49 MHO 0.9441
50 KMT 0.9435
51 J0Z 0.9427
52 3HG 0.9416
53 SPA 0.9411
54 8GL 0.9410
55 TYL 0.9406
56 SME 0.9404
57 SRT 0.9392
58 LYS 0.9389
59 3YP 0.9381
60 HPV 0.9380
61 GZ3 0.9377
62 R2P 0.9371
63 PAC 0.9370
64 173 0.9368
65 TIH 0.9364
66 DAL DAL 0.9360
67 98J 0.9359
68 AL0 0.9356
69 VAH 0.9355
70 IZC 0.9355
71 TLA 0.9350
72 DLY 0.9349
73 PEP 0.9343
74 DYT 0.9341
75 7OD 0.9339
76 OSE 0.9334
77 TCA 0.9334
78 KDG 0.9325
79 3LR 0.9325
80 RUJ 0.9323
81 GRO 0.9319
82 HIO 0.9316
83 MSL 0.9313
84 COI 0.9312
85 LEU 0.9310
86 1SA 0.9309
87 LYN 0.9308
88 PO6 0.9308
89 7BC 0.9307
90 OHP 0.9306
91 4HP 0.9298
92 PIM 0.9297
93 PGA 0.9295
94 I4B 0.9291
95 GPJ 0.9291
96 R9S 0.9289
97 9X6 0.9286
98 MUC 0.9284
99 SPV 0.9282
100 BNF 0.9282
101 GLY GLY 0.9278
102 PHB 0.9278
103 HL5 0.9275
104 1BN 0.9270
105 SHI 0.9269
106 ITN 0.9267
107 2CO 0.9265
108 SHV 0.9262
109 9RW 0.9261
110 5HY 0.9260
111 TEO 0.9258
112 5XB 0.9256
113 3HP 0.9254
114 SMN 0.9253
115 OEM 0.9252
116 IOM 0.9249
117 NM3 0.9248
118 XIZ 0.9247
119 KTA 0.9242
120 3S5 0.9240
121 S2P 0.9234
122 ALA ALA 0.9233
123 NPO 0.9233
124 DAB 0.9232
125 OTR 0.9231
126 TZE 0.9227
127 7N0 0.9226
128 8OZ 0.9225
129 BNL 0.9223
130 PHU 0.9222
131 G3P 0.9218
132 49F 0.9214
133 3SL 0.9211
134 SAN 0.9211
135 MLE 0.9209
136 CUW 0.9206
137 TSU 0.9204
138 GPF 0.9202
139 7UC 0.9200
140 PBZ 0.9200
141 I38 0.9198
142 HSO 0.9196
143 HY1 0.9194
144 AHN 0.9192
145 HMS 0.9191
146 6JN 0.9191
147 92K 0.9190
148 PPR 0.9190
149 13P 0.9190
150 6NA 0.9188
151 AG2 0.9187
152 S8V 0.9187
153 RMN 0.9186
154 PG3 0.9185
155 DHB 0.9185
156 PMF 0.9185
157 UGC 0.9184
158 GP9 0.9184
159 MSR 0.9180
160 HCI 0.9179
161 DHI 0.9177
162 R9M 0.9177
163 BHU 0.9174
164 PHE 0.9170
165 ILE 0.9169
166 IXW 0.9167
167 OOG 0.9164
168 ONH 0.9164
169 MSE 0.9163
170 CCE 0.9163
171 KMH 0.9162
172 AC6 0.9161
173 AT3 0.9160
174 CPZ 0.9160
175 A3M 0.9159
176 APG 0.9157
177 MED 0.9156
178 PEL 0.9155
179 ISZ 0.9155
180 152 0.9154
181 CXP 0.9152
182 SD4 0.9152
183 DPN 0.9152
184 MZT 0.9151
185 HC4 0.9149
186 PRA 0.9149
187 8EW 0.9149
188 E4P 0.9149
189 IP8 0.9148
190 AAS 0.9148
191 P9P 0.9147
192 PGH 0.9147
193 K7M 0.9146
194 AOS 0.9146
195 449 0.9145
196 9YT 0.9144
197 MPJ 0.9144
198 A5E 0.9143
199 G3H 0.9141
200 FAN 0.9138
201 JYD 0.9138
202 UN1 0.9138
203 MEQ 0.9138
204 ACA 0.9138
205 Q9Z 0.9137
206 258 0.9137
207 SHO 0.9136
208 J9N 0.9136
209 268 0.9132
210 BEZ 0.9131
211 R20 0.9129
212 6TZ 0.9128
213 NLP 0.9127
214 NVA 0.9123
215 BHH 0.9121
216 4NC 0.9120
217 EHM 0.9120
218 PPY 0.9119
219 0V5 0.9119
220 GJZ 0.9117
221 3AL 0.9117
222 2AL 0.9117
223 DHY 0.9115
224 CCD 0.9114
225 CMS 0.9113
226 1Y6 0.9113
227 XRG 0.9113
228 6NT 0.9113
229 BHO 0.9110
230 PRO GLY 0.9107
231 HHH 0.9104
232 52C 0.9103
233 DHS 0.9101
234 PEQ 0.9101
235 HDA 0.9100
236 4LR 0.9099
237 717 0.9099
238 CFI 0.9099
239 FUM 0.9097
240 CHH 0.9097
241 NYL 0.9097
242 FCR 0.9095
243 MTL 0.9093
244 129 0.9092
245 HHI 0.9091
246 RAT 0.9091
247 RNS 0.9090
248 PH3 0.9090
249 PSE 0.9090
250 SYC 0.9089
251 271 0.9089
252 ACH 0.9088
253 HSE 0.9088
254 1F1 0.9087
255 XYL 0.9085
256 M4T 0.9085
257 SHF 0.9085
258 TYR 0.9084
259 X1S 0.9082
260 HX4 0.9081
261 HPN 0.9081
262 LTL 0.9080
263 URS 0.9080
264 NIZ 0.9079
265 97T 0.9078
266 SNU 0.9077
267 ICB 0.9077
268 HTX 0.9076
269 HBD 0.9075
270 1GP 0.9075
271 NM2 0.9075
272 650 0.9074
273 GLO 0.9074
274 PAH 0.9074
275 7A8 0.9073
276 B85 0.9073
277 DAV 0.9072
278 DS0 0.9068
279 SOR 0.9067
280 CXF 0.9066
281 HF2 0.9066
282 SLZ 0.9066
283 QMP 0.9065
284 HYA 0.9065
285 16D 0.9063
286 FBJ 0.9063
287 41K 0.9061
288 2PG 0.9060
289 AMS 0.9059
290 PSJ 0.9056
291 NF3 0.9055
292 3PP 0.9051
293 3OM 0.9050
294 HQJ 0.9046
295 N6C 0.9045
296 4PN 0.9044
297 LNO 0.9043
298 K34 0.9042
299 L5V 0.9040
300 N4B 0.9039
301 DE5 0.9039
302 FP1 0.9038
303 MD0 0.9036
304 TPA 0.9036
305 11C 0.9035
306 0OC 0.9034
307 9SE 0.9033
308 B40 0.9033
309 4J8 0.9032
310 8SZ 0.9031
311 I1E 0.9031
312 ROR 0.9030
313 4LW 0.9029
314 PBA 0.9029
315 NCT 0.9029
316 2RH 0.9027
317 DHM 0.9025
318 PLU 0.9024
319 RB5 0.9022
320 AEG 0.9022
321 PEA 0.9020
322 069 0.9020
323 JF6 0.9019
324 NXA 0.9017
325 LUQ 0.9017
326 TZL 0.9016
327 GVM 0.9015
328 CYX 0.9013
329 5XA 0.9013
330 FBM 0.9013
331 GAB 0.9013
332 HPS 0.9012
333 HSM 0.9010
334 51F 0.9010
335 LFC 0.9010
336 3OL 0.9009
337 GVG 0.9006
338 F9P 0.9005
339 PC 0.9004
340 SKJ 0.9003
341 6FZ 0.9002
342 HFA 0.9001
343 9X7 0.8999
344 2EH 0.8999
345 2BX 0.8997
346 RTK 0.8997
347 B3U 0.8997
348 MHN 0.8997
349 36Y 0.8996
350 MPH 0.8995
351 5NI 0.8995
352 ENV 0.8994
353 4MV 0.8993
354 P80 0.8990
355 VKC 0.8988
356 RBJ 0.8986
357 4SX 0.8986
358 NFA 0.8984
359 RSO 0.8984
360 JZ4 0.8984
361 P7Y 0.8983
362 FOC 0.8982
363 XUL 0.8981
364 TZF 0.8981
365 2LP 0.8980
366 J9Q 0.8980
367 SAF 0.8980
368 264 0.8980
369 2HC 0.8980
370 XBT 0.8979
371 RNT 0.8977
372 1DJ 0.8976
373 DAR 0.8976
374 LNR 0.8975
375 FQI 0.8974
376 BHL 0.8974
377 M3P 0.8974
378 AFS 0.8973
379 X0V 0.8972
380 FBS 0.8972
381 YRL 0.8971
382 A29 0.8969
383 HJH 0.8967
384 PIY 0.8967
385 MAH 0.8966
386 HCS 0.8965
387 2FM 0.8965
388 PBC 0.8963
389 N9J 0.8962
390 FEH 0.8962
391 JDN 0.8960
392 AMQ 0.8959
393 PD2 0.8958
394 RBL 0.8957
395 ICF 0.8954
396 M44 0.8950
397 FBW 0.8949
398 XDK 0.8947
399 69O 0.8945
400 2F6 0.8945
401 CEE 0.8944
402 M5E 0.8943
403 40E 0.8943
404 4LV 0.8942
405 FOM 0.8941
406 MXN 0.8941
407 MNN 0.8940
408 K6V 0.8939
409 1L5 0.8937
410 FUD 0.8937
411 4FH 0.8937
412 BAM 0.8935
413 AOT 0.8934
414 SC2 0.8934
415 HBU 0.8933
416 LDP 0.8933
417 TYE 0.8931
418 X1R 0.8929
419 4FA 0.8929
420 23J 0.8929
421 53C 0.8929
422 7WG 0.8924
423 XLS 0.8923
424 3BU 0.8923
425 GOJ 0.8923
426 LY0 0.8922
427 LPK 0.8917
428 DXG 0.8915
429 UYA 0.8914
430 BNS 0.8913
431 1LN 0.8912
432 THE 0.8911
433 5FX 0.8909
434 M6H 0.8909
435 F06 0.8908
436 GLY ALA 0.8908
437 3CR 0.8906
438 L99 0.8904
439 DII 0.8904
440 GLR 0.8898
441 MEV 0.8898
442 MPV 0.8898
443 ZBT 0.8898
444 P58 0.8897
445 OK7 0.8895
446 3MV 0.8894
447 7VP 0.8890
448 KPA 0.8890
449 MLZ 0.8889
450 2D8 0.8888
451 A09 0.8888
452 P81 0.8887
453 AEF 0.8885
454 NMG 0.8881
455 LT1 0.8879
456 DHR 0.8878
457 MES 0.8877
458 C5A 0.8877
459 HL4 0.8877
460 3C4 0.8876
461 EKZ 0.8876
462 PDC 0.8874
463 54D 0.8874
464 NSB 0.8874
465 Q02 0.8870
466 CCU 0.8869
467 261 0.8869
468 C1M 0.8868
469 3QM 0.8867
470 SSB 0.8867
471 LVD 0.8866
472 4VP 0.8863
473 3OC 0.8861
474 CH9 0.8860
475 HX2 0.8860
476 BRH 0.8858
477 Q03 0.8853
478 SKM 0.8851
479 ALE 0.8850
480 NWH 0.8847
481 CS2 0.8846
482 SDD 0.8846
483 CFA 0.8845
484 1X4 0.8845
485 HIC 0.8844
486 GWM 0.8842
487 P22 0.8841
488 NFM 0.8840
489 HDH 0.8839
490 QUS 0.8837
491 1Z6 0.8836
492 505 0.8835
493 BZ3 0.8835
494 HA5 0.8834
495 M3H 0.8831
496 RUY 0.8831
497 5WZ 0.8831
498 BSX 0.8830
499 263 0.8830
500 9GB 0.8827
501 1XA 0.8825
502 IFP 0.8825
503 IVL 0.8824
504 TIU 0.8824
505 PBN 0.8822
506 4TB 0.8820
507 61M 0.8819
508 PG0 0.8819
509 LSQ 0.8819
510 F4E 0.8818
511 1A7 0.8818
512 7QS 0.8818
513 SOL 0.8817
514 4CS 0.8817
515 KOJ 0.8816
516 5XC 0.8815
517 XSP 0.8815
518 PRY 0.8813
519 JRB 0.8813
520 7Q1 0.8812
521 GZ2 0.8811
522 HNK 0.8811
523 QFJ 0.8805
524 1DU 0.8805
525 8U3 0.8805
526 ORO 0.8804
527 4XS 0.8803
528 HPP 0.8803
529 TZM 0.8803
530 JZ7 0.8801
531 51R 0.8801
532 42J 0.8800
533 40F 0.8799
534 MAJ 0.8799
535 JFJ 0.8798
536 HDL 0.8796
537 R67 0.8794
538 KVP 0.8793
539 VXX 0.8792
540 FF3 0.8792
541 TPO 0.8791
542 PRZ 0.8789
543 TAG 0.8789
544 ARG 0.8789
545 HNL 0.8789
546 RP3 0.8781
547 9RH 0.8780
548 GCO 0.8776
549 MR1 0.8775
550 EN1 0.8774
551 S7A 0.8772
552 KTJ 0.8772
553 H95 0.8771
554 DER 0.8771
555 4XV 0.8770
556 R2B 0.8769
557 ASC 0.8767
558 DI6 0.8767
559 DXP 0.8765
560 3QO 0.8764
561 NIG 0.8764
562 PKU 0.8763
563 0F9 0.8760
564 0A9 0.8760
565 RLG 0.8759
566 DPF 0.8755
567 JB8 0.8755
568 5DL 0.8754
569 F98 0.8754
570 DYA 0.8753
571 A9P 0.8752
572 BPW 0.8752
573 QDK 0.8751
574 YCP 0.8748
575 AMH 0.8748
576 TT4 0.8747
577 XIY 0.8747
578 92P 0.8745
579 OCT 0.8744
580 SHA 0.8744
581 Q06 0.8741
582 7MU 0.8739
583 D1X 0.8739
584 DEZ 0.8739
585 1SH 0.8739
586 KPC 0.8739
587 XYH 0.8737
588 FHC 0.8736
589 1WC 0.8736
590 2BG 0.8734
591 GLY CYS 0.8731
592 C82 0.8731
593 YPN 0.8728
594 PPT 0.8727
595 B3M 0.8727
596 S24 0.8725
597 KP6 0.8725
598 DCL 0.8724
599 AX3 0.8724
600 OCA 0.8724
601 SSC 0.8720
602 ISD 0.8718
603 CSS 0.8716
604 LLQ 0.8709
605 IAC 0.8706
606 CAX 0.8704
607 8G0 0.8697
608 ENO 0.8691
609 ZXD 0.8689
610 NMH 0.8687
611 ONR 0.8687
612 CLU 0.8684
613 HSX 0.8681
614 PJW 0.8676
615 9YL 0.8676
616 NNH 0.8676
617 DLT 0.8675
618 HE2 0.8675
619 TRC 0.8673
620 O8Y 0.8664
621 ICO 0.8661
622 M58 0.8658
623 LLH 0.8654
624 AHC 0.8654
625 56D 0.8653
626 HXY 0.8649
627 S0W 0.8646
628 269 0.8642
629 AVI 0.8642
630 N2Z 0.8641
631 0JD 0.8641
632 EDR 0.8639
633 NSD 0.8638
634 M74 0.8636
635 1KA 0.8632
636 DQA 0.8625
637 XDE 0.8621
638 4XR 0.8618
639 M1Z 0.8617
640 IHG 0.8615
641 4WK 0.8612
642 PJL 0.8611
643 MMS 0.8606
644 RB0 0.8599
645 YIE 0.8597
646 G2H 0.8595
647 LYL 0.8594
648 ODO 0.8591
649 C2Y 0.8586
650 QBS 0.8585
651 PFF 0.8585
652 MZW 0.8578
653 DTY 0.8578
654 5RP 0.8576
655 XRS 0.8574
656 2UB 0.8564
657 M6W 0.8557
658 ABF 0.8556
659 TB8 0.8555
660 DEE 0.8553
661 4VY 0.8540
662 C2B 0.8536
663 F69 0.8532
664 CTV 0.8530
665 791 0.8524
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: 16
This union binding pocket(no: 2) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
1 1BXG HCI 28.6957
2 3ETG NDP 36.087
3 3ETG GLU 36.087
4 3ETG NDP 36.087
5 3ETG GLU 36.087
6 3ETG NDP 36.087
7 3ETG NDP 36.087
8 3ETG GLU 36.087
9 3ETG GLU 36.087
10 6YEI AKG 48.3092
11 6YEI NAD 48.3092
12 6YEI NAD 48.3092
13 6YEI NAD 48.3092
14 6YEI NAD 48.3092
15 6YEI NAD 48.3092
16 6YEI NAD 48.3092
Pocket No.: 3; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 5XWC; Ligand: 8GL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: 16
This union binding pocket(no: 8) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
1 1BXG HCI 28.6957
2 3ETG NDP 36.087
3 3ETG GLU 36.087
4 3ETG NDP 36.087
5 3ETG GLU 36.087
6 3ETG NDP 36.087
7 3ETG NDP 36.087
8 3ETG GLU 36.087
9 3ETG GLU 36.087
10 6YEI AKG 48.3092
11 6YEI NAD 48.3092
12 6YEI NAD 48.3092
13 6YEI NAD 48.3092
14 6YEI NAD 48.3092
15 6YEI NAD 48.3092
16 6YEI NAD 48.3092
Pocket No.: 9; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 5XWC; Ligand: NAP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 13) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 14; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: 16
This union binding pocket(no: 14) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
1 1BXG HCI 28.6957
2 3ETG NDP 36.087
3 3ETG GLU 36.087
4 3ETG NDP 36.087
5 3ETG GLU 36.087
6 3ETG NDP 36.087
7 3ETG NDP 36.087
8 3ETG GLU 36.087
9 3ETG GLU 36.087
10 6YEI AKG 48.3092
11 6YEI NAD 48.3092
12 6YEI NAD 48.3092
13 6YEI NAD 48.3092
14 6YEI NAD 48.3092
15 6YEI NAD 48.3092
16 6YEI NAD 48.3092
Pocket No.: 15; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 15) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 16; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 16) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 17; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 17) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 18; Query (leader) PDB : 5XWC; Ligand: 2IT; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 18) in the query (biounit: 5xwc.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
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