Receptor
PDB id Resolution Class Description Source Keywords
5Z9Q 1.8 Å EC: 5.6.2.2 BACTERIAL GYRB ATPASE DOMAIN IN COMPLEX WITH A CHEMICAL FRAG ESCHERICHIA COLI (STRAIN K12) DNA TOPOISOMERASE ANTIBACTERIAL DRUG TARGET FRAGMENT-BASEDISCOVERY ISOMERASE
Ref.: IDENTIFICATION OF AN AUXILIARY DRUGGABLE POCKET IN GYRASE ATPASE DOMAIN USING FRAGMENT PROBES MEDCHEMCOMM V. 9 1619 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:303;
A:301;
B:301;
A:302;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
HX4 A:304;
B:302;
Valid;
Valid;
none;
none;
submit data
159.188 C9 H9 N3 c1ccc...
AX7 A:305;
Valid;
none;
submit data
133.151 C7 H7 N3 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
7C7N 2.3 Å EC: 5.6.2.2 CRYSTAL STRUCTURE OF E.COLI DNA GYRASE B IN COMPLEX WITH 6-F (METHYLAMINO)-2-OXO-1,2-DIHYDROQUINOLINE DERIVATIVE ESCHERICHIA COLI INHIBITOR COMPLEX TOPOISOMERASE ESCHERICHIA COLI ISOMERA
Ref.: LEAD OPTIMIZATION OF 8-(METHYLAMINO)-2-OXO-1,2-DIHYDROQUINOLINES AS BACT TYPE II TOPOISOMERASE INHIBITORS. BIOORG.MED.CHEM. V. 28 15776 2020
Members (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 6KZV ic50 = 5.4 uM E0F C24 H27 N3 O2 CN(Cc1cccc....
2 6YD9 ic50 = 110 nM ON2 C16 H15 Cl2 N5 O2 S Cc1c(c(c([....
3 6F94 ic50 = 0.099 uM D0H C23 H25 N5 O2 CCNC(=O)Nc....
4 5Z9Q - HX4 C9 H9 N3 c1ccc(cc1)....
5 6KZX ic50 = 0.2 uM E0L C18 H15 N3 O4 CNc1cccc2c....
6 5Z4H - AX7 C7 H7 N3 c1ccc2c(c1....
7 5Z9L - 8H8 C7 H4 F N O c1cc(c(cc1....
8 5Z9E - AX7 C7 H7 N3 c1ccc2c(c1....
9 1KZN Kd = 1.2 nM CBN C35 H37 Cl N2 O11 Cc1ccc([nH....
10 1AJ6 Kd = 1.2 uM NOV C31 H36 N2 O11 Cc1c(ccc2c....
11 5Z9B - AX7 C7 H7 N3 c1ccc2c(c1....
12 6KZZ ic50 = 0.0017 uM E0R C18 H15 N3 O4 CNc1cccc2c....
13 5MMO - 9JG C22 H21 N5 O3 CCNC(=O)Nc....
14 6F86 ic50 = 0.037 uM CWW C17 H16 Br N7 O2 CCNC(=O)Nc....
15 5Z4O - HX8 C12 H10 O2 c1ccc(cc1)....
16 6F8J ic50 = 0.086 uM CZ5 C17 H17 N7 O2 CCNC(=O)Nc....
17 5MMP ic50 = 0.03 uM G3Z C22 H20 N6 O CCNC(=O)Nc....
18 4DUH Kd = 6.6 uM RLI C17 H16 N4 O3 S2 CCC(=O)Nc1....
19 7C7O ic50 = 0.52 nM FKU C21 H22 F N5 O4 CNc1cc(cc2....
20 7C7N ic50 = 0.36 nM FKR C18 H14 F N3 O4 CNc1cc(cc2....
21 5MMN ic50 = 0.125 uM O54 C19 H20 N4 O CCNC(=O)Nc....
22 6F96 ic50 = 0.019 uM D0K C21 H22 N6 O3 CCNC(=O)Nc....
23 5Z9F - AX7 C7 H7 N3 c1ccc2c(c1....
70% Homology Family (25)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6KZV ic50 = 5.4 uM E0F C24 H27 N3 O2 CN(Cc1cccc....
2 6YD9 ic50 = 110 nM ON2 C16 H15 Cl2 N5 O2 S Cc1c(c(c([....
3 6F94 ic50 = 0.099 uM D0H C23 H25 N5 O2 CCNC(=O)Nc....
4 5Z9Q - HX4 C9 H9 N3 c1ccc(cc1)....
5 6KZX ic50 = 0.2 uM E0L C18 H15 N3 O4 CNc1cccc2c....
6 5Z4H - AX7 C7 H7 N3 c1ccc2c(c1....
7 5Z9L - 8H8 C7 H4 F N O c1cc(c(cc1....
8 5Z9E - AX7 C7 H7 N3 c1ccc2c(c1....
9 1KZN Kd = 1.2 nM CBN C35 H37 Cl N2 O11 Cc1ccc([nH....
10 1AJ6 Kd = 1.2 uM NOV C31 H36 N2 O11 Cc1c(ccc2c....
11 5Z9B - AX7 C7 H7 N3 c1ccc2c(c1....
12 6KZZ ic50 = 0.0017 uM E0R C18 H15 N3 O4 CNc1cccc2c....
13 5MMO - 9JG C22 H21 N5 O3 CCNC(=O)Nc....
14 6F86 ic50 = 0.037 uM CWW C17 H16 Br N7 O2 CCNC(=O)Nc....
15 5Z4O - HX8 C12 H10 O2 c1ccc(cc1)....
16 6F8J ic50 = 0.086 uM CZ5 C17 H17 N7 O2 CCNC(=O)Nc....
17 5MMP ic50 = 0.03 uM G3Z C22 H20 N6 O CCNC(=O)Nc....
18 4DUH Kd = 6.6 uM RLI C17 H16 N4 O3 S2 CCC(=O)Nc1....
19 7C7O ic50 = 0.52 nM FKU C21 H22 F N5 O4 CNc1cc(cc2....
20 7C7N ic50 = 0.36 nM FKR C18 H14 F N3 O4 CNc1cc(cc2....
21 5MMN ic50 = 0.125 uM O54 C19 H20 N4 O CCNC(=O)Nc....
22 6F96 ic50 = 0.019 uM D0K C21 H22 N6 O3 CCNC(=O)Nc....
23 5Z9F - AX7 C7 H7 N3 c1ccc2c(c1....
24 6M1S Ki < 1 nM EZ9 C26 H23 F4 N7 O3 CCNc1cc(cc....
25 6M1J Ki = 2 nM EZ6 C24 H17 F4 N7 O2 CNc1cc(cc2....
50% Homology Family (67)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4URL ic50 = 500 nM XAM C44 H60 Cl2 N4 O14 Cc1c(c(c([....
2 5CTW - 55D C9 H12 N2 O2 S CCCC(=O)Nc....
3 5CTU - 54X C10 H6 N2 O S2 c1cc(sc1)c....
4 3U2D - 08B C16 H18 Br N5 O3 Cc1c(cc([n....
5 5CTX ic50 = 1.32 uM 55G C20 H13 N5 O S c1ccc(cc1)....
6 3TTZ ic50 = 0.004 uM 07N C15 H15 Cl2 F N4 O3 S Cc1c(c(c([....
7 5D6Q ic50 = 5.8 uM 57V C17 H17 N5 O S CCNC(=O)Nc....
8 3U2K - 087 C17 H18 Cl3 N5 O2 Cc1c(c(c([....
9 5D6P ic50 = 2.5 uM 57U C11 H14 N4 O2 S CCNC(=O)Nc....
10 5Z9P - AX7 C7 H7 N3 c1ccc2c(c1....
11 5D7C ic50 = 0.14 uM 57W C20 H18 N6 O CCNC(=O)Nc....
12 6TCK - N1N C21 H15 Cl2 N3 O4 S Cc1c(c(c([....
13 5CPH - EVO C14 H10 N2 O c1ccc2c(c1....
14 6YD9 ic50 = 110 nM ON2 C16 H15 Cl2 N5 O2 S Cc1c(c(c([....
15 6F94 ic50 = 0.099 uM D0H C23 H25 N5 O2 CCNC(=O)Nc....
16 5Z9Q - HX4 C9 H9 N3 c1ccc(cc1)....
17 6KZX ic50 = 0.2 uM E0L C18 H15 N3 O4 CNc1cccc2c....
18 5Z4H - AX7 C7 H7 N3 c1ccc2c(c1....
19 5Z9L - 8H8 C7 H4 F N O c1cc(c(cc1....
20 5Z9E - AX7 C7 H7 N3 c1ccc2c(c1....
21 1KZN Kd = 1.2 nM CBN C35 H37 Cl N2 O11 Cc1ccc([nH....
22 1AJ6 Kd = 1.2 uM NOV C31 H36 N2 O11 Cc1c(ccc2c....
23 5Z9B - AX7 C7 H7 N3 c1ccc2c(c1....
24 6KZZ ic50 = 0.0017 uM E0R C18 H15 N3 O4 CNc1cccc2c....
25 5MMO - 9JG C22 H21 N5 O3 CCNC(=O)Nc....
26 6F86 ic50 = 0.037 uM CWW C17 H16 Br N7 O2 CCNC(=O)Nc....
27 5Z4O - HX8 C12 H10 O2 c1ccc(cc1)....
28 6F8J ic50 = 0.086 uM CZ5 C17 H17 N7 O2 CCNC(=O)Nc....
29 5MMP ic50 = 0.03 uM G3Z C22 H20 N6 O CCNC(=O)Nc....
30 4DUH Kd = 6.6 uM RLI C17 H16 N4 O3 S2 CCC(=O)Nc1....
31 7C7O ic50 = 0.52 nM FKU C21 H22 F N5 O4 CNc1cc(cc2....
32 7C7N ic50 = 0.36 nM FKR C18 H14 F N3 O4 CNc1cc(cc2....
33 5MMN ic50 = 0.125 uM O54 C19 H20 N4 O CCNC(=O)Nc....
34 6F96 ic50 = 0.019 uM D0K C21 H22 N6 O3 CCNC(=O)Nc....
35 5Z9F - AX7 C7 H7 N3 c1ccc2c(c1....
36 6ENH - BHW C55 H59 N5 O20 Cc1ccc([nH....
37 1KIJ - NOV C31 H36 N2 O11 Cc1c(ccc2c....
38 4WUB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
39 4PRX - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
40 6ENG - BHW C55 H59 N5 O20 Cc1ccc([nH....
41 4XTJ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
42 1EI1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
43 4PU9 - ADP BEF n/a n/a
44 4WUC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
45 4PRV - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
46 4WUD - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
47 4ZVI Kd = 0.47 uM 4S4 C14 H11 Br2 N3 O4 c1cc(ccc1C....
48 1S16 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
49 4URN - NOV C31 H36 N2 O11 Cc1c(ccc2c....
50 4HY1 Ki = 2 nM 19X C20 H19 Cl N6 O S CCc1c(c2c(....
51 4HYM Ki = 6 nM CJC C19 H19 Cl N8 O S CCc1c(c2c(....
52 4HXW Ki = 2 nM 1A0 C19 H19 Cl N8 S CCc1c(c2c(....
53 4GFN Ki = 5 nM SUY C17 H18 Cl N7 S CCc1c(c2c(....
54 4P8O - 883 C19 H16 F N7 O CCNC(=O)Nc....
55 6Y8N ic50 = 9 nM OGH C21 H21 F N8 O Cc1ncc(cn1....
56 6Y8L - NOV C31 H36 N2 O11 Cc1c(ccc2c....
57 4B6C ic50 = 0.69 uM B5U C27 H34 N6 O2 Cc1ccc(cc1....
58 4LP0 ic50 < 10 nM 1YM C18 H14 F3 N5 O3 S CCNC(=O)Nc....
59 4EMV ic50 = 0.005 uM 0R9 C20 H15 F3 N6 O3 CCNC(=O)c1....
60 4MB9 - 28F C18 H20 N6 O3 S CCNC(=O)Nc....
61 4MBC - 28G C21 H24 N6 O3 S C=CCNC(=O)....
62 4LPB ic50 < 10 nM 1YP C19 H14 F3 N7 O3 S CCNC(=O)Nc....
63 4MOT - 2B7 C20 H23 N5 O2 S CC(C)CCN1c....
64 4EM7 ic50 = 7.7 uM 0RA C16 H14 N2 O2 c1cc(cc(c1....
65 6M1S Ki < 1 nM EZ9 C26 H23 F4 N7 O3 CCNc1cc(cc....
66 6M1J Ki = 2 nM EZ6 C24 H17 F4 N7 O2 CNc1cc(cc2....
67 4BAE ic50 = 3 nM RWX C19 H21 Br Cl N7 O4 S Cc1c(c(c([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: HX4; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 HX4 1 1
Ligand no: 2; Ligand: AX7; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 AX7 1 1
2 VGD 0.465116 0.875
3 36E 0.452381 0.606061
4 1M2 0.452381 0.9
5 ET2 0.431818 0.875
Similar Ligands (3D)
Ligand no: 1; Ligand: HX4; Similar ligands found: 938
No: Ligand Similarity coefficient
1 IWT 1.0000
2 7VP 0.9986
3 J9N 0.9942
4 BNL 0.9807
5 4V2 0.9788
6 0BP 0.9772
7 PIM 0.9761
8 795 0.9727
9 92G 0.9720
10 PPY 0.9713
11 M3H 0.9697
12 0NX 0.9688
13 RA7 0.9681
14 PIY 0.9679
15 HCI 0.9667
16 L22 0.9641
17 AOT 0.9629
18 MSR 0.9627
19 TT4 0.9624
20 GVY 0.9622
21 PO6 0.9601
22 4LW 0.9601
23 MPV 0.9594
24 XDK 0.9585
25 GVG 0.9585
26 N9J 0.9582
27 CPZ 0.9577
28 6TZ 0.9576
29 BZ2 0.9573
30 SNU 0.9573
31 F4E 0.9566
32 TCA 0.9563
33 HNH 0.9560
34 TZF 0.9557
35 XIZ 0.9555
36 M45 0.9553
37 ESP 0.9552
38 R20 0.9549
39 36Y 0.9547
40 CK2 0.9543
41 JF6 0.9541
42 D3G 0.9536
43 ESX 0.9534
44 1A7 0.9530
45 HIC 0.9526
46 L5V 0.9519
47 HQJ 0.9518
48 A5E 0.9512
49 1Z6 0.9511
50 CH9 0.9511
51 KTJ 0.9510
52 B1J 0.9502
53 K34 0.9489
54 NCT 0.9487
55 FZM 0.9481
56 N2Z 0.9478
57 DHI 0.9477
58 52C 0.9476
59 97T 0.9470
60 HIS 0.9465
61 1L5 0.9449
62 EN1 0.9443
63 C1M 0.9441
64 50C 0.9436
65 ICB 0.9431
66 X48 0.9431
67 HNL 0.9430
68 TIH 0.9427
69 2HC 0.9426
70 PJW 0.9426
71 2F6 0.9423
72 J9Q 0.9423
73 4XF 0.9419
74 TYL 0.9415
75 CFI 0.9413
76 46P 0.9409
77 4LV 0.9408
78 6FZ 0.9407
79 X0U 0.9406
80 PHE 0.9406
81 G14 0.9405
82 AN3 0.9403
83 EYV 0.9402
84 FK8 0.9402
85 ENO 0.9396
86 PH3 0.9392
87 JRB 0.9392
88 K7M 0.9387
89 4WL 0.9384
90 DE5 0.9383
91 NFA 0.9383
92 S8V 0.9379
93 L03 0.9374
94 E3X 0.9374
95 492 0.9371
96 ISZ 0.9371
97 4ZA 0.9368
98 R2P 0.9368
99 HFA 0.9364
100 BP7 0.9363
101 1IT 0.9360
102 GO2 0.9359
103 URO 0.9359
104 ZZA 0.9357
105 9FL 0.9356
106 6FB 0.9356
107 9CA 0.9354
108 ODK 0.9353
109 56D 0.9351
110 HHI 0.9351
111 4P5 0.9347
112 BPY 0.9347
113 HNK 0.9336
114 GZ2 0.9334
115 BHO 0.9332
116 RUY 0.9331
117 AKG 0.9330
118 F4K 0.9329
119 P80 0.9325
120 PHU 0.9325
121 XCG 0.9321
122 J6W 0.9320
123 HL4 0.9319
124 4JQ 0.9316
125 C82 0.9314
126 7OD 0.9311
127 HDH 0.9310
128 FHC 0.9303
129 2BG 0.9297
130 XIY 0.9297
131 15E 0.9295
132 PAC 0.9291
133 4HB 0.9290
134 7O4 0.9290
135 ESI 0.9285
136 L13 0.9283
137 NIZ 0.9281
138 4BY 0.9281
139 P81 0.9279
140 3YP 0.9279
141 BCU 0.9278
142 4Z3 0.9276
143 3A9 0.9276
144 BZE 0.9275
145 0HN 0.9275
146 A29 0.9272
147 363 0.9270
148 TYR 0.9269
149 ALE 0.9269
150 XDE 0.9269
151 M4T 0.9268
152 OTR 0.9268
153 OGA 0.9268
154 HC4 0.9267
155 SQ4 0.9266
156 FBM 0.9264
157 36E 0.9263
158 2ZM 0.9262
159 4BL 0.9260
160 TMG 0.9260
161 JAW 0.9260
162 N3W 0.9258
163 3ZB 0.9256
164 61M 0.9254
165 8ZE 0.9254
166 0HO 0.9253
167 N2I 0.9252
168 YZM 0.9251
169 6SD 0.9251
170 C53 0.9245
171 DPN 0.9244
172 1F1 0.9244
173 6NI 0.9242
174 CK1 0.9239
175 JAH 0.9238
176 1WC 0.9234
177 5LA 0.9232
178 E5X 0.9232
179 QUS 0.9231
180 4YO 0.9231
181 LQ2 0.9231
182 MQN 0.9230
183 268 0.9229
184 3VQ 0.9227
185 HXY 0.9222
186 1M2 0.9221
187 L14 0.9220
188 B40 0.9220
189 TYE 0.9218
190 PNZ 0.9218
191 S2G 0.9216
192 BVA 0.9214
193 2QC 0.9214
194 LNR 0.9212
195 HSO 0.9211
196 AMH 0.9209
197 PUE 0.9208
198 KTW 0.9208
199 0TU 0.9208
200 6NT 0.9205
201 BNF 0.9204
202 BZJ 0.9203
203 EOU 0.9201
204 I1E 0.9201
205 5QY 0.9201
206 9ZE 0.9200
207 E1T 0.9200
208 TGX 0.9199
209 0JD 0.9197
210 BQ2 0.9197
211 6KT 0.9197
212 5VL 0.9196
213 GT4 0.9195
214 HPP 0.9195
215 HJH 0.9191
216 KDV 0.9190
217 UNJ 0.9190
218 T2D 0.9188
219 173 0.9186
220 SWX 0.9183
221 4BZ 0.9183
222 428 0.9180
223 15N 0.9176
224 S2P 0.9176
225 SHI 0.9175
226 1VK 0.9175
227 A9P 0.9174
228 SLS 0.9171
229 MPK 0.9166
230 HHH 0.9165
231 DHC 0.9164
232 1XA 0.9162
233 36M 0.9161
234 ABI 0.9161
235 FF2 0.9160
236 P7Y 0.9160
237 DZA 0.9159
238 D2G 0.9159
239 6RQ 0.9158
240 HF2 0.9156
241 4NB 0.9156
242 ONR 0.9155
243 3R4 0.9155
244 8OZ 0.9154
245 94W 0.9153
246 H4E 0.9152
247 3NY 0.9152
248 3QV 0.9150
249 9R5 0.9150
250 N1E 0.9149
251 AL0 0.9149
252 PRA 0.9148
253 KMY 0.9146
254 ANN 0.9146
255 I3E 0.9145
256 K97 0.9145
257 5WZ 0.9143
258 TYC 0.9142
259 JG8 0.9142
260 DIR 0.9141
261 4FF 0.9141
262 L99 0.9141
263 F9P 0.9141
264 069 0.9140
265 4I8 0.9138
266 3QM 0.9137
267 8XL 0.9136
268 5NI 0.9136
269 DTY 0.9134
270 M3E 0.9133
271 FMQ 0.9133
272 HGA 0.9132
273 SQ7 0.9130
274 C0H 0.9130
275 2HU 0.9129
276 GJZ 0.9127
277 LSQ 0.9127
278 RNO 0.9126
279 QMP 0.9125
280 49F 0.9121
281 258 0.9119
282 5XC 0.9118
283 78Y 0.9117
284 TPA 0.9116
285 NYL 0.9114
286 TZM 0.9113
287 PFF 0.9113
288 SN4 0.9113
289 PBN 0.9112
290 E7S 0.9108
291 K80 0.9108
292 0F9 0.9106
293 TB8 0.9103
294 JMG 0.9102
295 PCS 0.9100
296 1HN 0.9098
297 CWJ 0.9095
298 A5H 0.9095
299 GCO 0.9094
300 7MU 0.9094
301 K2T 0.9092
302 2HG 0.9088
303 6QF 0.9088
304 3PF 0.9087
305 GF4 0.9085
306 FBB 0.9082
307 FDR 0.9081
308 8D6 0.9081
309 2IT 0.9081
310 DGL 0.9081
311 152 0.9080
312 EVF 0.9080
313 2FX 0.9080
314 EXD 0.9076
315 INO 0.9075
316 ANC 0.9072
317 D48 0.9072
318 X6W 0.9071
319 0W1 0.9070
320 J9T 0.9070
321 GLO 0.9068
322 HA5 0.9068
323 SNO 0.9067
324 LPK 0.9064
325 4NM 0.9064
326 DGN 0.9063
327 6ZX 0.9063
328 GJP 0.9062
329 CXH 0.9062
330 JDN 0.9059
331 FEH 0.9058
332 80G 0.9057
333 SQV 0.9057
334 7BC 0.9056
335 EQW 0.9049
336 UN1 0.9048
337 6HO 0.9046
338 4RU 0.9045
339 8U3 0.9044
340 M1Z 0.9043
341 RKV 0.9039
342 K4V 0.9038
343 J5I 0.9038
344 KJU 0.9038
345 G3E 0.9037
346 KLE 0.9037
347 12T 0.9036
348 KDG 0.9035
349 ASC 0.9035
350 OKG 0.9034
351 MTL 0.9030
352 PHB 0.9030
353 ERZ 0.9029
354 8NB 0.9029
355 6Q3 0.9028
356 ZYR 0.9026
357 SE2 0.9026
358 SYV 0.9026
359 QIV 0.9025
360 5GU 0.9025
361 GLU 0.9023
362 SOR 0.9021
363 A7H 0.9021
364 ES2 0.9020
365 HPS 0.9020
366 FCD 0.9018
367 30G 0.9018
368 4BF 0.9017
369 DEW 0.9017
370 TAG 0.9016
371 BRH 0.9015
372 YPN 0.9014
373 11C 0.9013
374 45L 0.9013
375 0VT 0.9013
376 RAT 0.9011
377 5TY 0.9010
378 3VS 0.9010
379 EGR 0.9009
380 DDU 0.9009
381 Y3L 0.9009
382 H42 0.9008
383 LJ3 0.9008
384 FUD 0.9006
385 5OB 0.9006
386 ZME 0.9006
387 B85 0.9005
388 R9Y 0.9005
389 N8Y 0.9004
390 GLN 0.9003
391 5H6 0.9003
392 GNW 0.9003
393 344 0.9003
394 X11 0.9001
395 9FH 0.9000
396 PAB 0.8999
397 Z70 0.8999
398 BZ3 0.8999
399 LGT 0.8997
400 7UZ 0.8997
401 IAC 0.8994
402 1X4 0.8994
403 3HG 0.8992
404 LZ5 0.8991
405 COU 0.8990
406 1P8 0.8990
407 CLW 0.8990
408 SYC 0.8988
409 4JT 0.8988
410 3PG 0.8985
411 HG3 0.8985
412 03V 0.8984
413 2HQ 0.8984
414 LO1 0.8983
415 GZL 0.8982
416 JB5 0.8982
417 MXD 0.8982
418 2D2 0.8981
419 GWM 0.8980
420 4FP 0.8980
421 3VW 0.8980
422 MAH 0.8980
423 6MW 0.8977
424 PKU 0.8977
425 S7A 0.8976
426 2BX 0.8975
427 LLH 0.8975
428 0K7 0.8974
429 CS2 0.8974
430 F16 0.8973
431 AHN 0.8973
432 SD4 0.8972
433 3VX 0.8972
434 PBA 0.8971
435 OEG 0.8971
436 KTA 0.8971
437 ES5 0.8970
438 VGD 0.8970
439 PHI 0.8970
440 2PK 0.8970
441 DAH 0.8970
442 TOH 0.8969
443 JCZ 0.8969
444 ET2 0.8969
445 S0E 0.8969
446 GB5 0.8963
447 NPO 0.8962
448 HRM 0.8961
449 JB8 0.8960
450 OCH 0.8960
451 2AQ 0.8960
452 P72 0.8958
453 Q06 0.8958
454 S0W 0.8957
455 PBZ 0.8956
456 KYN 0.8955
457 B2Y 0.8955
458 PEY 0.8954
459 FTV 0.8952
460 BEA 0.8952
461 CUW 0.8952
462 LR5 0.8952
463 CFA 0.8952
464 JLZ 0.8951
465 8WO 0.8949
466 DHB 0.8949
467 2FY 0.8948
468 2PV 0.8946
469 2HO 0.8946
470 MEQ 0.8945
471 2FQ 0.8942
472 VXX 0.8942
473 717 0.8942
474 4FS 0.8940
475 9UL 0.8939
476 93K 0.8939
477 HBO 0.8937
478 OOG 0.8936
479 GUA 0.8936
480 ITE 0.8935
481 3AE 0.8935
482 5OO 0.8933
483 1BN 0.8933
484 36R 0.8933
485 SSB 0.8933
486 MS9 0.8932
487 650 0.8932
488 S7J 0.8931
489 DRG 0.8930
490 N91 0.8930
491 M5E 0.8928
492 IOS 0.8928
493 8HC 0.8927
494 S7S 0.8926
495 S0D 0.8926
496 KMH 0.8922
497 LVD 0.8922
498 68A 0.8921
499 AX3 0.8921
500 8NX 0.8920
501 M5H 0.8919
502 AA 0.8919
503 C2Y 0.8919
504 ZEC 0.8919
505 92P 0.8919
506 0FR 0.8918
507 P9P 0.8917
508 CCU 0.8917
509 AMQ 0.8917
510 ANF 0.8917
511 4TB 0.8915
512 A7N 0.8915
513 AEG 0.8914
514 SHA 0.8913
515 9FG 0.8912
516 0FK 0.8912
517 THU 0.8912
518 FBF 0.8911
519 M4N 0.8910
520 OK7 0.8909
521 TJM 0.8908
522 BIK 0.8908
523 MAJ 0.8908
524 F9Y 0.8906
525 BPN 0.8906
526 XRG 0.8906
527 XI7 0.8905
528 PRL 0.8904
529 OQC 0.8904
530 FQX 0.8903
531 2FT 0.8903
532 7ZL 0.8902
533 AY4 0.8900
534 PZI 0.8900
535 MMJ 0.8898
536 4FA 0.8897
537 7R4 0.8896
538 HBD 0.8896
539 EQA 0.8894
540 ATX 0.8892
541 4NC 0.8892
542 IHB 0.8890
543 8WT 0.8890
544 M4E 0.8890
545 A3M 0.8890
546 JA8 0.8889
547 27B 0.8889
548 E0O 0.8888
549 5GT 0.8887
550 W29 0.8887
551 Q04 0.8886
552 9FE 0.8885
553 1Y6 0.8885
554 AJY 0.8883
555 9ON 0.8882
556 RP3 0.8882
557 GGL 0.8881
558 92K 0.8881
559 GOE 0.8880
560 8CC 0.8879
561 THA 0.8877
562 2O6 0.8877
563 ARG 0.8877
564 V1T 0.8875
565 M4S 0.8874
566 GLY GLY 0.8874
567 4MA 0.8873
568 5VM 0.8872
569 F2W 0.8871
570 4G2 0.8870
571 NNO 0.8870
572 2B4 0.8866
573 Z5P 0.8866
574 SKF 0.8866
575 ZYQ 0.8865
576 9TW 0.8865
577 D8Q 0.8864
578 LYS 0.8862
579 ABV 0.8862
580 4VY 0.8862
581 AAN 0.8861
582 B21 0.8860
583 86J 0.8860
584 IYR 0.8859
585 EYJ 0.8859
586 259 0.8856
587 BZQ 0.8855
588 AC6 0.8854
589 4NZ 0.8853
590 QSB 0.8853
591 LEL 0.8851
592 F69 0.8850
593 LFC 0.8848
594 MYJ 0.8846
595 K7H 0.8845
596 HNT 0.8843
597 BGU 0.8842
598 NK5 0.8842
599 1PS 0.8840
600 TZL 0.8840
601 8W9 0.8839
602 KW8 0.8839
603 SV4 0.8838
604 AJV 0.8838
605 GOJ 0.8838
606 Y4L 0.8838
607 TSU 0.8837
608 SAF 0.8836
609 E4P 0.8836
610 FHB 0.8835
611 KLS 0.8834
612 SMN 0.8834
613 GO8 0.8833
614 1KN 0.8831
615 3C5 0.8830
616 K3D 0.8829
617 N0Z 0.8829
618 LT1 0.8828
619 VM1 0.8826
620 ALA ALA 0.8825
621 N4E 0.8825
622 Q02 0.8824
623 28A 0.8822
624 3ID 0.8821
625 4A3 0.8820
626 KUF 0.8820
627 DIN 0.8820
628 PEA 0.8819
629 GNM 0.8819
630 0LO 0.8818
631 9BF 0.8817
632 5F8 0.8817
633 B4O 0.8816
634 DHY 0.8816
635 463 0.8814
636 7Q1 0.8813
637 YRL 0.8812
638 39O 0.8812
639 833 0.8812
640 JBZ 0.8812
641 SW7 0.8812
642 R9J 0.8811
643 BTM 0.8811
644 GRO 0.8811
645 S60 0.8810
646 7MX 0.8808
647 OA1 0.8807
648 VC3 0.8807
649 EWG 0.8806
650 SSC 0.8806
651 APG 0.8806
652 SOJ 0.8806
653 JGB 0.8804
654 6J5 0.8803
655 DAL DAL 0.8803
656 SEP 0.8802
657 5FL 0.8802
658 TTL 0.8802
659 13P 0.8802
660 505 0.8800
661 QME 0.8797
662 5F5 0.8796
663 PMF 0.8796
664 QBS 0.8795
665 DMD 0.8795
666 ONH 0.8794
667 L1T 0.8793
668 DUR 0.8792
669 TIA 0.8792
670 RMN 0.8792
671 49O 0.8791
672 AX7 0.8790
673 NDH 0.8790
674 ODO 0.8789
675 X0V 0.8789
676 XX2 0.8787
677 CHB 0.8784
678 CXF 0.8783
679 LT2 0.8782
680 MD6 0.8781
681 QY9 0.8781
682 DQU 0.8780
683 SYM 0.8780
684 826 0.8780
685 LDP 0.8779
686 EUE 0.8778
687 DCZ 0.8778
688 3HM 0.8778
689 LR8 0.8777
690 6ME 0.8777
691 7MW 0.8777
692 HJ7 0.8777
693 L15 0.8774
694 AVA 0.8773
695 HNM 0.8773
696 D1G 0.8772
697 YIE 0.8772
698 DHR 0.8771
699 OTW 0.8771
700 1XS 0.8771
701 5XB 0.8769
702 N2M 0.8765
703 IPO 0.8764
704 LL1 0.8763
705 Z82 0.8762
706 PQS 0.8760
707 NF3 0.8759
708 PH2 0.8759
709 GGB 0.8756
710 5E5 0.8756
711 MRW 0.8754
712 URS 0.8752
713 2K8 0.8752
714 SKA 0.8752
715 IV2 0.8751
716 5WV 0.8751
717 B62 0.8751
718 TRP 0.8751
719 EA1 0.8750
720 2MI 0.8750
721 HSX 0.8750
722 QX4 0.8746
723 MR1 0.8745
724 4MU 0.8742
725 1ZC 0.8741
726 ZHA 0.8740
727 5TT 0.8740
728 IFP 0.8739
729 FCR 0.8739
730 FC2 0.8739
731 9RH 0.8739
732 JP2 0.8738
733 AMS 0.8738
734 OAA 0.8735
735 I3A 0.8734
736 AES 0.8734
737 XRX 0.8733
738 YE6 0.8732
739 4JC 0.8732
740 BSA 0.8731
741 CTL 0.8731
742 HHS 0.8731
743 XHP 0.8728
744 CCD 0.8728
745 OVM 0.8727
746 FAN 0.8724
747 NAG 0.8723
748 GPF 0.8723
749 MMS 0.8722
750 4SX 0.8722
751 AVI 0.8721
752 SME 0.8720
753 PD2 0.8720
754 CCE 0.8719
755 5RO 0.8719
756 PGH 0.8717
757 9NB 0.8717
758 5QX 0.8716
759 5TZ 0.8715
760 AEF 0.8713
761 HHR 0.8712
762 PRZ 0.8712
763 4FH 0.8710
764 174 0.8710
765 DNF 0.8709
766 DHM 0.8708
767 0P6 0.8708
768 0SY 0.8707
769 0UL 0.8706
770 F31 0.8705
771 2UB 0.8704
772 3QO 0.8703
773 MVN 0.8702
774 GPJ 0.8701
775 9RW 0.8700
776 MUK 0.8699
777 6J9 0.8697
778 MLT 0.8697
779 A7W 0.8697
780 5GV 0.8697
781 535 0.8696
782 3J8 0.8695
783 6L6 0.8695
784 HQT 0.8694
785 44W 0.8693
786 ZBT 0.8689
787 AMR 0.8688
788 ES7 0.8688
789 4TU 0.8687
790 0XT 0.8687
791 DPT 0.8685
792 SRO 0.8683
793 DOB 0.8680
794 CLZ 0.8680
795 TWO 0.8680
796 FBS 0.8679
797 SAN 0.8679
798 F06 0.8678
799 I2E 0.8678
800 0N7 0.8678
801 ROI 0.8678
802 A51 0.8678
803 G3H 0.8675
804 GP9 0.8675
805 12Q 0.8675
806 HQD 0.8674
807 A98 0.8672
808 H5B 0.8672
809 QMR 0.8672
810 42J 0.8672
811 G3P 0.8671
812 CWS 0.8670
813 44V 0.8670
814 FUM 0.8670
815 TCR 0.8668
816 4NS 0.8667
817 VNL 0.8667
818 P9E 0.8665
819 4J8 0.8665
820 BHA 0.8665
821 ICO 0.8664
822 4CM 0.8664
823 4ME 0.8663
824 ZRK 0.8661
825 60L 0.8660
826 0FO 0.8660
827 4AA 0.8659
828 YTX 0.8656
829 XRS 0.8656
830 KKN 0.8655
831 GB4 0.8654
832 SKM 0.8653
833 BEZ 0.8651
834 EKZ 0.8651
835 270 0.8651
836 XM0 0.8651
837 DX3 0.8650
838 2AL 0.8650
839 KYA 0.8650
840 B2T 0.8650
841 RP5 0.8649
842 OW4 0.8648
843 AAS 0.8648
844 AUV 0.8645
845 LTL 0.8645
846 3AL 0.8644
847 STX 0.8643
848 K48 0.8643
849 27K 0.8640
850 WOE 0.8639
851 5RN 0.8639
852 CSN 0.8638
853 KT7 0.8638
854 DE3 0.8638
855 6P3 0.8638
856 PQM 0.8638
857 5O6 0.8636
858 JAE 0.8636
859 7W1 0.8634
860 CC5 0.8633
861 549 0.8627
862 URC 0.8626
863 MHN 0.8625
864 N7I 0.8625
865 TH7 0.8625
866 P92 0.8624
867 4MB 0.8622
868 0OC 0.8621
869 7ME 0.8621
870 3Z8 0.8620
871 MNN 0.8620
872 TSS 0.8620
873 FQI 0.8619
874 OMD 0.8619
875 3S5 0.8619
876 M78 0.8617
877 UFO 0.8616
878 D9Z 0.8614
879 8CM 0.8613
880 GDE 0.8610
881 ISN 0.8610
882 MOK 0.8609
883 3OM 0.8607
884 4LR 0.8605
885 BVS 0.8605
886 1SA 0.8601
887 MSL 0.8600
888 XQ0 0.8600
889 H4B 0.8600
890 AG2 0.8600
891 LFQ 0.8599
892 4AU 0.8599
893 M2K 0.8598
894 A9B 0.8595
895 FA0 0.8594
896 GAB 0.8594
897 Q4G 0.8591
898 23J 0.8591
899 AZ9 0.8590
900 FER 0.8590
901 6VD 0.8588
902 DEE 0.8587
903 PLP 0.8587
904 PEP 0.8583
905 CLU 0.8581
906 9GB 0.8580
907 DNA 0.8578
908 QBP 0.8576
909 FYR 0.8575
910 QSH 0.8575
911 ORN 0.8575
912 STT 0.8573
913 2AK 0.8572
914 SIN 0.8572
915 J9W 0.8571
916 LMR 0.8568
917 BPU 0.8566
918 X1R 0.8561
919 M1Q 0.8560
920 DXP 0.8558
921 0FN 0.8556
922 4HC 0.8556
923 XAZ 0.8553
924 4M0 0.8550
925 3Y7 0.8548
926 2WU 0.8540
927 11S 0.8540
928 2GD 0.8537
929 F60 0.8533
930 AZM 0.8529
931 3XH 0.8523
932 HWD 0.8523
933 6DP 0.8519
934 R8V 0.8517
935 55D 0.8515
936 FP1 0.8512
937 SNV 0.8512
938 8MO 0.8512
Ligand no: 2; Ligand: AX7; Similar ligands found: 1307
No: Ligand Similarity coefficient
1 270 1.0000
2 2MI 1.0000
3 GLY GLY 1.0000
4 ABV 0.9998
5 P92 0.9994
6 XM0 0.9924
7 1PT 0.9892
8 5WV 0.9797
9 BZX 0.9790
10 NPO 0.9790
11 LZ1 0.9760
12 03V 0.9760
13 Q88 0.9759
14 ES0 0.9757
15 DEN 0.9756
16 CWM 0.9755
17 PHB 0.9753
18 0R1 0.9748
19 BZI 0.9748
20 MPI 0.9745
21 QUZ 0.9743
22 IND 0.9739
23 NPY 0.9738
24 COU 0.9732
25 JAE 0.9727
26 4FS 0.9727
27 BEZ 0.9727
28 14O 0.9722
29 F60 0.9721
30 5H1 0.9717
31 BAM 0.9716
32 FBB 0.9715
33 PEA 0.9714
34 BZF 0.9713
35 6AI 0.9713
36 BEN 0.9711
37 NCA 0.9711
38 36R 0.9710
39 ISN 0.9710
40 HBD 0.9707
41 5MI 0.9706
42 5VM 0.9705
43 JB5 0.9703
44 0CT 0.9702
45 CLW 0.9701
46 ES5 0.9701
47 GVH 0.9699
48 4JP 0.9699
49 ES7 0.9693
50 2K4 0.9692
51 H42 0.9692
52 2AQ 0.9687
53 5MB 0.9686
54 XIY 0.9685
55 1P8 0.9682
56 K2T 0.9680
57 6PC 0.9680
58 7W4 0.9675
59 ES2 0.9671
60 KKN 0.9661
61 717 0.9661
62 11S 0.9653
63 PAB 0.9650
64 3ID 0.9648
65 NTN 0.9648
66 YCP 0.9646
67 NIO 0.9643
68 4XR 0.9643
69 IDM 0.9642
70 NIZ 0.9640
71 AHR 0.9640
72 1Y6 0.9638
73 OCH 0.9637
74 XQ0 0.9636
75 2CK 0.9630
76 ES9 0.9627
77 5XC 0.9618
78 KOJ 0.9616
79 PBZ 0.9613
80 2D0 0.9608
81 4MA 0.9605
82 H4N 0.9602
83 VGL 0.9600
84 FK1 0.9597
85 ISZ 0.9596
86 RSO 0.9596
87 NBZ 0.9595
88 826 0.9594
89 HBA 0.9593
90 174 0.9592
91 DMD 0.9587
92 P72 0.9582
93 FYU 0.9579
94 BZ3 0.9579
95 173 0.9575
96 GLC 0.9574
97 5OB 0.9573
98 TH7 0.9569
99 8ZE 0.9567
100 FPI 0.9567
101 HMH 0.9564
102 DOB 0.9560
103 2BG 0.9559
104 BHA 0.9557
105 FA0 0.9555
106 H8N 0.9554
107 4M0 0.9554
108 JA8 0.9554
109 Z82 0.9554
110 AMC 0.9554
111 BHO 0.9553
112 5NU 0.9550
113 JZ9 0.9550
114 CFI 0.9546
115 5CU 0.9542
116 UNU 0.9542
117 A7W 0.9540
118 I1E 0.9539
119 BE7 0.9537
120 XYP 0.9534
121 PHU 0.9530
122 AC0 0.9528
123 3PF 0.9527
124 4P5 0.9523
125 BGC 0.9521
126 9EW 0.9520
127 DHB 0.9520
128 M1A 0.9519
129 67N 0.9517
130 PZA 0.9517
131 6RQ 0.9514
132 1MC 0.9514
133 1SQ 0.9513
134 4FA 0.9513
135 5SG 0.9512
136 DIN 0.9509
137 MCT 0.9509
138 0RW 0.9508
139 FAN 0.9506
140 MRW 0.9506
141 SAL 0.9506
142 5IQ 0.9504
143 1LQ 0.9501
144 M4T 0.9500
145 NK 0.9499
146 HPA 0.9497
147 F05 0.9496
148 8NY 0.9495
149 N5J 0.9494
150 ADE 0.9494
151 6M9 0.9494
152 OAA 0.9493
153 LXC 0.9491
154 SVN 0.9490
155 5Q0 0.9489
156 TH0 0.9485
157 PBC 0.9485
158 TTL 0.9483
159 TPA 0.9483
160 HQY 0.9482
161 4YS 0.9481
162 ES1 0.9480
163 URC 0.9480
164 URF 0.9475
165 24W 0.9475
166 JPZ 0.9472
167 OK7 0.9470
168 4HO 0.9469
169 10L 0.9467
170 1DW 0.9467
171 1NP 0.9467
172 PZI 0.9467
173 HLR 0.9466
174 BE2 0.9466
175 FBM 0.9466
176 SS1 0.9466
177 4JU 0.9462
178 4VP 0.9461
179 F9P 0.9461
180 NOJ 0.9460
181 WBU 0.9458
182 6M4 0.9458
183 SYV 0.9457
184 4JT 0.9457
185 TDR 0.9456
186 12Q 0.9454
187 8GC 0.9453
188 MWM 0.9451
189 5QY 0.9450
190 CTL 0.9445
191 KJH 0.9444
192 PXL 0.9444
193 BSX 0.9443
194 275 0.9442
195 JLZ 0.9440
196 4CS 0.9439
197 F9Y 0.9438
198 R8V 0.9436
199 4NC 0.9435
200 86J 0.9431
201 7W1 0.9431
202 4JQ 0.9431
203 ICP 0.9430
204 PYD 0.9430
205 HBX 0.9429
206 I3A 0.9428
207 XBZ 0.9428
208 54D 0.9427
209 MQN 0.9427
210 XX2 0.9426
211 INO 0.9425
212 K34 0.9424
213 4BZ 0.9424
214 QWN 0.9422
215 9DA 0.9421
216 PRO 0.9421
217 2AC 0.9420
218 8H8 0.9420
219 4SV 0.9420
220 2MH 0.9420
221 4ZE 0.9419
222 AC6 0.9417
223 MZG 0.9417
224 BTY 0.9415
225 XYD 0.9412
226 JBE 0.9411
227 G3E 0.9411
228 3AB 0.9411
229 5QX 0.9410
230 SYN 0.9410
231 7HP 0.9409
232 5JQ 0.9409
233 1P7 0.9409
234 282 0.9408
235 GAB 0.9407
236 4CL 0.9405
237 NBE 0.9405
238 MR1 0.9405
239 3NT 0.9402
240 P9P 0.9402
241 7WA 0.9400
242 BPN 0.9400
243 5UC 0.9396
244 3HB 0.9396
245 2MP 0.9395
246 PYF 0.9395
247 J1Z 0.9394
248 4JJ 0.9394
249 2HO 0.9394
250 9HX 0.9393
251 34A 0.9393
252 3U4 0.9393
253 8WT 0.9393
254 E5X 0.9393
255 7HQ 0.9392
256 SW7 0.9392
257 BP1 0.9391
258 4XH 0.9391
259 DE5 0.9391
260 FHB 0.9387
261 HH8 0.9386
262 6MP 0.9385
263 NNO 0.9385
264 HQT 0.9385
265 2HQ 0.9385
266 5JC 0.9384
267 75K 0.9383
268 FOA 0.9383
269 BZ2 0.9382
270 5HN 0.9381
271 5MH 0.9381
272 MYJ 0.9378
273 JZ2 0.9377
274 JZ3 0.9377
275 RSF 0.9377
276 D48 0.9376
277 PM6 0.9375
278 J6W 0.9375
279 A1U 0.9374
280 PIM 0.9374
281 HIS 0.9374
282 ABN 0.9373
283 LG4 0.9371
284 PLQ 0.9370
285 B55 0.9370
286 ES4 0.9370
287 IV2 0.9370
288 3OC 0.9370
289 23A 0.9369
290 CXF 0.9369
291 3HM 0.9368
292 KDV 0.9368
293 HQE 0.9367
294 3HA 0.9367
295 4A3 0.9366
296 0P6 0.9366
297 8TX 0.9362
298 YRL 0.9362
299 3F0 0.9362
300 261 0.9362
301 PY7 0.9361
302 BR9 0.9359
303 93K 0.9358
304 ES6 0.9358
305 27Y 0.9358
306 CWS 0.9357
307 ICB 0.9357
308 2YU 0.9357
309 XAZ 0.9355
310 J9Q 0.9355
311 O72 0.9354
312 B57 0.9354
313 KUF 0.9354
314 FPN 0.9353
315 4WL 0.9353
316 PCR 0.9352
317 EA1 0.9350
318 4ZA 0.9349
319 5B1 0.9347
320 PAC 0.9346
321 QXW 0.9345
322 ESP 0.9345
323 92K 0.9344
324 PXY 0.9343
325 MWJ 0.9342
326 0TU 0.9341
327 FPY 0.9340
328 BML 0.9339
329 DA1 0.9337
330 N2I 0.9337
331 5JL 0.9335
332 SE2 0.9332
333 TM7 0.9332
334 53C 0.9331
335 PBA 0.9330
336 FBA 0.9329
337 FP1 0.9327
338 6FZ 0.9326
339 MLT 0.9323
340 25R 0.9322
341 QSC 0.9320
342 SKA 0.9320
343 JBH 0.9319
344 ANN 0.9318
345 0JD 0.9318
346 JBK 0.9317
347 DBH 0.9317
348 ADZ 0.9317
349 HT4 0.9316
350 43M 0.9314
351 JKE 0.9314
352 HH5 0.9314
353 SOE 0.9314
354 MS9 0.9312
355 RM1 0.9312
356 BTE 0.9311
357 FE DB1 0.9311
358 J5I 0.9309
359 0R0 0.9308
360 PYC 0.9306
361 4CH 0.9304
362 3M0 0.9303
363 4YO 0.9302
364 1LM 0.9301
365 97T 0.9301
366 9TW 0.9300
367 GUN 0.9300
368 8CM 0.9299
369 OVV 0.9299
370 WCE 0.9298
371 G3F 0.9298
372 7MU 0.9294
373 4HS 0.9293
374 3XX 0.9293
375 82I 0.9292
376 0HN 0.9292
377 4JL 0.9292
378 NMJ 0.9291
379 SHA 0.9290
380 E7S 0.9290
381 TP5 0.9289
382 PIY 0.9289
383 AZA 0.9288
384 FUL 0.9285
385 P3K 0.9284
386 GCS 0.9284
387 HX3 0.9282
388 1WD 0.9281
389 CHB 0.9281
390 C2B 0.9280
391 SWA 0.9279
392 9DG 0.9278
393 FQI 0.9277
394 ESX 0.9275
395 XYS 0.9274
396 HDH 0.9272
397 KJU 0.9272
398 1MR 0.9270
399 5RG 0.9269
400 OXQ 0.9267
401 7WV 0.9265
402 6GU 0.9264
403 8IG 0.9262
404 GAL 0.9261
405 CFP 0.9260
406 DHR 0.9258
407 R9Y 0.9257
408 KT7 0.9256
409 GBD 0.9255
410 XAN 0.9255
411 0HO 0.9255
412 TYL 0.9255
413 9R5 0.9255
414 5RN 0.9251
415 IPB 0.9250
416 M58 0.9249
417 069 0.9247
418 NSP 0.9247
419 2FY 0.9246
420 TZC 0.9246
421 4JN 0.9245
422 RIP 0.9244
423 UGC 0.9242
424 JZ7 0.9242
425 WOT 0.9240
426 4HM 0.9240
427 TIU 0.9239
428 265 0.9238
429 14J 0.9238
430 MAE 0.9238
431 A2F 0.9237
432 6AP 0.9236
433 G2F 0.9235
434 3BZ 0.9234
435 BRT 0.9233
436 4JO 0.9230
437 94W 0.9230
438 LDP 0.9230
439 SAN 0.9230
440 5NI 0.9229
441 DFB 0.9229
442 C21 0.9228
443 DGJ 0.9228
444 DX4 0.9226
445 IGA 0.9226
446 8S0 0.9226
447 PNZ 0.9224
448 N8Y 0.9222
449 6NT 0.9222
450 2PC 0.9222
451 M2K 0.9221
452 0TR 0.9220
453 JIF 0.9220
454 1F1 0.9216
455 AZ8 0.9215
456 0MK 0.9214
457 PCA 0.9214
458 2HU 0.9212
459 4AA 0.9211
460 4JM 0.9211
461 VNJ 0.9210
462 3SK 0.9210
463 FDB 0.9208
464 JZ5 0.9204
465 FUC 0.9204
466 BEA 0.9203
467 GDE 0.9203
468 BCU 0.9202
469 FCR 0.9201
470 IFL 0.9201
471 ASO 0.9200
472 GAG 0.9200
473 HIO 0.9200
474 TGX 0.9200
475 2EC 0.9200
476 HMU 0.9199
477 SRT 0.9198
478 0CU 0.9197
479 DHK 0.9197
480 5GU 0.9196
481 HY1 0.9195
482 A29 0.9194
483 DYA 0.9194
484 IF7 0.9193
485 CWJ 0.9192
486 L3Q 0.9191
487 141 0.9189
488 7B4 0.9189
489 IHB 0.9189
490 AZG 0.9189
491 ZZT 0.9188
492 IT2 0.9188
493 JAW 0.9187
494 XBT 0.9187
495 6F0 0.9186
496 IUR 0.9185
497 AZ9 0.9185
498 273 0.9185
499 3A9 0.9183
500 XRG 0.9183
501 QOS 0.9183
502 IOL 0.9183
503 LT2 0.9183
504 YH7 0.9182
505 GTQ 0.9182
506 3NY 0.9182
507 Q24 0.9180
508 NDH 0.9180
509 2ZM 0.9179
510 ZBT 0.9179
511 R8S 0.9177
512 HSM 0.9177
513 JBN 0.9176
514 GZL 0.9176
515 GRE 0.9174
516 B53 0.9174
517 1DU 0.9174
518 24B 0.9173
519 ABI 0.9170
520 8OZ 0.9170
521 HHA 0.9169
522 BNF 0.9167
523 IDH 0.9167
524 TLA 0.9166
525 PEL 0.9165
526 EQT 0.9163
527 6NI 0.9163
528 9FL 0.9163
529 MSR 0.9163
530 E7Z 0.9161
531 FEH 0.9161
532 5M0 0.9161
533 1XN 0.9161
534 AEF 0.9160
535 3DM 0.9160
536 3Z8 0.9160
537 Y8I 0.9159
538 QSB 0.9158
539 PKU 0.9158
540 2ZV 0.9156
541 6M1 0.9156
542 6CS 0.9156
543 LDU 0.9156
544 7N0 0.9155
545 M1Q 0.9155
546 EUG 0.9153
547 JFJ 0.9153
548 RMN 0.9152
549 5AC 0.9150
550 ICO 0.9150
551 0FN 0.9149
552 PZM 0.9149
553 TSU 0.9148
554 F81 0.9147
555 54G 0.9147
556 SWD 0.9144
557 AKG 0.9144
558 MUA 0.9142
559 MEW 0.9141
560 4NM 0.9140
561 150 0.9140
562 290 0.9139
563 JAB 0.9139
564 RIB 0.9139
565 1XM 0.9138
566 R8A 0.9138
567 M6W 0.9137
568 1WG 0.9135
569 52C 0.9135
570 F0J 0.9134
571 GIO 0.9132
572 TLD 0.9131
573 ARB 0.9131
574 2FG 0.9130
575 GYE 0.9130
576 M5K 0.9129
577 M6N 0.9129
578 9CL 0.9128
579 7WG 0.9128
580 2LP 0.9126
581 2AL 0.9126
582 R9S 0.9124
583 JDN 0.9123
584 AQO 0.9122
585 LZM 0.9122
586 V55 0.9121
587 8WO 0.9121
588 4HC 0.9120
589 PE0 0.9119
590 3WA 0.9118
591 FB2 0.9118
592 AJ2 0.9116
593 AAS 0.9115
594 GLL 0.9113
595 HY3 0.9113
596 SKM 0.9113
597 CRS 0.9113
598 JBQ 0.9111
599 UY7 0.9111
600 LMR 0.9110
601 BOA 0.9110
602 OTR 0.9110
603 EKZ 0.9110
604 HQJ 0.9110
605 60P 0.9109
606 42A 0.9109
607 2CQ 0.9106
608 KPL 0.9105
609 AGK 0.9104
610 OHG 0.9104
611 9CA 0.9103
612 259 0.9102
613 0W8 0.9102
614 5RO 0.9102
615 DFU 0.9102
616 GJZ 0.9102
617 15N 0.9102
618 268 0.9100
619 2A9 0.9100
620 9TZ 0.9100
621 J9W 0.9099
622 M3H 0.9099
623 GUA 0.9099
624 4ME 0.9098
625 7MH 0.9096
626 23W 0.9096
627 BCP 0.9094
628 2H5 0.9094
629 42J 0.9093
630 SN4 0.9092
631 RHU 0.9091
632 BDP 0.9091
633 ECE 0.9091
634 GIF 0.9090
635 NOY 0.9090
636 1DV 0.9088
637 RCO 0.9087
638 15E 0.9084
639 APZ 0.9083
640 ADK 0.9083
641 IFP 0.9082
642 GLA 0.9082
643 1IT 0.9080
644 HQD 0.9079
645 51R 0.9079
646 ORO 0.9078
647 7CZ 0.9075
648 T6C 0.9075
649 149 0.9074
650 64K 0.9074
651 G4D 0.9073
652 4ZC 0.9072
653 PYJ 0.9071
654 J9N 0.9069
655 3ZQ 0.9069
656 5MK 0.9068
657 BNS 0.9067
658 VNL 0.9066
659 FA1 0.9065
660 GAF 0.9064
661 264 0.9063
662 MAK 0.9061
663 QY9 0.9061
664 DHQ 0.9061
665 6TZ 0.9061
666 L5V 0.9059
667 APY 0.9059
668 4J8 0.9057
669 TFB 0.9057
670 DOR 0.9056
671 MT0 0.9054
672 ASP 0.9052
673 OGA 0.9051
674 286 0.9050
675 42C 0.9050
676 SS2 0.9050
677 B24 0.9050
678 4Z4 0.9049
679 AZF 0.9049
680 3CH 0.9048
681 ESI 0.9047
682 OTW 0.9046
683 B62 0.9046
684 URA 0.9046
685 LG3 0.9045
686 GCU 0.9045
687 AMH 0.9044
688 CEE 0.9043
689 URP 0.9043
690 G6D 0.9042
691 258 0.9040
692 QMP 0.9040
693 FBS 0.9040
694 XHP 0.9038
695 BP9 0.9038
696 OXC 0.9038
697 CYT 0.9037
698 LCN 0.9035
699 TSS 0.9035
700 GIV 0.9035
701 S76 0.9034
702 JFD 0.9033
703 32X 0.9033
704 HZQ 0.9033
705 FGZ 0.9033
706 1P3 0.9032
707 PRA 0.9032
708 7NI 0.9031
709 FCA 0.9030
710 J9T 0.9030
711 QWW 0.9029
712 E1T 0.9026
713 PHE 0.9026
714 XQG 0.9025
715 3FH 0.9025
716 DQU 0.9023
717 IFM 0.9023
718 25W 0.9020
719 Q6T 0.9018
720 PMB 0.9018
721 SMV 0.9017
722 0N7 0.9017
723 HC4 0.9016
724 X0V 0.9014
725 0FO 0.9014
726 F31 0.9014
727 45L 0.9013
728 TAR 0.9013
729 SX1 0.9012
730 PYG 0.9012
731 KIV 0.9011
732 G5V 0.9010
733 RB5 0.9006
734 285 0.9004
735 AX3 0.9004
736 MWP 0.9003
737 CAQ 0.9003
738 SNU 0.9002
739 X6X 0.9002
740 2A7 0.9001
741 428 0.8999
742 D1X 0.8999
743 L99 0.8998
744 M1E 0.8997
745 SJ5 0.8997
746 495 0.8996
747 5LA 0.8996
748 DHS 0.8996
749 FBW 0.8996
750 C2A 0.8995
751 UNJ 0.8994
752 KJY 0.8994
753 4MU 0.8994
754 44W 0.8993
755 R2B 0.8993
756 3MC 0.8993
757 1SA 0.8993
758 TEP 0.8992
759 92P 0.8992
760 4XV 0.8991
761 HPS 0.8991
762