Receptor
PDB id Resolution Class Description Source Keywords
6MQF 1.69 Å EC: 3.1.1.4 MYOTOXIN II FROM BOTHROPS MOOJENI COMPLEXED WITH ACETYLSALIC BOTHROPS MOOJENI ASPIRIN ACETYLSALICYLIC ACID TOXIN
Ref.: SEARCH FOR EFFICIENT INHIBITORS OF MYOTOXIC ACTIVIT BY OPHIDIAN PHOSPHOLIPASE A2-LIKE PROTEINS USING FU STRUCTURAL AND BIOINFORMATICS APPROACHES. SCI REP V. 9 510 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DMS B:201;
A:201;
B:202;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
78.133 C2 H6 O S CS(=O...
AIN B:203;
A:202;
Valid;
Valid;
none;
none;
submit data
180.157 C9 H8 O4 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YV5 1.9 Å EC: 3.1.1.4 CRYSTAL STRUCTURE OF MYOTOXIN II FROM BOTHROPS MOOJENI COMPL SURAMIN BOTHROPS MOOJENI BOTHROPS MOOJENI MYOTOXIN II LYS49-PLA2 SURAMIN TOXIN
Ref.: STRUCTURAL AND FUNCTIONAL EVIDENCE FOR MEMBRANE DOC DISRUPTION SITES ON PHOSPHOLIPASE A2-LIKE PROTEINS BY COMPLEXATION WITH THE INHIBITOR SURAMIN. ACTA CRYSTALLOGR. D BIOL. V. 71 2066 2015 CRYSTALLOGR.
Members (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 5VFM Kd = 150 uM HC4 C9 H8 O3 c1cc(ccc1C....
2 1QLL - TDA C13 H26 O2 CCCCCCCCCC....
3 6MQD - ROA C18 H16 O8 c1cc(c(cc1....
4 4YU7 - DHC C9 H8 O4 c1cc(c(cc1....
5 3MLM - MYR C14 H28 O2 CCCCCCCCCC....
6 3CXI - VIT C29 H50 O2 Cc1c(c2c(c....
7 1XXS - STE C18 H36 O2 CCCCCCCCCC....
8 6PWH - VRD C21 H20 N2 O5 CCc1c(c2c(....
9 3CYL - VIT C29 H50 O2 Cc1c(c2c(c....
10 6MQF - AIN C9 H8 O4 CC(=O)Oc1c....
11 6B81 - OCA C8 H16 O2 CCCCCCCC(=....
12 6DIK - GKP C22 H18 O12 c1c(cc(c(c....
13 6B80 - MYR C14 H28 O2 CCCCCCCCCC....
14 5VFJ Kd = 20 uM DHC C9 H8 O4 c1cc(c(cc1....
15 6B83 - 6NA C6 H12 O2 CCCCCC(=O)....
16 4YV5 Kd = 0.6 uM SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
17 4YZ7 - 9AR C17 H11 N O8 COc1c(ccc2....
18 3QNL - ROA C18 H16 O8 c1cc(c(cc1....
19 1Y4L - SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 5VFM Kd = 150 uM HC4 C9 H8 O3 c1cc(ccc1C....
2 1QLL - TDA C13 H26 O2 CCCCCCCCCC....
3 6MQD - ROA C18 H16 O8 c1cc(c(cc1....
4 4YU7 - DHC C9 H8 O4 c1cc(c(cc1....
5 3MLM - MYR C14 H28 O2 CCCCCCCCCC....
6 3CXI - VIT C29 H50 O2 Cc1c(c2c(c....
7 1XXS - STE C18 H36 O2 CCCCCCCCCC....
8 6PWH - VRD C21 H20 N2 O5 CCc1c(c2c(....
9 3CYL - VIT C29 H50 O2 Cc1c(c2c(c....
10 6MQF - AIN C9 H8 O4 CC(=O)Oc1c....
11 6B81 - OCA C8 H16 O2 CCCCCCCC(=....
12 6DIK - GKP C22 H18 O12 c1c(cc(c(c....
13 6B80 - MYR C14 H28 O2 CCCCCCCCCC....
14 5VFJ Kd = 20 uM DHC C9 H8 O4 c1cc(c(cc1....
15 6B83 - 6NA C6 H12 O2 CCCCCC(=O)....
16 4YV5 Kd = 0.6 uM SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
17 4YZ7 - 9AR C17 H11 N O8 COc1c(ccc2....
18 3QNL - ROA C18 H16 O8 c1cc(c(cc1....
19 1Y4L - SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
20 6CE2 Kd = 0.5 uM SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
21 1S8G - DAO C12 H24 O2 CCCCCCCCCC....
50% Homology Family (86)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 1U4J - MAN C6 H12 O6 C([C@@H]1[....
2 4YU7 - DHC C9 H8 O4 c1cc(c(cc1....
3 3MLM - MYR C14 H28 O2 CCCCCCCCCC....
4 3CXI - VIT C29 H50 O2 Cc1c(c2c(c....
5 1XXS - STE C18 H36 O2 CCCCCCCCCC....
6 6PWH - VRD C21 H20 N2 O5 CCc1c(c2c(....
7 3CYL - VIT C29 H50 O2 Cc1c(c2c(c....
8 6MQF - AIN C9 H8 O4 CC(=O)Oc1c....
9 6B81 - OCA C8 H16 O2 CCCCCCCC(=....
10 6DIK - GKP C22 H18 O12 c1c(cc(c(c....
11 6B80 - MYR C14 H28 O2 CCCCCCCCCC....
12 5VFJ Kd = 20 uM DHC C9 H8 O4 c1cc(c(cc1....
13 6B83 - 6NA C6 H12 O2 CCCCCC(=O)....
14 4YV5 Kd = 0.6 uM SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
15 4YZ7 - 9AR C17 H11 N O8 COc1c(ccc2....
16 3QNL - ROA C18 H16 O8 c1cc(c(cc1....
17 1Y4L - SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
18 1FDK - GLE C16 H32 F3 O6 P CCCCCCCCCC....
19 1MKV - GEL C20 H45 N O8 P2 CCCCCCCCOC....
20 2B96 - ANN C8 H8 O3 COc1ccc(cc....
21 5OW8 ic50 = 6.9 uM AYN C16 H11 F3 N2 O c1ccc2c(c1....
22 4UY1 ic50 = 20 uM TJM C10 H11 N3 O S Cc1cc(c(s1....
23 5OWC ic50 = 0.026 uM AYZ C19 H15 F3 N2 O4 c1cc(cc(c1....
24 5G3M ic50 = 2.2 uM 9JH C14 H13 N O c1ccc(cc1)....
25 2AZY - CHD C24 H40 O5 C[C@H](CCC....
26 1HN4 Kd = 0.15 mM MJI C22 H44 F3 O6 P CCCCCCCCCC....
27 2B01 - TUD C26 H45 N O6 S C[C@H](CCC....
28 1Y6O - MJI C22 H44 F3 O6 P CCCCCCCCCC....
29 2AZZ - TCH C26 H45 N O7 S C[C@H](CCC....
30 2B04 - CHO C26 H43 N O5 C[C@H](CCC....
31 2B00 - GCH C26 H43 N O6 C[C@H](CCC....
32 5P2P - DHG C20 H42 N O6 P CCCCCCCCCC....
33 3O4M - CAQ C6 H6 O2 c1ccc(c(c1....
34 2B03 - TUD C26 H45 N O6 S C[C@H](CCC....
35 1L8S - LPE C26 H57 N O6 P CCCCCCCCCC....
36 1FXF - MJI C22 H44 F3 O6 P CCCCCCCCCC....
37 1FX9 - MJI C22 H44 F3 O6 P CCCCCCCCCC....
38 3QLM Ki = 0.0000158 M PLM C16 H32 O2 CCCCCCCCCC....
39 1POE - GEL C20 H45 N O8 P2 CCCCCCCCOC....
40 1DB4 - 8IN C21 H25 N2 O5 P Cc1c(c2cc(....
41 1KQU - BR4 C25 H33 N O3 c1ccc(cc1)....
42 5G3N ic50 = 0.012 uM X28 C23 H21 N O3 c1ccc(cc1)....
43 1KVO ic50 = 0.013 uM OAP C31 H37 N O3 S c1ccc(cc1)....
44 1J1A ic50 = 0.029 uM BHP C31 H37 N O4 c1ccc(cc1)....
45 6CE2 Kd = 0.5 uM SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
46 2QVD Kd = 0.000000064 M BER C20 H18 N O4 COc1ccc2cc....
47 1ZWP - NIM C13 H12 N2 O5 S CS(=O)(=O)....
48 1OXL - IDA C15 H18 N2 O3 CCCc1cc2cc....
49 1TG4 - PHE LEU ALA TYR LYS n/a n/a
50 1SKG - VAL ALA PHE ARG SER n/a n/a
51 1JQ9 Kd = 3.57 nM PHE LEU SER TYR LYS n/a n/a
52 2ARM Kd = 0.000000064 M OIN C17 H23 N O3 CN1[C@H]2C....
53 1FV0 Ki = 1.18 uM 9AR C17 H11 N O8 COc1c(ccc2....
54 1Q7A Kd = 0.000000064 M OPB C19 H20 N2 O3 CCCC[C@H]1....
55 1TG1 - PHQ LEU VAL ARG TYR n/a n/a
56 1ZYX - LCF C23 H22 Cl N O2 CC1(Cc2c(c....
57 1TJK - PHE LEU SER THR LYS n/a n/a
58 1KPM Ki = 1.59 uM VIT C29 H50 O2 Cc1c(c2c(c....
59 1TP2 - TDA C13 H26 O2 CCCCCCCCCC....
60 1TDV - TYR TRP ALA ALA ALA ALA n/a n/a
61 1TJ9 - VAL ALA ARG SER n/a n/a
62 1JQ8 Ki = 1.01 uM LEU ALA ILE TYR SER n/a n/a
63 1SQZ - PHQ ILE ALA ARG SER n/a n/a
64 1TGM - AIN C9 H8 O4 CC(=O)Oc1c....
65 1ZR8 - AJM C18 H22 N2 O2 C[N@]1c2cc....
66 1TH6 - OIN C17 H23 N O3 CN1[C@H]2C....
67 1Y38 - G3P C3 H9 O6 P C([C@H](CO....
68 3H1X Kd = 0.000000064 M IMN C19 H16 Cl N O4 Cc1c(c2cc(....
69 1SXK - BHA C7 H7 N O3 c1cc(c(cc1....
70 1TK4 - ALA ILE ARG SER n/a n/a
71 1SV3 - ANN C8 H8 O3 COc1ccc(cc....
72 5WZW ic50 = 1.23 uM U8D C22 H27 N2 O5 P CCc1c(c2cc....
73 5WZU ic50 = 0.1 uM 7W3 C21 H17 F3 N2 O5 Cc1c(c2c(n....
74 5WZT ic50 = 0.22 uM 7W6 C20 H17 Br N2 O5 Cc1c(c2c(n....
75 5WZS ic50 = 0.28 uM 7W9 C24 H20 N2 O5 Cc1c(c2c(n....
76 5Y5E - 7W3 C21 H17 F3 N2 O5 Cc1c(c2c(n....
77 5WZV ic50 = 0.21 uM 7W0 C26 H22 N2 O5 Cc1c(c2c(n....
78 6G5J ic50 = 0.2 uM EM8 C20 H17 F3 N2 O4 C[C@H](CC(....
79 2QHD - DAO C12 H24 O2 CCCCCCCCCC....
80 3BJW - SVR C51 H40 N6 O23 S6 Cc1ccc(cc1....
81 1S8G - DAO C12 H24 O2 CCCCCCCCCC....
82 1POB - GEL C20 H45 N O8 P2 CCCCCCCCOC....
83 1TD7 Kd = 43 uM NFL C13 H9 F3 N2 O2 c1cc(cc(c1....
84 1OXR Kd = 0.000000064 M AIN C9 H8 O4 CC(=O)Oc1c....
85 2WQ5 Kd = 180 uM MIY C23 H27 N3 O7 CN(C)c1ccc....
86 1MF4 Ki = 10.2 nM VAL ALA PHE ARG SER n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: AIN; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 AIN 1 1
2 K2P 0.488372 0.740741
3 PHT 0.441176 0.652174
4 M3S 0.413043 0.956522
Similar Ligands (3D)
Ligand no: 1; Ligand: AIN; Similar ligands found: 817
No: Ligand Similarity coefficient
1 QM1 0.9862
2 GV9 0.9721
3 ZZ8 0.9707
4 6XI 0.9590
5 8XQ 0.9561
6 F12 0.9549
7 PRZ 0.9549
8 NTM 0.9514
9 KLW 0.9513
10 2ZQ 0.9510
11 BK9 0.9468
12 IJZ 0.9460
13 HHT 0.9447
14 9KH 0.9425
15 FOT 0.9425
16 HNQ 0.9424
17 NLA 0.9407
18 S3B 0.9403
19 5WY 0.9401
20 AKH 0.9399
21 QPR 0.9398
22 4ME 0.9395
23 HZQ 0.9391
24 GCB 0.9367
25 HA7 0.9366
26 YSO 0.9347
27 7ZE 0.9344
28 V6F 0.9339
29 JKZ 0.9336
30 Z5P 0.9334
31 60Q 0.9333
32 LSA 0.9328
33 42C 0.9328
34 ORO 0.9326
35 M3Q 0.9320
36 DOR 0.9317
37 LT8 0.9314
38 6DP 0.9312
39 495 0.9309
40 UAN 0.9308
41 QMS 0.9307
42 DNC 0.9305
43 GCU 0.9299
44 Q6T 0.9298
45 D1X 0.9298
46 5WX 0.9296
47 8GK 0.9294
48 NCD 0.9294
49 FBG 0.9285
50 IAC 0.9284
51 MT0 0.9282
52 QAS 0.9279
53 GDE 0.9277
54 3IT 0.9276
55 HLZ 0.9275
56 M0Q 0.9269
57 7NI 0.9266
58 7VS 0.9260
59 KFH 0.9253
60 IBM 0.9253
61 YQA 0.9253
62 OTD 0.9250
63 DBJ 0.9244
64 12B 0.9242
65 GOG 0.9240
66 5OF 0.9237
67 7WR 0.9236
68 D07 0.9234
69 512 0.9233
70 HLD 0.9222
71 34D 0.9220
72 NID 0.9220
73 NVU 0.9220
74 GZ8 0.9219
75 2MN 0.9218
76 DHK 0.9216
77 329 0.9213
78 FXH 0.9212
79 XQK 0.9211
80 MQB 0.9210
81 EVA 0.9209
82 CCB 0.9208
83 PXL 0.9202
84 GTC 0.9201
85 IPZ 0.9200
86 GT0 0.9194
87 GUN 0.9191
88 HPT 0.9191
89 M1H 0.9190
90 BGC 0.9187
91 F69 0.9187
92 49O 0.9184
93 XAN 0.9184
94 TSR 0.9181
95 1AL 0.9179
96 URC 0.9175
97 VNL 0.9175
98 1X7 0.9175
99 OA3 0.9175
100 N8P 0.9174
101 TRC 0.9172
102 BDP 0.9172
103 2CL 0.9168
104 GJS 0.9167
105 5NS 0.9167
106 INE 0.9167
107 12M 0.9165
108 LGC 0.9164
109 R9S 0.9163
110 GLY PRO 0.9163
111 61O 0.9161
112 JR2 0.9160
113 4KL 0.9160
114 KIB 0.9160
115 G3F 0.9160
116 9DG 0.9158
117 OMD 0.9156
118 M0W 0.9153
119 2LY 0.9148
120 3C2 0.9148
121 57O 0.9144
122 OXC 0.9142
123 8S0 0.9135
124 PDC 0.9134
125 G1O 0.9129
126 2D3 0.9129
127 AM1 0.9128
128 EV0 0.9127
129 15L 0.9126
130 NTZ 0.9125
131 FLV 0.9124
132 C2U 0.9123
133 GCS 0.9122
134 DNF 0.9121
135 X8D 0.9120
136 UEG 0.9120
137 2AL 0.9119
138 JUG 0.9118
139 APZ 0.9118
140 O2A 0.9118
141 DBH 0.9117
142 4HC 0.9117
143 0LH 0.9116
144 M1E 0.9115
145 9MG 0.9114
146 FE DB1 0.9110
147 GLC 0.9108
148 S7B 0.9106
149 AZ8 0.9104
150 V55 0.9104
151 GM7 0.9103
152 0GZ 0.9102
153 LZ2 0.9100
154 RM1 0.9098
155 1FF 0.9097
156 TQU 0.9094
157 UNC 0.9093
158 KBG 0.9093
159 3C1 0.9091
160 6BL 0.9090
161 PE0 0.9088
162 IGA 0.9087
163 AZA 0.9085
164 FLC 0.9085
165 1U1 0.9084
166 VK3 0.9084
167 7I2 0.9083
168 GAL 0.9083
169 QSH 0.9079
170 I6G 0.9078
171 67X 0.9077
172 KYA 0.9077
173 SXS 0.9077
174 ARP 0.9076
175 J9W 0.9075
176 49N 0.9075
177 141 0.9074
178 0CU 0.9074
179 6AP 0.9072
180 8TX 0.9071
181 5WU 0.9071
182 HJP 0.9070
183 KGK 0.9070
184 TRA 0.9068
185 A13 0.9068
186 CIT 0.9067
187 3MG 0.9066
188 FA6 0.9064
189 AZG 0.9063
190 QAT 0.9063
191 RXA 0.9063
192 HMQ 0.9062
193 ENL 0.9060
194 OHP 0.9059
195 A2F 0.9057
196 0GY 0.9057
197 293 0.9056
198 I3A 0.9056
199 290 0.9056
200 MIG 0.9054
201 692 0.9054
202 DPZ 0.9053
203 PFB 0.9049
204 1XM 0.9049
205 HQ9 0.9049
206 CDV 0.9049
207 P4B 0.9047
208 SYA 0.9046
209 NQ 0.9045
210 52C 0.9044
211 23J 0.9043
212 SHG 0.9042
213 JTH 0.9041
214 ICT 0.9041
215 091 0.9041
216 M5N 0.9038
217 FA3 0.9038
218 209 0.9037
219 SHA 0.9037
220 AQO 0.9036
221 4XH 0.9036
222 7CT 0.9036
223 AJ2 0.9035
224 DX4 0.9035
225 Q88 0.9034
226 4XV 0.9034
227 GOX 0.9034
228 M5K 0.9032
229 BOA 0.9029
230 MHK 0.9028
231 YH7 0.9028
232 C2Y 0.9027
233 MO8 0.9027
234 0W8 0.9025
235 GLG 0.9025
236 9PY 0.9023
237 TEP 0.9023
238 NIG 0.9023
239 H7Y 0.9023
240 KED 0.9023
241 H33 0.9022
242 7HQ 0.9022
243 6GU 0.9021
244 Q24 0.9019
245 EKN 0.9018
246 790 0.9018
247 1Z8 0.9017
248 97T 0.9014
249 NBG 0.9014
250 6VD 0.9014
251 226 0.9013
252 3MA 0.9011
253 EOL 0.9010
254 BMA 0.9009
255 3F0 0.9008
256 MEW 0.9008
257 39A 0.9008
258 ASC 0.9007
259 CFP 0.9006
260 3HA 0.9006
261 9AP 0.9005
262 5RG 0.9005
263 NFQ 0.9001
264 LDR 0.9000
265 SRO 0.8999
266 GTZ 0.8998
267 ICO 0.8997
268 AS3 0.8996
269 K3Q 0.8995
270 SR4 0.8994
271 8VE 0.8993
272 AW5 0.8992
273 CBF 0.8991
274 MMA 0.8991
275 GTR 0.8990
276 2SX 0.8988
277 6R8 0.8986
278 5NE 0.8985
279 FBU 0.8985
280 0P6 0.8984
281 1LN 0.8984
282 FP1 0.8984
283 FGZ 0.8982
284 CKU 0.8982
285 C9E 0.8979
286 VOH 0.8979
287 DIU 0.8979
288 261 0.8977
289 GTL 0.8976
290 PXM 0.8976
291 2LP 0.8976
292 TWO 0.8975
293 HH8 0.8973
294 TSS 0.8970
295 5RN 0.8968
296 XQG 0.8968
297 TVP 0.8967
298 L7T 0.8967
299 DQA 0.8966
300 S76 0.8965
301 KIA 0.8965
302 ADK 0.8963
303 GTQ 0.8962
304 IOS 0.8961
305 8VN 0.8960
306 G5V 0.8959
307 A9O 0.8958
308 2A7 0.8958
309 NDM 0.8955
310 II6 0.8954
311 4XS 0.8952
312 3MB 0.8950
313 54G 0.8950
314 NCV 0.8950
315 LT3 0.8946
316 M4E 0.8945
317 CIP 0.8944
318 M1Q 0.8943
319 7FF 0.8943
320 8WZ 0.8943
321 BCP 0.8943
322 6CS 0.8943
323 K3Y 0.8942
324 REL 0.8942
325 MVL 0.8941
326 OKM 0.8941
327 680 0.8940
328 AEZ 0.8940
329 NTC 0.8940
330 LZM 0.8937
331 CTS 0.8936
332 GLA 0.8936
333 SAL 0.8936
334 KP6 0.8935
335 K5W 0.8935
336 5M0 0.8934
337 92P 0.8933
338 MJ2 0.8932
339 J9Q 0.8932
340 MBG 0.8931
341 N5J 0.8931
342 75K 0.8930
343 1WD 0.8929
344 3RI 0.8927
345 B55 0.8927
346 BE2 0.8926
347 F0J 0.8926
348 NQM 0.8926
349 HXX 0.8926
350 JZ4 0.8925
351 A7W 0.8925
352 ES0 0.8925
353 8IG 0.8924
354 7WV 0.8919
355 06B 0.8919
356 9TZ 0.8919
357 MAN 0.8918
358 XAZ 0.8918
359 1LQ 0.8917
360 HH5 0.8917
361 EA1 0.8916
362 TTY 0.8915
363 J01 0.8914
364 CFA 0.8914
365 LI6 0.8913
366 4MU 0.8912
367 2FG 0.8912
368 UFV 0.8910
369 AX3 0.8909
370 5VJ 0.8909
371 3M0 0.8908
372 MAQ 0.8908
373 DNA 0.8907
374 NOJ 0.8906
375 4HM 0.8905
376 2H5 0.8905
377 M6N 0.8905
378 CWM 0.8905
379 AY4 0.8904
380 JKE 0.8903
381 4AA 0.8902
382 W8G 0.8901
383 BPS 0.8900
384 ZZ3 0.8900
385 JPZ 0.8899
386 5PX 0.8899
387 AH8 0.8899
388 FPK 0.8898
389 MFU 0.8897
390 CKX 0.8897
391 2J9 0.8897
392 5SG 0.8897
393 1LM 0.8897
394 X09 0.8896
395 B2J 0.8896
396 GCW 0.8894
397 42A 0.8894
398 TNF 0.8893
399 PX7 0.8892
400 5MK 0.8891
401 0F9 0.8886
402 BCK 0.8885
403 FB1 0.8885
404 KBB 0.8885
405 37T 0.8884
406 VXX 0.8884
407 ALA LEU 0.8883
408 SOR 0.8883
409 GIO 0.8882
410 GLT 0.8881
411 5IQ 0.8881
412 5HY 0.8880
413 B60 0.8879
414 FRU 0.8878
415 ADA 0.8878
416 TNL 0.8878
417 PYQ 0.8877
418 PQK 0.8876
419 FHN 0.8874
420 N2Z 0.8874
421 DIE 0.8874
422 MT8 0.8873
423 AZ9 0.8873
424 ES1 0.8872
425 4A1 0.8872
426 ZWZ 0.8872
427 H6B 0.8871
428 4YS 0.8870
429 DRL 0.8870
430 149 0.8869
431 5Q0 0.8868
432 9KT 0.8868
433 BSX 0.8868
434 N3W 0.8867
435 AMG 0.8867
436 SWA 0.8866
437 HQY 0.8865
438 GIM 0.8865
439 SFU 0.8864
440 EJZ 0.8864
441 PM6 0.8864
442 5JQ 0.8864
443 EUG 0.8863
444 4M4 0.8863
445 EYK 0.8862
446 HQD 0.8860
447 CLZ 0.8860
448 UFO 0.8859
449 CFF 0.8859
450 5NU 0.8859
451 3CU 0.8858
452 BNT 0.8856
453 NGO 0.8855
454 ZON 0.8855
455 SYR 0.8855
456 FA0 0.8854
457 39U 0.8854
458 PRY 0.8854
459 GIV 0.8852
460 1SQ 0.8852
461 BTY 0.8850
462 KT7 0.8849
463 55D 0.8849
464 T6Z 0.8847
465 6MP 0.8846
466 DBX 0.8845
467 DIN 0.8845
468 67Y 0.8844
469 CN0 0.8843
470 2FY 0.8842
471 ATH 0.8842
472 1XA 0.8842
473 2D0 0.8841
474 B53 0.8841
475 OVM 0.8840
476 3TJ 0.8840
477 3FH 0.8840
478 6LW 0.8838
479 TFU 0.8838
480 FBV 0.8838
481 LYL 0.8837
482 GZQ 0.8837
483 B57 0.8836
484 P84 0.8835
485 878 0.8835
486 G2F 0.8835
487 HPA 0.8834
488 SF9 0.8833
489 9DA 0.8830
490 4TU 0.8830
491 BPU 0.8830
492 1XN 0.8830
493 BP1 0.8829
494 3AL 0.8828
495 7VJ 0.8827
496 CCV 0.8826
497 7M6 0.8826
498 MS9 0.8825
499 3R9 0.8825
500 SX1 0.8825
501 3U4 0.8825
502 1GN 0.8823
503 M2K 0.8823
504 7B3 0.8823
505 TRP 0.8822
506 8WT 0.8821
507 7HP 0.8821
508 9HX 0.8821
509 OIA 0.8819
510 5OB 0.8819
511 ONR 0.8818
512 6W6 0.8817
513 DHB 0.8816
514 505 0.8815
515 2TQ 0.8814
516 GYP 0.8814
517 SLC 0.8814
518 YIO 0.8814
519 CTL 0.8814
520 ES6 0.8813
521 QX4 0.8813
522 2PG 0.8813
523 ADE 0.8812
524 HHA 0.8811
525 7B4 0.8811
526 HTP 0.8810
527 KG1 0.8810
528 BTE 0.8809
529 F81 0.8808
530 FYU 0.8808
531 8CM 0.8808
532 CWS 0.8807
533 JBQ 0.8807
534 MIC 0.8807
535 5CU 0.8801
536 KDO 0.8800
537 7MH 0.8800
538 10L 0.8800
539 FDB 0.8798
540 PZI 0.8798
541 5JL 0.8797
542 0N7 0.8796
543 94B 0.8793
544 JBK 0.8793
545 E7Z 0.8792
546 PA1 0.8791
547 JXW 0.8790
548 SKM 0.8789
549 64C 0.8788
550 0FO 0.8788
551 MRW 0.8787
552 IPT 0.8787
553 LAO 0.8787
554 3SK 0.8786
555 LCN 0.8786
556 XQB 0.8786
557 X6X 0.8785
558 ASO 0.8785
559 EPR 0.8784
560 6ME 0.8784
561 XQI 0.8782
562 SBK 0.8782
563 BZ3 0.8781
564 KUF 0.8780
565 2CG 0.8780
566 44W 0.8780
567 MOK 0.8777
568 BHA 0.8776
569 JZ3 0.8773
570 3WA 0.8773
571 WOO 0.8773
572 OTW 0.8773
573 DQU 0.8772
574 PD2 0.8770
575 96R 0.8770
576 7WA 0.8770
577 CHB 0.8767
578 ES4 0.8766
579 9FQ 0.8766
580 3Z8 0.8766
581 3HB 0.8765
582 6F0 0.8764
583 A9P 0.8764
584 MT5 0.8764
585 N8Y 0.8763
586 87L 0.8762
587 DOB 0.8762
588 FH2 0.8761
589 IV2 0.8761
590 1NP 0.8760
591 MUA 0.8759
592 5RO 0.8759
593 3AB 0.8759
594 M4B 0.8758
595 OBP 0.8758
596 8G0 0.8758
597 23A 0.8758
598 1F1 0.8756
599 XX2 0.8754
600 IFM 0.8754
601 DFB 0.8753
602 MYJ 0.8751
603 3DM 0.8751
604 XHP 0.8750
605 44V 0.8750
606 FDK 0.8749
607 4NC 0.8749
608 P9P 0.8748
609 IBC 0.8748
610 3B4 0.8746
611 B2Y 0.8746
612 INO 0.8746
613 ESI 0.8745
614 OW4 0.8744
615 PEY 0.8743
616 G6D 0.8741
617 XFE 0.8740
618 54X 0.8740
619 ISD 0.8740
620 3Z7 0.8740
621 3DO 0.8737
622 KIF 0.8735
623 BEA 0.8735
624 ALL 0.8734
625 CLU 0.8734
626 NSG 0.8733
627 MVN 0.8733
628 GNL 0.8733
629 IP0 0.8733
630 T6C 0.8732
631 BY5 0.8731
632 ALA PRO 0.8730
633 MA3 0.8730
634 2FQ 0.8729
635 GCV 0.8727
636 ODO 0.8727
637 ZB1 0.8726
638 B62 0.8726
639 VNJ 0.8725
640 3OC 0.8724
641 MCO 0.8722
642 GLF 0.8722
643 2CZ 0.8721
644 EMZ 0.8720
645 QSB 0.8720
646 IHB 0.8718
647 948 0.8718
648 6J9 0.8718
649 X05 0.8717
650 LNR 0.8716
651 K17 0.8715
652 JAA 0.8713
653 QZ8 0.8713
654 FBT 0.8713
655 KJY 0.8712
656 PEZ 0.8712
657 AHR 0.8712
658 CKA 0.8712
659 1WC 0.8710
660 82I 0.8709
661 F52 0.8709
662 NGT 0.8708
663 20J 0.8707
664 582 0.8707
665 G1P 0.8707
666 DCO 0.8706
667 LIP 0.8706
668 DEE 0.8705
669 PHH 0.8705
670 Q7A 0.8704
671 24W 0.8704
672 EXO 0.8704
673 RPQ 0.8703
674 6OT 0.8702
675 N7P 0.8701
676 LFR 0.8698
677 G4D 0.8698
678 LKA 0.8697
679 HMU 0.8696
680 2F6 0.8695
681 ZME 0.8693
682 EGR 0.8693
683 T9G 0.8691
684 IFL 0.8691
685 GYE 0.8690
686 NK 0.8690
687 24B 0.8690
688 93K 0.8688
689 XSP 0.8688
690 2AK 0.8688
691 5FN 0.8688
692 RB2 0.8687
693 JND 0.8687
694 SQP 0.8686
695 GRE 0.8685
696 FUL 0.8684
697 IPB 0.8683
698 SR1 0.8682
699 M1Z 0.8682
700 28N 0.8681
701 2KA 0.8681
702 H5B 0.8680
703 6M1 0.8680
704 MZB 0.8679
705 Q71 0.8679
706 15N 0.8678
707 8WO 0.8678
708 AFR 0.8676
709 4JT 0.8675
710 1QP 0.8674
711 APS 0.8673
712 6M4 0.8673
713 4M0 0.8672
714 AN0 0.8672
715 OXZ 0.8670
716 XH2 0.8670
717 F31 0.8668
718 2ZM 0.8666
719 9TW 0.8666
720 6NI 0.8664
721 SYG 0.8664
722 3R6 0.8664
723 8NX 0.8663
724 NZ3 0.8663
725 GAB 0.8663
726 PRF 0.8663
727 3Y7 0.8660
728 QQQ 0.8659
729 3C7 0.8659
730 NDH 0.8659
731 SVD 0.8656
732 7ME 0.8655
733 NQH 0.8654
734 DTR 0.8654
735 7A3 0.8653
736 4Z4 0.8650
737 40H 0.8646
738 QIC 0.8646
739 KTA 0.8645
740 FUC 0.8644
741 K32 0.8643
742 R8A 0.8641
743 GAF 0.8639
744 5QX 0.8637
745 DHQ 0.8636
746 IFP 0.8633
747 MPK 0.8633
748 2EC 0.8629
749 ZZ2 0.8625
750 NOY 0.8622
751 LDP 0.8621
752 JFJ 0.8620
753 HQJ 0.8616
754 7MX 0.8615
755 DC5 0.8614
756 4SX 0.8614
757 FHB 0.8613
758 SER PRO 0.8613
759 TBP 0.8612
760 18N 0.8610
761 GZL 0.8609
762 B4O 0.8608
763 2HO 0.8608
764 4TE 0.8606
765 X8Z 0.8605
766 KFN 0.8604
767 NAG 0.8603
768 2ZV 0.8603
769 TZE 0.8602
770 8HC 0.8600
771 TBS 0.8600
772 53C 0.8600
773 DMJ 0.8598
774 4CS 0.8598
775 3XX 0.8596
776 ABI 0.8595
777 PFL 0.8594
778 AME 0.8592
779 2XX 0.8590
780 S3C 0.8589
781 XXP 0.8588
782 GXL 0.8584
783 4AN 0.8584
784 ZZT 0.8583
785 TOF 0.8583
786 JAW 0.8581
787 069 0.8580
788 286 0.8579
789 3A9 0.8578
790 4AV 0.8576
791 LRH 0.8576
792 PJW 0.8575
793 X0W 0.8574
794 NNO 0.8573
795 GSY 0.8571
796 XEN 0.8568
797 IPD 0.8565
798 KYD 0.8565
799 5NI 0.8563
800 E35 0.8563
801 4A3 0.8561
802 MXX 0.8560
803 IOP 0.8558
804 HMH 0.8557
805 KTW 0.8557
806 FUF 0.8556
807 FSW 0.8554
808 MFB 0.8549
809 6UA 0.8547
810 9X5 0.8541
811 0FK 0.8540
812 1KH 0.8537
813 XM5 0.8536
814 9R5 0.8533
815 FA1 0.8526
816 JZ1 0.8514
817 0HN 0.8513
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YV5; Ligand: SVR; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 4yv5.bio1) has 118 residues
No: Leader PDB Ligand Sequence Similarity
1 6LM1 OCT 18.8525
2 6LM1 D10 18.8525
Pocket No.: 2; Query (leader) PDB : 4YV5; Ligand: SVR; Similar sites found with APoc: 2
This union binding pocket(no: 2) in the query (biounit: 4yv5.bio1) has 124 residues
No: Leader PDB Ligand Sequence Similarity
1 6LM1 OCT 18.8525
2 6LM1 D10 18.8525
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