Receptor
PDB id Resolution Class Description Source Keywords
6PA9 1.88 Å EC: 3.5.1.1 E. COLI L-ASPARAGINASE II MUTANT (T12V) IN COMPLEX WITH L-AS 7.0 ESCHERICHIA COLI (STRAIN K12) INACTIVE MUTANT HYDROLYSIS OF L-ASPARAGINE HYDROLASE
Ref.: GEOMETRIC CONSIDERATIONS SUPPORT THE DOUBLE-DISPLAC CATALYTIC MECHANISM OF L-ASPARAGINASE. PROTEIN SCI. V. 28 1850 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASN B:401;
A:401;
Valid;
Valid;
none;
none;
submit data
132.118 C4 H8 N2 O3 C([C@...
GOL B:402;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6PAC 1.6 Å EC: 3.5.1.1 E. COLI L-ASPARAGINASE II IN COMPLEX WITH L-ASP AT PH 5.6 ESCHERICHIA COLI (STRAIN K12) INACTIVE MUTANT HYDROLYSIS OF L-ASPARAGINE HYDROLASE
Ref.: GEOMETRIC CONSIDERATIONS SUPPORT THE DOUBLE-DISPLAC CATALYTIC MECHANISM OF L-ASPARAGINASE. PROTEIN SCI. V. 28 1850 2019
Members (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 6V2B - ASN C4 H8 N2 O3 C([C@@H](C....
2 6PA6 - ASN C4 H8 N2 O3 C([C@@H](C....
3 6PAC - ASP C4 H7 N O4 C([C@@H](C....
4 6V29 - ASP C4 H7 N O4 C([C@@H](C....
5 1HO3 - ASP C4 H7 N O4 C([C@@H](C....
6 6V26 - ASP C4 H7 N O4 C([C@@H](C....
7 6PAB - ASP C4 H7 N O4 C([C@@H](C....
8 6PA4 - ASP C4 H7 N O4 C([C@@H](C....
9 6PA8 - ASN C4 H8 N2 O3 C([C@@H](C....
10 6NXB - CIT C6 H8 O7 C(C(=O)O)C....
11 6PAA - ASP C4 H7 N O4 C([C@@H](C....
12 6PA2 - ASP C4 H7 N O4 C([C@@H](C....
13 5MQ5 - ASP C4 H7 N O4 C([C@@H](C....
14 6NX8 - CIT C6 H8 O7 C(C(=O)O)C....
15 6V2A - ASN C4 H8 N2 O3 C([C@@H](C....
16 6PA5 - ASN C4 H8 N2 O3 C([C@@H](C....
17 6NX7 - CIT C6 H8 O7 C(C(=O)O)C....
18 3ECA - ASP C4 H7 N O4 C([C@@H](C....
19 6PA9 - ASN C4 H8 N2 O3 C([C@@H](C....
20 1NNS - ASP C4 H7 N O4 C([C@@H](C....
21 6PA3 - ASN C4 H8 N2 O3 C([C@@H](C....
22 6NX6 - CIT C6 H8 O7 C(C(=O)O)C....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 5K3O - ASP C4 H7 N O4 C([C@@H](C....
2 5K4H - GLU C5 H9 N O4 C(CC(=O)O)....
3 5K45 - GLU C5 H9 N O4 C(CC(=O)O)....
4 5K4G - ASP C4 H7 N O4 C([C@@H](C....
5 2WLT - ASP C4 H7 N O4 C([C@@H](C....
6 2WT4 - ASP C4 H7 N O4 C([C@@H](C....
7 5MQ5 - ASP C4 H7 N O4 C([C@@H](C....
8 6NX8 - CIT C6 H8 O7 C(C(=O)O)C....
9 6V2A - ASN C4 H8 N2 O3 C([C@@H](C....
10 6PA5 - ASN C4 H8 N2 O3 C([C@@H](C....
11 6NX7 - CIT C6 H8 O7 C(C(=O)O)C....
12 3ECA - ASP C4 H7 N O4 C([C@@H](C....
13 6PA9 - ASN C4 H8 N2 O3 C([C@@H](C....
14 1NNS - ASP C4 H7 N O4 C([C@@H](C....
15 6PA3 - ASN C4 H8 N2 O3 C([C@@H](C....
16 6NX6 - CIT C6 H8 O7 C(C(=O)O)C....
50% Homology Family (39)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 1HG0 - SIN C4 H6 O4 C(CC(=O)O)....
2 1HFW - GLU C5 H9 N O4 C(CC(=O)O)....
3 5F52 - ASP C4 H7 N O4 C([C@@H](C....
4 5HW0 - GLU C5 H9 N O4 C(CC(=O)O)....
5 6PAE - ASP C4 H7 N O4 C([C@@H](C....
6 1HG1 - DAS C4 H7 N O4 C([C@H](C(....
7 5K3O - ASP C4 H7 N O4 C([C@@H](C....
8 5K4H - GLU C5 H9 N O4 C(CC(=O)O)....
9 5K45 - GLU C5 H9 N O4 C(CC(=O)O)....
10 5K4G - ASP C4 H7 N O4 C([C@@H](C....
11 2WLT - ASP C4 H7 N O4 C([C@@H](C....
12 2WT4 - ASP C4 H7 N O4 C([C@@H](C....
13 6V2B - ASN C4 H8 N2 O3 C([C@@H](C....
14 6PA6 - ASN C4 H8 N2 O3 C([C@@H](C....
15 6PAC - ASP C4 H7 N O4 C([C@@H](C....
16 6V29 - ASP C4 H7 N O4 C([C@@H](C....
17 1HO3 - ASP C4 H7 N O4 C([C@@H](C....
18 6V26 - ASP C4 H7 N O4 C([C@@H](C....
19 6PAB - ASP C4 H7 N O4 C([C@@H](C....
20 6PA4 - ASP C4 H7 N O4 C([C@@H](C....
21 6PA8 - ASN C4 H8 N2 O3 C([C@@H](C....
22 6NXB - CIT C6 H8 O7 C(C(=O)O)C....
23 6PAA - ASP C4 H7 N O4 C([C@@H](C....
24 6PA2 - ASP C4 H7 N O4 C([C@@H](C....
25 5MQ5 - ASP C4 H7 N O4 C([C@@H](C....
26 6NX8 - CIT C6 H8 O7 C(C(=O)O)C....
27 6V2A - ASN C4 H8 N2 O3 C([C@@H](C....
28 6PA5 - ASN C4 H8 N2 O3 C([C@@H](C....
29 6NX7 - CIT C6 H8 O7 C(C(=O)O)C....
30 3ECA - ASP C4 H7 N O4 C([C@@H](C....
31 6PA9 - ASN C4 H8 N2 O3 C([C@@H](C....
32 1NNS - ASP C4 H7 N O4 C([C@@H](C....
33 6PA3 - ASN C4 H8 N2 O3 C([C@@H](C....
34 6NX6 - CIT C6 H8 O7 C(C(=O)O)C....
35 6WYW - ASP C4 H7 N O4 C([C@@H](C....
36 6WYY - GLU C5 H9 N O4 C(CC(=O)O)....
37 6WYX - ASP C4 H7 N O4 C([C@@H](C....
38 6WYZ - DGL C5 H9 N O4 C(CC(=O)O)....
39 2JK0 - ASP C4 H7 N O4 C([C@@H](C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ASN; Similar ligands found: 23
No: Ligand ECFP6 Tc MDL keys Tc
1 ASN 1 1
2 ASP 0.636364 0.793103
3 DAS 0.636364 0.793103
4 DBB 0.545455 0.6
5 SER 0.545455 0.625
6 2RA 0.545455 0.65625
7 DSN 0.545455 0.625
8 ABA 0.545455 0.6
9 CYS 0.521739 0.612903
10 DCY 0.521739 0.612903
11 SD4 0.5 0.756757
12 DGN 0.481481 0.833333
13 GLN 0.481481 0.833333
14 HSE 0.48 0.666667
15 DAB 0.48 0.636364
16 API 0.461538 0.65625
17 CSO 0.461538 0.611111
18 AS2 0.461538 0.785714
19 HGY 0.428571 0.6
20 GGL 0.428571 0.677419
21 GLU 0.428571 0.677419
22 DGL 0.428571 0.677419
23 ONL 0.4 0.617647
Similar Ligands (3D)
Ligand no: 1; Ligand: ASN; Similar ligands found: 1137
No: Ligand Similarity coefficient
1 LMR 1.0000
2 MLT 1.0000
3 CIZ 1.0000
4 HRZ 1.0000
5 LEU 0.9978
6 CRN 0.9973
7 OAA 0.9972
8 ITN 0.9966
9 CMS 0.9918
10 IOM 0.9909
11 JYD 0.9889
12 COI 0.9859
13 UGC 0.9786
14 98J 0.9724
15 40E 0.9723
16 TAR 0.9720
17 TEO 0.9713
18 SIN 0.9703
19 HL5 0.9685
20 DYA 0.9675
21 SHF 0.9649
22 4MV 0.9645
23 AHB 0.9635
24 AL0 0.9623
25 SRT 0.9619
26 GUA 0.9614
27 FUM 0.9612
28 2RH 0.9606
29 MAE 0.9605
30 MLE 0.9602
31 2AS 0.9601
32 NVA 0.9601
33 NMG 0.9596
34 LNO 0.9593
35 3SL 0.9588
36 6PC 0.9584
37 S2G 0.9576
38 AKG 0.9567
39 GZ3 0.9543
40 2IT 0.9541
41 YCP 0.9537
42 PPR 0.9537
43 9YL 0.9527
44 SS1 0.9527
45 9X7 0.9524
46 TLA 0.9524
47 ILE 0.9522
48 2CO 0.9521
49 OEM 0.9521
50 DCL 0.9519
51 BAM 0.9515
52 HDA 0.9509
53 PEP 0.9508
54 SPV 0.9504
55 QSC 0.9504
56 NIO 0.9504
57 7N0 0.9502
58 9ON 0.9497
59 BEZ 0.9497
60 BEN 0.9495
61 AC5 0.9493
62 SKG 0.9491
63 VAL 0.9491
64 PZA 0.9488
65 ORN 0.9485
66 THE 0.9481
67 PCA 0.9479
68 9X6 0.9478
69 5AC 0.9477
70 NLE 0.9473
71 SS2 0.9471
72 PEQ 0.9470
73 0V5 0.9470
74 HIO 0.9470
75 HCS 0.9469
76 QFH 0.9469
77 NCA 0.9461
78 NXA 0.9460
79 KMH 0.9454
80 WTZ 0.9453
81 6JN 0.9453
82 CP 0.9452
83 S0H 0.9452
84 NBZ 0.9452
85 PZI 0.9451
86 M58 0.9446
87 O7U 0.9438
88 UNU 0.9438
89 PRO 0.9437
90 UYA 0.9422
91 PBC 0.9420
92 VGL 0.9418
93 BNS 0.9418
94 GAG 0.9417
95 T2C 0.9413
96 HZP 0.9412
97 THR 0.9409
98 H95 0.9408
99 URP 0.9407
100 APY 0.9405
101 HX2 0.9404
102 VAH 0.9402
103 DXX 0.9399
104 8EW 0.9399
105 7VD 0.9399
106 69O 0.9390
107 AKB 0.9386
108 MET 0.9383
109 23B 0.9380
110 PLU 0.9378
111 M6W 0.9376
112 PG3 0.9375
113 IXW 0.9372
114 MRZ 0.9368
115 NTN 0.9367
116 273 0.9366
117 3HG 0.9362
118 1DQ 0.9360
119 2PC 0.9358
120 OKG 0.9358
121 BHO 0.9358
122 TZE 0.9357
123 X1S 0.9357
124 RSO 0.9356
125 192 0.9352
126 KIV 0.9350
127 ISZ 0.9346
128 TFB 0.9345
129 URQ 0.9343
130 JZ7 0.9342
131 2PG 0.9341
132 IHG 0.9329
133 4CS 0.9325
134 FPI 0.9324
135 GJZ 0.9324
136 6M4 0.9322
137 PRS 0.9317
138 PMB 0.9314
139 60P 0.9313
140 PAE 0.9311
141 AC0 0.9311
142 PYC 0.9310
143 IZC 0.9307
144 CSS 0.9306
145 LDU 0.9300
146 OGA 0.9300
147 ACH 0.9299
148 HY3 0.9299
149 CXF 0.9298
150 R67 0.9297
151 5XB 0.9295
152 RBL 0.9292
153 TP5 0.9292
154 7WG 0.9292
155 FOC 0.9291
156 OEG 0.9290
157 EHM 0.9288
158 9TY 0.9288
159 FPY 0.9287
160 TZC 0.9286
161 TB6 0.9284
162 B24 0.9283
163 PGA 0.9282
164 51F 0.9281
165 URF 0.9280
166 DPR 0.9278
167 1AB 0.9278
168 NBE 0.9278
169 3AB 0.9276
170 FLA 0.9274
171 MXN 0.9274
172 SME 0.9271
173 XBT 0.9270
174 SYN 0.9270
175 ALO 0.9268
176 ICF 0.9267
177 OK7 0.9264
178 HBX 0.9262
179 BE2 0.9261
180 1SP 0.9259
181 3OC 0.9259
182 TZL 0.9258
183 ZBT 0.9258
184 FOA 0.9258
185 N8P 0.9257
186 PHB 0.9257
187 MRY 0.9256
188 HYP 0.9254
189 PAC 0.9253
190 SAL 0.9253
191 PYJ 0.9248
192 GBD 0.9247
193 QY9 0.9244
194 NPO 0.9244
195 R2B 0.9243
196 MEV 0.9242
197 0VT 0.9239
198 SC2 0.9239
199 ABU 0.9239
200 FBJ 0.9237
201 ABN 0.9235
202 HIS 0.9233
203 PYF 0.9233
204 MPD 0.9232
205 GAB 0.9232
206 PAF 0.9230
207 5FX 0.9229
208 1Y6 0.9229
209 MAK 0.9229
210 PEL 0.9228
211 NMJ 0.9228
212 PAB 0.9227
213 M4T 0.9227
214 PBE 0.9226
215 2HG 0.9225
216 LEA 0.9224
217 49F 0.9223
218 VNJ 0.9223
219 MSE 0.9222
220 URA 0.9222
221 2AL 0.9219
222 3AL 0.9219
223 DPF 0.9219
224 AMC 0.9217
225 HY1 0.9217
226 KMT 0.9216
227 282 0.9216
228 FEH 0.9215
229 MUC 0.9215
230 F9P 0.9214
231 CFI 0.9213
232 SEP 0.9212
233 WBU 0.9212
234 FQI 0.9212
235 OSE 0.9207
236 AC6 0.9207
237 DYT 0.9206
238 HHI 0.9204
239 IP0 0.9204
240 HBA 0.9203
241 5HY 0.9201
242 3U4 0.9201
243 XSP 0.9200
244 7A8 0.9199
245 2FT 0.9198
246 4XR 0.9198
247 ES6 0.9198
248 PY7 0.9194
249 LER 0.9193
250 8EZ 0.9193
251 HTX 0.9190
252 TIH 0.9189
253 3NT 0.9189
254 SHO 0.9188
255 1DV 0.9188
256 DHB 0.9188
257 RIB 0.9187
258 PEA 0.9186
259 MD0 0.9185
260 GG6 0.9184
261 DAL DAL 0.9183
262 OXQ 0.9183
263 2MH 0.9182
264 IFM 0.9182
265 FBM 0.9180
266 FB2 0.9180
267 TPA 0.9180
268 7BC 0.9177
269 0OC 0.9177
270 271 0.9177
271 HYA 0.9176
272 AG2 0.9176
273 PHU 0.9176
274 HBD 0.9176
275 HSM 0.9174
276 P72 0.9174
277 SGL 0.9173
278 VKC 0.9173
279 TMH 0.9172
280 MED 0.9172
281 BML 0.9169
282 1MR 0.9167
283 IT2 0.9164
284 14J 0.9164
285 DQY 0.9163
286 OVV 0.9163
287 4CH 0.9163
288 SSN 0.9162
289 EDG 0.9161
290 URO 0.9161
291 3HB 0.9161
292 XLS 0.9156
293 K6H 0.9153
294 MYJ 0.9152
295 KPL 0.9150
296 23W 0.9149
297 RIP 0.9147
298 P9P 0.9146
299 H3M 0.9145
300 I2M 0.9144
301 SMB 0.9141
302 XYL 0.9140
303 QDK 0.9140
304 RB0 0.9140
305 RB5 0.9140
306 C21 0.9140
307 FAN 0.9140
308 3S5 0.9139
309 DMV 0.9139
310 FBV 0.9138
311 HPA 0.9138
312 IDM 0.9137
313 XUL 0.9136
314 NIZ 0.9136
315 RNS 0.9135
316 GRO 0.9135
317 9CL 0.9135
318 PEZ 0.9134
319 SMV 0.9134
320 HSO 0.9134
321 3PP 0.9133
322 MWM 0.9130
323 XM0 0.9129
324 I1E 0.9127
325 JKE 0.9126
326 4MA 0.9126
327 6NA 0.9124
328 RMN 0.9123
329 3SK 0.9122
330 0MK 0.9122
331 JBN 0.9121
332 173 0.9121
333 PCT 0.9120
334 4VP 0.9117
335 3PY 0.9117
336 SJ5 0.9116
337 DFB 0.9116
338 IQ0 0.9115
339 MYQ 0.9113
340 ICN 0.9113
341 FPK 0.9113
342 ROR 0.9112
343 FP1 0.9112
344 MCT 0.9112
345 GLL 0.9112
346 PYD 0.9111
347 8OZ 0.9111
348 OXZ 0.9111
349 3LR 0.9110
350 9RW 0.9110
351 MNN 0.9110
352 1WD 0.9110
353 4NC 0.9109
354 13P 0.9109
355 HUI 0.9108
356 DOR 0.9106
357 BP9 0.9106
358 CAQ 0.9106
359 UY7 0.9105
360 XYP 0.9105
361 MEQ 0.9104
362 IMR 0.9102
363 URS 0.9100
364 Z82 0.9099
365 39J 0.9098
366 64K 0.9098
367 3BZ 0.9098
368 6CS 0.9097
369 2TQ 0.9097
370 ASC 0.9096
371 DE2 0.9095
372 DAV 0.9095
373 AZF 0.9095
374 G3P 0.9095
375 R1X 0.9094
376 PAH 0.9091
377 FW5 0.9090
378 1P3 0.9090
379 2DR 0.9089
380 SW7 0.9089
381 CHB 0.9089
382 53C 0.9088
383 PBZ 0.9087
384 SHA 0.9085
385 DFU 0.9085
386 AHR 0.9084
387 AUD 0.9083
388 CDV 0.9081
389 SMN 0.9080
390 3ZQ 0.9079
391 FB1 0.9079
392 SAT 0.9077
393 4JU 0.9076
394 PPV 0.9076
395 CEE 0.9075
396 MLI 0.9075
397 26D 0.9075
398 NVI 0.9074
399 SYM 0.9072
400 KOJ 0.9072
401 3PG 0.9071
402 BE7 0.9071
403 RHU 0.9071
404 RUU 0.9070
405 BDR 0.9070
406 PRI 0.9070
407 1MC 0.9070
408 51R 0.9070
409 K34 0.9069
410 4ZE 0.9067
411 OPE 0.9067
412 1DJ 0.9067
413 8GC 0.9067
414 TDR 0.9066
415 2AC 0.9065
416 JLZ 0.9064
417 1DU 0.9063
418 CRS 0.9063
419 03W 0.9062
420 DGY 0.9062
421 HGQ 0.9062
422 ODV 0.9060
423 93K 0.9059
424 OHG 0.9058
425 285 0.9057
426 ADE 0.9057
427 XYS 0.9056
428 54D 0.9054
429 16D 0.9053
430 MZ0 0.9053
431 TSU 0.9053
432 FCR 0.9052
433 PSJ 0.9051
434 R8A 0.9051
435 LCN 0.9051
436 1SA 0.9050
437 CHT 0.9050
438 MLA 0.9050
439 C2N 0.9050
440 258 0.9049
441 CEJ 0.9048
442 129 0.9047
443 IT9 0.9047
444 LTL 0.9046
445 261 0.9046
446 ARA 0.9046
447 3V4 0.9045
448 ZZT 0.9045
449 BZX 0.9045
450 ORO 0.9044
451 NOJ 0.9044
452 TAG 0.9043
453 GIF 0.9042
454 KYD 0.9042
455 HX3 0.9041
456 YHO 0.9041
457 HDH 0.9041
458 LXC 0.9039
459 5JC 0.9038
460 DGJ 0.9038
461 JZ3 0.9038
462 IF7 0.9037
463 PG0 0.9037
464 GLY ALA 0.9036
465 TM7 0.9035
466 3HL 0.9035
467 IDH 0.9035
468 2HO 0.9035
469 2MP 0.9034
470 TNE 0.9034
471 32O 0.9033
472 XYD 0.9033
473 34A 0.9033
474 HPY 0.9033
475 A1U 0.9032
476 ICP 0.9032
477 ACA 0.9032
478 EKZ 0.9032
479 R9M 0.9031
480 275 0.9031
481 7WV 0.9030
482 ABE 0.9030
483 QOS 0.9029
484 IFL 0.9029
485 I38 0.9028
486 GLY GLY 0.9028
487 XBZ 0.9026
488 I4B 0.9026
489 1GP 0.9026
490 HIU 0.9025
491 SOL 0.9025
492 2YU 0.9025
493 X0V 0.9025
494 FJO 0.9024
495 265 0.9024
496 FBW 0.9024
497 FUD 0.9022
498 Q88 0.9022
499 1AC 0.9021
500 4HO 0.9020
501 4CL 0.9020
502 DBH 0.9020
503 PYG 0.9020
504 SNE 0.9019
505 4FH 0.9019
506 9J3 0.9018
507 2IM 0.9018
508 DTL 0.9016
509 C5J 0.9016
510 BEW 0.9015
511 RSF 0.9014
512 ZGL 0.9014
513 ARB 0.9014
514 IHB 0.9014
515 3HR 0.9013
516 HT4 0.9013
517 SPA 0.9013
518 NYL 0.9013
519 1PT 0.9013
520 7HP 0.9012
521 DS0 0.9008
522 AFR 0.9008
523 N7P 0.9008
524 INO 0.9008
525 6HQ 0.9006
526 MZG 0.9005
527 4JJ 0.9005
528 F05 0.9005
529 A8C 0.9004
530 L3Q 0.9004
531 SEJ 0.9004
532 2KT 0.9002
533 2LP 0.9002
534 40O 0.9002
535 G2H 0.9001
536 XX2 0.9001
537 24B 0.9000
538 4SV 0.9000
539 JZ2 0.9000
540 BAE 0.9000
541 43M 0.8999
542 1LN 0.8998
543 OTR 0.8998
544 152 0.8997
545 DHS 0.8995
546 5MH 0.8995
547 PTO 0.8992
548 280 0.8992
549 IVA 0.8991
550 TIU 0.8991
551 A20 0.8990
552 COM 0.8989
553 34V 0.8986
554 OAF 0.8986
555 IPH 0.8986
556 XCZ 0.8985
557 JZ5 0.8983
558 GLC 0.8983
559 3HA 0.8982
560 GPJ 0.8980
561 GPF 0.8980
562 FBA 0.8980
563 RNT 0.8979
564 284 0.8979
565 CXL 0.8979
566 AGK 0.8976
567 DHI 0.8975
568 27Y 0.8974
569 KVP 0.8974
570 5UC 0.8973
571 TAU 0.8971
572 FUB 0.8971
573 NFQ 0.8970
574 KDF 0.8970
575 DMG 0.8970
576 J1Z 0.8969
577 TH0 0.8968
578 H8N 0.8968
579 9TW 0.8968
580 JZ9 0.8966
581 TH7 0.8966
582 FA1 0.8965
583 SKJ 0.8965
584 449 0.8965
585 4JL 0.8965
586 HVQ 0.8965
587 4P5 0.8965
588 LLQ 0.8964
589 NK 0.8962
590 FSG 0.8961
591 FCN 0.8960
592 SAN 0.8960
593 PRY 0.8959
594 0R0 0.8959
595 2MI 0.8957
596 K5W 0.8957
597 717 0.8957
598 DUC 0.8956
599 1SH 0.8956
600 BVC 0.8955
601 AT3 0.8954
602 9EW 0.8953
603 A09 0.8952
604 FYU 0.8951
605 G3H 0.8951
606 MNM 0.8950
607 IPU 0.8949
608 CCE 0.8948
609 G2F 0.8948
610 A3B 0.8947
611 DMJ 0.8947
612 POP 0.8946
613 HMH 0.8946
614 3SS 0.8944
615 MWJ 0.8943
616 GYE 0.8942
617 CNL 0.8941
618 ETM 0.8941
619 5HN 0.8941
620 3XX 0.8941
621 4M0 0.8941
622 Y8I 0.8940
623 286 0.8940
624 ECE 0.8940
625 BSX 0.8938
626 BTE 0.8938
627 D1X 0.8937
628 ABV 0.8936
629 23A 0.8936
630 C2A 0.8936
631 EFS 0.8934
632 KG7 0.8934
633 2XX 0.8933
634 R9S 0.8933
635 DTU 0.8930
636 T9G 0.8930
637 XRG 0.8929
638 SVJ 0.8929
639 FUC 0.8928
640 069 0.8927
641 MAH 0.8924
642 IP8 0.8924
643 JFJ 0.8923
644 2D0 0.8922
645 F81 0.8922
646 Z6J 0.8921
647 PIS 0.8921
648 JZ1 0.8921
649 AX7 0.8920
650 FA0 0.8920
651 HMU 0.8919
652 NSP 0.8919
653 MLM 0.8919
654 BR9 0.8918
655 BZ3 0.8918
656 6LW 0.8917
657 270 0.8917
658 6UA 0.8917
659 278 0.8915
660 AAE 0.8914
661 LFC 0.8914
662 DEN 0.8914
663 C2B 0.8914
664 FUL 0.8912
665 3FH 0.8911
666 7MH 0.8911
667 IND 0.8910
668 3YP 0.8910
669 2K4 0.8909
670 5NU 0.8909
671 JZ4 0.8908
672 WCE 0.8908
673 G4D 0.8907
674 LZ1 0.8906
675 4LR 0.8905
676 FBS 0.8905
677 MTL 0.8904
678 SOE 0.8902
679 AOS 0.8901
680 GP9 0.8901
681 BGC 0.8901
682 1LQ 0.8901
683 NLP 0.8900
684 9YT 0.8900
685 4J8 0.8897
686 XPO 0.8896
687 4FA 0.8896
688 52C 0.8895
689 5DI 0.8894
690 ES0 0.8893
691 CWM 0.8893
692 BRT 0.8891
693 4NG 0.8891
694 SYG 0.8891
695 F60 0.8890
696 LSA 0.8889
697 ICC 0.8888
698 VPR 0.8886
699 NK2 0.8886
700 K6V 0.8885
701 4PW 0.8885
702 8K2 0.8884
703 PIM 0.8884
704 SVD 0.8883
705 IUR 0.8882
706 3F0 0.8881
707 826 0.8881
708 4SD 0.8880
709 WOT 0.8880
710 2PN 0.8879
711 PKU 0.8879
712 PLQ 0.8878
713 DOB 0.8878
714 G8M 0.8877
715 0R1 0.8877
716 14O 0.8877
717 8H8 0.8877
718 4DX 0.8877
719 LRH 0.8876
720 LYS 0.8875
721 DLY 0.8875
722 2CK 0.8875
723 P2D 0.8873
724 BVG 0.8873
725 GTQ 0.8873
726 FAC 0.8872
727 4JT 0.8871
728 BZI 0.8870
729 5H1 0.8870
730 N4B 0.8870
731 PSE 0.8868
732 RP7 0.8866
733 TYL 0.8866
734 4RW 0.8865
735 PGH 0.8865
736 5CU 0.8864
737 P7I 0.8863
738 FCA 0.8862
739 ISD 0.8861
740 6M9 0.8861
741 SVN 0.8861
742 FPN 0.8860
743 VX 0.8859
744 3M0 0.8858
745 4JM 0.8858
746 QMP 0.8858
747 HAI 0.8857
748 911 0.8856
749 0RW 0.8856
750 JBE 0.8856
751 MPI 0.8855
752 GVH 0.8854
753 10L 0.8854
754 34D 0.8854
755 POA 0.8854
756 FUF 0.8854
757 8X3 0.8853
758 9TZ 0.8853
759 BUB 0.8853
760 LNR 0.8853
761 OXC 0.8850
762 XAN 0.8850
763 NOY 0.8849
764 149 0.8849
765 P92 0.8849
766 BZF 0.8848
767 4JP 0.8848
768 NNO 0.8847
769 2HE 0.8845
770 TLD 0.8845
771 LYL 0.8845
772 JAB 0.8844
773 OHP 0.8843
774 67N 0.8841
775 6AI 0.8840
776 HQE 0.8840
777 ALA ALA 0.8839
778 DHK 0.8839
779 RCO 0.8838
780 9DG 0.8838
781 5MI 0.8837
782 FBT 0.8836
783 3RK 0.8835
784 JAE 0.8835
785 RM4 0.8835
786 S76 0.8833
787 LG4 0.8833
788 AAS 0.8833
789 RAT 0.8832
790 FHB 0.8831
791 2FY 0.8830
792 2A7 0.8829
793 BHA 0.8829
794 4SX 0.8827
795 5MB 0.8826
796 3BU 0.8825
797 4JO 0.8824
798 MZW 0.8824
799 HV2 0.8823
800 DA1 0.8822
801 0TR 0.8821
802 YRL 0.8821
803 5RG 0.8818
804 PCR 0.8817
805 FRU 0.8817
806 IFP 0.8817
807 BTL 0.8816
808 LPK 0.8815
809 AEF 0.8814
810 T6C 0.8814
811 9HX 0.8813
812 174 0.8813
813 3HM 0.8813
814 5M0 0.8813
815 CYH 0.8813
816 2EZ 0.8812
817 7MU 0.8812
818 GAL 0.8811
819 PRA 0.8811
820 4A3 0.8809
821 PXY 0.8808
822 AMS 0.8806
823 AW5 0.8806
824 264 0.8806
825 6F0 0.8805
826 92K 0.8804
827 BDF 0.8803
828 PMF 0.8803
829 GUN 0.8803
830 0CT 0.8802
831 SWD 0.8802
832 PPF 0.8799
833 1XX 0.8799
834 MR1 0.8798
835 N6C 0.8797
836 LYN 0.8795
837 SOR 0.8794
838 HPS 0.8793
839 11S 0.8792
840 IPB 0.8791
841 PRZ 0.8791
842 BNF 0.8791
843 C5A 0.8790
844 JIF 0.8789
845 3CH 0.8789
846 FCB 0.8787
847 SDD 0.8787
848 4HM 0.8785
849 OXE 0.8784
850 RUJ 0.8784
851 M1A 0.8784
852 EOU 0.8784
853 9DA 0.8783
854 L60 0.8783
855 6MP 0.8782
856 54G 0.8781
857 J9Q 0.8780
858 N2Z 0.8780
859 V55 0.8778
860 LG3 0.8778
861 RM1 0.8777
862 CYT 0.8776
863 ODO 0.8776
864 A2Q 0.8775
865 HBU 0.8773
866 NM3 0.8773
867 NM2 0.8773
868 MAN 0.8773
869 NEQ 0.8773
870 95Z 0.8773
871 SKM 0.8772
872 7WA 0.8772
873 TFS 0.8771
874 LDP 0.8771
875 GBN 0.8771
876 BHH 0.8770
877 25R 0.8769
878 5MK 0.8769
879 MB3 0.8769
880 4ZC 0.8768
881 LG5 0.8767
882 97T 0.8767
883 3HP 0.8766
884 2A9 0.8765
885 HH5 0.8764
886 BVF 0.8763
887 4HS 0.8762
888 1P8 0.8762
889 41K 0.8761
890 24W 0.8761
891 PUT 0.8761
892 YTB 0.8761
893 FK8 0.8760
894 P3K 0.8758
895 1AN 0.8757
896 BP1 0.8757
897 2EH 0.8755
898 23J 0.8755
899 HC4 0.8755
900 A13 0.8754
901 ES9 0.8753
902 DCD 0.8753
903 SYC 0.8750
904 ET2 0.8750
905 CAM 0.8749
906 DTT 0.8749
907 FP2 0.8749
908 APG 0.8749
909 H76 0.8748
910 EV0 0.8747
911 3QM 0.8747
912 L89 0.8747
913 IPM 0.8746
914 FOT 0.8744
915 1WG 0.8743
916 JBK 0.8742
917 GLO 0.8740
918 948 0.8739
919 H4N 0.8739
920 FK1 0.8739
921 92Z 0.8738
922 SHI 0.8738
923 2FG 0.8738
924 ASO 0.8738
925 PM6 0.8732
926 2AF 0.8730
927 ES4 0.8730
928 S2P 0.8730
929 GLA 0.8730
930 ZZ3 0.8729
931 B0D 0.8728
932 AS3 0.8728
933 GDE 0.8728
934 GOL 0.8728
935 IPZ 0.8728
936 8LG 0.8727
937 42J 0.8727
938 ZXD 0.8727
939 HHH 0.8727
940 2CQ 0.8726
941 5XC 0.8725
942 PAV 0.8724
943 J9T 0.8724
944 TBP 0.8724
945 DE5 0.8724
946 7CZ 0.8723
947 HEW 0.8722
948 25W 0.8722
949 SF6 0.8721
950 150 0.8721
951 GXE 0.8721
952 LGC 0.8721
953 NCM 0.8721
954 GAF 0.8720
955 OMD 0.8720
956 2CH 0.8719
957 B3U 0.8718
958 QUZ 0.8718
959 HHA 0.8718
960 JZ0 0.8716
961 8GF 0.8716
962 DBX 0.8715
963 KBG 0.8715
964 93B 0.8715
965 M45 0.8714
966 3Q7 0.8713
967 SX1 0.8712
968 4HA 0.8710
969 F0J 0.8710
970 1XN 0.8709
971 JBH 0.8709
972 FA3 0.8709
973 KDG 0.8706
974 RAM 0.8705
975 76X 0.8704
976 3GR 0.8703
977 NPY 0.8703
978 2H5 0.8701
979 4P0 0.8696
980 XXR 0.8696
981 PHE 0.8696
982 HYN 0.8694
983 MBD 0.8694
984 42C 0.8694
985 3FA 0.8694
986 BXO 0.8693
987 I3A 0.8693
988 5OB 0.8693
989 GRE 0.8693
990 5WV 0.8689
991 1SQ 0.8687
992 B3R 0.8685
993 PE9 0.8681
994 JPZ 0.8679
995 4JN 0.8679
996 KTA 0.8678
997 5SG 0.8677
998 CLW 0.8676
999 93Q 0.8675
1000 ES7 0.8675
1001 YIO 0.8675
1002 TPO 0.8674
1003 M3T 0.8672
1004 PA1 0.8672
1005 KKN 0.8670
1006 ISN 0.8670
1007 5IQ 0.8668
1008 4M4 0.8666
1009 EUG 0.8666
1010 B85 0.8666
1011 ARW 0.8666
1012 PZM 0.8666
1013 EDR 0.8665
1014 36R 0.8665
1015 G6D 0.8665
1016 3Z7 0.8665
1017 9SB 0.8664
1018 ES2 0.8663
1019 Q6T 0.8663
1020 ETX 0.8662
1021 8NY 0.8662
1022 1LM 0.8662
1023 2AP 0.8660
1024 6X8 0.8659
1025 3ID 0.8657
1026 N5J 0.8657
1027 XAP 0.8655
1028 45C 0.8655
1029 3MV 0.8655
1030 6M1 0.8655
1031 4H2 0.8654
1032 RBJ 0.8654
1033 BR8 0.8652
1034 7W4 0.8648
1035 1NP 0.8647
1036 HCI 0.8646
1037 2F6 0.8646
1038 AMH 0.8645
1039 AZA 0.8644
1040 BCU 0.8644
1041 GLY PRO 0.8642
1042 3MC 0.8642
1043 5Q0 0.8642
1044 3AP 0.8642
1045 HVK 0.8642
1046 938 0.8640
1047 MBN 0.8640
1048 2ZV 0.8640
1049 PPY 0.8639
1050 24T 0.8638
1051 4AP 0.8637
1052 HTS 0.8636
1053 GCO 0.8636
1054 GZL 0.8636
1055 KVV 0.8636
1056 CIG 0.8635
1057 GLF 0.8635
1058 HQY 0.8635
1059 NTM 0.8634
1060 25T 0.8633
1061 SIF 0.8633
1062 4YS 0.8633
1063 GCS 0.8633
1064 1DH 0.8632
1065 B40 0.8632
1066 K2T 0.8630
1067 9PO 0.8630
1068 269 0.8628
1069 5VM 0.8628
1070 MDN 0.8627
1071 SWA 0.8626
1072 ES1 0.8625
1073 7HQ 0.8625
1074 MWP 0.8622
1075 3DY 0.8620
1076 13X 0.8619
1077 G5V 0.8619
1078 FBB 0.8619
1079 FLM 0.8618
1080 IOL 0.8618
1081 GOO 0.8616
1082 GXV 0.8616
1083 03V 0.8616
1084 TZZ 0.8616
1085 3DM 0.8616
1086 1DW 0.8613
1087 CFP 0.8612
1088 COU 0.8611
1089 TC7 0.8610
1090 GXL 0.8610
1091 XQ0 0.8607
1092 TMZ 0.8607
1093 ALL 0.8605
1094 8CL 0.8604
1095 AH8 0.8598
1096 HHQ 0.8596
1097 X6X 0.8596
1098 E4P 0.8594
1099 AX2 0.8594
1100 BMA 0.8594
1101 MZT 0.8593
1102 CTS 0.8591
1103 A2F 0.8591
1104 2C9 0.8590
1105 JF6 0.8588
1106 ES5 0.8585
1107 DMD 0.8584
1108 4XV 0.8584
1109 FFP 0.8583
1110 VGD 0.8580
1111 45L 0.8580
1112 1M2 0.8577
1113 H42 0.8576
1114 PHT 0.8575
1115 B53 0.8574
1116 290 0.8573
1117 R8V 0.8573
1118 MFB 0.8572
1119 6AP 0.8571
1120 2AQ 0.8564
1121 4FS 0.8560
1122 4Z4 0.8559
1123 3AY 0.8555
1124 YAN 0.8552
1125 AEG 0.8552
1126 GMN 0.8550
1127 GIO 0.8549
1128 VOH 0.8548
1129 K7M 0.8546
1130 F31 0.8543
1131 NDH 0.8542
1132 4XH 0.8541
1133 8SZ 0.8540
1134 HFA 0.8532
1135 AOA 0.8527
1136 AHN 0.8520
1137 TTL 0.8513
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 6pac.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 5DNC ASN 27.8443
2 5DNC ASN 27.8443
Pocket No.: 2; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6pac.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 6pac.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 5DNC ASN 27.8443
2 5DNC ASN 27.8443
Pocket No.: 4; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 6pac.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: 6
This union binding pocket(no: 5) in the query (biounit: 6pac.bio2) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 5DNC ASN 27.8443
2 5DNC ASN 27.8443
3 5DNC ASN 27.8443
4 5DNC ASN 27.8443
5 5DNC ASN 27.8443
6 5DNC ASN 27.8443
Pocket No.: 6; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 6pac.bio2) has 46 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: 6
This union binding pocket(no: 7) in the query (biounit: 6pac.bio2) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 5DNC ASN 27.8443
2 5DNC ASN 27.8443
3 5DNC ASN 27.8443
4 5DNC ASN 27.8443
5 5DNC ASN 27.8443
6 5DNC ASN 27.8443
Pocket No.: 8; Query (leader) PDB : 6PAC; Ligand: ASP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 6pac.bio2) has 47 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback