Receptor
PDB id Resolution Class Description Source Keywords
3kcg 1.7 Å EC: 3.4.21.22 CRYSTAL STRUCTURE OF THE ANTITHROMBIN-FACTOR IXA-PENTASACCHA COMPLEX HOMO SAPIENS MICHAELIS COMPLEX BLOOD COAGULATION CALCIUM DISULFIDE BONLIKE DOMAIN GLYCOPROTEIN HEMOPHILIA HYDROLASE PHARMACEUPROTEASE SECRETED SERINE PROTEASE SULFATION ZYMOGEN HEBINDING PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR THROMBOPHILIA HYDROLASE INHIBITOR
Ref.: MOLECULAR BASIS OF FACTOR IXA RECOGNITION BY HEPARIN-ACTIVATED ANTITHROMBIN REVEALED BY A 1.7-A OF THE TERNARY COMPLEX. PROC.NATL.ACAD.SCI.USA V. 107 645 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA H:500;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
MPD I:5276;
I:5277;
 Invalid;
Invalid;
 none;
none;
 submit data
118.174 C6 H14 O2 C[C@@...
NAG FUC A:1;
C:1;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
367.351 n/a O=C(N...
NAG NAG MAN B:1;
 Part of Protein;
 none;
 submit data
n/a n/a
Z9L Z9K GU6 GU1 Z9H D:1;
 Valid;
 none;
 submit data
1650.33 n/a S(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KCG 1.7 Å EC: 3.4.21.22 CRYSTAL STRUCTURE OF THE ANTITHROMBIN-FACTOR IXA-PENTASACCHA COMPLEX HOMO SAPIENS MICHAELIS COMPLEX BLOOD COAGULATION CALCIUM DISULFIDE BONLIKE DOMAIN GLYCOPROTEIN HEMOPHILIA HYDROLASE PHARMACEUPROTEASE SECRETED SERINE PROTEASE SULFATION ZYMOGEN HEBINDING PROTEASE INHIBITOR SERINE PROTEASE INHIBITOR THROMBOPHILIA HYDROLASE INHIBITOR
Ref.: MOLECULAR BASIS OF FACTOR IXA RECOGNITION BY HEPARIN-ACTIVATED ANTITHROMBIN REVEALED BY A 1.7-A OF THE TERNARY COMPLEX. PROC.NATL.ACAD.SCI.USA V. 107 645 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3KCG - Z9L Z9K GU6 GU1 Z9H n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3KCG - Z9L Z9K GU6 GU1 Z9H n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KCG - Z9L Z9K GU6 GU1 Z9H n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: Z9L Z9K GU6 GU1 Z9H; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 Z9L Z9K GU6 GU1 Z9H 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: Z9L Z9K GU6 GU1 Z9H; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KCG; Ligand: Z9L Z9K GU6 GU1 Z9H; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3kcg.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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