Receptor
PDB id Resolution Class Description Source Keywords
4ezd 2.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAUR TO SELENOUREA BOS TAURUS MEMBRANE PROTEIN CHANNEL UREA TRANSPORT SLC14 STRUCTURALGENOMICS PSI-BIOLOGY NEW YORK CONSORTIUM ON MEMBRANE PROTSTRUCTURE NYCOMPS TRANSPORT PROTEIN
Ref.: STRUCTURE AND PERMEATION MECHANISM OF A MAMMALIAN U TRANSPORTER. PROC.NATL.ACAD.SCI.USA V. 109 11194 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC A:403;
A:404;
B:403;
B:404;
B:405;
C:403;
C:404;
C:405;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
180.156 C6 H12 O6 C([C@...
BOG A:405;
A:406;
A:407;
B:406;
B:407;
C:406;
C:407;
C:408;
C:409;
C:410;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
292.369 C14 H28 O6 CCCCC...
SEY A:401;
A:402;
B:401;
B:402;
C:401;
C:402;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
 submit data
123.016 C H4 N2 Se C(=[S...
SPL A:408;
A:409;
B:408;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
425.688 C26 H51 N O3 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4EZD 2.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF THE UT-B UREA TRANSPORTER FROM BOS TAUR TO SELENOUREA BOS TAURUS MEMBRANE PROTEIN CHANNEL UREA TRANSPORT SLC14 STRUCTURALGENOMICS PSI-BIOLOGY NEW YORK CONSORTIUM ON MEMBRANE PROTSTRUCTURE NYCOMPS TRANSPORT PROTEIN
Ref.: STRUCTURE AND PERMEATION MECHANISM OF A MAMMALIAN U TRANSPORTER. PROC.NATL.ACAD.SCI.USA V. 109 11194 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 232 families.
1 4EZD - SEY C H4 N2 Se C(=[Se])(N....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 197 families.
1 4EZD - SEY C H4 N2 Se C(=[Se])(N....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 165 families.
1 4EZD - SEY C H4 N2 Se C(=[Se])(N....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SEY; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 SEY 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: SEY; Similar ligands found: 92
No: Ligand Similarity coefficient
1 ACM 1.0000
2 ACT 1.0000
3 AF3 0.9990
4 KCS 0.9971
5 BEF 0.9920
6 IPA 0.9900
7 78T 0.9890
8 2PO 0.9890
9 MCH 0.9638
10 ALA 0.9620
11 GLV 0.9537
12 VN4 0.9510
13 F50 0.9506
14 MGX 0.9496
15 GOA 0.9494
16 FAH 0.9483
17 NHY 0.9474
18 HAE 0.9471
19 AGU 0.9470
20 TSZ 0.9469
21 PPI 0.9461
22 NMU 0.9460
23 61G 0.9453
24 HVB 0.9447
25 AKR 0.9439
26 NIE 0.9405
27 F3V 0.9366
28 1BP 0.9361
29 GLY 0.9317
30 R3W 0.9311
31 2A1 0.9259
32 ATO 0.9258
33 2A3 0.9250
34 PZO 0.9249
35 TCV 0.9249
36 BRP 0.9247
37 CP2 0.9241
38 TRI 0.9215
39 HUH 0.9214
40 IMD 0.9209
41 N2O 0.9168
42 BXA 0.9159
43 SO2 0.9115
44 BRJ 0.9106
45 TMO 0.9103
46 AXO 0.9056
47 03S 0.9054
48 HP4 0.9023
49 GOL 0.9006
50 EDO 0.9003
51 ALF 0.9002
52 FPO 0.8981
53 CB0 0.8979
54 TBU 0.8978
55 BF4 0.8957
56 2HP 0.8949
57 MSM 0.8947
58 GB 0.8947
59 PXO 0.8922
60 NOE 0.8863
61 PO4 0.8863
62 J3K 0.8856
63 2PA 0.8826
64 BBX 0.8807
65 OSM 0.8800
66 MR3 0.8794
67 QPT 0.8793
68 WO6 0.8790
69 2MZ 0.8782
70 3MT 0.8777
71 3TR 0.8774
72 4MZ 0.8766
73 5MP 0.8765
74 FUS 0.8764
75 GXV 0.8763
76 1MZ 0.8762
77 5KX 0.8754
78 ES3 0.8712
79 ART 0.8708
80 3GR 0.8704
81 JZ6 0.8694
82 BYZ 0.8678
83 PYZ 0.8672
84 PEJ 0.8646
85 BAQ 0.8632
86 3ZS 0.8625
87 GBL 0.8622
88 9XN 0.8620
89 PYR 0.8576
90 6SP 0.8557
91 OXM 0.8550
92 OXL 0.8533
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4ezd.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4ezd.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4ezd.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4ezd.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4ezd.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4EZD; Ligand: SEY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4ezd.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
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