Receptor
PDB id Resolution Class Description Source Keywords
6o6v 2.35 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CSM6 IN COMPLEX WITH CA4 BY SOAKING CA4 THERMOCOCCUS ONNURINEUS TYPE III-A CRISPR-CAS SYSTEM; CSM6 IN COMPLEX WITH CA4 IMMUSYSTEM IMMUNE SYSTEM-DNA COMPLEX IMMUNE SYSTEM-RNA COMPLE
Ref.: CRISPR-CAS III-A CSM6 CARF DOMAIN IS A RING NUCLEAS TRIGGERING STEPWISE CA4CLEAVAGE WITH APA>P FORMATIO TERMINATING RNASE ACTIVITY. MOL.CELL V. 75 944 2019
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
A A A A D:1;
C:1;
 Valid;
Valid;
 none;
none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6O6Y 1.96 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF CSM6 IN COMPLEX WITH CYCLIC-TETRAADENYL BY COCRYSTALLIZATION OF CSM6 AND CA4 THERMOCOCCUS ONNURINEUS TYPE III-A CRISPR-CAS SYSTEM; CSM6 IN COMPLEX WITH CA4 BY COCRYSTALLIZATION OF CSM6 AND CA4 IMMUNE SYSTEM
Ref.: CRISPR-CAS III-A CSM6 CARF DOMAIN IS A RING NUCLEAS TRIGGERING STEPWISE CA4CLEAVAGE WITH APA>P FORMATIO TERMINATING RNASE ACTIVITY. MOL.CELL V. 75 944 2019
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6O70 - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
2 6O6X - A A A A n/a n/a
3 6O6Z - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
4 6O6V - A A A A n/a n/a
5 6O6Y - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6O70 - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
2 6O6X - A A A A n/a n/a
3 6O6Z - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
4 6O6V - A A A A n/a n/a
5 6O6Y - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6O70 - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
2 6O6X - A A A A n/a n/a
3 6O6Z - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
4 6O6V - A A A A n/a n/a
5 6O6Y - LQJ C20 H24 N10 O12 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: A A A A ; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: A A A A ; Similar ligands found: 1
No: Ligand Similarity coefficient
1 A A A A 1.0000
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6O6Y; Ligand: ACK; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6o6y.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6O6Y; Ligand: ACK; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6o6y.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6O6Y; Ligand: LQJ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 6o6y.bio1) has 45 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 6O6Y; Ligand: LQJ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 6o6y.bio1) has 45 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback