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Receptor
PDB id Resolution Class Description Source Keywords
2HXT 1.7 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF L-FUCONATE DEHYDRATASE FROM XANTHOMONAS CAMPESTRIS LIGANDED WITH MG++ AND D-ERYTHRONOHYDROXAMATE XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS L-FUCONATE DEHYDRATASE ENOLASE SUPERFAMILY D-ERYTHROMOHYDRUNKNOWN FUNCTION
Ref.: EVOLUTION OF ENZYMATIC ACTIVITIES IN THE ENOLASE SUPERFAMILY: L-FUCONATE DEHYDRATASE FROM XANTHOMONA CAMPESTRIS. BIOCHEMISTRY V. 45 14582 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EHM A:501;
Valid;
none;
submit data
151.118 C4 H9 N O5 C([C@...
MG A:601;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HXT 1.7 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF L-FUCONATE DEHYDRATASE FROM XANTHOMONAS CAMPESTRIS LIGANDED WITH MG++ AND D-ERYTHRONOHYDROXAMATE XANTHOMONAS CAMPESTRIS PV. CAMPESTRIS L-FUCONATE DEHYDRATASE ENOLASE SUPERFAMILY D-ERYTHROMOHYDRUNKNOWN FUNCTION
Ref.: EVOLUTION OF ENZYMATIC ACTIVITIES IN THE ENOLASE SUPERFAMILY: L-FUCONATE DEHYDRATASE FROM XANTHOMONA CAMPESTRIS. BIOCHEMISTRY V. 45 14582 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 46 families.
1 2HXT - EHM C4 H9 N O5 C([C@H]([C....
2 2HXU - LFC C6 H12 O6 C[C@@H]([C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 2HXT - EHM C4 H9 N O5 C([C@H]([C....
2 2HXU - LFC C6 H12 O6 C[C@@H]([C....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 2HXT - EHM C4 H9 N O5 C([C@H]([C....
2 2HXU - LFC C6 H12 O6 C[C@@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: EHM; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 EHM 1 1
2 RES 0.447368 0.765957
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HXT; Ligand: EHM; Similar sites found with APoc: 36
This union binding pocket(no: 1) in the query (biounit: 2hxt.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3LVW GSH 1.36054
2 2G50 PYR 1.5873
3 2WQP WQP 1.7192
4 1GQ2 OXL 2.04082
5 3VPD ANP 2.13523
6 4DXJ IPE 2.48619
7 5T7I LAT NAG GAL 3.22581
8 4C6F DOR 3.56234
9 4C6F NCD 3.56234
10 5LUN OGA 3.69318
11 5LUN ARG 3.69318
12 4UDK BMA 4.08163
13 4L9Z COA 4.12979
14 4L9Z OXL 4.12979
15 4YRD 3IT 4.45682
16 5T9C G3P 4.85075
17 5OD2 GLC 6.33188
18 1KKR 2AS 7.74818
19 1EC9 XYH 8.39002
20 2ZYI STE 8.61678
21 3DZ6 PUT 8.95522
22 1SR9 KIV 10.8844
23 3U6W KIV 11.2412
24 3CXO 3LR 13.7349
25 3CXO 1N5 13.7349
26 3HPF GAE 15.8568
27 3DGB MUC 16.4921
28 4OIT MAN 16.8142
29 2P8B NSK 19.2412
30 3UXL CFI 19.5822
31 1TKK ALA GLU 21.3115
32 2GGH NLQ 23.4667
33 3DG6 MUC 24.5232
34 2DW7 SRT 28.5714
35 3DER ALA LYS 30.4348
36 2QJN KDG 38.0597
Pocket No.: 2; Query (leader) PDB : 2HXT; Ligand: EHM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2hxt.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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