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Receptor
PDB id Resolution Class Description Source Keywords
2VK2 1.2 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF A GALACTOFURANOSE BINDING PROTEIN ESCHERICHIA COLI TRANSPORT PROTEIN ABC TRANSPORT GALACTOFURANOSE TRANSPORT PERIPLASM
Ref.: FURANOSE-SPECIFIC SUGAR TRANSPORT: CHARACTERIZATION OF A BACTERIAL GALACTOFURANOSE-BINDING PROTEIN. J.BIOL.CHEM. V. 284 31156 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GZL A:1298;
Valid;
none;
Kd = 0.13 uM
180.156 C6 H12 O6 C(C([...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VK2 1.2 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF A GALACTOFURANOSE BINDING PROTEIN ESCHERICHIA COLI TRANSPORT PROTEIN ABC TRANSPORT GALACTOFURANOSE TRANSPORT PERIPLASM
Ref.: FURANOSE-SPECIFIC SUGAR TRANSPORT: CHARACTERIZATION OF A BACTERIAL GALACTOFURANOSE-BINDING PROTEIN. J.BIOL.CHEM. V. 284 31156 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GZL; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 GZL 1 1
2 GMH 0.862069 0.866667
3 289 0.862069 0.866667
4 293 0.435897 0.83871
5 GTK 0.405405 0.7
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VK2; Ligand: GZL; Similar sites found with APoc: 80
This union binding pocket(no: 1) in the query (biounit: 2vk2.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2P1C GG3 1.30719
2 6BYM HC3 1.47783
3 5KOH HCA 1.63399
4 4L9Z COA 1.96078
5 5JJR 68E 1.96078
6 4OB6 S2T 1.96078
7 4X7Q 3YR 2.28758
8 1JS3 PLP 142 2.28758
9 6C4A PYR 2.61438
10 4MFL MFK 2.61438
11 3LDW ZOL 2.61438
12 1XPM CAA 2.61438
13 1EKX PAL 2.61438
14 4CYI ATP 2.94118
15 4WB7 ATP 2.94118
16 5GLN XYS 2.94118
17 4I94 ANP 3
18 4B5W PYR 3.125
19 5JNN 6LM 3.15789
20 3OJI PYV 3.1746
21 5GQI ATP 3.23887
22 5AWM ANP 3.26797
23 5JO1 6LM 3.26797
24 5X8I SQZ 3.26797
25 4CU7 GIF 3.26797
26 5MN0 A8S 3.34928
27 3NMV PYV 3.37079
28 5OJI ISN 3.46154
29 5OJI NAP 3.46154
30 5ENZ UDP 3.92157
31 4HMT NNV 4
32 4HMT FMN 4
33 5OYH T99 4.14508
34 4PIV 2W4 4.24837
35 6BGC BGC 4.24837
36 1GHE ACO 4.24837
37 6AYH C3G 4.47761
38 1DEK DGP 4.56432
39 5LI1 ANP 4.57516
40 2EG7 OTD 4.57516
41 1ZP9 ATP 4.65116
42 1ZTH ADP 4.65116
43 2Q0D ATP 4.81586
44 1PK8 ATP 4.90196
45 1N07 FMN 4.90798
46 4JWJ SAH 4.9505
47 5HZ9 5M8 5.18518
48 5K5M 68T 5.22876
49 5YSZ CBI 5.55556
50 2A1L PCW 5.55556
51 1ZH8 NAP 5.55556
52 6H21 UD1 5.55556
53 4F9C 0SX 6.25
54 4UX9 ANP 6.53595
55 5Z5I XYS 6.86275
56 5Z5I FUB 6.86275
57 4YHB FAD 6.95971
58 1RQJ RIS 7.02341
59 6C6O ENG 7.18954
60 3RE4 TO1 8.16993
61 4BH1 SIA GAL NAG 9.63855
62 1G8K MGD 9.77444
63 6BXI ANP 10.4575
64 1I7L ATP 10.6796
65 6GNF QPS 11.1111
66 1N62 MCN 11.4458
67 4LZJ 22H 11.5512
68 5LXT GTP 11.8881
69 2P9H IPT 12.2677
70 2JLD AG1 14.7059
71 9ABP GLA 15.6863
72 9ABP GAL 15.6863
73 4IMG NGF 19.1126
74 1RPJ ALL 25.6944
75 3O75 F1X 26.8382
76 5XSS XYP 27.451
77 3MA0 XYP 29.7386
78 2GBP BGC 30.3922
79 5APG EEM 34.0541
80 2IOY RIP 48.4099
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