Receptor
PDB id Resolution Class Description Source Keywords
2VK2 1.2 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF A GALACTOFURANOSE BINDING PROTEIN ESCHERICHIA COLI TRANSPORT PROTEIN ABC TRANSPORT GALACTOFURANOSE TRANSPORT PERIPLASM
Ref.: FURANOSE-SPECIFIC SUGAR TRANSPORT: CHARACTERIZATION OF A BACTERIAL GALACTOFURANOSE-BINDING PROTEIN. J.BIOL.CHEM. V. 284 31156 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GZL A:1298;
Valid;
none;
Kd = 0.13 uM
180.156 C6 H12 O6 C(C([...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VK2 1.2 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF A GALACTOFURANOSE BINDING PROTEIN ESCHERICHIA COLI TRANSPORT PROTEIN ABC TRANSPORT GALACTOFURANOSE TRANSPORT PERIPLASM
Ref.: FURANOSE-SPECIFIC SUGAR TRANSPORT: CHARACTERIZATION OF A BACTERIAL GALACTOFURANOSE-BINDING PROTEIN. J.BIOL.CHEM. V. 284 31156 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 141 families.
1 2VK2 Kd = 0.13 uM GZL C6 H12 O6 C(C([C@H]1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GZL; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 GZL 1 1
2 289 0.862069 0.866667
3 GMH 0.862069 0.866667
4 293 0.435897 0.83871
5 GTK 0.405405 0.7
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VK2; Ligand: GZL; Similar sites found: 19
This union binding pocket(no: 1) in the query (biounit: 2vk2.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2P1C GG3 0.02852 0.41073 1.30719
2 5KOH HCA 0.01019 0.4027 1.63399
3 5JNN 6LM 0.02841 0.4029 3.15789
4 5JO1 6LM 0.008117 0.42766 3.26797
5 3NMV PYV 0.02172 0.40056 3.37079
6 1GHE ACO 0.02862 0.40374 4.24837
7 5LI1 ANP 0.0168 0.4129 4.57516
8 4YHB FAD 0.02599 0.40873 6.95971
9 3MVH WFE 0.02334 0.41559 7.18954
10 3NCQ ATP 0.04495 0.41221 11.7647
11 2P9H IPT 0.0001147 0.45218 12.2677
12 9ABP GAL 0.0007216 0.47734 15.6863
13 9ABP GLA 0.0007216 0.40141 15.6863
14 1RPJ ALL 0.000007662 0.52285 25.6944
15 3O75 F1X 0.0003094 0.42344 26.8382
16 5XSS XYP 0.008539 0.40253 27.451
17 3MA0 XYP 0.000107 0.47359 29.7386
18 2GBP BGC 0.00001041 0.45751 30.3922
19 2IOY RIP 0.00000001131 0.69819 48.4099
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