Receptor
PDB id Resolution Class Description Source Keywords
4YOE 1.92 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF UP1 BOUND TO RNA 5'-AGU-3' HOMO SAPIENS HNRNPA1 ALTERNATIVE SPLICING PROTEIN-RNA RECOGNITION RNA PROTEIN-RNA COMPLEX
Ref.: THE FIRST CRYSTAL STRUCTURE OF THE UP1 DOMAIN OF HN BOUND TO RNA REVEALS A NEW LOOK FOR AN OLD RNA BIND PROTEIN. J.MOL.BIOL. V. 427 3241 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:301;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
SO4 A:302;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
A G U E:15;
Valid;
Atoms found LESS than expected: % Diff = 0.061;
submit data
916.604 n/a [P+](...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YOE 1.92 Å NON-ENZYME: TRANSCRIPT_TRANSLATE STRUCTURE OF UP1 BOUND TO RNA 5'-AGU-3' HOMO SAPIENS HNRNPA1 ALTERNATIVE SPLICING PROTEIN-RNA RECOGNITION RNA PROTEIN-RNA COMPLEX
Ref.: THE FIRST CRYSTAL STRUCTURE OF THE UP1 DOMAIN OF HN BOUND TO RNA REVEALS A NEW LOOK FOR AN OLD RNA BIND PROTEIN. J.MOL.BIOL. V. 427 3241 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 4YOE - A G U n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 4YOE - A G U n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 4YOE - A G U n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: A G U ; Similar ligands found: 100
No: Ligand ECFP6 Tc MDL keys Tc
1 A G U 1 1
2 U G A 0.854962 1
3 A U 0.801653 0.936709
4 G A A A 0.769841 0.962025
5 U A A U 0.75188 0.925
6 A U C C 0.737226 0.962025
7 U A G G 0.723077 0.949367
8 G C 0.694656 0.987342
9 APC G U 0.674074 0.901235
10 G G G C 0.640288 0.975
11 A G C C 0.635714 0.974684
12 G C C C 0.618056 0.9625
13 U A C C 0.614286 0.949367
14 G U34 0.605839 0.975
15 OMC OMU OMG OMG U 0.594771 0.951219
16 APU 0.57971 0.9125
17 G G 0.576923 0.949367
18 G G G RPC 0.574468 0.962025
19 4TC 0.572464 0.86747
20 UP5 0.569343 0.888889
21 G3A 0.532847 0.91358
22 U2G 0.531469 0.950617
23 G5P 0.528986 0.91358
24 A A 0.526316 0.8625
25 G G U 0.52518 0.925
26 UPA 0.517483 0.901235
27 ATP A A A 0.510949 0.873418
28 PUA 0.5 0.857143
29 G3D 0.488722 0.876543
30 UCG 0.487179 0.925926
31 A A A 0.485294 0.829268
32 U U 0.481203 0.8125
33 GPC 0.480263 0.916667
34 3GP 0.47619 0.8875
35 GDP BEF 0.473684 0.869048
36 G4P 0.470588 0.876543
37 GDP MG 0.466165 0.890244
38 CG2 0.463576 0.950617
39 BEF GDP 0.463235 0.858824
40 ALF 5GP 0.462687 0.858824
41 PAX 0.459119 0.848837
42 0O2 0.457143 0.876543
43 139 0.456954 0.869048
44 DG DA DC DG 0.45614 0.939759
45 DA DC DG DA 0.453488 0.939759
46 DC DG DA DC 0.452381 0.915663
47 G 0.446154 0.9
48 5GP 0.446154 0.9
49 A3P 0.445312 0.8375
50 GDP AF3 0.442857 0.858824
51 GTP MG 0.442029 0.890244
52 DT DA DC DG 0.441989 0.895349
53 GP2 0.440298 0.857143
54 DC DG DT DA 0.43956 0.895349
55 3PD UM3 0.437909 0.926829
56 PAP 0.43609 0.82716
57 CSQ 0.433566 0.819277
58 CSV 0.433566 0.819277
59 GDP ALF 0.432624 0.858824
60 GDP 0.42963 0.888889
61 0WD 0.429487 0.86747
62 SFB 0.427632 0.736842
63 GCP 0.427536 0.86747
64 GPG 0.426573 0.925926
65 UDP UDP 0.425197 0.797468
66 GDD 0.424658 0.902439
67 GKE 0.424658 0.902439
68 GDC 0.424658 0.902439
69 G2P 0.42446 0.857143
70 UDP GAL 0.42446 0.802469
71 DC DG 0.423077 0.927711
72 DU DU DU DU BRU DG DU 0.422619 0.875
73 1YD 0.421769 0.8875
74 4BW 0.421769 0.8875
75 BEF ADP 0.421053 0.809524
76 ADP BEF 0.421053 0.809524
77 3AM 0.420635 0.825
78 JBT 0.418719 0.757576
79 GCP G 0.41844 0.901235
80 G1R G1R 0.417178 0.914634
81 GNH 0.416058 0.878049
82 U U U U 0.416058 0.8
83 PPS 0.416058 0.744444
84 GSP 0.414286 0.847059
85 ADP MG 0.413534 0.829268
86 DA DU DG DA 0.412903 0.870588
87 GP3 0.411765 0.91358
88 UPU 0.410448 0.8
89 GTP 0.410072 0.888889
90 GAV 0.408451 0.857143
91 GDP 7MG 0.406667 0.925926
92 DU DU DU DU BRU DA DU 0.405882 0.818182
93 GMP 0.404762 0.825
94 UDP ALA FGA CYS DAL DAL MUB C C A9Z 0.403226 0.810526
95 ADP BMA 0.402778 0.864198
96 4TA 0.402516 0.848837
97 G2R 0.4 0.857143
98 U5P 0.4 0.7875
99 GMV 0.4 0.86747
100 ANP MG 0.4 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
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