Receptor
PDB id Resolution Class Description Source Keywords
2GH4 1.9 Å EC: 3.2.1.- YTER/D143N/DGALA-RHA BACILLUS SUBTILIS ALPHA / ALPHA BARREL HYDROLASE
Ref.: STRUCTURE OF UNSATURATED RHAMNOGALACTURONYL HYDROLA COMPLEXED WITH SUBSTRATE BIOCHEM.BIOPHYS.RES.COMMUN. V. 347 1021 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
RAM GAD B:1;
 Valid;
 none;
 submit data
321.258 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2D8L 1.7 Å EC: 3.2.1.- CRYSTAL STRUCTURE OF UNSATURATED RHAMNOGALACTURONYL HYDROLAS COMPLEX WITH DGLCA-GALNAC BACILLUS SUBTILIS UNSATURATED RHAMNOGALACTURONYL HYDROLASE HYDROLASE
Ref.: A NOVEL GLYCOSIDE HYDROLASE FAMILY 105: THE STRUCTU FAMILY 105 UNSATURATED RHAMNOGALACTURONYL HYDROLASE COMPLEXED WITH A DISACCHARIDE IN COMPARISON WITH FA ENZYME COMPLEXED WITH THE DISACCHARIDE J.MOL.BIOL. V. 360 573 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2GH4 - RAM GAD n/a n/a
2 2D8L - NGA GCD n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2GH4 - RAM GAD n/a n/a
2 2D8L - NGA GCD n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2GH4 - RAM GAD n/a n/a
2 2D8L - NGA GCD n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: RAM GAD; Similar ligands found: 10
No: Ligand ECFP6 Tc MDL keys Tc
1 RAM GAD 1 1
2 GTR RAM AQA 0.589041 0.96875
3 LGU MAW 0.560606 0.9375
4 MAV LGU MAV BEM 0.493333 0.909091
5 GCU MAV MAW 0.493333 0.909091
6 NAG GAD 0.486842 0.632653
7 BGC RAM BGC GAD 0.471264 0.794872
8 NDG GCD 0.468354 0.632653
9 83Y BDP 83Y GCD 0.461538 0.612245
10 RAM ADA RAM 0.438356 0.875
Similar Ligands (3D)
Ligand no: 1; Ligand: RAM GAD; Similar ligands found: 20
No: Ligand Similarity coefficient
1 GLC DMJ 0.9109
2 GLC GLC 0.9073
3 GLC IFM 0.9070
4 MAN GLC 0.8979
5 GAL GLA 0.8949
6 7D1 MAN 0.8941
7 MAN MNM 0.8906
8 GLC 7LQ 0.8892
9 XYP GCU 0.8890
10 MAN G63 0.8875
11 GTR AQA 0.8846
12 BDF GLC 0.8811
13 GDQ GLC 0.8809
14 FRU GLC 0.8783
15 ADA AQA 0.8659
16 GLC GLA 0.8640
17 BMA GLA 0.8633
18 BGC GLA 0.8567
19 MAN IFM 0.8564
20 EGA GLA 0.8546
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2D8L; Ligand: NGA GCD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2d8l.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback