Receptor
PDB id Resolution Class Description Source Keywords
4O1P 2.5 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PN SUS SCROFA ANKYRIN REPEAT-KINASE-RNASE RNA CLEAVAGE 2-5A TRANSFERASEHYDROLASE
Ref.: DIMERIC STRUCTURE OF PSEUDOKINASE RNASE L BOUND TO REVEALS A BASIS FOR INTERFERON-INDUCED ANTIVIRAL AC MOL.CELL V. 53 221 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP B:901;
C:901;
D:901;
A:901;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:903;
B:902;
C:903;
D:902;
D:903;
A:902;
B:903;
C:902;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
25L C:904;
D:904;
A:904;
B:904;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
1165.59 C30 H40 N15 O25 P5 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4O1P 2.5 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF RNASE L IN COMPLEX WITH 2-5A AND AMP-PN SUS SCROFA ANKYRIN REPEAT-KINASE-RNASE RNA CLEAVAGE 2-5A TRANSFERASEHYDROLASE
Ref.: DIMERIC STRUCTURE OF PSEUDOKINASE RNASE L BOUND TO REVEALS A BASIS FOR INTERFERON-INDUCED ANTIVIRAL AC MOL.CELL V. 53 221 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 4O1P - 25L C30 H40 N15 O25 P5 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 4OAV - PO4 PO4 A A A A PO4 n/a n/a
2 4O1P - 25L C30 H40 N15 O25 P5 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 4OAV - PO4 PO4 A A A A PO4 n/a n/a
2 4O1P - 25L C30 H40 N15 O25 P5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Ligand no: 2; Ligand: 25L; Similar ligands found: 322
No: Ligand ECFP6 Tc MDL keys Tc
1 25L 1 1
2 25A 0.862069 0.985915
3 ATP 0.809524 0.985915
4 HEJ 0.809524 0.985915
5 A22 0.808989 1
6 5FA 0.8 0.985915
7 AQP 0.8 0.985915
8 B4P 0.752941 0.985915
9 AP5 0.752941 0.985915
10 BA3 0.741176 0.985915
11 ADP 0.732558 0.985915
12 AGS 0.730337 0.933333
13 SAP 0.730337 0.933333
14 A2D 0.717647 0.985915
15 ATR 0.711111 0.957747
16 6YZ 0.691489 0.958904
17 AN2 0.685393 0.972222
18 A2R 0.666667 0.972222
19 AT4 0.666667 0.945946
20 AR6 0.663043 0.958333
21 APR 0.663043 0.958333
22 ACQ 0.659574 0.958904
23 TAT 0.659574 0.945946
24 T99 0.659574 0.945946
25 M33 0.659341 0.945205
26 AD9 0.655914 0.958904
27 ACP 0.652174 0.958904
28 ADQ 0.646465 0.958904
29 AMP 0.643678 0.957747
30 A 0.643678 0.957747
31 ANP 0.642105 0.958904
32 NA7 0.633663 0.945946
33 A2P 0.626374 0.943662
34 ITT 0.623656 0.930556
35 ADX 0.623656 0.8625
36 CA0 0.623656 0.932432
37 9X8 0.617647 0.907895
38 OAD 0.617647 0.932432
39 50T 0.617021 0.945205
40 A3R 0.613861 0.896104
41 ATF 0.612245 0.945946
42 APC 0.610526 0.945946
43 PRX 0.610526 0.881579
44 7D4 0.606383 0.893333
45 ABM 0.604396 0.905405
46 SRA 0.6 0.906667
47 A1R 0.598039 0.896104
48 UPA 0.59292 0.921053
49 AP2 0.591398 0.945946
50 A12 0.591398 0.945946
51 3OD 0.590476 0.932432
52 BIS 0.590476 0.921053
53 5AL 0.585859 0.918919
54 G5P 0.581818 0.934211
55 HFD 0.581633 0.933333
56 UP5 0.575221 0.933333
57 SRP 0.574257 0.894737
58 AU1 0.572917 0.958904
59 5SV 0.572816 0.8375
60 G3A 0.572727 0.934211
61 PAP 0.571429 0.971831
62 PAJ 0.567308 0.873418
63 4AD 0.567308 0.907895
64 GTA 0.5625 0.898734
65 00A 0.561905 0.896104
66 2A5 0.561224 0.906667
67 PTJ 0.560748 0.884615
68 8QN 0.557692 0.918919
69 OOB 0.557692 0.945205
70 OMR 0.556522 0.841463
71 RBY 0.555556 0.92
72 ADV 0.555556 0.92
73 ADP PO3 0.555556 0.930556
74 NJP 0.554622 0.959459
75 AFH 0.553571 0.897436
76 AMO 0.552381 0.92
77 AP0 0.551724 0.909091
78 NPW 0.550847 0.898734
79 NDP 0.550847 0.934211
80 2AM 0.549451 0.930556
81 MAP 0.548077 0.933333
82 NAX 0.547826 0.886076
83 NAI 0.547826 0.921053
84 AHX 0.54717 0.884615
85 DLL 0.54717 0.945205
86 A4P 0.547009 0.855422
87 FYA 0.546296 0.918919
88 1ZZ 0.546296 0.829268
89 TXP 0.546219 0.934211
90 NZQ 0.546219 0.922078
91 3AT 0.544554 0.958333
92 ADP BMA 0.542056 0.932432
93 3UK 0.542056 0.932432
94 ODP 0.541667 0.922078
95 AR6 AR6 0.539823 0.931507
96 T5A 0.537815 0.853659
97 LMS 0.537634 0.817073
98 WAQ 0.537037 0.871795
99 LAD 0.537037 0.85
100 B5V 0.537037 0.92
101 PR8 0.537037 0.839506
102 DQV 0.535088 0.972222
103 TXD 0.534483 0.921053
104 6V0 0.534483 0.909091
105 ADP ALF 0.533981 0.858974
106 ALF ADP 0.533981 0.858974
107 TXA 0.53211 0.92
108 NB8 0.53211 0.884615
109 ME8 0.53211 0.829268
110 OVE 0.531915 0.893333
111 7D3 0.53125 0.893333
112 SON 0.530612 0.92
113 TXE 0.529915 0.921053
114 DTP 0.529412 0.893333
115 V3L 0.529412 0.958333
116 GAP 0.529412 0.881579
117 ADP VO4 0.528846 0.918919
118 VO4 ADP 0.528846 0.918919
119 PO4 PO4 A A A A PO4 0.527778 0.916667
120 48N 0.525862 0.884615
121 139 0.525 0.886076
122 XNP 0.52459 0.886076
123 ADN 0.523256 0.833333
124 XYA 0.523256 0.833333
125 RAB 0.523256 0.833333
126 9SN 0.522523 0.884615
127 DND 0.521368 0.945946
128 NXX 0.521368 0.945946
129 DAL AMP 0.518868 0.893333
130 FA5 0.517857 0.92
131 B5Y 0.517857 0.907895
132 B5M 0.517857 0.907895
133 YAP 0.517857 0.907895
134 7DT 0.514852 0.971831
135 9ZA 0.514019 0.896104
136 9ZD 0.514019 0.896104
137 XAH 0.513274 0.829268
138 4TC 0.512605 0.909091
139 ADJ 0.512397 0.864198
140 COD 0.512195 0.802326
141 1DG 0.511628 0.934211
142 DG1 0.511628 0.934211
143 A3P 0.510204 0.957747
144 A A 0.509091 0.958333
145 4UV 0.508772 0.907895
146 CNA 0.508197 0.945946
147 5AS 0.50505 0.770115
148 ATP A A A 0.504425 0.944444
149 LAQ 0.504274 0.829268
150 TYM 0.504202 0.92
151 80F 0.504 0.853659
152 DDS 0.5 0.866667
153 GA7 0.5 0.92
154 4UU 0.5 0.907895
155 4UW 0.495798 0.873418
156 PPS 0.495238 0.8625
157 6AD 0.495238 0.897436
158 AOC 0.494845 0.810811
159 3AM 0.494737 0.916667
160 NAP 0.492308 0.958904
161 F2R 0.491935 0.853659
162 RGT 0.491228 0.945946
163 JB6 0.491071 0.896104
164 TAP 0.48855 0.921053
165 YLP 0.487395 0.809524
166 MYR AMP 0.486726 0.807229
167 NA0 0.484848 0.945946
168 7L1 0.484848 0.786517
169 TYR AMP 0.482759 0.883117
170 5N5 0.477778 0.808219
171 AV2 0.476636 0.905405
172 NMN AMP PO4 0.47619 0.883117
173 NAD 0.47619 0.945205
174 G5A 0.47619 0.770115
175 0WD 0.47619 0.934211
176 YLC 0.47541 0.829268
177 YLB 0.47541 0.809524
178 ARG AMP 0.474576 0.819277
179 7MD 0.474576 0.851852
180 EAD 0.473684 0.886076
181 7D5 0.473684 0.866667
182 A4D 0.472527 0.808219
183 5CD 0.472527 0.794521
184 SSA 0.472222 0.790698
185 128 0.471074 0.788235
186 A3D 0.46875 0.932432
187 IOT 0.467742 0.821429
188 AHZ 0.466667 0.807229
189 GPG 0.464912 0.922078
190 BTX 0.464567 0.831325
191 YLA 0.464 0.809524
192 TSB 0.463636 0.809524
193 A5A 0.462963 0.797619
194 DAT 0.461538 0.893333
195 AYB 0.460317 0.8
196 P1H 0.459854 0.864198
197 APU 0.459677 0.907895
198 AVV 0.459459 0.884615
199 GTP 0.458716 0.907895
200 TAD 0.458333 0.873418
201 AMP DBH 0.457627 0.906667
202 EP4 0.457447 0.74359
203 CO7 0.457143 0.795455
204 7DD 0.456311 0.971831
205 NSS 0.455357 0.790698
206 62F 0.455172 0.875
207 VMS 0.454545 0.77907
208 52H 0.454545 0.770115
209 NAE 0.454545 0.907895
210 54H 0.454545 0.77907
211 N01 0.453846 0.918919
212 3DH 0.453608 0.763158
213 M2T 0.452632 0.725
214 DTA 0.452632 0.8
215 7MC 0.451613 0.831325
216 NVA LMS 0.451327 0.744444
217 NAQ 0.451128 0.884615
218 LPA AMP 0.45082 0.807229
219 8X1 0.45045 0.744444
220 5CA 0.45045 0.790698
221 53H 0.45045 0.770115
222 BT5 0.449612 0.821429
223 HDV 0.449541 0.881579
224 MTA 0.447917 0.763158
225 ZID 0.447761 0.932432
226 5X8 0.447619 0.753247
227 ENP 0.447368 0.906667
228 LEU LMS 0.447368 0.744444
229 IMO 0.445545 0.916667
230 6FA 0.443662 0.853659
231 AF3 ADP 3PG 0.443548 0.82716
232 P5A 0.443478 0.736264
233 FB0 0.442857 0.795455
234 NAJ PZO 0.442748 0.860759
235 LSS 0.442478 0.752809
236 DSZ 0.442478 0.790698
237 G A A A 0.44186 0.884615
238 6RE 0.44 0.75
239 NDE 0.438849 0.945946
240 ARU 0.438596 0.85
241 DZD 0.438462 0.897436
242 FAS 0.4375 0.864198
243 FAD 0.4375 0.864198
244 N0B 0.437037 0.831325
245 MAO 0.436893 0.75
246 M24 0.43609 0.8625
247 YLY 0.43609 0.8
248 6C6 0.435185 0.87013
249 NDC 0.432624 0.884615
250 U A 0.431818 0.921053
251 J7C 0.431373 0.759494
252 A3N 0.431373 0.776316
253 KAA 0.431034 0.744444
254 GSU 0.431034 0.770115
255 ZAS 0.43 0.75641
256 NAJ PYZ 0.42963 0.819277
257 ETB 0.428571 0.823529
258 DCA 0.428571 0.813953
259 SFD 0.427586 0.744681
260 9K8 0.42735 0.725275
261 S4M 0.427184 0.659091
262 FDA 0.426573 0.845238
263 N6P 0.426087 0.929577
264 YSA 0.425 0.790698
265 MGP 0.423423 0.873418
266 2SA 0.423423 0.92
267 FAY 0.422819 0.875
268 A A A 0.422414 0.893333
269 COA 0.422222 0.813953
270 0T1 0.422222 0.813953
271 DSH 0.421569 0.716049
272 WSA 0.420635 0.8
273 RFL 0.42 0.833333
274 A G 0.419847 0.896104
275 4TA 0.419847 0.819277
276 AMP NAD 0.419847 0.918919
277 6G0 0.419643 0.873418
278 U A G G 0.416667 0.896104
279 8PZ 0.416667 0.811765
280 PUA 0.414815 0.897436
281 A U 0.414062 0.883117
282 GJV 0.413462 0.740741
283 COS 0.413043 0.795455
284 CAO 0.413043 0.786517
285 AMX 0.413043 0.823529
286 30N 0.413043 0.744681
287 ZDA 0.412844 0.853333
288 GSP 0.412281 0.8625
289 3KK 0.411348 0.795455
290 4YB 0.41129 0.772727
291 PGS 0.411215 0.871795
292 CMX 0.410072 0.813953
293 SCO 0.410072 0.813953
294 V1N 0.409836 0.931507
295 71V 0.409524 0.896104
296 GP3 0.409091 0.934211
297 9JJ 0.409091 0.875
298 GEK 0.408696 0.728395
299 OXK 0.408451 0.795455
300 CA6 0.408451 0.721649
301 12D 0.408 0.797619
302 A3G 0.407767 0.789474
303 NEC 0.407767 0.736842
304 SFG 0.407407 0.74026
305 FAM 0.407143 0.795455
306 ACO 0.407143 0.786517
307 FCX 0.407143 0.786517
308 MGO 0.40708 0.85
309 FNK 0.406667 0.816092
310 GDP 0.405405 0.907895
311 6IA 0.405405 0.82716
312 PRT 0.404959 0.918919
313 HAX 0.404255 0.795455
314 2MC 0.402778 0.76087
315 5AD 0.402174 0.736111
316 A7D 0.401869 0.766234
317 AAT 0.401786 0.698795
318 FYN 0.401408 0.813953
319 IVC 0.4 0.804598
320 SA8 0.4 0.698795
321 GGZ 0.4 0.814815
322 A5D 0.4 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4O1P; Ligand: ANP; Similar sites found with APoc: 26
This union binding pocket(no: 1) in the query (biounit: 4o1p.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 5WNL STU 4.38596
2 2WU6 DKI 4.98688
3 4QTB 38Z 5.78947
4 5EFQ ADP 7.20461
5 3RWP ABQ 8.03859
6 4BFM ANP 8.08383
7 4CFU 2WC 8.25082
8 2Z7R STU 8.41121
9 4CLI 5P8 9.17431
10 3E8N ATP 12.9032
11 3E8N VRA 12.9032
12 3SLS ANP 14.4737
13 3FC2 IBI 15.5224
14 1PHK ATP 16.7785
15 1U5R ATP 17.2414
16 3BU5 ATP 17.6471
17 1IR3 ANP 17.6471
18 3TKI S25 17.9567
19 3PLS ANP 19.1275
20 5X8I SQZ 20.5202
21 5HCY 60D 20.5438
22 6F3G CJN 21.0169
23 5XVG 8FX 22.8669
24 2VN9 GVD 23.2558
25 5LXM ADP 34.2105
26 2RIO ADP 36.6359
Pocket No.: 2; Query (leader) PDB : 4O1P; Ligand: 25L; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4o1p.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4O1P; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4o1p.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4O1P; Ligand: 25L; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4o1p.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4O1P; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4o1p.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4O1P; Ligand: 25L; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4o1p.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 4O1P; Ligand: 25L; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 4o1p.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 4O1P; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 4o1p.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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