Receptor
PDB id Resolution Class Description Source Keywords
1G9F 2.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE SOYBEAN AGGLUTININ IN A COMPLEX WIT BIANTENNARY BLOOD GROUP ANTIGEN ANALOG GLYCINE MAX JELLY-ROLL FOLD LEGUME LECTIN SUGAR BINDING PROTEIN
Ref.: WEAK PROTEIN-PROTEIN INTERACTIONS IN LECTINS: THE C STRUCTURE OF A VEGETATIVE LECTIN FROM THE LEGUME DO BIFLORUS. J.MOL.BIOL. V. 309 193 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:255;
 Part of Protein;
 none;
 submit data
40.078 Ca [Ca+2...
GAL NAG GAL NAG GAL C:1;
 Valid;
 none;
 submit data
910.826 n/a O=C(N...
MN A:254;
 Part of Protein;
 none;
 submit data
54.938 Mn [Mn+2...
NAG NAG B:1;
 Part of Protein;
 none;
 submit data
408.404 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1G9F 2.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE SOYBEAN AGGLUTININ IN A COMPLEX WIT BIANTENNARY BLOOD GROUP ANTIGEN ANALOG GLYCINE MAX JELLY-ROLL FOLD LEGUME LECTIN SUGAR BINDING PROTEIN
Ref.: WEAK PROTEIN-PROTEIN INTERACTIONS IN LECTINS: THE C STRUCTURE OF A VEGETATIVE LECTIN FROM THE LEGUME DO BIFLORUS. J.MOL.BIOL. V. 309 193 2001
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 1G9F - GAL NAG GAL NAG GAL n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 3WCS - MAN NAG GAL n/a n/a
2 3WOG - MAN NAG n/a n/a
3 1G9F - GAL NAG GAL NAG GAL n/a n/a
50% Homology Family (67)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 322 families.
1 5T55 Kd = 0.68 nM BGC GAL GLA NGA n/a n/a
2 5T54 Kd = 0.87 nM GLA FUC A2G n/a n/a
3 5T5J Kd = 0.73 nM ACA SER SER VAL GLY A2G n/a n/a
4 5T52 Kd = 0.54 nM NGA C8 H15 N O6 CC(=O)N[C@....
5 5T5L Kd = 0.73 nM ACE SER SER VAL GLY A2G n/a n/a
6 5T5P Kd = 0.71 nM ACE SER THR VAL GLY A2G n/a n/a
7 1FNZ - A2G C8 H15 N O6 CC(=O)N[C@....
8 1S1A - MMA MAN n/a n/a
9 2ARB Ka = 26000 M^-1 MAN NAG n/a n/a
10 1N3Q - FRU GLC n/a n/a
11 2AR6 Ka = 63000 M^-1 MAN MAN MAN NAG NAG n/a n/a
12 1N3O - GYP C7 H14 O6 CO[C@@H]1[....
13 1N3P - GLC FRU n/a n/a
14 2ARX - MAN MAN n/a n/a
15 2ARE Ka = 1900 M^-1 MAN C6 H12 O6 C([C@@H]1[....
16 1LED - MAG GAL FUC FUC n/a n/a
17 1GSL - MAG FUC GAL FUC n/a n/a
18 1V00 - BGC GAL n/a n/a
19 3N3H - CIT C6 H8 O7 C(C(=O)O)C....
20 3N36 - GLA C6 H12 O6 C([C@@H]1[....
21 1AX0 Ka = 1340 M^-1 A2G C8 H15 N O6 CC(=O)N[C@....
22 1UZY - BGC GAL n/a n/a
23 1LTE - BGC GAL n/a n/a
24 1AX1 Ka = 1940 M^-1 BGC GAL n/a n/a
25 1AX2 Ka = 9730 M^-1 NDG GAL n/a n/a
26 1GZC Kd = 0.32 mM BGC GAL n/a n/a
27 3N35 - A2G C8 H15 N O6 CC(=O)N[C@....
28 1AXZ Ka = 1570 M^-1 GAL C6 H12 O6 C([C@@H]1[....
29 1GZ9 Kd = 0.31 mM BGC GAL FUC n/a n/a
30 3ZYR Kd = 4.6 uM NAG ASN NAG BMA MAN MAN NAG NAG n/a n/a
31 3ZVX - MAN MAN MAN n/a n/a
32 5U38 - MMA MAN n/a n/a
33 5KXE Kd = 5.45 uM 6Y2 C22 H31 N3 O13 CC(=O)N[C@....
34 5KXB - NGA C8 H15 N O6 CC(=O)N[C@....
35 5KXC - 6Y2 C22 H31 N3 O13 CC(=O)N[C@....
36 5KXD - 6Y2 C22 H31 N3 O13 CC(=O)N[C@....
37 4WV8 - GLC GAL n/a n/a
38 4U2A - A2G C8 H15 N O6 CC(=O)N[C@....
39 4U36 - SER A2G n/a n/a
40 1JXN - MFU C7 H14 O5 C[C@H]1[C@....
41 3WCS - MAN NAG GAL n/a n/a
42 3WOG - MAN NAG n/a n/a
43 5EYX - MMA MAN n/a n/a
44 5EYY - MMA MAN n/a n/a
45 2BQP - GLC C6 H12 O6 C([C@@H]1[....
46 5T7P - XMM C14 H15 Br Cl N O6 c1cc(c(c2c....
47 2DVA - MGC GAL n/a n/a
48 6VC4 Kd = 360 uM QWG C22 H37 N3 O14 S2 CO[C@@H]1[....
49 6VGF Kd = 180 uM WA3 C42 H68 N6 O27 S4 c1c(nnn1C[....
50 2DV9 - GAL GAL n/a n/a
51 1V6K - GLC GAL n/a n/a
52 1V6L - BGC GAL n/a n/a
53 2DVD - GAL GAL n/a n/a
54 6VC3 Kd = 482 uM QWJ C15 H24 O9 S2 C#CCSC[C@@....
55 2TEP - NGA GAL n/a n/a
56 6V95 Kd = 495 uM QSG C32 H48 N10 O20 c1c(nnn1[C....
57 6VAV Kd = 690 uM QTY C32 H48 N10 O16 c1c(nnn1[C....
58 2DVB - GAL C6 H12 O6 C([C@@H]1[....
59 1V6I - GLC GAL n/a n/a
60 6VAW Kd = 1563 uM S3W C20 H33 N5 O12 CO[C@@H]1[....
61 2PEL Ki = 1.37 mM BGC GAL n/a n/a
62 1G9F - GAL NAG GAL NAG GAL n/a n/a
63 2DTW - 2GS C7 H14 O6 CO[C@@H]1[....
64 1WBL - AMG C7 H14 O6 CO[C@@H]1[....
65 2ZMK - EGA GLA n/a n/a
66 2D3S - SER A2G n/a n/a
67 2FMD - MAN MAN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GAL NAG GAL NAG GAL; Similar ligands found: 144
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL NAG GAL NAG GAL 1 1
2 GAL NAG GAL 0.925373 0.9375
3 NAG GAL NAG GAL NAG GAL 0.810811 0.979592
4 NAG GAL NAG GAL 0.810811 1
5 BGC FUC GAL NAG GAL 0.75 0.958333
6 NAG NAG BMA MAN 0.710843 0.923077
7 MAN NAG GAL 0.684211 0.9375
8 NAG GAL GAL 0.68 0.9375
9 BGC GAL GLA NGA 0.679012 0.9375
10 BGC GAL NAG NAG GAL GAL 0.670455 1
11 BMA MAN NAG 0.666667 0.9375
12 NAG GAL NAG 0.658228 1
13 BGC GAL NAG 0.658228 0.9375
14 BGC GAL GLA NGA GAL 0.650602 0.9375
15 BGC BGC BGC 0.647059 0.6875
16 BGC BGC BGC BGC BGC BGC BGC 0.647059 0.6875
17 BGC BGC BGC BGC BGC BGC 0.647059 0.6875
18 BGC BGC BGC BGC BGC 0.647059 0.6875
19 GLC BGC BGC BGC 0.647059 0.6875
20 BGC GAL NAG GAL 0.641975 0.9375
21 NAG NAG MAN MAN MAN 0.633333 1
22 NAG NAG BMA 0.621951 0.923077
23 NAG NAG BMA MAN NAG 0.617977 0.979592
24 BMA MAN MAN NAG GAL NAG 0.617021 1
25 GAL NGA A2G 0.615385 1
26 GAL NAG FUC GAL 0.611765 0.958333
27 NAG BMA MAN MAN NAG GAL NAG GAL 0.59375 0.979592
28 BGC FUC GAL NAG 0.58427 0.958333
29 NAG GAL 0.581081 0.9375
30 C4W NAG FUC BMA MAN 0.575758 0.923077
31 GAL GLA 0.573529 0.6875
32 NDG BMA MAN MAN NAG GAL NAG 0.564356 0.979592
33 BGC GAL NGA GAL 0.559524 0.9375
34 NAG NAG BMA MAN MAN NAG GAL NAG 0.558824 0.979592
35 BGC BGC BGC BGC BGC BGC BGC BGC 0.558442 0.6875
36 NAG NAG BMA BMA 0.550562 0.888889
37 NAG NAG NAG NAG NAG 0.55 0.979592
38 NDG NAG NAG NAG NAG 0.55 0.979592
39 NAG NAG NAG NAG NAG NAG NAG NAG 0.55 0.979592
40 NAG NAG NAG NAG NAG NAG 0.55 0.979592
41 BGC GAL NGA 0.548781 0.9375
42 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.548077 1
43 BGC GAL GLA 0.546667 0.6875
44 TVD GAL 0.539474 0.979592
45 GLA NAG GAL FUC 0.539326 0.958333
46 NAG NAG BMA MAN MAN MAN MAN 0.537736 0.923077
47 BGC GAL NAG GAL FUC 0.536842 0.958333
48 BGC BGC BGC BGC 0.536585 0.6875
49 GAL NAG GAL FUC FUC 0.532609 0.938776
50 BGC GAL NAG GAL FUC FUC 0.530612 0.938776
51 BGC GAL NAG GAL SIA 0.526316 0.90566
52 GLC GAL NAG GAL FUC GLA 0.525253 0.958333
53 A2G GAL 0.519481 0.9375
54 MBG NAG 0.518987 0.938776
55 NAG GAL NAG GAL SIA 0.517544 0.90566
56 NAG NAG NAG TMX 0.517241 0.827586
57 NAG BMA MAN MAN MAN MAN 0.515789 0.9375
58 GLC GAL NAG GAL FUC A2G 0.514563 0.979592
59 NAG NAG FUL BMA MAN MAN NAG GAL 0.508929 0.90566
60 NAG NAG NAG NAG 0.505747 0.90566
61 NAG NAG NAG NAG NAG NAG NAG 0.505747 0.90566
62 NAG NAG NAG 0.505747 0.90566
63 NDG BMA MAN MAN NAG MAN MAN 0.5 1
64 C4W NAG FUC BMA 0.5 0.923077
65 NAG GAL BGC GAL 0.5 0.9375
66 GDL NAG 0.5 1
67 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.485149 0.9375
68 1GN ACY GAL 1GN BGC ACY GAL BGC 0.484536 1
69 Z4S NAG NAG 0.483516 0.90566
70 NAG BMA 0.481481 0.846154
71 MGC GAL 0.481013 0.938776
72 NAG BMA MAN MAN MAN MAN MAN MAN MAN MAN 0.480392 0.9375
73 MAN MAN MAN NAG NAG 0.478723 1
74 NAG NAG BMA MAN MAN NAG NAG 0.477064 0.90566
75 MBG A2G 0.47561 0.938776
76 NAG GAL FUC GLA 0.468085 0.958333
77 NAG NOJ NAG 0.467391 0.872727
78 NAG NOJ NAG NAG 0.467391 0.857143
79 C4W NAG FUC BMA MAN MAN NAG GAL NAG 0.466667 0.827586
80 C4W NAG FUC BMA MAN MAN NAG 0.466102 0.923077
81 MMA MAN NAG 0.465909 0.938776
82 NAG G6S 0.465909 0.71875
83 A2G NAG 0.463415 1
84 MAN BMA BMA BMA BMA BMA BMA 0.460526 0.6875
85 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.460526 0.6875
86 GLC GLC GLC GLC BGC GLC GLC 0.460526 0.6875
87 GAL NAG GAL SIA 0.459459 0.90566
88 MAN MAN MAN GLC 0.457831 0.6875
89 MAN NAG 0.45679 0.9375
90 MBG GAL 0.453333 0.693878
91 BGC FUC GAL FUC A2G 0.44898 0.938776
92 A2G GAL NAG 0.445652 1
93 BGC GAL FUC A2G 0.444444 0.958333
94 GAL FUC A2G 0.444444 0.958333
95 BMA MAN MAN 0.439024 0.6875
96 C4W NAG FUC BMA MAN NAG GAL 0.438596 0.827586
97 NAG FUC GAL 0.438202 0.958333
98 NAG NGT NAG 0.4375 0.813559
99 GCU BGC 0.4375 0.673469
100 GAL NGA 0.435294 0.88
101 MGL GAL 0.434211 0.693878
102 BGC GAL GLA NGA GAL SIA 0.433333 0.923077
103 BGC GLA GAL 0.432432 0.6875
104 NAG GCU NAG GCD 0.431193 0.888889
105 Z3Q NGA 0.430108 0.813559
106 GLC BGC FUC GAL 0.428571 0.708333
107 BGC FUC GAL 0.428571 0.708333
108 A2G SER GAL 0.428571 0.903846
109 MAN BMA BMA 0.426829 0.66
110 C4W NAG FUC BMA MAN MAN NAG NAG 0.425 0.923077
111 AMV NAG AMU NAG 0.424242 0.941176
112 FUC GAL 0.423077 0.6875
113 GAL 1GN BGC ACY GAL 1GN BGC ACY GAL 6PZ 0.421875 0.872727
114 NAG ASN NAG BMA MAN MAN NAG NAG 0.420168 0.872727
115 ALA ASN LYS NAG NAG BMA MAN MAN NAG NAG 0.420168 0.888889
116 A2G MBN GAL 0.419355 0.9
117 NDG NAG 0.418605 0.979592
118 NAG GAL FUC A2G 0.417582 0.958333
119 8VW 0.415842 0.90566
120 LOG GAL 0.413793 0.793103
121 G2F BGC BGC BGC BGC BGC 0.411765 0.622642
122 AO3 0.411765 0.738462
123 NAA AMI NAA 0.411765 0.738462
124 BGC RAM BGC GAD 0.411765 0.673077
125 3QL 0.411111 0.923077
126 GLA NAG FUC GAL 0.41 0.938776
127 GAL NAG FUC GAL SIA 0.409836 0.923077
128 G2F SHG BGC BGC 0.409639 0.634615
129 UMG 0.409524 0.857143
130 NOK GAL 0.409091 0.789474
131 A2G THR GAL 0.408602 0.941176
132 MAN MAN NAG 0.408602 0.9
133 6Y2 0.408163 0.75
134 GAL 2NA NAG 0.407407 0.833333
135 NAG BDP NAG BDP NAG BDP NAG 0.405941 0.96
136 NDG GAL 0.404762 0.704918
137 GLC BGC BGC 0.404494 0.693878
138 GAL A2G MBN 0.404255 0.882353
139 YZ0 MAN MAN NAG MAN 0.403846 0.938776
140 RAM MAN GLA ABE RAM MAN GLA ABE 0.401869 0.686275
141 NDG GLA NAG GLC RAM 0.401786 0.979592
142 NDG NAG GLA NAG GLC RAM 0.401786 0.979592
143 BDP NPO NDG BDP NDG 0.401786 0.75
144 C4W NAG FUC BMA MAN NAG 0.401709 0.923077
Similar Ligands (3D)
Ligand no: 1; Ligand: GAL NAG GAL NAG GAL; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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