Receptor
PDB id Resolution Class Description Source Keywords
5EWC 1.75 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE HUMAN BRPF1 BROMODOMAIN IN COMPLEX SEED17 HOMO SAPIENS BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 1(BRPF1) MONOLEUKEMIA ZINC-FINGER (MOZ) INHIBITOR TRANSCRIPTION DNA BPROTEIN
Ref.: TWENTY CRYSTAL STRUCTURES OF BROMODOMAIN AND PHD FI CONTAINING PROTEIN 1 (BRPF1)/LIGAND COMPLEXES REVEA CONSERVED BINDING MOTIFS AND RARE INTERACTIONS. J.MED.CHEM. V. 59 5555 2016
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NO3 A:802;
 Invalid;
 none;
 submit data
62.005 N O3 [N+](...
5SJ A:801;
 Valid;
 none;
 submit data
234.251 C12 H14 N2 O3 CCOC(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4UYE 1.65 Å NON-ENZYME: OTHER BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-DIMETHYL-2-OXO-6-( PIPERIDIN-1-YL)-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-5-YL-2- M ETHOXYBENZAMIDE HOMO SAPIENS TRANSCRIPTION INHIBITOR HISTONE EPIGENETIC READER ANTAGO
Ref.: 1,3-DIMETHYL BENZIMIDAZOLONES ARE POTENT, SELECTIVE INHIBITORS OF THE BRPF1 BROMODOMAIN. ACS MED.CHEM.LETT. V. 5 1190 2014
Members (37)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 5E3G - 5JQ C5 H4 N4 O2 S C12=C(NC(=....
2 5T4U ic50 = 4800 nM 12Q C10 H9 N O CN1c2ccccc....
3 5EWH Kd = 170 uM 5SG C9 H7 N O c1cc2cnccc....
4 5C85 Kd = 105 uM 4YO C8 H7 Br N2 O c1cc2c(cc1....
5 5E3D Kd = 95 uM 5JL C5 H4 N4 O S2 C12=C(NC(=....
6 5C87 - 4YS C9 H7 N O c1ccc2c(c1....
7 5O4T - 9KT C10 H10 N2 O2 CN1c2ccccc....
8 5OV8 Kd = 18 uM AXN C24 H30 N4 O4 S CC(C)Cc1cc....
9 5O4S ic50 = 3.4 uM 9KW C24 H28 N4 O5 S CN1c2cc(c(....
10 5MWH Kd = 1.8 uM UWX C24 H30 N4 O5 S CC(C)Cc1cc....
11 5DY7 - 5GT C9 H7 F3 N2 O c1cc2c(cc1....
12 5T4V ic50 = 60 nM N48 C19 H17 N3 O4 S CC1=CC(=O)....
13 5DYC - 5GU C8 H7 Br N2 O c1cc2c(cc1....
14 5O55 - 9L5 C19 H23 N5 O2 CCN1c2ccc(....
15 5EQ1 Kd = 21 uM BEA C9 H8 N3 S Cc1cccc2c1....
16 5G4S ic50 = 1 uM 8VI C24 H31 N5 O3 CCN(c1cc2c....
17 5EWC - 5SJ C12 H14 N2 O3 CCOC(=O)c1....
18 5EPR Kd = 91 uM 5QY C9 H10 N2 O C[C@H]1C(=....
19 5EVA - 5S9 C11 H9 F2 N3 O Cn1c(ccn1)....
20 5ETD - 5RN C10 H9 N O CC(=O)c1c[....
21 5DYA - 5GV C11 H12 N2 O3 CC[C@@H]1C....
22 5EV9 - 5SB C14 H12 N4 O CC(=O)Nc1c....
23 5MYG Kd = 31 nM LS8 C19 H17 N3 O4 S CC1=Cc2cc(....
24 5MWZ Kd = 7.1 uM KGU C24 H36 N6 O3 CCN1c2cc(c....
25 5G4R ic50 = 7.943 nM LF1 C22 H27 N5 O3 C[C@@H]1CN....
26 5OWA Kd = 3.5 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
27 5EM3 - 5Q0 C9 H7 N O c1cc2c(ccc....
28 5ETB Kd = 29 uM 5RO C11 H11 N O Cc1cccc2c1....
29 4UYE Kd = 9.54 nM 9F9 C22 H26 N4 O3 CN1c2cc(c(....
30 5O5F - 9LT C22 H20 F N5 O3 CCN1c2ccc(....
31 5O5A - 9LN C22 H21 N5 O3 CCN1c2ccc(....
32 5O5H - 9LK C17 H14 Cl N3 O3 Cc1c(oc(n1....
33 5C7N Kd = 0.27 uM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
34 5EPS Kd = 38 uM 5QX C9 H10 N2 O CN1c2ccccc....
35 5MWG ic50 = 1.7 uM WGX C25 H30 N4 O4 S CN1c2cc(c(....
36 5D7X Kd = 15 uM XZ8 C14 H13 N3 O2 CC1=C(C(=O....
37 6EKQ Kd = 10.9 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
70% Homology Family (39)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 5E3G - 5JQ C5 H4 N4 O2 S C12=C(NC(=....
2 5T4U ic50 = 4800 nM 12Q C10 H9 N O CN1c2ccccc....
3 5EWH Kd = 170 uM 5SG C9 H7 N O c1cc2cnccc....
4 5C85 Kd = 105 uM 4YO C8 H7 Br N2 O c1cc2c(cc1....
5 5E3D Kd = 95 uM 5JL C5 H4 N4 O S2 C12=C(NC(=....
6 5C87 - 4YS C9 H7 N O c1ccc2c(c1....
7 5O4T - 9KT C10 H10 N2 O2 CN1c2ccccc....
8 5OV8 Kd = 18 uM AXN C24 H30 N4 O4 S CC(C)Cc1cc....
9 5O4S ic50 = 3.4 uM 9KW C24 H28 N4 O5 S CN1c2cc(c(....
10 5MWH Kd = 1.8 uM UWX C24 H30 N4 O5 S CC(C)Cc1cc....
11 5DY7 - 5GT C9 H7 F3 N2 O c1cc2c(cc1....
12 5T4V ic50 = 60 nM N48 C19 H17 N3 O4 S CC1=CC(=O)....
13 5DYC - 5GU C8 H7 Br N2 O c1cc2c(cc1....
14 5O55 - 9L5 C19 H23 N5 O2 CCN1c2ccc(....
15 5EQ1 Kd = 21 uM BEA C9 H8 N3 S Cc1cccc2c1....
16 5G4S ic50 = 1 uM 8VI C24 H31 N5 O3 CCN(c1cc2c....
17 5EWC - 5SJ C12 H14 N2 O3 CCOC(=O)c1....
18 5EPR Kd = 91 uM 5QY C9 H10 N2 O C[C@H]1C(=....
19 5EVA - 5S9 C11 H9 F2 N3 O Cn1c(ccn1)....
20 5ETD - 5RN C10 H9 N O CC(=O)c1c[....
21 5DYA - 5GV C11 H12 N2 O3 CC[C@@H]1C....
22 5EV9 - 5SB C14 H12 N4 O CC(=O)Nc1c....
23 5MYG Kd = 31 nM LS8 C19 H17 N3 O4 S CC1=Cc2cc(....
24 5MWZ Kd = 7.1 uM KGU C24 H36 N6 O3 CCN1c2cc(c....
25 5G4R ic50 = 7.943 nM LF1 C22 H27 N5 O3 C[C@@H]1CN....
26 5OWA Kd = 3.5 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
27 5EM3 - 5Q0 C9 H7 N O c1cc2c(ccc....
28 5ETB Kd = 29 uM 5RO C11 H11 N O Cc1cccc2c1....
29 4UYE Kd = 9.54 nM 9F9 C22 H26 N4 O3 CN1c2cc(c(....
30 5O5F - 9LT C22 H20 F N5 O3 CCN1c2ccc(....
31 5O5A - 9LN C22 H21 N5 O3 CCN1c2ccc(....
32 5O5H - 9LK C17 H14 Cl N3 O3 Cc1c(oc(n1....
33 5C7N Kd = 0.27 uM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
34 5EPS Kd = 38 uM 5QX C9 H10 N2 O CN1c2ccccc....
35 5MWG ic50 = 1.7 uM WGX C25 H30 N4 O4 S CN1c2cc(c(....
36 5D7X Kd = 15 uM XZ8 C14 H13 N3 O2 CC1=C(C(=O....
37 6EKQ Kd = 10.9 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
38 3RCW - MB3 C5 H9 N O CN1CCCC1=O
39 5N49 ic50 = 450 nM 8LW C22 H17 N3 O3 Cc1cc2c(cc....
50% Homology Family (64)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 5I7Y Kd = 52 nM 69G C20 H21 N3 O2 C/C=C/CN1C....
2 4UIW ic50 = 0.00000001 M H1B C22 H22 F3 N3 O3 S2 CCN1C=C(c2....
3 4UIV ic50 = 0.00000001 M XZB C21 H20 F3 N3 O3 S2 CN1C=C(c2c....
4 5JI8 Kd = 23.4 uM 6KT C8 H7 N3 O S c1cc2c(cc1....
5 5MKY ic50 = 2 uM I0D C15 H17 Cl N4 O CN1CCc2c(c....
6 4UIU ic50 = 0.00000001 M TVU C22 H24 N2 O6 S2 CN1C=C(c2c....
7 4UIT ic50 = 0.00000001 M N1D C22 H25 N3 O6 S2 CN1C=C(c2c....
8 5I40 ic50 = 13.7 uM 67N C8 H8 N2 O CN1C=Cc2cc....
9 5I7X Kd = 53 nM 67B C17 H17 N3 O2 CN1C=C(c2c....
10 6V1B Kd = 37 nM H1B C22 H22 F3 N3 O3 S2 CCN1C=C(c2....
11 6V0X Kd = 277 uM B49 C22 H27 F N4 O2 CCN(CC)CCN....
12 4XY8 Kd = 397 nM 43U C12 H10 Br N5 O COc1ccc(cc....
13 5IGM Kd = 41.7 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
14 4Z6H Kd = 612 nM 4L2 C16 H18 N2 O2 CC1=CC(=O)....
15 6HM0 Kd = 73 nM GBW C50 H64 N8 O9 S Cc1c(scn1)....
16 5F1H Kd = 14.1 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
17 5F1L ic50 = 21 nM 5U2 C19 H24 N2 O4 CC1=CC(=CN....
18 5F25 Kd = 9.1 uM 5TU C14 H14 N2 O2 CC1=CC(=CN....
19 4Z6I - 4L3 C27 H31 N3 O4 CC1=CC(=O)....
20 6V0S Kd = 16000 nM EAE C13 H15 N O2 S CCN1c2cc(c....
21 5EU1 Kd = 15.4 nM 5SW C20 H23 N3 O3 CN1C=C(c2c....
22 6V14 Kd = 82 nM QMG C20 H19 N3 O2 Cc1ccc(cc1....
23 5F2P Kd = 37.5 uM 5TY C10 H12 N4 O CN1C=Cc2c(....
24 5E3D Kd = 95 uM 5JL C5 H4 N4 O S2 C12=C(NC(=....
25 5C87 - 4YS C9 H7 N O c1ccc2c(c1....
26 5O4T - 9KT C10 H10 N2 O2 CN1c2ccccc....
27 5OV8 Kd = 18 uM AXN C24 H30 N4 O4 S CC(C)Cc1cc....
28 5O4S ic50 = 3.4 uM 9KW C24 H28 N4 O5 S CN1c2cc(c(....
29 5MWH Kd = 1.8 uM UWX C24 H30 N4 O5 S CC(C)Cc1cc....
30 5DY7 - 5GT C9 H7 F3 N2 O c1cc2c(cc1....
31 5T4V ic50 = 60 nM N48 C19 H17 N3 O4 S CC1=CC(=O)....
32 5DYC - 5GU C8 H7 Br N2 O c1cc2c(cc1....
33 5O55 - 9L5 C19 H23 N5 O2 CCN1c2ccc(....
34 5EQ1 Kd = 21 uM BEA C9 H8 N3 S Cc1cccc2c1....
35 5G4S ic50 = 1 uM 8VI C24 H31 N5 O3 CCN(c1cc2c....
36 5EWC - 5SJ C12 H14 N2 O3 CCOC(=O)c1....
37 5EPR Kd = 91 uM 5QY C9 H10 N2 O C[C@H]1C(=....
38 5EVA - 5S9 C11 H9 F2 N3 O Cn1c(ccn1)....
39 5ETD - 5RN C10 H9 N O CC(=O)c1c[....
40 5DYA - 5GV C11 H12 N2 O3 CC[C@@H]1C....
41 5EV9 - 5SB C14 H12 N4 O CC(=O)Nc1c....
42 5MYG Kd = 31 nM LS8 C19 H17 N3 O4 S CC1=Cc2cc(....
43 5MWZ Kd = 7.1 uM KGU C24 H36 N6 O3 CCN1c2cc(c....
44 5G4R ic50 = 7.943 nM LF1 C22 H27 N5 O3 C[C@@H]1CN....
45 5OWA Kd = 3.5 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
46 5EM3 - 5Q0 C9 H7 N O c1cc2c(ccc....
47 5ETB Kd = 29 uM 5RO C11 H11 N O Cc1cccc2c1....
48 4UYE Kd = 9.54 nM 9F9 C22 H26 N4 O3 CN1c2cc(c(....
49 5O5F - 9LT C22 H20 F N5 O3 CCN1c2ccc(....
50 5O5A - 9LN C22 H21 N5 O3 CCN1c2ccc(....
51 5O5H - 9LK C17 H14 Cl N3 O3 Cc1c(oc(n1....
52 5C7N Kd = 0.27 uM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
53 5EPS Kd = 38 uM 5QX C9 H10 N2 O CN1c2ccccc....
54 5MWG ic50 = 1.7 uM WGX C25 H30 N4 O4 S CN1c2cc(c(....
55 5D7X Kd = 15 uM XZ8 C14 H13 N3 O2 CC1=C(C(=O....
56 6EKQ Kd = 10.9 uM B0H C17 H24 N4 O2 S Cc1c(oc(n1....
57 6V1E Kd = 121 nM 5SW C20 H23 N3 O3 CN1C=C(c2c....
58 6V17 Kd = 148 nM H1B C22 H22 F3 N3 O3 S2 CCN1C=C(c2....
59 6V0Q Kd = 4200 nM EAE C13 H15 N O2 S CCN1c2cc(c....
60 6V1H Kd = 114 nM BMF C17 H20 N6 O4 S CCOC(=O)Nc....
61 6V16 Kd = 556 nM QMG C20 H19 N3 O2 Cc1ccc(cc1....
62 6V1F Kd = 418 nM 5U6 C20 H23 N3 O3 CN1C=C(c2c....
63 3RCW - MB3 C5 H9 N O CN1CCCC1=O
64 5N49 ic50 = 450 nM 8LW C22 H17 N3 O3 Cc1cc2c(cc....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 5SJ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 5SJ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 5SJ; Similar ligands found: 432
No: Ligand Similarity coefficient
1 J38 0.9508
2 RSV 0.9302
3 4CN 0.9291
4 YZ9 0.9286
5 OLU 0.9267
6 5GV 0.9259
7 YE6 0.9247
8 H4B 0.9243
9 JCZ 0.9234
10 M78 0.9233
11 H2B 0.9195
12 N1E 0.9192
13 7EH 0.9176
14 BIO 0.9173
15 NPS 0.9164
16 TRP 0.9161
17 YE7 0.9158
18 HBI 0.9154
19 QIV 0.9145
20 S98 0.9134
21 NPX 0.9128
22 PIQ 0.9127
23 1EB 0.9114
24 8CC 0.9111
25 T1N 0.9110
26 P4L 0.9108
27 4AU 0.9106
28 X2M 0.9105
29 9KZ 0.9102
30 7AP 0.9101
31 0OK 0.9101
32 1DR 0.9095
33 EES 0.9093
34 S0D 0.9089
35 1FE 0.9088
36 7FU 0.9082
37 2P3 0.9081
38 AJ1 0.9077
39 PRL 0.9075
40 F40 0.9075
41 NK5 0.9072
42 KLS 0.9071
43 2JX 0.9066
44 ASE 0.9063
45 2J1 0.9063
46 TCR 0.9062
47 5V7 0.9060
48 M4N 0.9055
49 4I8 0.9053
50 397 0.9052
51 5NN 0.9052
52 TFM 0.9049
53 TMG 0.9048
54 0XR 0.9045
55 2WU 0.9044
56 0DF 0.9043
57 0UL 0.9041
58 WV7 0.9040
59 7G2 0.9037
60 1V4 0.9037
61 ITE 0.9033
62 6FB 0.9030
63 BHS 0.9024
64 XCG 0.9022
65 BQ2 0.9021
66 2PK 0.9017
67 ZRK 0.9014
68 4UM 0.9012
69 6ZW 0.9009
70 HRM 0.9008
71 9NB 0.9007
72 5GT 0.9006
73 2FX 0.9005
74 RYV 0.9003
75 DX2 0.9003
76 1ZC 0.9001
77 4AB 0.8999
78 KMY 0.8998
79 NDD 0.8990
80 FHV 0.8989
81 2PV 0.8988
82 G14 0.8986
83 2GQ 0.8985
84 X0U 0.8985
85 Y3L 0.8984
86 ZSP 0.8977
87 WLH 0.8976
88 HNT 0.8975
89 5OR 0.8974
90 FBC 0.8972
91 D2G 0.8969
92 0SY 0.8967
93 1XS 0.8967
94 3VX 0.8966
95 RKY 0.8964
96 4ZF 0.8964
97 6DQ 0.8958
98 OA1 0.8957
99 39Z 0.8957
100 ODK 0.8956
101 1V3 0.8954
102 833 0.8954
103 5TT 0.8952
104 ZYQ 0.8951
105 WG8 0.8951
106 AJG 0.8948
107 N91 0.8947
108 E3X 0.8946
109 BXS 0.8946
110 GO2 0.8946
111 47V 0.8944
112 3N0 0.8944
113 RYY 0.8942
114 II4 0.8940
115 2LW 0.8940
116 22T 0.8938
117 JVD 0.8936
118 7L4 0.8935
119 52F 0.8931
120 5AD 0.8928
121 CUE 0.8927
122 GNG 0.8926
123 5C1 0.8922
124 363 0.8922
125 M83 0.8919
126 27K 0.8919
127 TID 0.8917
128 5VU 0.8917
129 ZHA 0.8915
130 5B2 0.8912
131 F02 0.8910
132 CSN 0.8908
133 J1K 0.8908
134 JAH 0.8908
135 6DH 0.8905
136 NY4 0.8905
137 TXW 0.8905
138 A7H 0.8904
139 1Q4 0.8904
140 Z25 0.8904
141 JP2 0.8903
142 MPU 0.8903
143 IS2 0.8899
144 MKN 0.8896
145 FF2 0.8895
146 7MW 0.8893
147 LUM 0.8891
148 8YH 0.8891
149 NAL 0.8889
150 NEO 0.8889
151 2QU 0.8888
152 EEK 0.8888
153 D87 0.8886
154 2QV 0.8886
155 0NJ 0.8884
156 5S9 0.8882
157 3VQ 0.8881
158 VUP 0.8878
159 4NP 0.8878
160 PMM 0.8878
161 5E5 0.8877
162 C4E 0.8873
163 MD6 0.8872
164 FQX 0.8872
165 CX6 0.8871
166 JMG 0.8871
167 EST 0.8871
168 1OT 0.8868
169 BGU 0.8866
170 5ER 0.8864
171 S60 0.8864
172 HRD 0.8863
173 EZL 0.8862
174 EYY 0.8862
175 Z21 0.8855
176 KW7 0.8855
177 OTA 0.8852
178 3W6 0.8852
179 3W3 0.8852
180 856 0.8852
181 H75 0.8851
182 657 0.8850
183 A5Q 0.8850
184 NEU 0.8847
185 28A 0.8847
186 BIK 0.8846
187 7KE 0.8845
188 9JT 0.8845
189 3VS 0.8844
190 LIG 0.8839
191 3D1 0.8838
192 LR8 0.8837
193 PQM 0.8837
194 14N 0.8836
195 2UD 0.8836
196 ZEA 0.8835
197 FCW 0.8834
198 KLE 0.8833
199 72D 0.8831
200 ZEC 0.8830
201 0FR 0.8829
202 6SD 0.8828
203 OQC 0.8827
204 LI7 0.8826
205 BX4 0.8825
206 6KT 0.8825
207 A8D 0.8824
208 1AJ 0.8823
209 TJM 0.8820
210 IBP 0.8819
211 TIA 0.8819
212 8V8 0.8819
213 CC5 0.8818
214 XG1 0.8818
215 6P3 0.8815
216 IOP 0.8814
217 KLV 0.8812
218 D80 0.8812
219 A9B 0.8811
220 57D 0.8811
221 0ON 0.8809
222 0LA 0.8806
223 ZRL 0.8804
224 E6Q 0.8804
225 ZZA 0.8803
226 4MB 0.8803
227 5H6 0.8802
228 ET0 0.8802
229 PUE 0.8798
230 IQ5 0.8795
231 DXK 0.8795
232 FMC 0.8794
233 CX4 0.8793
234 5F1 0.8793
235 LFN 0.8792
236 BIH 0.8791
237 S0A 0.8790
238 B61 0.8789
239 FYR 0.8789
240 HBO 0.8789
241 NRA 0.8788
242 EYJ 0.8788
243 DT7 0.8787
244 801 0.8786
245 LR2 0.8785
246 120 0.8784
247 JMM 0.8781
248 GJP 0.8779
249 5WT 0.8777
250 GOE 0.8777
251 D9Z 0.8776
252 BMC 0.8774
253 FCD 0.8773
254 N4E 0.8771
255 96Z 0.8771
256 G30 0.8770
257 P4T 0.8770
258 VFG 0.8765
259 EUH 0.8762
260 S0E 0.8761
261 E1K 0.8760
262 C53 0.8760
263 RKN 0.8759
264 4NS 0.8759
265 4FC 0.8759
266 HHS 0.8757
267 HH6 0.8754
268 RDV 0.8753
269 A5H 0.8753
270 SU9 0.8751
271 SWX 0.8749
272 G1L 0.8747
273 SLS 0.8746
274 KWV 0.8744
275 EQU 0.8742
276 PIC 0.8741
277 N2M 0.8740
278 DRG 0.8736
279 8XL 0.8734
280 OPA 0.8733
281 C0V 0.8732
282 V1T 0.8731
283 PNP 0.8730
284 VC3 0.8730
285 BP7 0.8730
286 JBZ 0.8729
287 B15 0.8728
288 7O4 0.8727
289 C09 0.8727
290 3D8 0.8726
291 1CE 0.8725
292 CKA 0.8724
293 30G 0.8723
294 6H2 0.8723
295 VFM 0.8722
296 JFS 0.8722
297 SJK 0.8721
298 3L1 0.8721
299 AVX 0.8720
300 KU1 0.8719
301 E1T 0.8717
302 9CE 0.8716
303 SKF 0.8716
304 PQS 0.8716
305 PQV 0.8715
306 IQZ 0.8713
307 4Z9 0.8712
308 X48 0.8710
309 1BW 0.8708
310 XIF XYP 0.8708
311 G2V 0.8706
312 92O 0.8704
313 A6Z 0.8704
314 MUX 0.8703
315 MN QAY 0.8703
316 I2E 0.8702
317 DX7 0.8702
318 0JD 0.8702
319 EUE 0.8701
320 GJG 0.8701
321 BMZ 0.8700
322 P7V 0.8699
323 9BF 0.8698
324 BA5 0.8694
325 6MW 0.8692
326 5WK 0.8692
327 L15 0.8691
328 2QC 0.8690
329 PTB 0.8689
330 2JK 0.8689
331 4BX 0.8688
332 FC2 0.8683
333 0F3 0.8682
334 CR4 0.8682
335 A6W 0.8681
336 ZYC 0.8680
337 O9Q 0.8678
338 0J2 0.8677
339 15N 0.8677
340 QUB 0.8676
341 LZ5 0.8675
342 SNV 0.8675
343 ADN 0.8674
344 78Y 0.8671
345 124 0.8671
346 5TY 0.8671
347 9ZE 0.8670
348 0FK 0.8670
349 4BL 0.8669
350 LOT 0.8665
351 EQA 0.8663
352 FZM 0.8659
353 ARJ 0.8657
354 NQ8 0.8656
355 6VW 0.8656
356 AQN 0.8653
357 JY2 0.8651
358 2K8 0.8651
359 D25 0.8650
360 XYP XIF 0.8649
361 K3D 0.8649
362 RDT 0.8648
363 MR6 0.8648
364 AXX 0.8648
365 DAH 0.8648
366 5WN 0.8647
367 WDW 0.8647
368 NFZ 0.8646
369 OUG 0.8642
370 4FF 0.8642
371 THA 0.8641
372 LO1 0.8634
373 STX 0.8633
374 4GU 0.8629
375 JYE 0.8628
376 5XL 0.8623
377 QNM 0.8621
378 RCV 0.8620
379 ANF 0.8619
380 3DE 0.8618
381 B5A 0.8616
382 N5B 0.8615
383 LC1 0.8614
384 BGN 0.8613
385 HA6 0.8612
386 4HB 0.8611
387 NQ7 0.8610
388 2JP 0.8605
389 B21 0.8603
390 549 0.8603
391 4BY 0.8602
392 AH3 0.8602
393 RBV 0.8602
394 LWA 0.8600
395 A4D 0.8598
396 D26 0.8597
397 122 0.8596
398 IDZ 0.8595
399 8NB 0.8594
400 5CD 0.8594
401 EAT 0.8590
402 2L1 0.8590
403 4RU 0.8589
404 JF8 0.8589
405 OUA 0.8587
406 2D2 0.8584
407 108 0.8583
408 5FD 0.8576
409 5BX 0.8575
410 JA5 0.8575
411 COL 0.8575
412 D8Q 0.8574
413 121 0.8571
414 5N5 0.8568
415 VFJ 0.8566
416 LTN 0.8564
417 1Q1 0.8555
418 RUG 0.8551
419 UNJ 0.8548
420 3R4 0.8547
421 ERZ 0.8543
422 39R 0.8541
423 ZIP 0.8540
424 27B 0.8539
425 14X 0.8539
426 Z3R 0.8536
427 GZV 0.8535
428 EE8 0.8531
429 XYP XDN 0.8527
430 4JE 0.8521
431 NIR 0.8520
432 109 0.8513
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4UYE; Ligand: 9F9; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 4uye.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 4YC9 4C1 35.5932
2 6J3O B4L 38.1356
3 5MLJ 9ST 40.1786
4 5ML0 P2L 45.4545
Pocket No.: 2; Query (leader) PDB : 4UYE; Ligand: 9F9; Similar sites found with APoc: 7
This union binding pocket(no: 2) in the query (biounit: 4uye.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6J3P B8O 38.1356
2 6J3O B4L 38.1356
3 6J3P B8O 38.1356
4 5TPX 7H7 38.9831
5 5MLJ 9ST 40.1786
6 5MLJ 9ST 40.1786
7 5ML0 P2L 45.4545
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