Receptor
PDB id Resolution Class Description Source Keywords
5XZ8 1.95 Å EC: 2.7.1.11 CRYSTAL STRUCTURE OF PHOSPHOFRUCTOKINASE FROM STAPHYLOCOCCUS COMPLEX WITH ADENYLYLIMIDODIPHOSPHATE (THE ATP ANALOG) AND 6 -PHOSPHATE STAPHYLOCOCCUS AUREUS (STRAIN NCTC 832ORGANISM_TAXID: 93061 PHOSPHOFRUCTOKINASE STAPHYLOCOCCUS AUREUS FRUCTOSE-6-PHOSPTRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO THE REGULATION OF STAPHYLO AUREUS PHOSPHOFRUCTOKINASE BY TETRAMER-DIMER CONVER BIOCHEMISTRY V. 57 4252 2018
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:403;
A:404;
A:402;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
F6P A:401;
 Valid;
 none;
 submit data
260.136 C6 H13 O9 P C([C@...
MG A:405;
 Invalid;
 none;
 submit data
24.305 Mg [Mg+2...
ANP A:406;
 Valid;
 none;
 submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5XZ8 1.95 Å EC: 2.7.1.11 CRYSTAL STRUCTURE OF PHOSPHOFRUCTOKINASE FROM STAPHYLOCOCCUS COMPLEX WITH ADENYLYLIMIDODIPHOSPHATE (THE ATP ANALOG) AND 6 -PHOSPHATE STAPHYLOCOCCUS AUREUS (STRAIN NCTC 832ORGANISM_TAXID: 93061 PHOSPHOFRUCTOKINASE STAPHYLOCOCCUS AUREUS FRUCTOSE-6-PHOSPTRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO THE REGULATION OF STAPHYLO AUREUS PHOSPHOFRUCTOKINASE BY TETRAMER-DIMER CONVER BIOCHEMISTRY V. 57 4252 2018
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5XZ9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 5XZA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5XZ7 - F6P C6 H13 O9 P C([C@@H]1[....
4 5XZ8 - F6P C6 H13 O9 P C([C@@H]1[....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5XZ9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 5XZA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5XZ7 - F6P C6 H13 O9 P C([C@@H]1[....
4 5XZ8 - F6P C6 H13 O9 P C([C@@H]1[....
5 4I7E Kd = 0.45 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 4I4I Kd = 2.1 uM PEP C3 H5 O6 P C=C(C(=O)O....
7 4PFK - F6P C6 H13 O9 P C([C@@H]1[....
8 1PFK - FBP C6 H14 O12 P2 C([C@@H]1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5XZ9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 5XZA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5XZ7 - F6P C6 H13 O9 P C([C@@H]1[....
4 5XZ8 - F6P C6 H13 O9 P C([C@@H]1[....
5 4I7E Kd = 0.45 uM PEP C3 H5 O6 P C=C(C(=O)O....
6 4I4I Kd = 2.1 uM PEP C3 H5 O6 P C=C(C(=O)O....
7 4PFK - F6P C6 H13 O9 P C([C@@H]1[....
8 1PFK - FBP C6 H14 O12 P2 C([C@@H]1[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: F6P; Similar ligands found: 20
No: Ligand ECFP6 Tc MDL keys Tc
1 TA6 1 1
2 F6P 1 1
3 FBP 0.666667 0.954545
4 AFP 0.666667 0.954545
5 SF6 0.564103 0.744186
6 FRU 0.564103 0.744186
7 PSV 0.564103 0.744186
8 LFR 0.564103 0.744186
9 SF9 0.564103 0.744186
10 FDP 0.55102 0.954545
11 F1X 0.531915 1
12 QIF 0.489796 0.787234
13 FRU FRU FRU FRU 0.464286 0.755556
14 FRU FRU FRU 0.464286 0.755556
15 Z9N GLC 0.45614 0.73913
16 S7P 0.444444 0.976744
17 AHG 0.431818 0.886364
18 ABF 0.404255 0.906977
19 HSX 0.404255 0.906977
20 RP5 0.404255 0.906977
Ligand no: 2; Ligand: ANP; Similar ligands found: 429
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 ADP 0.802632 0.972222
4 AP5 0.802632 0.945205
5 B4P 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 HEJ 0.772152 0.972222
10 AN2 0.769231 0.986111
11 AT4 0.769231 0.933333
12 AQP 0.7625 0.972222
13 5FA 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 APR 0.740741 0.945205
18 AR6 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 AGS 0.731707 0.921053
22 KG4 0.728395 0.92
23 AMP 0.723684 0.944444
24 A 0.723684 0.944444
25 ATF 0.717647 0.933333
26 CA0 0.716049 0.92
27 ADX 0.716049 0.851852
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 45A 0.696203 0.893333
33 AMP MG 0.692308 0.90411
34 HQG 0.681818 0.958904
35 A12 0.679012 0.933333
36 AP2 0.679012 0.933333
37 APC 0.678571 0.933333
38 TAT 0.674419 0.933333
39 T99 0.674419 0.933333
40 A22 0.674157 0.958904
41 SRA 0.670886 0.894737
42 SRP 0.670455 0.883117
43 5AL 0.666667 0.906667
44 8LE 0.666667 0.871795
45 ADP BEF 0.662651 0.917808
46 ADP MG 0.662651 0.917808
47 ADQ 0.659341 0.92
48 A1R 0.659341 0.884615
49 A3R 0.659341 0.884615
50 QA7 0.655556 0.871795
51 JNT 0.652174 0.92
52 8LH 0.651685 0.883117
53 3OD 0.648936 0.92
54 BIS 0.648936 0.909091
55 5SV 0.648352 0.82716
56 V2G 0.647727 0.897436
57 9X8 0.645161 0.896104
58 OAD 0.645161 0.92
59 25L 0.642105 0.958904
60 AMO 0.641304 0.907895
61 ANP MG 0.640449 0.958904
62 8LQ 0.637363 0.883117
63 G5P 0.636364 0.897436
64 DLL 0.634409 0.906667
65 00A 0.634409 0.860759
66 AHX 0.634409 0.897436
67 RBY 0.632184 0.907895
68 ATP MG 0.632184 0.917808
69 APC MG 0.632184 0.893333
70 ADV 0.632184 0.907895
71 ADP PO3 0.632184 0.917808
72 NB8 0.631579 0.897436
73 OZV 0.630435 0.945205
74 8QN 0.630435 0.906667
75 OOB 0.630435 0.906667
76 25A 0.630435 0.945205
77 G3A 0.626263 0.897436
78 BEF ADP 0.625 0.893333
79 4AD 0.623656 0.896104
80 PAJ 0.623656 0.8625
81 LAD 0.621053 0.839506
82 ME8 0.614583 0.819277
83 1ZZ 0.614583 0.819277
84 TXA 0.614583 0.907895
85 GTA 0.613861 0.864198
86 9ZA 0.612903 0.909091
87 9ZD 0.612903 0.909091
88 KMQ 0.612245 0.907895
89 3UK 0.610526 0.894737
90 SON 0.604651 0.907895
91 ALF ADP 0.604396 0.848101
92 VO4 ADP 0.604396 0.92
93 WAQ 0.604167 0.860759
94 B5V 0.604167 0.883117
95 PR8 0.604167 0.829268
96 4UV 0.6 0.871795
97 GAP 0.6 0.87013
98 FYA 0.597938 0.881579
99 PTJ 0.597938 0.873418
100 LMS 0.597561 0.829268
101 UP5 0.596154 0.896104
102 FA5 0.59596 0.883117
103 PAP 0.595506 0.958333
104 A4P 0.59434 0.823529
105 XAH 0.59 0.841463
106 AFH 0.588235 0.8625
107 4UU 0.588235 0.871795
108 9SN 0.585859 0.85
109 2A5 0.58427 0.894737
110 T5A 0.583333 0.821429
111 DQV 0.582524 0.932432
112 NAI 0.580952 0.884615
113 B5M 0.58 0.871795
114 B5Y 0.58 0.871795
115 ITT 0.579545 0.917808
116 ATR 0.577778 0.944444
117 OMR 0.575472 0.831325
118 5AS 0.574713 0.781609
119 YLP 0.571429 0.8
120 48N 0.571429 0.873418
121 AP0 0.570093 0.873418
122 4TC 0.570093 0.873418
123 7D3 0.569767 0.881579
124 ADJ 0.568807 0.831325
125 DAL AMP 0.568421 0.881579
126 GNP 0.568421 0.922078
127 9GM 0.568421 0.922078
128 NAX 0.566038 0.851852
129 DND 0.566038 0.907895
130 6V0 0.566038 0.873418
131 4UW 0.566038 0.839506
132 TXD 0.566038 0.884615
133 ADN 0.565789 0.821918
134 XYA 0.565789 0.821918
135 RAB 0.565789 0.821918
136 AOC 0.564706 0.8
137 7D4 0.561798 0.881579
138 ADP BMA 0.561224 0.894737
139 TYM 0.560748 0.883117
140 TXE 0.560748 0.884615
141 GA7 0.557692 0.883117
142 YLC 0.555556 0.819277
143 YLB 0.555556 0.8
144 L3W 0.555556 0.907895
145 139 0.554545 0.851852
146 5N5 0.551282 0.797297
147 JB6 0.55 0.860759
148 LAQ 0.54717 0.819277
149 F2R 0.544643 0.843373
150 MYR AMP 0.544554 0.797619
151 A4D 0.544304 0.797297
152 5CD 0.544304 0.783784
153 80F 0.54386 0.821429
154 7MD 0.542857 0.864198
155 6AD 0.542553 0.886076
156 A2R 0.541667 0.958904
157 UPA 0.541284 0.884615
158 YLA 0.540541 0.8
159 BTX 0.539823 0.821429
160 COD 0.539823 0.793103
161 G5A 0.537634 0.781609
162 HFD 0.537634 0.921053
163 JSQ 0.537634 0.921053
164 CNA 0.535714 0.907895
165 AYB 0.535714 0.790698
166 3DH 0.535714 0.753247
167 BT5 0.535088 0.811765
168 ATP A 0.533981 0.905405
169 ATP A A A 0.533981 0.905405
170 IOT 0.531532 0.811765
171 MTA 0.53012 0.753247
172 3AM 0.529412 0.90411
173 A3P 0.52809 0.944444
174 NAD 0.526316 0.906667
175 PPS 0.526316 0.851852
176 NO7 0.525773 0.907895
177 EP4 0.52439 0.734177
178 7D5 0.52381 0.855263
179 AMP DBH 0.52381 0.87013
180 J7C 0.522727 0.75
181 H1Q 0.521739 0.88
182 A5A 0.520833 0.809524
183 EAD 0.520661 0.851852
184 TSB 0.520408 0.821429
185 AHZ 0.518519 0.797619
186 M2T 0.518072 0.716049
187 DTA 0.518072 0.766234
188 6RE 0.517241 0.740741
189 A3D 0.517241 0.894737
190 YLY 0.516949 0.790698
191 SSA 0.515464 0.802326
192 NA7 0.514852 0.933333
193 AR6 AR6 0.514019 0.893333
194 ARG AMP 0.514019 0.809524
195 7MC 0.513514 0.843373
196 A2P 0.511111 0.930556
197 VMS 0.510204 0.790698
198 54H 0.510204 0.790698
199 52H 0.510204 0.781609
200 TAD 0.509259 0.8625
201 NAQ 0.508333 0.85
202 A3N 0.505618 0.766234
203 CUU 0.505376 0.945205
204 AV2 0.505155 0.893333
205 53H 0.50505 0.781609
206 5CA 0.50505 0.802326
207 8X1 0.50505 0.755556
208 ARU 0.504951 0.839506
209 ZID 0.504132 0.894737
210 P1H 0.504 0.831325
211 AVV 0.5 0.873418
212 6MZ 0.5 0.905405
213 NAE 0.5 0.871795
214 3AT 0.5 0.945205
215 P5A 0.495146 0.747253
216 NSS 0.49505 0.802326
217 LSS 0.49505 0.764045
218 DSZ 0.49505 0.802326
219 N0B 0.491803 0.8
220 38V 0.491803 0.864198
221 ALF ADP 3PG 0.491071 0.817073
222 AF3 ADP 3PG 0.491071 0.817073
223 NVA LMS 0.490196 0.755556
224 O02 0.489583 0.922078
225 DAT 0.489362 0.881579
226 IMO 0.488889 0.90411
227 ZAS 0.488636 0.792208
228 FDA 0.488372 0.813953
229 NWW 0.487805 0.739726
230 D4F 0.487603 0.819277
231 NAJ PZO 0.487395 0.85
232 4TA 0.487179 0.788235
233 NAD TDB 0.486726 0.893333
234 NAD IBO 0.486726 0.893333
235 LPA AMP 0.486486 0.797619
236 DTP 0.484536 0.881579
237 V3L 0.484536 0.945205
238 GJV 0.483516 0.731707
239 S4M 0.483516 0.651685
240 DZD 0.483051 0.8625
241 2AM 0.482759 0.917808
242 5AD 0.481013 0.726027
243 KAA 0.480769 0.755556
244 GSU 0.480769 0.781609
245 NDE 0.480315 0.907895
246 M24 0.479339 0.851852
247 MAO 0.478261 0.761905
248 DSH 0.477778 0.707317
249 NEC 0.477778 0.727273
250 FAD 0.477273 0.831325
251 FAS 0.477273 0.831325
252 RGT 0.476636 0.933333
253 9K8 0.47619 0.698925
254 0WD 0.474576 0.897436
255 FNK 0.474074 0.786517
256 5X8 0.473684 0.74359
257 6FA 0.473282 0.821429
258 NDC 0.472868 0.85
259 FB0 0.472868 0.786517
260 YSA 0.472222 0.781609
261 LEU LMS 0.471154 0.733333
262 7DD 0.468085 0.958333
263 OVE 0.466667 0.881579
264 NWQ 0.465909 0.72
265 DZ4 0.464646 0.907895
266 MHZ 0.463158 0.701149
267 8PZ 0.462963 0.802326
268 AMP NAD 0.462185 0.881579
269 A3G 0.461538 0.779221
270 N5O 0.461538 0.74359
271 NAJ PYZ 0.459677 0.809524
272 6C6 0.459184 0.858974
273 B1U 0.458716 0.758242
274 LQJ 0.458716 0.893333
275 SFG 0.458333 0.730769
276 7D7 0.45679 0.723684
277 128 0.45614 0.8
278 SFD 0.455224 0.736842
279 DDS 0.454545 0.855263
280 GDP 0.454545 0.896104
281 6IA 0.454545 0.817073
282 NJP 0.453782 0.921053
283 ODP 0.453782 0.886076
284 7DT 0.453608 0.958333
285 J4G 0.45283 0.896104
286 A7D 0.452632 0.75641
287 Z5A 0.452381 0.802326
288 WSA 0.452174 0.790698
289 N5A 0.451613 0.717949
290 7C5 0.45045 0.797468
291 K3K 0.449541 0.782051
292 FAY 0.449275 0.841463
293 NDP 0.449153 0.897436
294 SA8 0.44898 0.690476
295 A5D 0.44898 0.766234
296 71V 0.446809 0.884615
297 GGZ 0.446602 0.804878
298 RFL 0.446043 0.802326
299 2SA 0.445545 0.907895
300 SAH 0.444444 0.725
301 SAI 0.444444 0.716049
302 GP3 0.444444 0.897436
303 PO4 PO4 A A A A PO4 0.443396 0.878378
304 QXG 0.443396 0.77907
305 4YB 0.442478 0.764045
306 QXP 0.442308 0.788235
307 K3E 0.441441 0.772152
308 S7M 0.441176 0.674419
309 SMM 0.441176 0.670455
310 GTP 0.441176 0.896104
311 V47 0.441176 0.763158
312 Y3J 0.440476 0.706667
313 SAM 0.44 0.674419
314 649 0.439655 0.747253
315 12D 0.438596 0.809524
316 A3S 0.4375 0.789474
317 NPW 0.436975 0.864198
318 GCP 0.436893 0.873418
319 EEM 0.435644 0.674419
320 AAT 0.435644 0.690476
321 GNH 0.435644 0.909091
322 ETB 0.435484 0.813953
323 DCA 0.435484 0.804598
324 KOY 0.434783 0.782051
325 N6P 0.433962 0.890411
326 NZQ 0.433333 0.886076
327 TXP 0.433333 0.897436
328 PGS 0.43299 0.860759
329 APU 0.432203 0.871795
330 PUA 0.432 0.8625
331 62F 0.431655 0.841463
332 F2N 0.431507 0.795455
333 DA 0.430108 0.855263
334 D5M 0.430108 0.855263
335 J7V 0.429688 0.813953
336 0T1 0.428571 0.804598
337 A3T 0.428571 0.8
338 COA 0.428571 0.804598
339 NIA 0.428571 0.848101
340 6K6 0.428571 0.905405
341 P5F 0.427586 0.804598
342 R2V 0.425926 0.788235
343 CZF 0.425743 0.906667
344 NX8 0.425743 0.698795
345 AAM 0.425532 0.944444
346 KYB 0.424528 0.714286
347 0UM 0.424528 0.682353
348 8Q2 0.423729 0.775281
349 G1R 0.423077 0.884615
350 AMZ 0.422222 0.891892
351 C2R 0.422222 0.88
352 QBQ 0.421569 0.883117
353 IDP 0.42 0.894737
354 K2W 0.419643 0.722892
355 KY2 0.419048 0.714286
356 GSP 0.419048 0.851852
357 1DG 0.418605 0.897436
358 COS 0.418605 0.786517
359 CAO 0.418605 0.777778
360 DG1 0.418605 0.897436
361 30N 0.418605 0.736842
362 AMX 0.418605 0.813953
363 KY5 0.418182 0.707317
364 TM1 0.418182 0.797619
365 9BG 0.418033 0.873418
366 A6D 0.416667 0.746988
367 K15 0.416667 0.666667
368 V1N 0.415929 0.893333
369 SCO 0.415385 0.804598
370 CMX 0.415385 0.804598
371 GEK 0.415094 0.719512
372 NHD 0.414634 0.881579
373 XNP 0.414634 0.851852
374 K38 0.414414 0.759494
375 9JJ 0.413793 0.841463
376 AIR 0.413793 0.876712
377 COK 0.413534 0.786517
378 K2K 0.412844 0.719512
379 G2R 0.412844 0.8625
380 KY8 0.412844 0.710843
381 FAM 0.412214 0.786517
382 FCX 0.412214 0.777778
383 ACO 0.412214 0.777778
384 KL2 0.411111 0.815789
385 NAP 0.410853 0.92
386 NWZ 0.41 0.686747
387 CNV FAD 0.409722 0.775281
388 FA9 0.409396 0.843373
389 SXZ 0.409091 0.694118
390 K2R 0.409091 0.857143
391 O05 0.409091 0.823529
392 HAX 0.409091 0.806818
393 TAP 0.407692 0.884615
394 62X 0.407407 0.651685
395 2MC 0.407407 0.752688
396 K2H 0.407407 0.7375
397 GKE 0.40708 0.8625
398 GDD 0.40708 0.8625
399 GDC 0.40708 0.8625
400 KYE 0.40708 0.697674
401 FYN 0.406015 0.804598
402 3KK 0.406015 0.786517
403 NVA 2AD 0.405941 0.740741
404 KXW 0.405172 0.690476
405 PLP AAD 0.404762 0.736264
406 NA0 0.40458 0.907895
407 101 0.404255 0.855263
408 G 0.40404 0.883117
409 5GP 0.40404 0.883117
410 FAJ 0.403974 0.811765
411 HDV 0.403846 0.87013
412 MGP 0.403846 0.8625
413 MCD 0.402985 0.786517
414 OXK 0.402985 0.786517
415 YZS 0.402985 0.714286
416 KGP 0.402985 0.714286
417 SOP 0.402985 0.786517
418 CA6 0.402985 0.714286
419 3AD 0.402299 0.783784
420 S8M 0.401869 0.78481
421 YE1 0.40146 0.795455
422 2VA 0.4 0.779221
423 6G0 0.4 0.8625
424 NMX 0.4 0.782609
425 CO6 0.4 0.786517
426 1VU 0.4 0.777778
427 GMV 0.4 0.873418
428 7RP 0.4 0.902778
429 CMC 0.4 0.786517
Similar Ligands (3D)
Ligand no: 1; Ligand: F6P; Similar ligands found: 438
No: Ligand Similarity coefficient
1 M6P 0.9518
2 G6P 0.9506
3 GLP 0.9456
4 M6D 0.9452
5 D6G 0.9396
6 3LJ 0.9318
7 TU0 0.9304
8 BG6 0.9272
9 NPL 0.9245
10 PLP 0.9203
11 PLR 0.9200
12 F1P 0.9186
13 A6P 0.9184
14 UFO 0.9164
15 4R1 0.9129
16 APZ 0.9123
17 GJK 0.9118
18 PTS 0.9115
19 PMP 0.9102
20 PXP 0.9099
21 C9M 0.9077
22 FER 0.9070
23 GRF 0.9065
24 6ME 0.9041
25 PAL 0.9027
26 I6G 0.9024
27 SSY 0.9021
28 N88 0.9019
29 QX4 0.9018
30 RGG 0.9016
31 MP5 0.9014
32 XQK 0.9010
33 20J 0.9008
34 2D3 0.9006
35 N7I 0.9006
36 MOK 0.9002
37 8W9 0.8997
38 1VQ 0.8995
39 LRW 0.8993
40 YO5 0.8988
41 SYR 0.8988
42 AZY 0.8977
43 PZP 0.8977
44 PLP PMP 0.8977
45 CIY 0.8969
46 9C2 0.8966
47 PH2 0.8961
48 DQU 0.8959
49 PA5 0.8959
50 A5P 0.8958
51 C9E 0.8956
52 RP3 0.8951
53 STT 0.8948
54 SXS 0.8946
55 HE8 0.8945
56 IL5 0.8943
57 4TP 0.8938
58 GM7 0.8938
59 GJS 0.8935
60 5WM 0.8933
61 NIY 0.8933
62 5WN 0.8931
63 IOP 0.8930
64 HBO 0.8930
65 I2E 0.8929
66 R1P 0.8929
67 OTW 0.8927
68 1QV 0.8923
69 GZ8 0.8923
70 QR2 0.8920
71 QAT 0.8918
72 CTN 0.8916
73 JVA 0.8911
74 GT1 0.8908
75 4V6 0.8904
76 3TJ 0.8902
77 GPM 0.8902
78 GL6 0.8902
79 CWS 0.8901
80 B62 0.8900
81 BGP 0.8899
82 8CM 0.8899
83 6PR 0.8898
84 39O 0.8896
85 3Z8 0.8895
86 QAS 0.8894
87 V2Z 0.8891
88 N8Y 0.8891
89 R5P 0.8890
90 KUF 0.8890
91 FDR 0.8888
92 IPD 0.8887
93 0P6 0.8885
94 DXP 0.8884
95 44W 0.8883
96 MVN 0.8883
97 G1P 0.8880
98 LXP 0.8879
99 M1P 0.8877
100 5SP 0.8874
101 CKU 0.8874
102 HHR 0.8873
103 14W 0.8872
104 GFP 0.8868
105 KWB 0.8868
106 B5D 0.8867
107 XHP 0.8864
108 7WR 0.8863
109 OSB 0.8862
110 TRP 0.8862
111 HQD 0.8861
112 RCV 0.8860
113 DPZ 0.8859
114 PMV 0.8858
115 DNA 0.8858
116 GDE 0.8855
117 Q71 0.8854
118 V1T 0.8852
119 VK3 0.8852
120 YTX 0.8842
121 49N 0.8841
122 Q77 0.8841
123 KT7 0.8841
124 0FO 0.8840
125 DHC 0.8836
126 44V 0.8833
127 5P3 0.8830
128 NFZ 0.8829
129 2FQ 0.8829
130 2V0 0.8828
131 9BF 0.8826
132 TYU 0.8824
133 L7T 0.8823
134 2GQ 0.8823
135 0FK 0.8821
136 BEA 0.8821
137 NBG 0.8819
138 CLZ 0.8818
139 M7P 0.8816
140 YQA 0.8813
141 5VJ 0.8813
142 IBM 0.8812
143 KGK 0.8808
144 O2Y 0.8808
145 8MO 0.8807
146 X04 0.8804
147 NHT 0.8804
148 JKZ 0.8804
149 MRU 0.8802
150 2K8 0.8801
151 9F8 0.8800
152 8HC 0.8798
153 R52 0.8797
154 F69 0.8797
155 6NZ 0.8793
156 JR2 0.8793
157 BPU 0.8790
158 PBG 0.8790
159 CR1 0.8790
160 EGR 0.8787
161 QMS 0.8786
162 URC 0.8786
163 VXX 0.8781
164 D5X 0.8780
165 GC3 0.8779
166 UFV 0.8778
167 60Q 0.8776
168 9GP 0.8775
169 H5B 0.8775
170 AC2 0.8774
171 URI 0.8774
172 DAH 0.8774
173 FLV 0.8773
174 4FE 0.8771
175 NAG 0.8771
176 6DP 0.8769
177 VM1 0.8766
178 97T 0.8766
179 M3Q 0.8765
180 4Z9 0.8764
181 NLQ 0.8764
182 5OO 0.8763
183 49O 0.8762
184 DER 0.8761
185 P80 0.8760
186 LT8 0.8760
187 STV 0.8758
188 5NS 0.8758
189 EJZ 0.8758
190 5GT 0.8758
191 SG2 0.8757
192 TQU 0.8754
193 Z5P 0.8753
194 5RP 0.8753
195 LSQ 0.8752
196 5F8 0.8752
197 HKD 0.8752
198 HPT 0.8751
199 H35 0.8751
200 RVE 0.8751
201 JV4 0.8750
202 PRF 0.8749
203 AMG 0.8749
204 49P 0.8745
205 61O 0.8744
206 G6Q 0.8744
207 AMR 0.8744
208 LTN 0.8744
209 MTS 0.8743
210 4XV 0.8743
211 JTH 0.8743
212 1Z8 0.8739
213 DEE 0.8738
214 GCB 0.8737
215 HHS 0.8736
216 LDR 0.8735
217 GCU 0.8734
218 N2M 0.8734
219 OA3 0.8733
220 Q5M 0.8733
221 DNC 0.8731
222 U7E 0.8730
223 5FL 0.8730
224 KFH 0.8730
225 SXX 0.8729
226 ALA PRO 0.8728
227 26E 0.8728
228 7ZL 0.8727
229 P4L 0.8727
230 ZYR 0.8726
231 2OR 0.8725
232 6HP 0.8724
233 86J 0.8723
234 GTR 0.8722
235 R10 0.8722
236 HLZ 0.8721
237 M3N 0.8719
238 QSH 0.8719
239 0LO 0.8717
240 SNR 0.8716
241 F6R 0.8714
242 VNL 0.8713
243 RDY 0.8713
244 8U3 0.8712
245 FA6 0.8712
246 CBF 0.8711
247 LEL 0.8711
248 BDP 0.8710
249 2HC 0.8708
250 EXD 0.8708
251 78P 0.8707
252 5F5 0.8707
253 GC2 0.8706
254 2UZ 0.8706
255 DXK 0.8705
256 AVA 0.8704
257 LSA 0.8703
258 4ME 0.8701
259 GTC 0.8701
260 MBG 0.8700
261 23J 0.8699
262 3IL 0.8699
263 EWG 0.8699
264 F40 0.8698
265 RXA 0.8698
266 363 0.8696
267 LZ2 0.8696
268 92P 0.8695
269 28N 0.8695
270 1X4 0.8691
271 6PG 0.8691
272 ZIP 0.8690
273 P7Y 0.8685
274 RKV 0.8684
275 KTW 0.8683
276 MWP 0.8683
277 BM3 0.8682
278 SYA 0.8682
279 DG2 0.8681
280 DHK 0.8680
281 1N4 0.8678
282 GO8 0.8678
283 M0Q 0.8676
284 5E5 0.8676
285 IOS 0.8674
286 495 0.8673
287 0F9 0.8673
288 4KL 0.8671
289 GYP 0.8669
290 M3L 0.8669
291 KDN 0.8668
292 NQ 0.8668
293 IPT 0.8667
294 K3Q 0.8666
295 SQP 0.8666
296 TB8 0.8665
297 ZZU 0.8663
298 6Q3 0.8663
299 2UD 0.8662
300 6J5 0.8662
301 J9Q 0.8662
302 B41 0.8659
303 5FN 0.8657
304 EVA 0.8657
305 MPK 0.8657
306 61M 0.8657
307 L22 0.8655
308 MIL 0.8655
309 0N7 0.8654
310 JF1 0.8652
311 NTF 0.8651
312 DCZ 0.8651
313 DUR 0.8648
314 DIN 0.8648
315 R8V 0.8648
316 0W1 0.8646
317 4XS 0.8646
318 7I2 0.8645
319 AHL 0.8643
320 GOX 0.8642
321 NPA 0.8641
322 3D8 0.8639
323 YOF 0.8637
324 XXG 0.8636
325 I4D 0.8636
326 DI6 0.8634
327 NOK 0.8634
328 HMQ 0.8634
329 YIP 0.8633
330 I5A 0.8633
331 KYA 0.8632
332 MUR 0.8631
333 Q6T 0.8630
334 F5C 0.8629
335 ONR 0.8629
336 57O 0.8628
337 KYN 0.8627
338 APS 0.8624
339 MRW 0.8624
340 293 0.8620
341 ALE 0.8619
342 8XQ 0.8619
343 TZP 0.8618
344 AEH 0.8618
345 4XF 0.8614
346 MMS 0.8613
347 ESI 0.8612
348 OMD 0.8612
349 4U7 0.8612
350 ZME 0.8611
351 B4O 0.8609
352 CFA 0.8608
353 KBR 0.8608
354 289 0.8607
355 ZEZ 0.8607
356 EQA 0.8605
357 PW1 0.8605
358 1QP 0.8604
359 9PY 0.8604
360 PRZ 0.8603
361 9KT 0.8601
362 FXH 0.8601
363 3C5 0.8601
364 IYR 0.8600
365 4NO 0.8599
366 NQH 0.8599
367 TZM 0.8599
368 ZEA 0.8599
369 IVL 0.8597
370 GLS 0.8596
371 C1F 0.8596
372 H7Y 0.8595
373 GL1 0.8595
374 CHQ 0.8594
375 7ZE 0.8593
376 MUX 0.8592
377 4TU 0.8592
378 3Y7 0.8591
379 BP7 0.8591
380 8NX 0.8589
381 TWO 0.8587
382 OX2 0.8584
383 878 0.8584
384 X6W 0.8582
385 A1Y 0.8582
386 BY5 0.8582
387 MT8 0.8580
388 091 0.8580
389 CKX 0.8579
390 ZEC 0.8577
391 7ME 0.8576
392 8TX 0.8576
393 JF2 0.8576
394 8G6 0.8575
395 KLV 0.8574
396 2O6 0.8574
397 AX3 0.8573
398 5QX 0.8572
399 4BX 0.8571
400 4HC 0.8571
401 J9W 0.8570
402 5TO 0.8569
403 4GP 0.8568
404 8NB 0.8567
405 X48 0.8566
406 XM5 0.8565
407 R9Y 0.8565
408 ZON 0.8565
409 RBV 0.8563
410 BGT 0.8563
411 HNQ 0.8563
412 DX3 0.8562
413 3SU 0.8562
414 QIV 0.8561
415 2KA 0.8561
416 ADA 0.8560
417 LL1 0.8558
418 96Z 0.8558
419 GZ2 0.8556
420 5WY 0.8554
421 ROI 0.8551
422 W8G 0.8550
423 1FE 0.8549
424 GAL 0.8549
425 2LT 0.8548
426 16G 0.8543
427 ACE PHE 0.8543
428 C4E 0.8542
429 S6P 0.8540
430 K2P 0.8539
431 680 0.8538
432 F06 0.8536
433 0FN 0.8536
434 DBX 0.8534
435 CL9 0.8523
436 SRO 0.8522
437 ASE 0.8521
438 SER PRO 0.8515
Ligand no: 2; Ligand: ANP; Similar ligands found: 33
No: Ligand Similarity coefficient
1 ADP AF3 0.9867
2 ADP VO4 0.9840
3 ADP ALF 0.9835
4 BEF GDP 0.9733
5 GDP BEF 0.9732
6 ALF GDP 0.9572
7 DBG 0.9557
8 GDP ALF 0.9557
9 GDP AF3 0.9523
10 UTP 0.9434
11 DGT 0.9413
12 CTP 0.9332
13 UNP 0.9314
14 GDP MG 0.9298
15 8DG 0.9119
16 MGT 0.9080
17 TTP 0.9060
18 DUP 0.9039
19 GH3 0.8961
20 Y9Z 0.8940
21 MGO 0.8925
22 2TM 0.8903
23 2KH 0.8853
24 DUT 0.8825
25 DUT MG 0.8783
26 M7G 0.8756
27 GTP MG 0.8746
28 DCP 0.8734
29 DGI 0.8732
30 ALF 5GP 0.8646
31 RSN 0.8624
32 DCT 0.8623
33 G2P 0.8610
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5XZ8; Ligand: F6P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 5xz8.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 5XZ8; Ligand: F6P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 5xz8.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 5XZ8; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 5xz8.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 5XZ8; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 5xz8.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
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